CH640236A5 - 3-(2-Aminoethylthio)-6-ethyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2 -carboxylic acid and process for its preparation - Google Patents

3-(2-Aminoethylthio)-6-ethyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2 -carboxylic acid and process for its preparation Download PDF

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Publication number
CH640236A5
CH640236A5 CH379278A CH379278A CH640236A5 CH 640236 A5 CH640236 A5 CH 640236A5 CH 379278 A CH379278 A CH 379278A CH 379278 A CH379278 A CH 379278A CH 640236 A5 CH640236 A5 CH 640236A5
Authority
CH
Switzerland
Prior art keywords
hept
oxo
solution
ethyl
ene
Prior art date
Application number
CH379278A
Other languages
German (de)
English (en)
Inventor
Ronald William Ratcliffe
Linda Jean Ruswinkle
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CH640236A5 publication Critical patent/CH640236A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CH379278A 1977-04-08 1978-04-07 3-(2-Aminoethylthio)-6-ethyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2 -carboxylic acid and process for its preparation CH640236A5 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78581177A 1977-04-08 1977-04-08
US86123077A 1977-12-16 1977-12-16

Publications (1)

Publication Number Publication Date
CH640236A5 true CH640236A5 (en) 1983-12-30

Family

ID=27120448

Family Applications (1)

Application Number Title Priority Date Filing Date
CH379278A CH640236A5 (en) 1977-04-08 1978-04-07 3-(2-Aminoethylthio)-6-ethyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2 -carboxylic acid and process for its preparation

Country Status (11)

Country Link
JP (1) JPS53127491A (sv)
CH (1) CH640236A5 (sv)
DE (1) DE2815157A1 (sv)
DK (1) DK123578A (sv)
FR (1) FR2386545A1 (sv)
GB (1) GB1595267A (sv)
IE (1) IE47043B1 (sv)
IT (1) IT1102456B (sv)
LU (1) LU79403A1 (sv)
NL (1) NL7802826A (sv)
SE (1) SE7803173L (sv)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR62185B (en) * 1977-03-31 1979-03-02 Panlabs Inc Preparation process of an antibiotic ps-5 and its derivatives with inhibitory activity of b-lactamase
JPS5473788A (en) * 1977-11-17 1979-06-13 Sanraku Inc Antibiotic n-desacetyl ps-5
EP0005349A1 (en) * 1978-05-06 1979-11-14 Beecham Group Plc Alkylcarbapenems, their preparation, use in pharmaceutical compositions and intermediates
JPS5572191A (en) * 1978-11-22 1980-05-30 Sanraku Inc Antibiotic n-desacetyl ps-5
JPS55136282A (en) * 1979-04-06 1980-10-23 Shionogi & Co Ltd Novel antibiotic pa-31088-4
US4235922A (en) * 1979-06-15 1980-11-25 Merck & Co., Inc. 3-(2-Aminoethylthio)-6-ethyl-7-oxo-1-azabicyclo [3.2.0]hept-2-ene-2-carboxylic acid
EP0024832B1 (en) * 1979-08-10 1985-03-13 Beecham Group Plc Beta-lactam antibiotics, their preparation, pharmaceutical compositions containing them and their preparation
JPS5683489A (en) * 1979-12-12 1981-07-08 Shionogi & Co Ltd New antibiotic pa-39504-x1 and it preparation
JPS5764693A (en) * 1980-10-07 1982-04-19 Kowa Co Novel carbapenem compound and its preparation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics

Also Published As

Publication number Publication date
IT1102456B (it) 1985-10-07
FR2386545A1 (fr) 1978-11-03
GB1595267A (en) 1981-08-12
IE780631L (en) 1978-10-08
DK123578A (da) 1978-10-09
JPS53127491A (en) 1978-11-07
IE47043B1 (en) 1983-12-14
DE2815157A1 (de) 1978-10-19
LU79403A1 (fr) 1978-11-27
FR2386545B1 (sv) 1980-08-01
IT7848747A0 (it) 1978-04-05
SE7803173L (sv) 1978-10-09
NL7802826A (nl) 1978-10-10

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