CH647871A5 - Reactif de lysat d'amibocytes de limule. - Google Patents
Reactif de lysat d'amibocytes de limule. Download PDFInfo
- Publication number
- CH647871A5 CH647871A5 CH4249/81A CH424981A CH647871A5 CH 647871 A5 CH647871 A5 CH 647871A5 CH 4249/81 A CH4249/81 A CH 4249/81A CH 424981 A CH424981 A CH 424981A CH 647871 A5 CH647871 A5 CH 647871A5
- Authority
- CH
- Switzerland
- Prior art keywords
- radical
- lysate
- sensitivity
- carbon atoms
- reagent according
- Prior art date
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- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- IYFATESGLOUGBX-YVNJGZBMSA-N Sorbitan monopalmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O IYFATESGLOUGBX-YVNJGZBMSA-N 0.000 description 1
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 1
- IFZPTPZMISZREH-UHFFFAOYSA-N [2,4-bis(hydroxymethyl)-1h-imidazol-5-yl]methanol Chemical compound OCC1=NC(CO)=C(CO)N1 IFZPTPZMISZREH-UHFFFAOYSA-N 0.000 description 1
- UUXKYWQZAAZOSD-UHFFFAOYSA-N [Na].C1=CC=C2C(S(=O)(=O)OCCCCCCCCCCCCCCCCCCCCCC)=CC=CC2=C1 Chemical compound [Na].C1=CC=C2C(S(=O)(=O)OCCCCCCCCCCCCCCCCCCCCCC)=CC=CC2=C1 UUXKYWQZAAZOSD-UHFFFAOYSA-N 0.000 description 1
- 238000010306 acid treatment Methods 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 229910001413 alkali metal ion Inorganic materials 0.000 description 1
- 239000012670 alkaline solution Substances 0.000 description 1
- 150000003973 alkyl amines Chemical class 0.000 description 1
- 150000008051 alkyl sulfates Chemical group 0.000 description 1
- 150000001450 anions Chemical class 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- 239000008346 aqueous phase Substances 0.000 description 1
- 230000003416 augmentation Effects 0.000 description 1
- PLUHAVSIMCXBEX-UHFFFAOYSA-N azane;dodecyl benzenesulfonate Chemical compound N.CCCCCCCCCCCCOS(=O)(=O)C1=CC=CC=C1 PLUHAVSIMCXBEX-UHFFFAOYSA-N 0.000 description 1
- QPLUNEMZWJHTGH-UHFFFAOYSA-N azanium;2-dodecyl-3-methylbenzenesulfonate Chemical compound [NH4+].CCCCCCCCCCCCC1=C(C)C=CC=C1S([O-])(=O)=O QPLUNEMZWJHTGH-UHFFFAOYSA-N 0.000 description 1
- VPDKMELSVLIAOG-UHFFFAOYSA-N azanium;decyl sulfate Chemical compound N.CCCCCCCCCCOS(O)(=O)=O VPDKMELSVLIAOG-UHFFFAOYSA-N 0.000 description 1
- ACWQSLXTIYNAJO-UHFFFAOYSA-N azanium;nonyl sulfate Chemical compound [NH4+].CCCCCCCCCOS([O-])(=O)=O ACWQSLXTIYNAJO-UHFFFAOYSA-N 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- FQEONVSBIOOXJN-UHFFFAOYSA-N bis(2-hydroxyethyl)azanium;octyl sulfate Chemical compound OCCNCCO.CCCCCCCCOS(O)(=O)=O FQEONVSBIOOXJN-UHFFFAOYSA-N 0.000 description 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 229910001424 calcium ion Inorganic materials 0.000 description 1
- BUZRUIZTMOKRPB-UHFFFAOYSA-N carboxycarbamic acid Chemical class OC(=O)NC(O)=O BUZRUIZTMOKRPB-UHFFFAOYSA-N 0.000 description 1
- 238000012754 cardiac puncture Methods 0.000 description 1
- 230000006037 cell lysis Effects 0.000 description 1
- 229960000541 cetyl alcohol Drugs 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 150000001805 chlorine compounds Chemical class 0.000 description 1
- 230000035602 clotting Effects 0.000 description 1
- 108010045487 coagulogen Proteins 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000008260 defense mechanism Effects 0.000 description 1
- GVGUFUZHNYFZLC-UHFFFAOYSA-N dodecyl benzenesulfonate;sodium Chemical compound [Na].CCCCCCCCCCCCOS(=O)(=O)C1=CC=CC=C1 GVGUFUZHNYFZLC-UHFFFAOYSA-N 0.000 description 1
- SYELZBGXAIXKHU-UHFFFAOYSA-N dodecyldimethylamine N-oxide Chemical compound CCCCCCCCCCCC[N+](C)(C)[O-] SYELZBGXAIXKHU-UHFFFAOYSA-N 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 238000001962 electrophoresis Methods 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 238000006911 enzymatic reaction Methods 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 238000001879 gelation Methods 0.000 description 1
- 150000002327 glycerophospholipids Chemical class 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 150000002431 hydrogen Chemical class 0.000 description 1
- 125000001165 hydrophobic group Chemical group 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 229910001416 lithium ion Inorganic materials 0.000 description 1
- 230000004807 localization Effects 0.000 description 1
- 150000004668 long chain fatty acids Chemical class 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 229910001629 magnesium chloride Inorganic materials 0.000 description 1
- 229910001425 magnesium ion Inorganic materials 0.000 description 1
- 239000011565 manganese chloride Substances 0.000 description 1
- 235000002867 manganese chloride Nutrition 0.000 description 1
- 229910001437 manganese ion Inorganic materials 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 229940043348 myristyl alcohol Drugs 0.000 description 1
- 125000001421 myristyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- IBOBFGGLRNWLIL-UHFFFAOYSA-N n,n-dimethylhexadecan-1-amine oxide Chemical compound CCCCCCCCCCCCCCCC[N+](C)(C)[O-] IBOBFGGLRNWLIL-UHFFFAOYSA-N 0.000 description 1
- RSVIRMFSJVHWJV-UHFFFAOYSA-N n,n-dimethyloctan-1-amine oxide Chemical compound CCCCCCCC[N+](C)(C)[O-] RSVIRMFSJVHWJV-UHFFFAOYSA-N 0.000 description 1
- VHXSGTCOHZCUKB-UHFFFAOYSA-N n,n-dimethyltridecan-1-amine oxide Chemical compound CCCCCCCCCCCCC[N+](C)(C)[O-] VHXSGTCOHZCUKB-UHFFFAOYSA-N 0.000 description 1
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 description 1
- 125000000740 n-pentyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- KIHUPOKUSVEICJ-UHFFFAOYSA-N nonyl benzenesulfonate;sodium Chemical compound [Na].CCCCCCCCCOS(=O)(=O)C1=CC=CC=C1 KIHUPOKUSVEICJ-UHFFFAOYSA-N 0.000 description 1
- SNQQPOLDUKLAAF-UHFFFAOYSA-N nonylphenol Chemical compound CCCCCCCCCC1=CC=CC=C1O SNQQPOLDUKLAAF-UHFFFAOYSA-N 0.000 description 1
- MXXDSLLVYZMTFA-UHFFFAOYSA-N octadecyl benzenesulfonate;sodium Chemical compound [Na].CCCCCCCCCCCCCCCCCCOS(=O)(=O)C1=CC=CC=C1 MXXDSLLVYZMTFA-UHFFFAOYSA-N 0.000 description 1
- DZQYCOCAFPQWBL-UHFFFAOYSA-N octadecyl sulfate;tris(2-hydroxyethyl)azanium Chemical compound OCCN(CCO)CCO.CCCCCCCCCCCCCCCCCCOS(O)(=O)=O DZQYCOCAFPQWBL-UHFFFAOYSA-N 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 239000006259 organic additive Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- FSYKKLYZXJSNPZ-UHFFFAOYSA-N sarcosine Chemical compound C[NH2+]CC([O-])=O FSYKKLYZXJSNPZ-UHFFFAOYSA-N 0.000 description 1
- 238000013207 serial dilution Methods 0.000 description 1
- 229940080264 sodium dodecylbenzenesulfonate Drugs 0.000 description 1
- 229910001415 sodium ion Inorganic materials 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- URLJMZWTXZTZRR-UHFFFAOYSA-N sodium myristyl sulfate Chemical compound CCCCCCCCCCCCCCOS(O)(=O)=O URLJMZWTXZTZRR-UHFFFAOYSA-N 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- RLJSXMVTLMHXJS-UHFFFAOYSA-M sodium;4-decylbenzenesulfonate Chemical compound [Na+].CCCCCCCCCCC1=CC=C(S([O-])(=O)=O)C=C1 RLJSXMVTLMHXJS-UHFFFAOYSA-M 0.000 description 1
- GGHPAKFFUZUEKL-UHFFFAOYSA-M sodium;hexadecyl sulfate Chemical compound [Na+].CCCCCCCCCCCCCCCCOS([O-])(=O)=O GGHPAKFFUZUEKL-UHFFFAOYSA-M 0.000 description 1
- FTWCSAMTIKSPAT-UHFFFAOYSA-M sodium;nonyl sulfate Chemical compound [Na+].CCCCCCCCCOS([O-])(=O)=O FTWCSAMTIKSPAT-UHFFFAOYSA-M 0.000 description 1
- NWZBFJYXRGSRGD-UHFFFAOYSA-M sodium;octadecyl sulfate Chemical compound [Na+].CCCCCCCCCCCCCCCCCCOS([O-])(=O)=O NWZBFJYXRGSRGD-UHFFFAOYSA-M 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
- 229940035044 sorbitan monolaurate Drugs 0.000 description 1
- 239000001593 sorbitan monooleate Substances 0.000 description 1
- 235000011069 sorbitan monooleate Nutrition 0.000 description 1
- 229940035049 sorbitan monooleate Drugs 0.000 description 1
- 235000011071 sorbitan monopalmitate Nutrition 0.000 description 1
- 239000001570 sorbitan monopalmitate Substances 0.000 description 1
- 229940031953 sorbitan monopalmitate Drugs 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 229910052712 strontium Inorganic materials 0.000 description 1
- CIOAGBVUUVVLOB-UHFFFAOYSA-N strontium atom Chemical compound [Sr] CIOAGBVUUVVLOB-UHFFFAOYSA-N 0.000 description 1
- 229910001631 strontium chloride Inorganic materials 0.000 description 1
- AHBGXTDRMVNFER-UHFFFAOYSA-L strontium dichloride Chemical compound [Cl-].[Cl-].[Sr+2] AHBGXTDRMVNFER-UHFFFAOYSA-L 0.000 description 1
- 229910001427 strontium ion Inorganic materials 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 150000003512 tertiary amines Chemical class 0.000 description 1
- POSZUTFLHGNLHX-KSBRXOFISA-N tris maleate Chemical compound OCC(N)(CO)CO.OCC(N)(CO)CO.OC(=O)\C=C/C(O)=O POSZUTFLHGNLHX-KSBRXOFISA-N 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Cosmetics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16345680A | 1980-06-27 | 1980-06-27 | |
| US06/254,233 US4322217A (en) | 1980-06-27 | 1981-04-14 | Process for preparing Limulus lysate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH647871A5 true CH647871A5 (fr) | 1985-02-15 |
Family
ID=26859656
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH4249/81A CH647871A5 (fr) | 1980-06-27 | 1981-06-26 | Reactif de lysat d'amibocytes de limule. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4322217A (en, 2012) |
| AU (1) | AU545395B2 (en, 2012) |
| CH (1) | CH647871A5 (en, 2012) |
| DE (1) | DE3125181A1 (en, 2012) |
| FR (1) | FR2485740A1 (en, 2012) |
| GB (1) | GB2080524B (en, 2012) |
| IT (1) | IT1211070B (en, 2012) |
| NL (1) | NL8103113A (en, 2012) |
| SE (1) | SE447029B (en, 2012) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8827557D0 (en) * | 1988-11-25 | 1988-12-29 | Radiometer Corporate Dev Ltd | Process for handling horseshoe crab amoebocyte lysate |
| US5002015A (en) * | 1988-12-09 | 1991-03-26 | Aerotrace Hydraulics, Inc. | Submerged treadmill system for exercising animals |
| DE69029785T2 (de) * | 1989-10-30 | 1997-05-28 | Biowhittaker Inc | Kinetische Bestimmungsmethode für Endotoxin unter Verwendung von Limulus-Amoebocyten-Lysat und chromogenem Substrat |
| JP2957251B2 (ja) * | 1990-09-28 | 1999-10-04 | 生化学工業株式会社 | エンドトキシンの測定法 |
| DE69211973T2 (de) * | 1991-12-25 | 1996-12-19 | Maruha Corp | Reagenzien und Verfahren zur Bestimmung von Beta-Glucanen |
| JP2737514B2 (ja) * | 1992-01-24 | 1998-04-08 | 和光純薬工業株式会社 | エンドトキシン測定用試料の前処理方法 |
| CA2112776C (en) * | 1993-01-21 | 2002-11-12 | Masakazu Tsuchiya | Process for inhibiting activity of endotoxin |
| JP3242733B2 (ja) * | 1993-02-26 | 2001-12-25 | 生化学工業株式会社 | エンドトキシン特異的測定剤 |
| JP3429036B2 (ja) * | 1993-09-30 | 2003-07-22 | 生化学工業株式会社 | エンドトキシンの特異的測定剤 |
| US5716834A (en) * | 1994-08-19 | 1998-02-10 | National University Of Singapore | Cloned factor C cDNA of the Singapore horseshoe crab, Carcinoscorpius rotundicauda and purification of factor C proenzyme |
| US5637474A (en) * | 1994-10-31 | 1997-06-10 | Wako Pure Chemical Industries, Ltd. | Process for measuring amount of endotoxin or (1→3)-β-D-glucan by kinetic turbidimetric method |
| US6270982B1 (en) | 1997-10-09 | 2001-08-07 | Charles River Laboratories | Methods and compositions for the detection of bacterial endotoxins |
| ATE437886T1 (de) * | 2001-06-28 | 2009-08-15 | Lonza Walkersville Inc | Verfahren und reagentien zum nachweis von endotoxin |
| US20040138577A1 (en) * | 2002-12-20 | 2004-07-15 | Kline Jeffrey A. | Disposable hand-held device for collection of exhaled breath condensate |
| US7828741B2 (en) * | 2002-12-20 | 2010-11-09 | The Charlotte-Mecklenburg Hospital Authority | Utilizing lipopolysaccharide in exhaled breath condensate to diagnose gram negative pneumonia |
| WO2004073497A2 (en) * | 2003-02-14 | 2004-09-02 | The Charlotte-Mecklenburg Hospital Authority | Device and method for collection of exhaled alveolar breath condensate |
| EP1606414B1 (en) | 2003-03-17 | 2009-12-23 | Charles River Laboratories, Inc. | Methods and compositions for the detection of microbial contaminants |
| EP1627040A2 (en) * | 2003-04-18 | 2006-02-22 | Associates Of Cape Cod, Inc. | Kit for detecting endotoxin in aqueous solutions |
| US20050048655A1 (en) * | 2003-04-18 | 2005-03-03 | Novitsky Thomas J. | Kit for detecting endotoxin |
| US7968280B2 (en) * | 2004-12-02 | 2011-06-28 | Charles River Laboratories, Inc. | Methods for the detection and/or quantification of gram positive bacterial contaminants |
| JP5096166B2 (ja) | 2005-01-13 | 2012-12-12 | チャールズ リバー ラボラトリーズ， インコーポレイテッド | 生体サンプル中の微生物を分類する方法 |
| US20090286692A1 (en) * | 2008-04-15 | 2009-11-19 | Wainwright Norman R | Cartridge and Method for Sample Analysis |
| EP2147981A1 (en) | 2008-07-25 | 2010-01-27 | Biotype AG | Kit and method for evaluating detection properties in amplification reactions |
| JP5437660B2 (ja) | 2009-02-19 | 2014-03-12 | 興和株式会社 | コアギュロゲン原料及びその製造方法、それを用いた生物由来の生理活性物質の測定方法及び測定装置 |
| MY155541A (en) * | 2010-10-29 | 2015-10-30 | Universiti Malaysia Terengganu | Process for the preparation of amoebocyte lysate from the haemolymph of the horseshoe crab |
| CU24073B1 (es) | 2011-12-27 | 2015-01-29 | Ct De Investigación Y Desarrollo De Medicamentos Cidem | COMPOSICIÓN A PARTIR DE EXTRACTO DE HEMOCITOS DE LANGOSTA PARA LA DETECCIÓN DE LIPOPOLISACÁRIDOS, PEPTIDOGLICANOS Y 1,3-ß-D-GLUCANOS |
| EP3494226B1 (en) | 2016-08-03 | 2021-09-22 | Lonza Walkersville, Inc. | Method of detecting an endotoxin using limulus amebocyte lysate substantially free of coagulogen |
| US12158471B2 (en) | 2022-02-11 | 2024-12-03 | Charles River Laboratories, Inc. | Recombinant amebocyte lysate and uses thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3280179A (en) * | 1961-03-16 | 1966-10-18 | Textilana Corp | Processes for producing acyclic surfactant sulfobetaines |
| US3368978A (en) * | 1964-12-28 | 1968-02-13 | Monsanto Co | Builder compositions and detergent compositions using same |
| US3539521A (en) * | 1965-05-03 | 1970-11-10 | Procter & Gamble | Detergent composition |
| US3915805A (en) * | 1970-05-25 | 1975-10-28 | Univ Johns Hopkins | Quantitative detection of endotoxin in biological fluids |
| US3954663A (en) * | 1972-12-18 | 1976-05-04 | Teikoku Horinine Mfg. Co. Ltd. | Process for the preparation of Limulina lysate |
| US4096091A (en) * | 1974-07-17 | 1978-06-20 | Baxter Travenol Laboratories, Inc. | Limulus lysate having improved capacity to precipitate in the presence of low endotoxin concentrations, and reconstituting solutions therefor |
| US3944391A (en) | 1974-12-27 | 1976-03-16 | Preventive Systems, Inc. | In vitro process for detecting endotoxin in a biological fluid |
| US4107077A (en) * | 1975-07-14 | 1978-08-15 | Associates Of Cape Cod, Inc. | Limulus lysate of improved sensitivity and preparing the same |
| US4038029A (en) * | 1976-01-20 | 1977-07-26 | Worthington Biochemical Corporation | Limulus lysate turbidity test for pyrogens |
| GB1522127A (en) | 1976-07-23 | 1978-08-23 | Mallinckrodt Inc | Limulus amebocyte lysate reagent compositions |
| GB2019563B (en) | 1978-04-20 | 1982-07-28 | Harvard College | Assay of gram-negative bacteria |
| DE2927103A1 (de) * | 1978-10-06 | 1980-04-17 | Baxter Travenol Lab | Optisches verfahren zur bestimmung von endotoxin |
| US4273557A (en) * | 1980-03-31 | 1981-06-16 | Mallinckrodt, Inc. | Limulus lysate procedure for determining endotoxins |
-
1981
- 1981-04-14 US US06/254,233 patent/US4322217A/en not_active Expired - Lifetime
- 1981-06-23 GB GB8119357A patent/GB2080524B/en not_active Expired
- 1981-06-26 NL NL8103113A patent/NL8103113A/nl not_active IP Right Cessation
- 1981-06-26 SE SE8104016A patent/SE447029B/sv not_active IP Right Cessation
- 1981-06-26 CH CH4249/81A patent/CH647871A5/fr not_active IP Right Cessation
- 1981-06-26 IT IT8122595A patent/IT1211070B/it active
- 1981-06-26 AU AU72321/81A patent/AU545395B2/en not_active Expired
- 1981-06-26 DE DE19813125181 patent/DE3125181A1/de active Granted
- 1981-06-26 FR FR8112598A patent/FR2485740A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DE3125181C2 (en, 2012) | 1991-09-05 |
| NL8103113A (nl) | 1982-01-18 |
| SE447029B (sv) | 1986-10-20 |
| SE8104016L (sv) | 1981-12-28 |
| GB2080524B (en) | 1984-04-18 |
| AU545395B2 (en) | 1985-07-11 |
| DE3125181A1 (de) | 1982-03-04 |
| IT1211070B (it) | 1989-09-29 |
| NL192139B (en, 2012) | 1996-10-01 |
| US4322217A (en) | 1982-03-30 |
| FR2485740A1 (fr) | 1981-12-31 |
| FR2485740B1 (en, 2012) | 1985-05-24 |
| IT8122595A0 (it) | 1981-06-26 |
| GB2080524A (en) | 1982-02-03 |
| AU7232181A (en) | 1982-01-07 |
| NL192139C (en, 2012) | 1997-02-04 |
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