CH653325A5 - Process for synthesis of 1-(4-isopropylthiophenyl)-2-(n-octylamino)propanol, of its esters and of its salts - Google Patents

Process for synthesis of 1-(4-isopropylthiophenyl)-2-(n-octylamino)propanol, of its esters and of its salts Download PDF

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Publication number
CH653325A5
CH653325A5 CH8259/81A CH825981A CH653325A5 CH 653325 A5 CH653325 A5 CH 653325A5 CH 8259/81 A CH8259/81 A CH 8259/81A CH 825981 A CH825981 A CH 825981A CH 653325 A5 CH653325 A5 CH 653325A5
Authority
CH
Switzerland
Prior art keywords
octylaminopropanol
formula
salts
synthesis
isopropylthiophenyl
Prior art date
Application number
CH8259/81A
Other languages
English (en)
French (fr)
Inventor
Georges E Lambelin
Claude Gillet
Johnny Hermans
Original Assignee
Continental Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Continental Pharma filed Critical Continental Pharma
Publication of CH653325A5 publication Critical patent/CH653325A5/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C313/00—Sulfinic acids; Sulfenic acids; Halides, esters or anhydrides thereof; Amides of sulfinic or sulfenic acids, i.e. compounds having singly-bound oxygen atoms of sulfinic or sulfenic groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/32—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
CH8259/81A 1980-12-24 1981-12-23 Process for synthesis of 1-(4-isopropylthiophenyl)-2-(n-octylamino)propanol, of its esters and of its salts CH653325A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU83039A LU83039A1 (fr) 1980-12-24 1980-12-24 Procedes de synthese du 1-(4 isopropylthiophenyl)-2-n octylaminopropanol

Publications (1)

Publication Number Publication Date
CH653325A5 true CH653325A5 (en) 1985-12-31

Family

ID=19729552

Family Applications (2)

Application Number Title Priority Date Filing Date
CH8259/81A CH653325A5 (en) 1980-12-24 1981-12-23 Process for synthesis of 1-(4-isopropylthiophenyl)-2-(n-octylamino)propanol, of its esters and of its salts
CH443/85A CH654296A5 (en) 1980-12-24 1981-12-23 Process for the synthesis of 1-(4-isopropylthiophenyl)-2-(n-octylamino)propanol, of its esters and of its salts

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH443/85A CH654296A5 (en) 1980-12-24 1981-12-23 Process for the synthesis of 1-(4-isopropylthiophenyl)-2-(n-octylamino)propanol, of its esters and of its salts

Country Status (11)

Country Link
JP (4) JPS5912665B2 (de)
KR (1) KR860000340B1 (de)
AR (1) AR229799A1 (de)
AT (1) AT380872B (de)
AU (1) AU548084B2 (de)
CH (2) CH653325A5 (de)
ES (4) ES8308844A1 (de)
IL (1) IL64631A0 (de)
IT (1) IT1140399B (de)
LU (1) LU83039A1 (de)
PT (1) PT74203B (de)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1321701A (en) * 1969-10-01 1973-06-27 Continental Pharma Amino-alcohols their salts and process for prepairing the same
GB1390748A (en) * 1973-04-09 1975-04-16 Continental Pharma Alkyl and cycloalkylthiophenylalkylaminoalkanols their salts and the preparation thereof
LU77237A1 (de) * 1977-05-03 1979-01-18
IT1082122B (it) * 1977-07-11 1985-05-21 Medea Res Srl Processo per la preparazione dell'1-(4-isopropilmercapto-fenil)-2-n.ottilammino-propanolo
LU79970A1 (fr) * 1978-07-13 1980-02-14 Continental Pharma Procede de preparation de derives de 1-phenyl-1-propanol

Also Published As

Publication number Publication date
KR830007541A (ko) 1983-10-21
IT1140399B (it) 1986-09-24
PT74203A (fr) 1982-01-01
ES8407020A1 (es) 1984-08-16
ES8407019A1 (es) 1984-08-16
JPS5915906B2 (ja) 1984-04-12
JPS5912665B2 (ja) 1984-03-24
JPS57134459A (en) 1982-08-19
JPS5915905B2 (ja) 1984-04-12
ES508313A0 (es) 1983-10-01
ES522442A0 (es) 1984-08-16
KR860000340B1 (ko) 1986-04-12
AU548084B2 (en) 1985-11-21
ATA549881A (de) 1985-12-15
AU7902581A (en) 1982-07-01
CH654296A5 (en) 1986-02-14
ES522440A0 (es) 1984-08-16
PT74203B (fr) 1983-05-20
JPS58113170A (ja) 1983-07-05
AR229799A1 (es) 1983-11-30
JPS58113169A (ja) 1983-07-05
ES8308844A1 (es) 1983-10-01
AT380872B (de) 1986-07-25
LU83039A1 (fr) 1982-07-07
ES522441A0 (es) 1984-08-16
IL64631A0 (en) 1982-03-31
ES8407018A1 (es) 1984-08-16
IT8125853A0 (it) 1981-12-24
JPS58113171A (ja) 1983-07-05
JPS5938224B2 (ja) 1984-09-14

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PL Patent ceased