CH637962A5 - N-Alkyl-N-iminomethyl derivatives of thienamycin - Google Patents

N-Alkyl-N-iminomethyl derivatives of thienamycin Download PDF

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Publication number
CH637962A5
CH637962A5 CH484078A CH484078A CH637962A5 CH 637962 A5 CH637962 A5 CH 637962A5 CH 484078 A CH484078 A CH 484078A CH 484078 A CH484078 A CH 484078A CH 637962 A5 CH637962 A5 CH 637962A5
Authority
CH
Switzerland
Prior art keywords
carbon atoms
radical
group
alkyl
methyl
Prior art date
Application number
CH484078A
Other languages
German (de)
English (en)
Inventor
Burton Grant Christensen
William Joseph Leanza
Kenneth James Wildonger
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CH637962A5 publication Critical patent/CH637962A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CH484078A 1977-05-05 1978-05-03 N-Alkyl-N-iminomethyl derivatives of thienamycin CH637962A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79397577A 1977-05-05 1977-05-05

Publications (1)

Publication Number Publication Date
CH637962A5 true CH637962A5 (en) 1983-08-31

Family

ID=25161306

Family Applications (1)

Application Number Title Priority Date Filing Date
CH484078A CH637962A5 (en) 1977-05-05 1978-05-03 N-Alkyl-N-iminomethyl derivatives of thienamycin

Country Status (13)

Country Link
JP (1) JPS53137993A (ko)
BE (1) BE866661A (ko)
CH (1) CH637962A5 (ko)
DE (1) DE2819453A1 (ko)
DK (1) DK170778A (ko)
ES (1) ES469426A1 (ko)
FR (1) FR2389626B1 (ko)
GB (1) GB1604275A (ko)
IE (1) IE46873B1 (ko)
IT (1) IT1104190B (ko)
LU (1) LU79598A1 (ko)
NL (1) NL7804229A (ko)
SE (1) SE436569B (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT73791B (en) * 1980-10-17 1983-10-14 Merck & Co Inc Process for preparing 2-carbamimidoyl-6-substituted-1- -carbadethiapen-2-em-3-carboxylic acids

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics
AU512383B2 (en) * 1975-11-21 1980-10-09 Merck & Co., Inc. Thinenamycin derivatives

Also Published As

Publication number Publication date
IE780849L (en) 1978-11-05
FR2389626B1 (ko) 1980-06-20
DE2819453C2 (ko) 1993-02-25
SE7804447L (sv) 1978-11-06
JPH0260678B2 (ko) 1990-12-17
ES469426A1 (es) 1980-02-01
IT1104190B (it) 1985-10-21
DE2819453A1 (de) 1978-11-09
JPS53137993A (en) 1978-12-01
IE46873B1 (en) 1983-10-19
LU79598A1 (fr) 1979-02-02
FR2389626A1 (ko) 1978-12-01
BE866661A (fr) 1978-11-03
NL7804229A (nl) 1978-11-07
GB1604275A (en) 1981-12-09
DK170778A (da) 1979-01-15
IT7849176A0 (it) 1978-05-03
SE436569B (sv) 1985-01-07

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Legal Events

Date Code Title Description
PL Patent ceased