CH717410A2 - Procedure and personalized dermo-aesthetic system to treat multiple cosmetic skin problems with a single treatment. - Google Patents

Abstract

A method of personalized dermocosmetic treatment to treat one or more cosmetic skin problems in a single treatment, comprising the following phases: a) Creation of several cosmetic preparations, each of which contains mixtures of cosmetically active principles, and several cosmetic bases for the cosmetic compositions infiltrate, b) selection of one or more cosmetic preparations from several available cosmetic preparations depending on the type of blemish to be treated of the skin and mixing one or more selected preparations with a cosmetic base to form a cosmetic composition, c) application of a cosmetically effective Amount of the cosmetic composition prepared in phase b) on the person's skin.

Description

The present invention relates to a method and a system for personalized dermo-aesthetic treatment.

The present invention has its origin in the sector of dermocosmetics.

In particular, the invention relates to a system for personalizing a dermo-aesthetic treatment based on the combination of cosmetically active ingredients selected by the user based on the specific indications of the method and personal requirements, and their mixture with a cosmetic base at the time of Application of the product.

STATE OF THE ART

The products for cosmetic use currently available on the market are formulated by cosmetic companies on the basis of the skin type and the aesthetic problem to be treated.

Typically, the skin types are divided into macro categories such as normal skin, dry skin, combination skin, oily skin and mature skin, while the most common aesthetic problems affecting the skin, spots, wrinkles, facial wrinkles, dark circles, acne, etc. . include.

In general, the cosmetic products currently available on the market are formulated to treat a single cosmetic problem of the skin.

The skin condition, however, is influenced by a combination of factors of an endogenous and exogenous nature.

The factors of an endogenous nature include genetic factors, hormonal or pathological conditions and the age of the patient. The exogenous factors include lifestyle habits, climatic conditions, exposure to external influences such as mainly sunlight, smog and wind. These factors can affect the physiological condition of the skin by causing changes in texture, moisture content and pH.

The extreme variability of skin type leads to the need to search for and determine the most suitable cosmetic product for each person's skin.

However, personalized cosmetic therapies for skin treatment do not currently exist and in most cases the cosmetic products available are directed towards treating a skin type that falls under one of the following general categories: dry skin, normal skin, combination skin, oily skin, mature skin . Otherwise, the cosmetic products available on the market are aimed at treating the most common dermocosmetic problems, such as blotchy skin, dark circles and wrinkles.

Currently, the majority of cosmetic products have suitable formulations to treat a single aesthetic problem. The demand for multifactorial cosmetic products that are able to treat different types of blemishes on the skin with a single formulation is therefore neglected.

There is also an increasing demand for personalized cosmetic products, the formulation of which reflects various specific aesthetic demands of the person.

The present invention therefore originated in the need to provide a dermo-aesthetic response to multiple and / or accompanying aesthetic problems, using a cosmetic treatment to address multiple problems with a single treatment.

One of the objects of the present invention is to provide a method of cosmetic treatment that is personalized or customizable based on blemishes or cosmetic problems of the individual.

Another object is to provide a method and / or a system for dermo-aesthetic treatment of the skin with a formulation that includes one or more cosmetically effective ingredients, depending on the various types of blemishes / cosmetic problems to be treated Skin to be selected.

SUMMARY OF THE INVENTION

The applicant has developed a method or system for cosmetic treatment that allows a person in need of treatment to select one or more cosmetically active ingredients from several ingredients, depending on their own different requirements of an aesthetic nature, and in this way personalize their own treatment based on the various blemishes being treated. In addition, the method developed by the applicant allows several cosmetic problems or blemishes to be treated, advantageously up to a maximum of 3 cosmetic problems, with a single treatment.

According to one aspect, the present invention relates to a system or method for dermocosmetic treatment, which is advantageously personalized in order to treat one or more cosmetic problems of the skin in a single treatment, which comprises the following phases: a) creation of several cosmetic preparations, preferably 10, each of which contains mixtures of cosmetically active principles, and several cosmetic bases, preferably 4, to infiltrate the cosmetic compositions, b) selection of one or more cosmetic preparations from several available cosmetic preparations depending on the type of skin blemish to be treated and mixing one or more selected preparations with a cosmetic base in order to form a cosmetic composition, c) applying a cosmetically effective amount of the cosmetic composition prepared in phase b) to the skin of the person in need of treatment.

The method / system described above preferably provides the possibility of choosing from one to three cosmetic preparations of phase a) and of mixing them with one of the cosmetic bases of phase b) and optionally one for mixture a + b to add further cosmetic preparation c) and then to apply the composition obtained to the skin.

According to another aspect, the present invention relates to an advantageously personalized dermo-aesthetic set in order to treat one or more cosmetic problems of the skin in a single treatment, which comprises: several cosmetic preparations, preferably ten, each of which contains cosmetically active principles to be mixed with a cosmetic base, several cosmetic bases, preferably four, in order to introduce the cosmetically active principles of one or more cosmetic preparations, and optionally several (extra) cosmetic preparations, preferably five, each of which contains cosmetically active principles to be added to the cosmetic bases.

In an embodiment shown in the accompanying figure, the cosmetic set according to the invention comprises three components: a first component comprises 10 cosmetic preparations, each of which is suitable for treating a specific skin problem; a second component comprising 4 cosmetic carriers / bases intended to be mixed with the cosmetic preparations of the system, and optionally an optional third component comprising 5 cosmetic preparations, each of which is suitable for treating a specific skin problem;

In particular, the first component of the set or system comprises the following 10 cosmetic preparations 1 7 growth factors wrinkles and microrelief anti-wrinkle effect and skin regeneration 2 3 collagens, relaxing peptide deep wrinkles and furrows anti-wrinkle effect, smoothing wrinkle filler 3 2 elastins, thickening peptide sagging skin lifting effect 4 Omega 3-6-9 Anti-Aging, Mature Skin Reconstructive, Anti-Aging 5 Vitamin C, Shimmering Peptide Pale Skin Lightening Effect 6 Kojic Acid, Glycolic Acid Blotchy Skin Reduction of Dark Spots 7 Panthenol, Bisabolol Couperose, irritated skin Soothing, reddening effect 8 B-group vitamins Dehydrated and dry skin Moisturizing and nourishing 9 Vitamin H, azelaic acid sebum and enlarged pores Mattifying and refining effect 10 Centella, hesperidin bags under the eyes and dark circles Dehydrating and depigmenting effect

The second component comprises the following transdermal carriers, which are also specified as cosmetic bases: Base 1 Rich Emulsion Soft and velvety Base 2 Light Emulsion Moisturizing, silky Base 3 Oil-Free Emulsion Fresh, without oils Base 4 Eye and Lip Emulsion eye and lip contour

The third - optional - component of the system comprises the following cosmetic preparations 1 7 hyaluronic acids plumping effect 2 20 amino acids structuring effect on the skin 3 vitamin A renewing effect on the skin 4 vitamin E, resveratrol antioxidant, detoxifying effect 5 6 minerals remineralization of the skin

The inventive method for cosmetic treatment comprises mixing one or more of the cosmetic preparations of component 1 with one of the transdermal bases of component 2 and applying the combination to the skin.

One of the main advantages lies in the fact that the dermoesthetic method / set according to the invention is personalized and suitable for treating one or more cosmetic or aesthetic problems of a person's skin with a single cosmetic treatment.

According to some embodiments, the system according to the invention further comprises a container, for example in the form of a circular bowl, and a mixing means, usually a spatula, in order to mix the cosmetic preparations with the cosmetic base.

DETAILED DESCRIPTION OF THE INVENTION

According to a first aspect, the present invention offers a personalized method to treat aesthetic defects or blemishes of the skin by enabling the person to choose from several cosmetic preparations those most suitable for their own requirements, with a suitable cosmetic one Mix base to apply the preparations to the skin of a person in need of treatment and smuggle into them and to treat multiple blemishes or cosmetic problems with a single treatment.

According to a first aspect, a method for cosmetic treatment is offered as defined in the attached claim 1.

Embodiments of the method according to the invention are defined in the accompanying dependent claims 2-8.

The applicant has determined a group of cosmetic preparations (components 1 and 3), which contain selected active ingredients that are provided with a highly efficient dermo-aesthetic activity, selected at the time of application, combined and with a cosmetic base (component 2) Can be mixed to perform a personalized cosmetic treatment.

Advantageously, the cosmetic preparations can be selected up to a maximum of three by the person in need of treatment depending on the type of blemish to be treated, such as facial wrinkles or wrinkled skin as a result of age-related or light-related skin aging. The selected cosmetic preparations are combined with one of the four cosmetic bases. It is optionally possible to add another cosmetic preparation that is selected from five optionally available.

For example, the method provides the possibility of using one to three cosmetic preparations in order to treat three different types of blemishes on a person's skin at the same time.

The inventors have worked out a scheme with which the person in need of treatment can determine their skin condition to be treated. With this scheme, which is described in detail below, every person will find the most suitable and effective cosmetic preparation with high concentration associated with each skin problem in order to achieve a precise dermo-aesthetic effect.

According to some embodiments, component 1 of the system consists of 10 cosmetic preparations, optional component 3 consists of 5 cosmetic preparations and component 2 consists of 4 cosmetic bases that are intended to be used with the cosmetic preparations of components 1 and 3 to be mixed up.

According to some embodiments, the components of the system have the following formulations.

First component of the procedure / system or set

The first component of the system contains 10 cosmetic preparations which have the following composition and cosmetic effect.

Cosmetic preparation 1

A first cosmetic preparation contains 7 growth factors with anti-wrinkle and skin-regenerating effects for the treatment of wrinkles and microreliefs, which are a mixture of the following growth factors: Synthetic human acidic fibroblast growth factor or Sh polypeptide-11 Synthetic human basic fibroblast growth factor or Sh polypeptide-1 Synthetic human keratinocyte growth factor or Sh polypeptide-3 Synthetic human insulin like 1 growth factor or Sh-oligopeptide-2 Synthetic Human Platelet Derived Growth Factor or Sh-Polypeptide-8 Synthetic Human Connective Tissue Growth Factor or Sh-Polypeptide-93 Synthetic Human Transforming Growth Factor Beta 3 or Sh Polypeptide 5

These components with a cosmetic effect activate the mechanisms of skin regeneration and counteract the slowing down of the cellular turnover of the epidermis and the breakdown of the structures of the dermis. The effects achieved are the reduction of wrinkles and a smooth, renewed skin.

Cosmetic preparation 2

A second cosmetic preparation that can be used in the process according to the invention is a mixture of the following 3 collagens: hydrolyzed collagen with an average molecular weight of 2K Da, hydrolyzed collagen with an average molecular weight of 12H Da, soluble collagen 300K Da, with the relaxing peptide acetyloctapeptide-3. This component has a filling and smoothing effect on the skin and is used cosmetically in the treatment of deep wrinkles and furrows caused by facial expressions, dynamic wrinkles for a time that are only visible in facial expressions that become static in the long term, wrinkles become visible even at rest.

The three collagen molecules penetrate into the dermis and support the restoration of the extracellular matrix, that is, the physiological filling of the deepest skin layers. The smoothing effect is ensured by a relaxing dermocosmetic molecule, acetyloctapeptide-3, which acts on the level of the skin's microcontractions and facilitates the smoothing of expression lines.

Cosmetic preparation 3

A third cosmetic preparation comprises two elastins and a densifying peptide with lifting effect, which are suitable for the treatment of sagging skin, which typically manifests itself in sunken facial features, undefined facial oval and sagging or sagging skin. The cause of slackening of the skin lies in the decrease in the number and the decreased hold of the fibers, which disorganize and lose elasticity and turgor.

The ingredients of this component comprise a hydrolyzed elastin molecule with a molecular weight of 1.4 K Da and a hydrolyzed elastin with a molecular weight of 2.2K Da and acetyltetrapeptide-2 (Ac-Lys-Asp-Val-Tyr-OH, with the formula C26H39N5O9 ) in its function as a skin-compacting component that acts against gravity. Elastin is the protein that allows tissue to return to its original shape after being subjected to forces of stretch and contraction, allows the skin to counteract sagging and aids the lifting effect, while the dermocosmetic skin thickening component allows the skin fibers to be firmer To condense appearance again.

Cosmetic preparation 4

A fourth cosmetic preparation comprises polyunsaturated omega-3-6-9 acids which act in the treatment of age-related skin aging and are suitable for the treatment of mature skin. Mature skin presents numerous problems in connection with the age- and light-related skin aging process, which manifest themselves primarily at the skin cell level. The skin cells fail to carry out their physiological activities as they do with young skin, the processes are slowed down and the skin appears devitalized, tired and wrinkled. Omega-3-6-9 are essential fatty acids that our organism does not produce autonomously. They offer a remarkable variety of effects and benefits to the skin, mainly because they are a fundamental part of the cell membranes that allow the integrity of the skin to be maintained and its proper self-regulation, and especially because they are able to protect the keratinocytes and the Protect fibroblasts from the damage caused by light-induced skin aging and help the skin to look younger and more vital again. The omega 3-6-9 fatty acids are preferably omega3-6-9 acids.

Cosmetic preparation 5

The fifth cosmetic preparation comprises vitamin C and oligopeptide-68, also indicated as a shimmer-imparting peptide. This component has a lightening and shimmering effect on the skin and is suitable for the treatment of pale complexions. Sallow and gray skin is due to the formation of a thick and dull layer of horn that prevents the skin from looking transparent and glowing. It can form after repeated exposure to UV radiation or due to reduced exchange of corneocytes, which solidify with one another and produce a hard, leathery epidermal surface with a grayish tint. Vitamin C (tocopheryl acetate) has antioxidant and protective properties, counteracts the formation of melanin at the skin level and reduces excessive skin pigmentation. Oligopeptide-68 or TGF-β1 biomimetic is a biomimetic peptide that, by inhibiting the activity of tyrosinase in synergy with vitamin C, interrupts the synthesis process of melanin and promotes the radiance of the skin in order to regain a healthy and radiant complexion. Typically, oligopeptide-68 is a complex peptide combination of the agonist of TGF-ss, which inhibits the microphthalmia-associated transcription factor MITF, an important transcriptional regulator of the enzymes, tyrosinase, of TRP-1 and TRP-2 melanogenic.

Cosmetic preparation 6

The sixth cosmetic preparation comprises kojic acid, glycolic acid. This component is used for the treatment of blotchy skin. Skin spots are formed by a build-up of melanin in the superficial layers of the epidermis. The problem is related to biographical and hormonal factors (age) as well as damage from light-induced skin aging (UV radiation), which disorganizes the melanin responsible for the constitutional coloring of the skin and accumulates it in increasingly visible places that over time become dark spots or areas that are tinted differently than your skin. Kojic acid and glycolic acid are effective principles with high depigmenting and lightening effects, which help to reduce dark spots and color changes and help to renew the superficial layers of the skin and give them a uniform color.

Cosmetic preparation 7

The seventh cosmetic preparation has a soothing, calming and reddening-reducing effect and comprises panthenol and bisabolol and is used in the treatment of couperose or irritated skin. Very sensitive skin can be easily irritated, reddened and made uncomfortable or burning. Redness is often caused by the weakness of the capillaries of the face, which expand due to aggressive external influences and become visible on the surface. Panthenol (provitamin B5) and bisabolol (a molecule derived from chamomile) have a strong soothing and reddening effect. Their effect favors a strengthening and protective effect and reduces the intensity of the reactions to aggressive external influences or to individual physiological conditions.

Cosmetic preparation 8

The eighth cosmetic preparation has a moisturizing and nourishing effect on the skin, is used in the treatment of dehydrated and dry skin and includes vitamins from the B group, including biotin, folic acid, cyaonocobalamin, niacinamide, panthenol, pyrodixin, riboflavin, Thiamine and mixtures thereof. Dehydrated and dry skin is abnormally dry skin. This circumstance can be related to dry climates, wintry climates, serious vitamin deficiencies, excessive exposure to light or medication. The skin loses moisture and is unable to hold the right amount of water. It can be flaky and irritated, making it itchy. Frequent washing, especially with soap, can contribute to drying out the skin. The B group vitamins used, such as B1, B2, B3, B5, B6, B8, B9, B12 and their mixtures, are particularly suitable to treat dehydrated skin because of their highly nourishing and moisturizing properties, as they help rebuild the Support the lipid coat of the skin and the natural moisturizing factor.

Cosmetic preparation 9

The ninth cosmetic preparation has a mattifying and refining effect, is suitable for treating the skin with sebum and enlarged pores and comprises vitamin H and azelaic acid. Sebum and enlarged pores are the characteristics of oily or combination skin. Excessive sebum secretion is a constitutional characteristic and cannot be completely eliminated, but it can be controlled to bring it back into balance. The skin is shiny and the pores, especially in the T-zone (forehead, nose, and chin), are dilated and in some cases clogged, creating blackheads and pimples. Vitamin H and azelaic acid are two particularly indicated molecules to control the excessive sebum production of the skin and exert a gentle disinfecting and antiseptic effect for an astringent, mattifying and refining effect. Vitamin H (biotin) in particular has a sebum-regulating effect. Azelaic acid has a balancing effect on sebum secretion and at the same time has an antibacterial effect.

Cosmetic preparation 10

The tenth preparation has a dehydrating and depigmenting effect, is suitable for treating bags under the eyes and dark circles and comprises an extract from Centella asiatica and hesperidin. Centella asiatica extract is produced using traditional techniques. The area around the eyes can be affected by some problems, such as puffy eyelids (especially the lower part) and dark circles called "dark circles" that often coexist. In the first case, the swelling that forms the bags under the eyes is due to a poor ability of the skin tissue and lymphatic vessels around and under the eyes to clear the toxin-rich fluids, which causes an unsightly and annoying back pressure. The dark shadows are related to excessive pigmentation caused by reduced exchange at the level of the blood vessels due to a blockage of the blood circulation in the infraorbital region and an accumulation of melanin in the superficial dermis, which remains deposited for a long time. Centella asiatica and hesperidin have strong dehydrating, decongestant and depigmenting properties and must be used with the indicated base for application to the eye area.

As an example, the ten cosmetic preparations of component 1 are given below with the respective percentages of penetration.

1 folds and micro-relief Ingredient 1 7 growth factors 2 Deep folds and furrows Ingredient 2 3 collagens, relaxing peptide 3 relaxation of the skin Ingredient 3 2 elastins, densifying peptide 4 mature skin Ingredient 4 Omega 3-6-9 5 sallow skin Ingredient 5 Vitamin C, shimmering peptide 6 blotchy skin Ingredient 6 Kojic acid, glycolic acid 7 Couperose or irritated skin Ingredient 7 Panthenol and bisabolol 8 Dehydrated and dry skin Ingredient 8 B group vitamins 9 sebum and enlarged pores Ingredient 9 Vitamin H, azelaic acid 10 bags under the eyes and dark circles Ingredient 10 Centella asiatica, hesperidin

Second component of the process / system

The second component of the method and system according to the invention consists of several cosmetic bases which act as carriers of the cosmetic preparations of components 1 and 2 of the system according to the invention. The term base is to be understood as meaning a cosmetically acceptable carrier which can be mixed with one or more of the cosmetic preparations or cosmetically active principles described here.

The cosmetic bases or cosmetically acceptable carriers contain at least one fatty substance or one fatty substance for cosmetic use. The fatty substance is contained in decreasing amounts from base 1 to base 4.

According to some embodiments, the cosmetic bases are the following 4 bases: base 1 (rich in fatty substance) emulsion soft and velvety base 2 (light base, less rich in fats than base 1) emulsion moisturizing, silky base 3 (light or fresh base, less rich in fats than the base 2) Oil-Free Emulsion Fresh, without oils Base 4 (light or delicate base, less rich in fats than the base 3) Eye and Lip Emulsion Eye and lip contour

The cosmetic bases typically contain water and fats, for example triglycerides, fatty acids and oils, and are preferably oil-in-water emulsions or water-in-oil emulsions.

The following is a detailed description of the properties of the four bases.

Base 1

The first base contains fats, has a softening and emollient effect and has special application in the treatment of dry and very dry skin. Typically, this base contains a fatty substance as a carrier and conveniently contains emollient and nourishing substances with moisturizing, soothing and elasticizing properties, such as shea oil, pink mosqueta oil, sweet almond oil and wheat germ oil. Preferably it is in the form of an emulsion, typically water in oil, and contains an emulsifier.

Base 2

The second base is defined as light, since it has a lower fat content and a moisturizing and silky-making effect compared to base 1 and is used on normal and combination skin. Typically it is a light, moisturizing and silky emulsion to be used as a base to mix the previously selected ingredients. It contains, for example, wheat germ oil, which provides moisture and protection, avocado oil, which has excellent skin-friendly and sebum-like properties, hydrolyzed silk proteins which are able to bind water and have a moisturizing effect, whereby they form a thin and invisible film of the skin.

Base 3

The third base is low in fat or fatty acids and is preferably oil-free; it is indicated for the treatment of combination skin and oily skin. The non-oily, fresh and soft texture absorbs excess sebum and allows the grain of the skin to shine through and appear finer. Blemishes are minimized and the shiny areas are visibly matted. The base preferably contains urea, which not only contributes to the moisture content of the skin, but also promotes the detachment of dead cells from the skin surface and leads to soft and smooth skin. It can be an emulsion. For example, it is a base with a fat content below 30% by weight.

Base 4

The fourth base is an emulsion (oil in water or water in oil) and is indicated for the treatment of the eye area and lips. It preferably contains rice oil with an antioxidant effect and restores the natural hydration of the skin; Shea butter has a strong nourishing effect and leaves the skin looking smooth and firm.

The choice of one of the four different cosmetic bases is made depending on the type of skin or the desired texture in relation to the season or the time of application (morning / evening). The fourth base finds specific indication in the formulation of a composition for the treatment of the eye area.

Each of the cosmetic bases used preferably contains a system for increasing the penetration of the cosmetic substances through the epidermis and comprises a mixture of the following three penetration enhancers: decylene glycol, pentylene glycol and caprylic glycol. This system is also referred to in the present invention as transdermal technology, which is the subject of Swiss patent CH 711 466 in the name of the same applicant.

Third, optional component of the process / system

According to some embodiments, the method / system according to the invention comprises a further component which comprises cosmetic preparations.

In one embodiment, this third component of the system according to the invention consists of five cosmetic preparations which have the following formulations.

Optional cosmetic preparation 1

The first cosmetic preparation has a filling effect and comprises, as cosmetically active principles, hyaluronic acid, preferably selected from sodium hyaluronate 0.8K Da, hyaluronic acid Ik Da, hydrolyzed sodium hyaluronate 5K Da, sodium hyaluronate 20K Da, hydrolyzed hyaluronic acid 50K Da, sodium hyaluronate 80K Da, sodium hyaluronate 80K Da 100K there, especially their mix.

The hyaluronic acids used exert a moisturizing effect on the skin. The combination of 7 different types of hyaluronic acids with differentiated molecular weights has a plumping and trophic effect in the different layers of the skin, from the most superficial to the deepest. This extra component can be used, for example, by combining it as additional support with the customizable treatments against wrinkles and sagging skin.

Optional cosmetic preparation 2

The second (extra) cosmetic preparation has a structuring effect on the skin and comprises amino acids, typically arginine, aspartic acid, glycine, alanine, serine, valine, proline, threonine, tryptophan, isoleucine, histidine, phenylalanain, glutamic acid, Glutamine, leucine, lysine, methionine, cysteine, taurine, tyrosine and preferably a mixture thereof are selected. The 20 selected amino acids contribute to the formation of the proteins of the structural fibers of the dermis: collagen, elastin and many other substances that fill the layers of the skin and allow skin to be kept healthy and glowing.

Optional cosmetic preparation 3

The third cosmetic preparation has a cell-renewing effect on the skin and comprises retinyl palmitate or vitamin A. This active ingredient stimulates skin regeneration and causes the keratinocytes of the basal layer located between the epidermis and dermis to differentiate into mature cells that form into the epidermal layers rise and renew the skin. Vitamin A is particularly useful in treating wrinkles and signs of aging. In addition, vitamin A has a synergetic effect when it is combined with the growth factors, the 2 collagens and relaxing peptide (elastin and thickening peptide) omega-3-6-9 acids, vitamin H and azelaic acid.

Optional cosmetic preparation 4

The fourth (extra) cosmetic preparation has an antioxidant effect on the cells and comprises tocopheryl acetate and resveratrol. Vitamin E has an antioxidant effect and protects you from the damage caused by free radicals. Resveratrol also has an anti-oxidative effect on the cells and is particularly used in the case of skin aging due to atmospheric and environmental pollution. Vitamin E and resveratrol work synergistically to provide the skin with a complete detoxifying free radical treatment.

Optional cosmetic preparation 5

The fifth (extra) cosmetic preparation has a remineralizing effect on the skin and comprises minerals which are preferably selected from calcium chloride, iron chloride, manganese chloride, magnesium chloride, copper chloride, zinc chloride, preferably a mixture thereof. Their presence rebalances the amount of minerals lost, for example through heavy sweating after physical activity, long sunbathing or drastic diets.

As an example, the formulations of the five preparations of the third component of the system according to the invention are given in the tables below.

Plumping effect Extra help 7 hyaluronic acids Restorative effect on the skin Extra help 20 amino acids Renewing effect on the skin Extra help Vitamin A Antioxidant, detoxifying Extra help Vitamin A and Resveratrol Remineralization of the skin Extra help 6 minerals

According to some aspects, the cosmetic preparations and / or cosmetic bases used in the process according to the invention can contain penetration enhancers, as described in Swiss Patent No. CH 711 466 in the name of the same applicant, and therefore benefit from the applicant's transdermal technology.

According to one aspect, the invention relates to a method for a cosmetic treatment which comprises mixing one or more drops of the preparation with a cosmetic base in a bowl made of Teflon / glass / polypropylene using a small spatula made of glass / plastics / Teflon .

The container for the cosmetic preparations is preferably a vial made of dark glass for optimal preservation of the active ingredients, which is provided with a dropper with which the desired amount (1-3 drops) of the cosmetic preparation is taken.

The cosmetic preparation containing the active ingredients is removed and metered using the glass dropper.

With the small spatula, the drops of the cosmetic preparation are mixed with the base in the bowl until a homogeneous composition is obtained, which is applied to the affected zone / area, for example in the face and / or neck region . To treat the eye area and lips, it is possible to use a dose of cream and a drop or two of the cosmetically active ingredient.

According to one embodiment, the cosmetic method according to the invention provides the following three steps: Step 1: Determination of the problem and selection of the vial which contains the suitable cosmetic preparation. Up to three compositions, including any extra compositions, can be combined with a single cosmetic base. Step 2: Selection of the base without active ingredients in a dispenser depending on the desired texture (rich, light, oil-free, eye-lips), whereby the base in the case of the face contains the active ingredients for up to three different problems and in the case of the eye- Lips area for up to two problems. Step 3: Just before application, mix the active ingredients with the base with the enclosed bowl and spatula and apply immediately afterwards; every day for 4 weeks.

The molecular weights of the cosmetically active ingredients in polymeric form or cosmetically active polymeric substances which are described in the present application, such as, for example, hyaluronic acids, are typically given as weight-average molar mass (MW) (Da). The weight average molecular weight of the cosmetic substances mentioned in the application can be determined using standard methods customary in the sector, such as those described in Ueno et al., 1988, Chem Pharm Bull. 36, 4971-4975; Wyatt 1993, Anal Chim Acta 272: 1-40; Watt Technologies 1999 "Light scattering University Dawn Course Manual and" Dawn Eos Manual "Wyatt Technology Corp. Santa Barbara CA (USA) are shown.

In some embodiments, the mixtures of the cosmetic preparation and the cosmetic base can contain at least 0.0001% and preferably from 0.1 to 20% by weight, from 0.5 to 5% by weight of each cosmetically active or effective ingredient.

The term “cosmetically acceptable” as used here means that the dermocosmetic composition or its active components are suitable for application to the skin in general and after application no unwanted toxicity, allergic reaction, redness, incompatibility Cause instability and similar reactions. The term dermocosmetic essentially means cosmetic, related to the skin.

In the scope of the present invention, the term “carrier” relates to a carrier, carrier, diluent or auxiliary which can be present in the composition according to the invention. Any carrier and / or carrier which is suitable for the desired preparation form for administration is taken into account in the uses described here.

In the field of the invention, the term “cosmetic bases” is understood to mean cosmetically acceptable carriers which are suitable for introducing the cosmetically active principles contained in the cosmetic preparations.

The term cosmetic preparations is understood to mean compositions which contain cosmetically active principles which are to be added to the cosmetic bases and / or mixed therewith.

The inventive method and / or system enables the person in need of treatment to select at least one cosmetic preparation suitable for their aesthetic requirements from component 1 and to combine it with a cosmetic base of component 2 and optionally one or more of the optional cosmetic preparations of Add component 3.

By combining the various cosmetic preparations and bases of the three components of the system according to the invention, it is possible, for example, to obtain up to 2,300 possible treatments, whereby a high degree of personalization of the cosmetic treatment is achieved.

This possibility is shown by the following table, in which the possible combinations with a system with 10 cosmetic preparations (component 1), 4 bases (component 2) and 5 further cosmetic preparations (component 3) are listed. 1 Cosmetic preparation 15 45 60 2 Cosmetic preparation 105 315 420 3 Cosmetic preparation 455 1,365 1,820 Total number of options 575 1,725 2,300

According to some aspects of the invention, the implementation of the method according to the invention provides a phase in which a suitable cosmetic preparation is selected from 15 available preparations, each of which is contained in a container, with between one and three drops of the cosmetic from the container Preparation are removed and then a cosmetic base is selected from four available bases and this adds the previously removed drops of the cosmetic treatment and mixed therewith in order to form a ready-to-use composition.

For example, a cosmetic preparation contained in a vial is selected and three drops of the preparation are removed from the vial with a dosing pipette and added to one of the available bases, which is taken from suitable containers. If it is decided to use two cosmetic preparations, it is possible to add three drops of each preparation, a total of six drops, to the cosmetic base.

When three cosmetic preparations are selected, the number of drops added to the base is two drops of each, a total of six drops.

The applicant has also created an information graphic to represent the system and / or method according to the invention, which is explained in the accompanying figure.

The following examples are provided for illustrative purposes of the present invention.

EXAMPLES

EXAMPLE 1

Dosage scheme of embodiments of the cosmetic method according to the invention Dosage in the case of the selection of 1 active ingredient for the facial treatment • 2 withdrawals of the base cream They correspond to 0.23 ml of product per withdrawal for a total volume of the base cream of 0.46 ml. • 3 drops of the Cosmetically active ingredient dosage in the case of selecting 2 active ingredients for the facial treatment • 2 withdrawals of the base cream. They correspond to 0.23 ml of product per withdrawal for a total volume of the base cream of 0.46 ml. • 3 drops of each active ingredient dosage in the case of Choice of 3 active ingredients for the facial treatment • 2 withdrawals of the base cream. They correspond to 0.23 ml of product per withdrawal for a total volume of the base cream of 0.46 ml. • 2 drops of each active ingredient dosage in the case of selecting 1 or 2 active ingredients Ingredients for the treatment of eyes and lips • 1 removal of the base cream you corresponds to 0.23 ml of product per withdrawal for a total volume of the base cream of 0.46 ml. • 1 drop of each active ingredient

EXAMPLE 2

Embodiments of the cosmetic method

Blemish to be treated

Skin marked by expression lines and slackening and pale in color

Cosmetic treatment

3 collagens with a wrinkle-filling effect and acetyloctapeptide-3 for smoothing expression lines Dosage = 2 drops per application. + 2 elastins and acetyltetrapeptide-2, which work synergistically for a double lifting effect and firming. Dosage = 2 drops per application. + Vitamin A, which has an efficient renewal effect on the layers of the epidermis. Dosage = 2 drops per application. Treatment with a silky, moisturizing emulsion for sensitive skin

Blemish to be treated

Very dry, dehydrated and devitalized skin

Cosmetic treatment

8 vitamins of the B group for an intensive moisturizing and nourishing effect Dosage = 2 drops per application. + Omega 3-6-9 with strong rebuilding and anti-aging effects Dosage = 2 drops per application. + 6 minerals that are suitable for restoring adequate remineralization of the skin. Dosage = 2 drops per application. Treatment with a rich, softening and velvety emulsion for dry and very dry skin

Blemish to be treated

Sallow, dull, and greyish skin

Cosmetic treatment

Vitamin C and oligopeptide-68 with a lightening and shimmering effect Dosage = 3 drops per application. Treatment with a silky, moisturizing emulsion for sensitive skin

Blemish to be treated

Facial skin with first wrinkles and an oily skin surface

Cosmetic treatment

7 growth factors to stimulate skin regeneration with the resulting smoothing of the skin Dosage = 3 drops per application. + Vitamin H and azelaic acid, which have a sebum-regulating and balancing effect on the skin surface. Dosage = 3 drops per application. Treatment with a light, oil-free emulsion

Blemish to be treated

Wrinkled eye area with crow's feet, bags under the eyes and tired skin

Cosmetic treatment

Depending on the depth of the wrinkles in the area to be treated, there is a choice between: 7 growth factors to stimulate skin regeneration with resulting smoothing of the skin or 3 collagens with a wrinkle-filling effect and acetyloctapeptide-3 to smooth expression lines Dosage = 1 drop per Use. + Extract from Centella asiatica and hesperidin for an intensive dehydrating effect on fluid accumulations in the area around the eyes Dosage = 1 drop per application. Treatment with a delicate emulsion specially formulated for the eye area and lips.

EXAMPLE 3

Procedure for the treatment of pale, dull and greyish skin

Phase 1 (selection of the active ingredient)

Ingredient 5. Contains Vitamin C and Oligopeptide-68 with brightening and shimmering effects. Dosage = 3 drops per application.

Phase 2 mixing with the cosmetic base

Basis L Light - treatment with a silky, moisturizing emulsion for sensitive skin = dose 2 withdrawals per application on the bowl and add 3 drops of ingredient 5.

EXAMPLE 4

Method for the treatment of dry, moist facial skin

Phase 1 (selection of the cosmetically active ingredient)

Ingredient 8. Contains 8 vitamins of the B group for an intensive moisturizing and nourishing effect. Dosage = 2 drops per application.

Ingredient 4. Contains Omega 3-6-9 with powerful rebuilding and anti-aging effects. Dosage = 2 drops per application.

Ingredients EH 6 Minerals that are suitable for restoring adequate remineralization of the skin. Dosage = 2 drops per application.

Phase 2 mixing with the cosmetic base

Mixing the selected ingredients with Basis R Rich - rich, emollient and velvety = dose 2 withdrawals per application on the bowl and add 2 drops of each ingredient (6 drops in total).

EXAMPLE 5

Method of treating the skin of the face with the first wrinkles and oily surface of the skin

Phase 1 (selection of the cosmetically active ingredient)

Ingredient 1. Contains 7 growth factors to stimulate skin regeneration with the resulting smoothing of the skin. Dosage = 3 drops per application.

Ingredient 9. Contains vitamin H and azelaic acid, which have a sebum-regulating and balancing effect on the surface of the skin. Dosage = 3 drops per application.

Phase II mixing with the cosmetic base

Treatment with the base O Oil-Free - fresh emulsion without oils = dose 2 withdrawals per application on the bowl and add 3 drops of each ingredient (6 drops in total).

EXAMPLE 6

Method for the treatment of facial skin marked by expression lines and slackening with pale color

Phase I.

Ingredient 2. Contains 3 collagens with wrinkle-filling properties and acetyloctapeptide-3 for smoothing expression lines. Dosage = 2 drops per application.

Ingredient 3. Contains 2 elastins and acetyltetrapeptide-2, which act synergistically for a double lifting effect and firming. Dosage = 2 drops per application.

Ingredients EH Vit. A with high vitamin A concentration (has a strongly renewing effect on the layers of the epidermis) = 2 drops per application.

Phase II

Mix with fatty base

EXAMPLE 7

Method of treating wrinkled eye area with crow's feet, bags under the eyes and sagging skin

Phase I.

Ingredient 1 or 2 with a strong anti-wrinkle effect, to be selected depending on the depth of the wrinkles in the area to be treated. Dosage = 1 drop per application.

Ingredient 10 with extract from Centella asiatica and hesperidin for an intensive dehydrating effect on fluid accumulations in the area around the eyes. Dosage = 1 drop per application.

Treatment with the base eyes / lips

Phase II

Mixing with a delicate oil-in-water emulsion that is specifically formulated for the eye area = dose 1 withdrawal per application on the bowl and add the drop of each ingredient (2 drops in total).

EXAMPLE 8

Formulation of a cosmetic preparation (component 1 of the system) which contains 7 growth factors. WATER q.b. 100 SH-POLYPEPTIDE-93 0.000001-10 SH-OLIGOPEPTIDE-1 0.000001-10 SH-OLIGOPEPTIDE-2 0.000001-10 SH-POLYPEPTIDE-11 0.000001-10 SH-POLYPEPTIDE-3 0.000005 SH -POLYPEPTIDE-5 0.000005 SH-POLYPEPTIDE-8 0.000005 TETRASODIUM EDTA 0.1-1 GLYCERIN 0.01-1 CARBOMER 0., 1-10 SODIUM HYDROXIDE qb PRESERVATIVES q.b. GLYCINE SOJA OIL 0.001-1 SODIUM OLEATE 0.001-1 POLYSORBATE 60 0.0001-1 POLYSORBATE 20 0.0001-1 LECITHIN 0.0001-1 PENTYLENE GLYCOL 0.0001-1 CAPRYLYL GLYCOL 0.0001-1 DECYLENE GLYCOL 0.0001 -1

EXAMPLE 9

Formulation of a cosmetic preparation (component 1 of the system) containing KOJIC ACID and GLYCOLIC ACID and three penetration enhancers. WATER qb 100 SODIUM HYDROXIDE q.b. PRESERVATIVE q.b. TETRASODIUM EDTA 0.1-1 CHONDRUS CRISPUS EXTRACT 0.1-1.0 XANTHAN GUM 0.1-1.0 KOJIC ACID 0.01-10 GLYCOLIC ACID 0.1-20 PENTYLENE GLYCOL 0.0001-1 DECYLENE GLYCOL 0 , 0001-1 CAPRYLYL GLYCOL 0.0001-1

EXAMPLE 10

Formulation of a high-fat cosmetic base containing three penetration enhancers of the cosmetically active principles. WATER qb 100 DIISOPROPYL DIMER DILINOLEATE 1-10 HYDROGENATED POLYDECENE 1-10 ISOSTEARYL ISOSTEARATE 1-10 TRITICUM VULGARE GERM OIL 1-10 COCO-CAPRYLATE 1-10 COCONUT ALKANES 1-10 BUTYROSPERMUM PARKII BUTTER 0.1-10- GLOBE BUTTER 0.1-10 10 CETEARYL ALCOHOL 0.5-5 GLYCERYL STEARATE 0.5-5 SODIUM LAUROYL GLUTAMATE 0.01-5 STEARIC ACID 0.1-5 ACRYLATES / C10-30 ALKYL ACRYLATE CROSSPOLYMER 0.1-5 PRUNUS AMYGDALUS DULCIS OIL 0.1-10 ROSA MOSCHATA SEED OIL 0.1-10 TOCOPHERATE SEED OIL 0.1-10 , 01-5 PENTYLENE GLYCOL 0.0001-1 DECYLENE GLYCOL 0.0001-1 CAPRYLYL GLYCOL 0.0001-1 COCO-CAPRYLATE / CAPRATE 0.1-5 CAPRYLYL GLYCOL 0.1-5 XANTHAN GUM 0.1-1 DISODIUM EDTA 0 ,1

Claims (11)

1.System or kit for the treatment of one or more blemishes or cosmetic problems of the skin of a person, comprising at least two components a) and b): a) a first component comprises the following ten cosmetic preparations, each of which is suitable for treating a specific skin problem: a cosmetic preparation 1 which contains seven growth factors with anti-wrinkle and skin-regenerating effects a cosmetic preparation 2 which contains collagen with a smoothing effect, a peptide with a relaxing effect a cosmetic preparation 3 containing elastin, a skin-compacting peptide a cosmetic preparation 4 containing polyunsaturated fatty acids selected from omega 3, omega 6, omega 9 and their mixtures a cosmetic preparation 5 which contains vitamin C and / or oligopeptide-68 or TGF-β1 biomimetic a cosmetic preparation 6 containing kojic acid and / or glycolic acid a cosmetic preparation 7 containing panthenol and / or bisabolol a cosmetic preparation 8 which contains vitamins of the B group selected from B1, B2, B3, B5, B6, B8, B9, B12, and mixtures thereof a cosmetic preparation 9 which contains vitamin H and / or azelaic acid a cosmetic preparation 10 which contains a plant extract of Centella asiatica and / or hesperidin b) a second component, which comprises the following 4 cosmetic carriers / bases which are intended to be mixed with the cosmetic preparations. Base 1, which contains rich emulsion or a water-in-oil emulsion with a softening and emollient effect Base 2, which contains Light Emulsion or a moisturizing water-in-oil emulsion Base 3, which contains Oil-Free Emulsion Base 4, which contains Eye and Lip Emulsion 2. System or set according to claim 1, which comprises a third component c) which comprises the following 5 cosmetic preparations a cosmetic preparation containing 7 hyaluronic acids a cosmetic preparation containing 20 amino acids a cosmetic preparation containing vitamin A. a cosmetic preparation containing vitamin E and / or resveratrol a cosmetic preparation that contains 6 minerals 3. System or set according to claim 1, wherein In cosmetic preparation 1, the seven growth factors with anti-wrinkle and skin-regenerating effects are: - Synthetic human acidic fibroblast growth factor or Sh polypeptide-11 - Synthetic human basic fibroblast growth factor or Sh polypeptide-1 - Synthetic human keratinocyte growth factor or Sh polypeptide-3 - Synthetic human insulin like 1 growth factor or Sh-oligopeptide-2 - Synthetic Human Platelet Derived Growth Factor or Sh-Polypeptide-8 - Synthetic Human Connective Tissue Growth Factor or Sh-Polypeptide-93 - Synthetic Human Transforming Growth Factor Beta3 or Sh Polypeptide-5 In cosmetic preparation 2, the collagen with a smoothing effect is a mixture of hydrolyzed collagen with an average molecular weight of 2K Da, hydrolyzed collagen with an average molecular weight of 12H Da, soluble collagen with an average molecular weight of 300K Da and the peptide with a relaxing effect acetyl octapeptide Is -3; in the cosmetic preparation 3, the elastin comprises hydrolyzed elastin with a molecular weight of 1.4 K Da and hydrolyzed elastin with a molecular weight of 2.2 K Da; the densifying peptide is acetyltetrapeptide-2 with the formula Ac-Lys-Asp-Val-Tyr-OH. 4. System according to any one of claims 1-3, wherein in the second component b) the base 1 is based on fatty substance or substances base 1 is an oil-in-water emulsion containing wheat germ oil base 3 is a base with a lower fat content than base 1 is base 4 is an emulsion containing rice oil. 5. System or set according to claim 2, in which the 7 hyaluronic acids of the cosmetic preparation are sodium hyaluronate 0.8K Da, hyaluronic acid 1k Da, hydrolyzed sodium hyaluronate 5K Da, sodium hyaluronate 20K Da, hydrolyzed hyaluronic acid 50K Da, sodium hyaluronate 80K Da, sodium hyaluronate 100K Da and mixtures thereof include. 6. System or set according to claim 2, in which the 20 amino acids from arginine, aspartic acid, glycine, alanine, serine, valine, proline, threonine, tryptophan, isoleucine, histidine, phenylalanain, glutamic acid, glutamine, leucine, lysine, methionine, cysteine , Taurine, tyrosine and their mixture are selected. 7. System or set according to claim 2, wherein the 6 minerals are calcium chloride, iron chloride, manganese chloride, magnesium chloride, copper chloride and zinc chloride. 8. System or set according to any one of claims 1-4, in which the cosmetic preparations and / or the cosmetic bases comprise a penetration enhancer which is selected from decylene glycol, pentylene glycol and caprylic glycol and mixtures thereof. 9. System or set according to any one of claims 1-8, comprising a spatula and a disc-shaped container for mixing the cosmetic preparations. 10. A personalized dermo-aesthetic system or kit according to any one of claims 1-9 for treating multiple cosmetic skin problems in a single treatment comprising: a first component a) which comprises the cosmetic preparations 1-10 with the following cosmetic indications 1 folds and micro-relief Ingredient 1 7 growth factors 2 Deep folds and furrows Ingredient 2 3 collagens, relaxing peptide 3 relaxation of the skin Ingredient 3 2 elastins, densifying peptide 4 mature skin Ingredient 4 Omega 3-6-9 5 sallow skin Ingredient 5 Vitamin C, shimmering peptide 6 blotchy skin Ingredient 6 Kojic acid, glycolic acid 7 Couperose or irritated skin Ingredient 7 Panthenol and bisabolol 8 Dehydrated and dry skin Ingredient 8 B group vitamins 9 sebum and enlarged pores Ingredient 9 Vitamin H, azelaic acid 10 bags under the eyes and dark circles Ingredient 10 Centella asiatica, hesperidin a second component b), which comprises the following bases 1-4, in which one or more of the cosmetic preparations of components a) and c) are dispersed. Base 1 emulsion, the fatty substance Base 2 emulsion, which contains less fatty substance than Base 1 Base 3 Oil-Free Emulsion Base 4 Eye and Lip Emulsion and optionally a third component c), which contains five cosmetic preparations with the following cosmetic indications: Plumping effect Extra help 7 hyaluronic acids Restorative effect on the skin Extra help 20 amino acids 11. A method of dermocosmetic treatment to treat one or more cosmetic skin problems in a single treatment, comprising the following phases: a) Creation of several cosmetic preparations, preferably 10, each of which contains mixtures of cosmetically active principles, and several cosmetic bases, preferably 4, in order to infiltrate the cosmetic compositions. b) Selecting one or more cosmetic preparations from several available cosmetic preparations depending on the type of skin blemish to be treated and mixing one or more selected preparations with a cosmetic base in order to form a cosmetic composition, c) Applying a cosmetically effective amount of the cosmetic composition prepared in phase b) to the skin of the person in need of treatment.