SE436569B - Analogiforfarande for framstellning av tienamycinderivat - Google Patents

Analogiforfarande for framstellning av tienamycinderivat

Info

Publication number
SE436569B
SE436569B SE7804447A SE7804447A SE436569B SE 436569 B SE436569 B SE 436569B SE 7804447 A SE7804447 A SE 7804447A SE 7804447 A SE7804447 A SE 7804447A SE 436569 B SE436569 B SE 436569B
Authority
SE
Sweden
Prior art keywords
methyl
solution
preparation
thienamycin
compound
Prior art date
Application number
SE7804447A
Other languages
English (en)
Swedish (sv)
Other versions
SE7804447L (sv
Inventor
B G Christensen
W J Leanza
K J Wildonger
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of SE7804447L publication Critical patent/SE7804447L/xx
Publication of SE436569B publication Critical patent/SE436569B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
SE7804447A 1977-05-05 1978-04-19 Analogiforfarande for framstellning av tienamycinderivat SE436569B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79397577A 1977-05-05 1977-05-05

Publications (2)

Publication Number Publication Date
SE7804447L SE7804447L (sv) 1978-11-06
SE436569B true SE436569B (sv) 1985-01-07

Family

ID=25161306

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7804447A SE436569B (sv) 1977-05-05 1978-04-19 Analogiforfarande for framstellning av tienamycinderivat

Country Status (13)

Country Link
JP (1) JPS53137993A (ko)
BE (1) BE866661A (ko)
CH (1) CH637962A5 (ko)
DE (1) DE2819453A1 (ko)
DK (1) DK170778A (ko)
ES (1) ES469426A1 (ko)
FR (1) FR2389626B1 (ko)
GB (1) GB1604275A (ko)
IE (1) IE46873B1 (ko)
IT (1) IT1104190B (ko)
LU (1) LU79598A1 (ko)
NL (1) NL7804229A (ko)
SE (1) SE436569B (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT73791B (en) * 1980-10-17 1983-10-14 Merck & Co Inc Process for preparing 2-carbamimidoyl-6-substituted-1- -carbadethiapen-2-em-3-carboxylic acids

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics
AU512383B2 (en) * 1975-11-21 1980-10-09 Merck & Co., Inc. Thinenamycin derivatives

Also Published As

Publication number Publication date
CH637962A5 (en) 1983-08-31
ES469426A1 (es) 1980-02-01
JPS53137993A (en) 1978-12-01
IT1104190B (it) 1985-10-21
DK170778A (da) 1979-01-15
FR2389626B1 (ko) 1980-06-20
FR2389626A1 (ko) 1978-12-01
GB1604275A (en) 1981-12-09
DE2819453C2 (ko) 1993-02-25
DE2819453A1 (de) 1978-11-09
BE866661A (fr) 1978-11-03
IE780849L (en) 1978-11-05
LU79598A1 (fr) 1979-02-02
JPH0260678B2 (ko) 1990-12-17
IE46873B1 (en) 1983-10-19
SE7804447L (sv) 1978-11-06
NL7804229A (nl) 1978-11-07
IT7849176A0 (it) 1978-05-03

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