CH638982A5 - Composition anticancereuse pour l'administration par d'autres voies que l'injection. - Google Patents

Composition anticancereuse pour l'administration par d'autres voies que l'injection. Download PDF

Info

Publication number
CH638982A5
CH638982A5 CH561979A CH561979A CH638982A5 CH 638982 A5 CH638982 A5 CH 638982A5 CH 561979 A CH561979 A CH 561979A CH 561979 A CH561979 A CH 561979A CH 638982 A5 CH638982 A5 CH 638982A5
Authority
CH
Switzerland
Prior art keywords
ara
ester
cmp
composition according
arabinofuranosylcytosine
Prior art date
Application number
CH561979A
Other languages
English (en)
French (fr)
Inventor
Kenjiro Kodama
Akira Kuninaka
Mineo Saneyoshi
Original Assignee
Yamasa Shoyu Kk
Mineo Saneyoshi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamasa Shoyu Kk, Mineo Saneyoshi filed Critical Yamasa Shoyu Kk
Publication of CH638982A5 publication Critical patent/CH638982A5/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CH561979A 1978-06-20 1979-06-15 Composition anticancereuse pour l'administration par d'autres voies que l'injection. CH638982A5 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7369878A JPS552601A (en) 1978-06-20 1978-06-20 Anti-tumor agent for non-injection use

Publications (1)

Publication Number Publication Date
CH638982A5 true CH638982A5 (fr) 1983-10-31

Family

ID=13525685

Family Applications (1)

Application Number Title Priority Date Filing Date
CH561979A CH638982A5 (fr) 1978-06-20 1979-06-15 Composition anticancereuse pour l'administration par d'autres voies que l'injection.

Country Status (9)

Country Link
US (1) US4542021A (en:Method)
JP (1) JPS552601A (en:Method)
CH (1) CH638982A5 (en:Method)
DE (1) DE2924691A1 (en:Method)
FR (1) FR2429019A1 (en:Method)
GB (1) GB2023422B (en:Method)
IT (1) IT1206968B (en:Method)
NL (1) NL190955C (en:Method)
SE (1) SE455162B (en:Method)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS552602A (en) * 1978-06-20 1980-01-10 Yamasa Shoyu Co Ltd 1-beta-d-arabinofranosylcytosine-5'-phosphoric acid oleyl ester
DE3263939D1 (en) * 1981-12-09 1985-07-04 Teijin Ltd 5-fluoro-2'-deoxyuridine derivatives and a process for the preparation thereof
JPS58225097A (ja) * 1982-06-23 1983-12-27 Yamasa Shoyu Co Ltd ヌクレオシド５′−アルキルもしくはアルケニルりん酸
JPS5925327A (ja) * 1982-07-31 1984-02-09 Hidematsu Hirai 抗腫瘍性複合体の製造方法
DE3773716D1 (de) * 1986-03-24 1991-11-21 Nippon Kayaku Kk Verfahren zur herstellung von monosodiumsalz und dessen monohydrat von 1-beta-d-arabinofuranosylcytosin-5'stearylphosphat und diese enthaltende pharmazeutische zusammensetzung.
DE69330392T2 (de) * 1992-04-03 2001-11-08 Nippon Kayaku K.K., Tokio/Tokyo Cytarabine Ocfosfate enthaltende harte Kapsel
DE4402492A1 (de) * 1994-01-28 1995-08-03 Boehringer Mannheim Gmbh Verfahren zur Herstellung von unsymmetrischen Phosphorsäurediestern
AU2002231190B2 (en) * 2000-12-23 2005-11-03 Creighton University Methods for inducing apoptosis and inhibiting proliferation in cancer cells
US20040072902A1 (en) * 2001-12-24 2004-04-15 Adrian Thomas E. Methods for inducing apoptosis and inhibiting proliferation in cancer cells
US7524831B2 (en) * 2005-03-02 2009-04-28 Schering Corporation Treatments for Flaviviridae virus infection
CN102115485A (zh) * 2009-12-30 2011-07-06 济南圣鲁金药物技术开发有限公司 基于阿糖胞苷结构的前药及其合成方法及应用
JP6562908B2 (ja) 2013-10-11 2019-08-21 ヤンセン バイオファーマ インク． 置換ヌクレオシド、置換ヌクレオチドおよびその類似体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1792447C3 (de) * 1968-09-04 1978-05-11 Fa. Heinrich Mack Nachf., 7919 Au Oral anwendbares, cytostatisches Mittel
DE2438322C3 (de) * 1974-08-09 1979-02-08 Chemische Werke Huels Ag, 4370 Marl Verfahren zur Herstellung von Polymerisaten mit breiter Molekulargewichtsverteilung
FR2287910A1 (fr) * 1974-10-15 1976-05-14 Asahi Chemical Ind Derives nucleotidiques et procede de preparation de ceux-ci
JPS5289681A (en) * 1976-01-22 1977-07-27 Yamasa Shoyu Co Ltd Preparation of aracytidine -5# phosphoric acid ester derivatives
JPS552602A (en) * 1978-06-20 1980-01-10 Yamasa Shoyu Co Ltd 1-beta-d-arabinofranosylcytosine-5'-phosphoric acid oleyl ester

Also Published As

Publication number Publication date
FR2429019A1 (fr) 1980-01-18
DE2924691C2 (en:Method) 1991-10-10
GB2023422A (en) 1980-01-03
JPS5748091B2 (en:Method) 1982-10-14
NL190955C (nl) 1994-11-16
DE2924691A1 (de) 1980-01-17
IT1206968B (it) 1989-05-17
SE7905375L (sv) 1979-12-21
US4542021A (en) 1985-09-17
GB2023422B (en) 1983-01-06
NL7904771A (nl) 1979-12-27
JPS552601A (en) 1980-01-10
FR2429019B1 (en:Method) 1982-11-05
SE455162B (sv) 1988-06-27
IT7949442A0 (it) 1979-06-18
NL190955B (nl) 1994-06-16

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