CH706750A2 - Method for the intravenous injection of isotonic-physiological electrolysis water to combat systematic viroses and bacteriosis by means of oxidative radicals. - Google Patents

Abstract

Method for the intravenous injection of isotonic-physiological electrolysis water for controlling systemic viruses and bacterioses by means of oxidative radicals, characterized in that the oxidative radicals such as hypochlorite, hypochlorite acid, ozone, hydrogen peroxide, mineral peroxides, oxygen and hydrogen, even in multidrug-resistant viruses and bacteria Compared to conventional antivirals and bactericides, show a good effect and also produce no resistance to viruses, bacteria, fungi and yeasts in cells and in the blood because of their high oxidation potential. The new infusion process demonstrates that, with the help of novel water electrolysis technology using isotonic-physiological electrolysis water, which has a pH of 7.34 and a maximum salt concentration (NaCl, KCl) of 0.9%, an osmolarity of 308 mosmol / l and an osmotic pressure of 7.6 bar, resistant viruses and bacteria can be eliminated intravenously.

Description

State of the art

So far, antivirals, antibiotics and other drugs such as acetylsalicylic acid, ibuprofen and para-acetylamino-phenol, etc. containing were used for the treatment of systemic viruses and bacteriosis. It is found that most antivirals have very large harmful side effects and also lead to multi-resistances and transmutases in viruses, which can have very dangerous effects with regard to pandemics and can no longer be brought under control even with vaccinations [cf. HIV, bird flu (virus H5N1 virus), swine flu virus (influenza A virus H1N1))]

In the case of bacteriosis, traditional antibiotics often no longer work today, since pathogenic bacterial germs have also built up a multi-resistance and are no longer effective due to the widespread and intensive use of antibiotics. For example with EHEC (enterohaemorrhagic Escherichia coli), listeria, salmonella and streptococci. In Germany alone, over 700,000 patients return home with a secondary infection contaminated in the hospital, and over 15,000 of them die from it! Truly a monstrous scenario! Multi-resistant germs that can no longer be cured with antibiotics represent a true global threat to humanity and are a “medical time bomb” that many scientists have been drawing attention to for a long time!

Technical area

The new invention is to show that with the help of the new water electrolysis technology using electrolyzed neutral electrolysis water (pH 7.34), made with boron-doped diamond electrodes or other chemically stable, metallic electrodes, with an electrical Overpotential of 2-4 volts, and with the addition of salts (NaCl, KCl etc.) a new method was developed which can be used for intravenous injection of isotonic-physiological electrolysis water to combat systemic viroses and bacterioses by means of oxidative radicals.

Presentation of the invention

introduction

Electrolytically produced, oxidative water (EOW)

Electrolytically oxidative water (EOW) or chemically active water destroys microorganisms such as viruses, bacteria, fungi, yeasts and protozoa by oxidative radicals not chemically, but physically. Because of its high oxidative reduction potential (ORP), “active water” damages the cell wall membranes of pathogens. The pathogen is compromised, which leads to an osmotic or hydrogen overload inside the cell. The damaged cell membranes allow an increased water transfer between the cell membranes, which leads to a hydrogen flooding of the cells, and these are filled faster than the cells can get rid of the water. This fact leads to the bursting of the bacterial cells or envelope membranes, or to cell death due to a pressure explosion in a few seconds. Since it is a physical principle of destruction, there is no evidence of resistance to pathogens. At the same time, the water molecule clusters that make up water are electrochemically split from 14 to 18 in certain cases up to 60 molecules per cluster into 3 molecules, which leads to a 3-4-fold improvement in cell membrane resorption.

Principle of electrolysis: Example of electrolysis with a zinc iodide solution (any electrode material): If you connect two metal plates (electrodes) or boron doped diamond electrodes, each with a cable and a device that generates direct current, e.g. a battery or a rectifier - and transfers these platelets into a beaker with an aqueous solution (any ions) and now applies a voltage, a substance is formed on both metal platelets, the ions of which are present in the solution. The voltage source causes a lack of electrons in the electrode connected to the positive pole (anode) and an excess of electrons in the other electrode connected to the negative pole (cathode). The aqueous solution between the cathode and anode contains electrolytes, which are positively or negatively charged ions.

The positively charged cations in an electrolysis cell migrate to the negatively charged cathode when a voltage is applied (attraction of opposing charges). They pick up one or more electrons at the cathode and are thereby reduced. The opposite process takes place at the anode. There, the negatively charged anions give off electrons, which means they are oxidized. The number of electrons consumed by the reduction at the cathode corresponds to the electrons taken up by the anode. The electrolysis of aqueous saline solution produces the same volume of hydrogen gas as chlorine gas. The electrolysis of water produces twice as much hydrogen gas as oxygen gas, since the two positively charged protons of a water molecule migrate to the cathode and there each have to take up an electron so that hydrogen is formed, while the doubly negatively charged oxygen anion at the anode releases two electrons must in order to connect to the oxygen molecule. The minimum voltage that must be applied for electrolysis is referred to as the deposition potential, while electrolysis of water or aqueous salt solutions is also referred to as the decomposition voltage. This voltage (or a higher voltage) must be applied in order for the electrolysis to take place at all. For every substance, for every conversion of ions to two or more atomic molecules, the decomposition voltage and the deposition potential can be determined using the redox potential. The redox potential provides many other important information for electrolysis, for example for the electrolytic decomposition of metal electrodes in acid or for reducing the decomposition voltage by changing pH values. For example, the redox potential can be used to calculate that the formation of oxygen at the anode during the electrolysis of water in a basic solution (decomposition voltage: 0.401 V) occurs at a lower voltage than in acidic (decomposition voltage: 1.23 V) or neutral ( Decomposition voltage: 0.815 V) solution, on the other hand hydrogen forms more easily at the cathode under acidic conditions than under neutral or basic conditions). If there are several reducible cations in an electrolyte solution, then after the redox series, the cations on the cathode are reduced that have a more positive (weaker negative) potential in the redox series (voltage series), which corresponds to the 0 potential of the proton Hydrogen electrode voltage come as close as possible. During the electrolysis of an aqueous ion-containing solution, hydrogen is normally formed at the cathode.Also when there are several types of anions that can be oxidized, those that are in the redox series as close as possible to voltage zero, i.e. a weaker positive redox- Have potential. Normally, the electrolysis of aqueous NaCl at the anode produces oxygen and not chlorine. After the decomposition voltage is exceeded, the current strength increases proportionally with the increase in voltage. According to Faraday, the amount by weight of an electrolytically formed substance is proportional to the amount of current that has flowed (current strength multiplied by time). For the formation of 1 g of hydrogen (approx. 11.2 liters, two electrons are required to form a hydrogen molecule) from aqueous solution, an amount of current of 96485 C (As) = 1 Faraday is required. With a current of 1 A between the electrodes, the formation of 11.2 liters of hydrogen takes 26 hours and 48 minutes. In addition to the redox potential, the overvoltage (overpotential) is also important. Due to kinetic inhibitions on electrodes, a significantly higher voltage is often required than can be calculated from the calculation of the redox potential. Depending on the material properties of the electrodes, the overvoltage effects can also change the redox series, so that other ions are oxidized or reduced than would have been expected based on the redox potential. Shortly after the electrolysis has been switched off, an ammeter can be used to detect a current surge in the other direction. In this short phase, the reverse process of electrolysis, the formation of a galvanic cell, begins. In this case, electricity is not used for the implementation, but electricity is generated for a short time; this principle is used in fuel cells. If you force a separation of individual molecules or bonds through electrolysis, a galvanic element acts at the same time, the voltage of which counteracts the electrolysis. This voltage is also known as the polarization voltage.

As an additional effect in the water electrolysis process, the water molecule clusters are electrochemically cut down from 14-18 molecules to 2-3 molecules per cluster by the production of OH-hydroxide ions on the surface of the electrodes, resulting in a 3–4-fold increase in the dissolving power of water and increases the resorption potential through cell membranes by 2 to 3-fold. In addition, the water becomes slightly alkaline during the electrolysis process. This is understandable, since protons (H +) are converted into H2 (hydrogen) during electrolysis, which means that OH ions remain, which increase the pH value. For this reason, the acid capacity increases from 1.37 mmol / L to 3.42 mmole / L up to pH 4.3.

Electrodes

[0008] There are only a few anode electrodes that remain inside during the electrolysis - that is, they do not go into solution at all. Boron-doped full diamond is the newest material that does not dissolve at all during electrolysis. Inhibition phenomena at the anode, which lead to an overvoltage in the formation of oxygen, are observed above all with full diamond anodes (overvoltage: 3–4 V) and platinum electrodes (1.2 V. With these, the electrolysis of aqueous saline solution produces chlorine instead of oxygen. At zinc and lead overvoltage: 0.78 V) and especially mercury cathodes (0.80 V), hydrogen protons show a considerable overvoltage and the formation of hydrogen only takes place at a much higher voltage. The considerable overvoltage of hydrogen at the mercury cathode, in which the sodium is bound as an amalgam and therefore withdrawn from the equilibrium, is used for the technical production of caustic soda. Due to the considerable overvoltage at this electrode during hydrogen formation, the redox series changes and instead of hydrogen protons, sodium cations now migrate to the mercury cathode.

Electrolysis of water

The electrolysis of water consists of two partial reactions that take place on the two electrodes. The electrodes are immersed in water, which is made slightly conductive by the presence of mineral ions, and oxygen is then obtained. Positively charged hydronium ions (H3O +) migrate in the electrical field to the negatively charged electrode (cathode), where they each take up one electron. This creates hydrogen atoms, which combine with another hydrogen atom created by reduction to form a hydrogen molecule. What remains are water molecules in 2- and 3-molecular cluster form.

[0010] 2 H3O + + 2 e-→ H2 + 2 H2O

The separated, gaseous hydrogen rises at the cathode. The negatively charged hydroxide ions migrate to the positively charged electrode (anode). Each hydroxide ion gives off an electron to the plus pole, so that oxygen atoms are created that combine to form oxygen molecules. The remaining H + ions are immediately neutralized by hydroxide ions to form water molecules.

[0012] 4 OH <-> → O2 + 2 H2O + 4 e <->

Here, too, the separated oxygen rises as a colorless gas at the anode. The overall reaction equation for the electrolysis of water is: 4 H3O <+> + 4 OH <-> → 2 H2 + O2 + 6 H2O

The hydronium and hydroxide ions on the left come from the autoprotolysis of water: 8 H2O <> + 4 H3O <+> + 4 OH <->

[0015] The electrolysis equation can therefore also be written as follows: 8 H2O → 2 H2 + O2 + 6 H2O or after shortening the water: 2 H2O → 2 H2 + O2

Hydroxide ion

The hydroxide ion is a negatively charged ion that is formed when bases react with water. Its chemical formula is OH <->.

A general base B reacts with water according to the following scheme:

The pH of the resulting solution can be determined on the basis of the concentration of the hydroxide ions. To do this, you first calculate the so-called pOH value. pOH = - log c (OH <->)

And from this the pH value: pH = k - pOH

There is a k for each temperature.

[0021] Under normal conditions, k = -14.

[0022] Hydroxide ions are also contained in pure water at 20 ° C. in a concentration of 10-7 mol · I -1. This is related to the autoprotolysis of water according to the following reaction equation:

Admission

Our own early tests and other test results led to the submission of license applications to the FDA (Food and Drug Administration, USA), which issued a general license for electrolysis water in December 2002 and was granted the status "GRAS" (Generally Regarded as Safe ) distinguished.

Electrolyzed oxidative water received FDA (USA Food and Drug Administration), USDA (United Status Department of Agriculture) and EPA (USA Environmental Protection Agency) approval for general applications in the food sector, for food surface disinfection, for Dairy, meat and restaurant technical applications.

The corresponding pages of the FDA and USDA grant numbers read 21 CFR 173, 178, 182, 184 & 198.

The EPA grants and publications page is 40 CFR 180.940 and that of the National Organic Program is 21 CFR 178.1010. In Japan, electrolysis water is approved as a food additive.

With the electrolysis water product HYDROSEPT, the inventor holds the rights to a biocide entry at the Federal Office of Public Health in Bern, Switzerland.

Isotonic saline solution

One 500 ml NaCl infusion bottle

The isotonic saline solution is a solution of saline (sodium chloride) in water iso-osmotic to the blood plasma. It contains 9 g of table salt (sodium chloride) per liter (0.9% m / V) and has an osmolarity of 308 mosmol / l. The isotonic saline solution is inexpensive and the most widely used infusion solution in the world.

composition

The term “physiological saline solution” should not be used because, although the osmolarity is physiological, the concentration of sodium and chloride ions is not. At 154 mmol / l, both ions are significantly more concentrated than in human serum (serum sodium: 135–145 mmol / l; serum chloride: 98–109 mmol / l). This imbalance is necessary because the osmotic effect of the other components contained in human blood (such as other electrolytes, so-called «corpuscular» components such as proteins) must be taken into account.

The sterile and pyrogen-free isotonic saline solution in containers (plastic or glass ampoules or bottles and plastic bags) of two to 30,000 ml (veterinary medicine) is available as a solution for medical use.

application

The isotonic saline solution is used as a carrier solution for drugs or to keep a venous access open in patients. The solution is also used to rinse catheters and wounds, nose or eyes.

When this electrolyte solution is infused, owing to the osmolarity, there is no significant fluid shift between the intracellular and extracellular space. The overloading of the body with sodium and chloride ions leads to an inhibition of the renin-angiotensin-aldosterone system and to a stimulation of the ANF. The lack of other blood plasma electrolytes, particularly hydrogen carbonate, can lead to diluent acidosis. For these reasons, there are only a few indications for using isotonic saline solutions for fluid therapy, since better alternatives are available with fully electrolyte solutions.

infusion

Various infusions and infusion sets

[0033] Infusion, infusion therapy (Latin infusio "Aufguss" and infundere "pour", penetrate ") describes the continuous, mostly parenteral administration of liquids. They are usually administered intravenously.

Certain therapeutic methods usually involve the use of infusions, e.g. Fluid administration, volume replacement or substitution, volume and osmotherapy. The administration of blood components by infusion is known as transfusion.

Outside of pure fluid therapy, infusion solutions are still used in parenteral nutrition and as carrier solutions if a certain administration time should not be exceeded or if certain maximum drug concentrations at the infusion site should not be exceeded (electrolyte therapy, acid-base correction, administration of antibiotics, etc.) .).

Infusion solutions and indications

Various preparations are available for infusion therapy. A distinction can be made between non-specific solutions such as electrolyte solutions ("crystalloids") or glucose solutions from those with a specific therapeutic purpose, e.g. colloidal solutions for volume therapy, highly concentrated glucose solutions and other nutrient solutions for nutritional therapy or buffer solutions for treating disorders of the acid-base balance.

Electrolyte solutions

Electrolyte solutions (“crystalloid solutions”) are used to compensate (in the case of dehydration) or to cover fluid requirements, as part of parenteral nutrition and to compensate for electrolyte disorders. Due to the low oncotic pressure, they only remain in the blood vessels for a short time and are distributed in the extracellular space, which is why they are only suitable to a very limited extent for compensating for large blood losses in hypovolemic shock. Due to the rapid redistribution, there is a risk of cerebral and pulmonary edema if larger amounts are administered.

Isotonic saline solution

The simplest electrolyte solution is the isotonic saline solution, which due to its non-physiological composition is only used as a rinsing and diluting solution. A special indication is hypotonic dehydration.

Full electrolyte solutions

Full electrolyte solutions (VEL) or balanced solutions contain electrolytes (sodium, potassium, calcium, partly magnesium, chloride) in a body-like composition. Since they lack the negatively charged proteins and the hydrogen carbonate of the plasma, organic anions such as acetate, malate or lactate are added as a substitute, which results in isotonicity. According to recent research results, lactate should no longer be used because of its considerable disadvantages. The range of applications for fully electrolyte solutions is wide; they represent the standard of crystalloid solutions.

Special forms are half, 2/3 or 1/3 electrolyte solutions (designation according to the electrolyte content of the full electrolyte solutions), the use of which has largely been abandoned. There are also combination solutions with colloids or glucose.

Colloidal Solutions

Colloidal infusion solutions for use as a volume replacement (plasma replacement) or in volume therapy (plasma expander, “blood thinning” or hemodilution) are characterized by their macromolecule content (carbohydrates such as hydroxyethyl starch or dextrans; proteins such as gelatin or albumin). Since these cannot cross the vessel wall, the colloid-osmotic pressure they increase is maintained until the molecules are eliminated via enzymatic degradation or absorption by the mononuclear phagocytosis system. In addition to a longer retention time in the vascular system compared to electrolytes, this also results in a more pronounced and longer-lasting effect on the blood volume, which is why they are used to compensate for greater volume losses in hypovolemic shock. The improvement in the microcirculation caused by the colloids also has a positive effect in the shock.

Possible side effects are changes in blood clotting (tendency to bleed), anaphylactic reactions and acute kidney failure.

Glucose solutions

Glucose solutions are available in various concentrations. They serve as an energy supplier in the context of an infusion therapy. Since they do not contain electrolytes and spread quickly into the intracellular space ("free water"), there is a risk of cerebral and pulmonary edema if larger amounts are administered. Glucose solutions are also part of total parenteral nutrition.

Osmotherapeutics

Osmotherapeutic agents are hypertonic infusion solutions whose active ingredients (mannitol, glycerine) lead to an increase in the osmotic pressure in the extracellular space and thereby remove water from the surrounding tissue. Areas of application of osmotherapeutic agents are the treatment of edema and the promotion of urine flow to prevent or treat acute kidney dysfunction or to promote the excretion of toxic, urinary substances in the event of poisoning.

administration

Application forms

The intravenous standard application of infusion solutions is carried out via a venous catheter on a peripheral vein. If long-term use, parenteral nutrition, the administration of vein-irritating drugs (sodium bicarbonate, potassium solution) is intended, a central venous catheter (CVC) with the tip in a central vein is indicated. The port catheter, which is used for chemotherapy, is a special form of the CVC.

The intraosseous puncture and infusion therapy via the bone marrow is reserved for emergencies and is used in particular in children. In human medicine, subcutaneous infusions are being carried out more and more frequently, especially in geriatrics and palliative medicine, although not all drugs are suitable for this form of administration. In veterinary medicine, subcutaneous infusion is very common.

dosage

The dropping speed is metered using a simple roller clamp of the infusion system (gravity infusion). Precise dosing is only possible using infusion pumps. A special form of infusion are the so-called syringe pumps (perfusors), which administer highly effective medication with low propulsion speeds. Furthermore, large amounts of an infusion can be infused very quickly with a pressure infusion cuff or a pressure infusion device. The connection between the infusion device and the cannula is made with an infusion line, which can be extended with a Heidelberg extension if necessary.

Antiviral

A virostatic (or virustatic, from the Latin virus and Greek.

“Standstill”) is a substance that inhibits the multiplication of viruses. Antivirals are widely used as drugs in the treatment of infectious diseases caused by viruses.

Viruses do not have their own metabolism, which makes a causal treatment of viral infectious diseases difficult. Treatment is often not necessary because viral infections often heal spontaneously. Antivirals are mainly used for infections in which the patient's immune system alone is not able to eradicate the virus. A widespread use is currently not planned, taking into account the potential for side effects and the endeavor to avoid the formation of resistance. The medicinally used substances against viruses have an exclusively virostatic effect. This means that they only prevent the virus from multiplying through various mechanisms of action. There are currently no virucidal drugs - that is, «virus-killing» drugs, apart from isotonic electrolysis water.

Classification of antivirals

Virostatics have different points of attack in the multiplication stages of a virus:

Prevention of the docking of the virus particles on the cell membrane of the host organism.

Prevention of penetration into the host cell, prevention of uncoating (release of capsids and genome from the virus envelope).

Disruption / inhibition of the synthesis of viral nucleic acids and proteins (e.g. capsid proteins).

Inhibition of assembly (assembly of the synthesized virus components to form new viruses).

Suppression of the release of the newly formed viruses from the host cell,

Oxidation by oxidative radicals of the electrolysis water injected by drop infusion.

Bacteriostat

A substance which inhibits the growth of bacteria is referred to as a bacteriostatic agent. If bacteria are killed by a substance, however, one speaks of a bactericide. The distinction between the two terms is not very clear, because high concentrations of bacteriostatics often have a bactericidal effect and very low bactericidal concentrations can have bacteriostatic effects.

Some of the best known bacteriostatics include some antibiotics. They often act as translation inhibitors, for example by binding to the ribosomes and thus inhibiting the protein synthesis of the bacteria. This group includes the tetracyclines (e.g. doxycycline), the macrolides erytromycin, roxythrimycin, clarithomycin and acithromycin and the lincosamides such as clindamycin. Other bacteriostats inhibit DNA synthesis and thus replication, which is why the bacterial cells can no longer divide. A third group of bacteriostats inhibits factors in the metabolic pathways, so that further growth and division of the cells is also prevented. These include the sulfonamides and trimethotrin (which are rarely used today), both of which interfere with the foal acid metabolism.

In combination with the bactericidal effect of the body's immune system, bacteriostatic agents can be used to effectively fight bacterial infections.

Bactericidal

A bactericide is a substance that kills bacteria by damaging the cell.

Bactericides are found in the group of anti-infectives (for example some antibiotics) and disinfectants such as electrolysis water.

The adjective bactericidal describes the killing effect of a substance (e.g. an antibiotic) on bacteria. At least 99% of the pathogens must be killed within the first 4 hours after their application. In comparison, bacteriostatic substances only have a growth-inhibiting effect.

For historical reasons, too, the adjective tuberculocide is used for substances that have a bactericidal effect on tuberculosis pathogens.

Virucidal

Virucides ("virus-killing") are substances which, by damaging the virus nucleic acid or the surface proteins of a virus, reduce or completely prevent the infectivity of viruses. They serve to inactivate viruses outside of living organisms. Substances used therapeutically against viruses are not referred to as virucides, but as antivirals. Certified, virucidal preparations can be found in the DGHM list for disinfectants, which has been tested according to the guidelines of the German Society for Hygiene and Microbiology (guidelines for testing chemical disinfectants).

Electrolysis water was in the laboratory of Dr. MERK in Ochsenhausen, a leading European, recognized laboratory, tested and assessed as an excellent virucide with practically no cytotoxicity.

With the electrolysis water product HYDROSEPT, the inventor holds the rights to a biocide entry at the Federal Office of Public Health in Bern, against bacteria, viruses, yeasts, fungi and viruses Switzerland.

The new invention is intended to show that with the help of the new water electrolysis technology using electrolyzed neutral electrolysis water (pH 7.34), produced with boron-doped diamond electrodes or other chemically stable, metallic electrodes, with an electrical Overpotential of 2-4 volts, and with the addition of salts (NaCl, KCl etc.) a new method was developed that can be used for the intravenous injection of isotonic-physiological electrolysis water to combat systemic viruses and bacterioses by means of oxidative radicals, without cytotoxicity and resistances can occur, since pathogens are oxidized cold and pathogens have no defense mechanisms against oxidation.

In addition, during electrolysis by means of electrochemical separation of the water molecule clusters from 14-18 molecules to 2-3 molecules, the hydration potential of water for percutaneous penetration can be increased by 3 to 4 times. As a result, disinfecting, biocidal electrolysis water can penetrate much better and faster through cell membranes and eukaryotic membranes such as ribosomes and mitochondria, since the water molecules are much smaller and cell membranes can pass through osmotic forces more quickly.

Since there are free electrons in the electrolysis water thanks to the electrical overpotential of the boron-doped diamond electrodes, what is known as electrical microstimulation manifests itself in the membrane or wound cells upon contact with membrane tissue, which leads to increased cell metabolism and thus regeneration and doubles the healing process of tissues. Cellular wounds therefore heal twice as quickly when used in practice!

In addition, thanks to the electrochemical splitting of the water molecules and the salts dissolved in the water, salty, neutral electrolysis water produced with diamond electrodes has oxidative radicals such as ozone (03), hydrogen peroxide, hypochlorides, hypochlorides, acids and other peroxides such as peroxydisulfates, Peroxydicarbonates, singlet oxygen, and hydroxide radicals etc. are formed.

In the mix, these radicals have an excellent biocidal effect against bacteria, viruses, fungi, yeasts, bacteriophages and monocygotes and can easily penetrate tissue and cell membranes. At the same time, the oxygen ions produced electrochemically during the electrolysis also contribute to the stimulation of the intracellular metabolic processes, which contribute significantly to cell regeneration after viruses or bacterial attack. The hydrogen ions also formed during the electrolysis neutralize and also eliminate toxic cytotoxins that can arise in viroses and bacterioses.

The use of electrolysis water of this type does not leave any toxic residues, but only salts that are absorbed by the blood and can be excreted again by the kidneys.

Conventionally produced electrolysis water in generators with membrane technology (diaphragm) is not stable and efficient for the specified intravenous applications and also contains only chlorine compounds. (Hypochlorite OCI and hypochlorite acid HCIO).

In addition, the new medical technology is extremely user-friendly, since the virucidal and bactericidal electrolysis water solution can be carried out with the aid of an intravenous needle infusion. There is also no longer any need to use drugs with side effects. The treatment can be repeated numerous times a day as required. In addition, the physiological (with 0.9% salt content) electrolysis water is not cytotoxic up to 1000 ppm free chlorine content.

The use of electrolysis water in these forms is also very cost-effective compared to other medical or cosmetic products or antibiotics and also does not generate any resistance to germs, since the disinfecting effect is based on cold oxidation, against which organisms such as germs biologically can not protect!

The invention is efficient, inventive, and innovative for the reasons mentioned above. The inventor is not aware of any similar technologies for the systemic elimination of viruses and bacteria as biocides by infusion in the blood plasma, produced by means of diamond electrodes.

The new treatment technology has currently been successfully tested in the laboratory and in practical application tests with animals and assessed as very efficient, ecological and sustainable. The corresponding human experiments are planned.

Plant components

Technical aids

An electrical ELECTROLYSIS MACHINE with storage tank contains the following essential parts: 1. Electrolysis generator with preferably one or more single-chamber electrolysis cells, connected in parallel, preferably with boron doped diamond electrodes or metallic mixed electrodes with electrical overpotential, pump made of corrosion-free material with a Pumping capacity of preferably 100 to 1000 liters per hour and 4 bar pressure, filter with preferably 50 mesh, flow meter up to 1000 liters per hour, pressure regulation with preferably 2 taps and 2 manometers, electrical water flow sensor, electronic control unit with time-controlled automatic electrode reverse polarization , Redox meter, mSiemens / cm conductivity meter and water thermometer sensor. 2. Water tank made of corrosion-resistant plastic, preferably with a capacity of 1000 liters, with electrical level control and tank ventilation device. 3. Brine container with injection pump or venturi, which is connected to the electrolysis machine via a hose connection. 4. Filling station for infusion bags. 5. Infusion bag or infusion device with hand control or battery operated pump with applicator and needle including flow regulation Microfiber fiber cloth for disinfecting the infusion site.

Implementation of the invention

The invention is to be demonstrated using the example of a medical application.

The isotonic electrolysis water is produced as an iso-osmotic solution from table salt (sodium chloride) and water. It contains 9 g of table salt (sodium chloride) per liter (0.9% m / V) and has an osmolarity of 308 mosmol / l. The isotonic saline solution is inexpensive and the most widely used infusion solution in the world. Electrolytically oxidative water (EOW) or chemically active water destroys microorganisms such as viruses, bacteria, fungi, yeasts and protozoa through oxidative radicals not chemically, but physically. Because of its high oxidative reduction potential (ORP), «active water» damages the cell wall membranes of pathogens. The pathogen is compromised, which leads to an osmotic or hydrogen overload inside the cell. Since it is a physical principle of destruction, there is no evidence of resistance to pathogens. At the same time, the water molecule clusters that make up water are electrochemically split from 14 to 18 in certain cases up to 60 molecules per cluster into 3 molecules, which leads to a 3-4-fold improvement in cell membrane resorption.

The following electrolysis devices are suitable for the electrolysis of such an isotonic solution:

1. Electrolysis generator with preferably one or more single-chamber electrolysis cells, connected in parallel, with preferably boron doped diamond electrodes or metallic mixed electrodes with electrical overpotential, pump made of corrosion-free material with a suction capacity of preferably 100 to 1000 liters per Hour and 4 bar pressure, filter with preferably 50 mesh, flow meter up to 1000 liters per hour, pressure regulation with preferably 2 taps and 2 manometers, electrical water flow sensor, electronic control unit with time-controlled automatic electrode reverse polarization, redox meter, m Siemens / cm conductivity meter and water thermometer sensor.

2. Water tank made of corrosion-resistant plastic, preferably with a capacity of 1000 liters with electrical level control and tank ventilation device.

3. Brine container with injection pump or venturi, which is connected to the electrolysis machine via a hose connection.

4. Filling station for infusion bags.

5. Infusion bag or infusion device with manual control or battery operated pump with applicator and needle including flow regulation Microfiber fiber cloth for disinfecting the infusion site.

The mineral water provided with 9 g is pumped through the electrolysis generator with an energy consumption of 48 V and 12.8 A. The electrolysis water obtained then contains the following oxidative radicals and a pH of 7.34, an osmolarity of 308 mosmol / l and an osmotic pressure of 7.6 bar. The electrolysis water then also contains the following oxidative radicals: 1000 ppm free chlorine hypochlorite and hypochlorite acid 1 ppm ozone 0.7 ppm H2O2 (hydrogen peroxide), peroxydisulfates, peroxydicarbonates, singlet oxygen, and hydroxide radicals. This solution is then packaged aseptically in a light-protected PET bag. The electrolysis water infusion solution is ready for infusion! The electrolysis water solution can be kept for one year without damage when cooled to 4C ° and protected from light.

administration

Application forms

The intravenous standard application of electrolysis water as an infusion solution is carried out via a venous catheter on a peripheral vein. If long-term use of oxidative isotonic electrolysis water, which irritates the veins, is necessary, a central venous catheter (CVC) is indicated as a port catheter, the tip of which is located in a central vein.

Claims (8)

1. A method for the intravenous injection of isotonic-physiological electrolysis water for the control of systemic viruses and bacterioses by means of oxidative radicals. 2. The method according to claim 1, characterized in that the isotonic-physiological electrolysis water has a pH of 7.34 and a maximum salt concentration (NaCl, KCl) of 0.9%, an osmolarity of 308 mosmol / l and an osmotic pressure of 7.6 bar. 3. The method according to claims 1 and 2, characterized in that the described electrolysis in an electrolysis generator with one or more single-chamber electrolysis cells, connected in parallel with boron doped diamond electrodes or metallic mixing electrodes with electrical overpotential pump with corrosion-free material a pouring capacity of 100 to 1000 liters per hour and 4 bar pressure, filter preferably 50 mesh, flow meter to 1000 liters per hour, pressure control with preferably 2 taps and 2 pressure gauges, electric water flow sensor, electronic control unit with time-controlled automatic electrode reverse polarization , Redox meter, mSiemens / cm conductance meter and water thermometer sensor is equipped. 4. The method according to claims 1, 2, and 3, characterized in that the electrolysis plant has a water tank made of corrosion-resistant plastic, with electrical level control and tank venting, a brine tank with injection pump or Venturi, which is connected to the electrolysis machine via a hose connection is and has an aseptic filling station for infusion solutions in the bag. 5. The method according to claim 1 to 4, characterized in that the hydrogenating, disinfecting and microelectrically stimulating electrolysis water is injected as an infusion solution by means of a venous catheter to a peripheral vein. If a long-term use of oxidative isotonic electrolysis water is required, which irritates the veins, a central venous catheter (CVC) is indicated as a port catheter, the tip of which comes to lie in a central vein. 6. The method according to claims 1 to 5, characterized in that the produced electrolysis water contains micro-clusters of 2-4 water molecules, which has an improved cell membrane permeability and has disinfecting oxidative radicals, such as hypochlorite, hypochlorite acid, ozone, Hydrogen peroxide, mineral peroxides, oxygen and hydrogen, and also has an excess of electrons in the aqueous solution that can induce electrical microstimulation of the eukaryotes in tissue cells to stimulate metabolic processes in cell tissues to accelerate cell regeneration. 7. The method according to claims 1 to 6, characterized in that the produced electrolysis water has disinfecting, biocidal, oxidative radicals, such as hypochlorite, hypochlorite acid, ozone, hydrogen peroxide and mineral peroxides by oxidation viruses, bacteria, fungi and yeasts in the blood and destroy them in cells without causing cytotoxicity and without causing toxic residues and harmful side effects. 8. A method for the intravenous injection of isotonic-physiological electrolysis water for controlling systemic viruses and bacterioses by means of oxidative radicals, characterized in that the oxidative radicals such as hypochlorite, hypochlorite acid, ozone, hydrogen peroxide, mineral peroxides, oxygen and hydrogen, even in multidrug-resistant viruses and Bacterial germs against antivirals and bactericides show a good effect and also produce no resistance to viruses, bacteria, fungi and yeasts in cells and in the blood because of their high oxidation potential.