ES469426A1 - Un procedimiento para la preparacion de derivados n-al- quil-n-iminometilicos de tienamicina - Google Patents
Un procedimiento para la preparacion de derivados n-al- quil-n-iminometilicos de tienamicinaInfo
- Publication number
- ES469426A1 ES469426A1 ES469426A ES469426A ES469426A1 ES 469426 A1 ES469426 A1 ES 469426A1 ES 469426 A ES469426 A ES 469426A ES 469426 A ES469426 A ES 469426A ES 469426 A1 ES469426 A1 ES 469426A1
- Authority
- ES
- Spain
- Prior art keywords
- thienamycin
- thienamycin derivatives
- derivatives
- coxr
- antibiotics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/72—Hydrazones
Abstract
Se describen derivados N-alquil-N-iminometílicos de tienamicina que pueden ser representados por la siguientes fórmula estructural **fórmula** donde R5 es , entre otros, alquilo, alquenilo, arilo o aralquilo, R6 está seleccionado entre R, OR, SR y NR1R2 donde R es, entre otros, hidrógeno o los suguiente radicales sutituidos o no sustituidos, alquilo, alquenilo, alquinilo, cicloalquilo, cicloalquilalquilo, arilo, aralquilo, heteroarilo, heteroaralquilo, heterociclico y heterociclilalquilo y R1 y R2 son hidrógeno o R. Estos compuestos, incluidos sus derivados O y carboxílicos, son útiles como antibióticos, También se describen procedimientos para la preparación de estos compuestos, composiciones farmacéuticas que contienen estos compuestos y métodos de tratamiento que consisten en administrar estos compuestos y composiciones cuando está indicado un efecto antibiótico.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79397577A | 1977-05-05 | 1977-05-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES469426A1 true ES469426A1 (es) | 1980-02-01 |
Family
ID=25161306
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES469426A Expired ES469426A1 (es) | 1977-05-05 | 1978-05-03 | Un procedimiento para la preparacion de derivados n-al- quil-n-iminometilicos de tienamicina |
Country Status (13)
Country | Link |
---|---|
JP (1) | JPS53137993A (es) |
BE (1) | BE866661A (es) |
CH (1) | CH637962A5 (es) |
DE (1) | DE2819453A1 (es) |
DK (1) | DK170778A (es) |
ES (1) | ES469426A1 (es) |
FR (1) | FR2389626B1 (es) |
GB (1) | GB1604275A (es) |
IE (1) | IE46873B1 (es) |
IT (1) | IT1104190B (es) |
LU (1) | LU79598A1 (es) |
NL (1) | NL7804229A (es) |
SE (1) | SE436569B (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT73791B (en) * | 1980-10-17 | 1983-10-14 | Merck & Co Inc | Process for preparing 2-carbamimidoyl-6-substituted-1- -carbadethiapen-2-em-3-carboxylic acids |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3950357A (en) * | 1974-11-25 | 1976-04-13 | Merck & Co., Inc. | Antibiotics |
AU512383B2 (en) * | 1975-11-21 | 1980-10-09 | Merck & Co., Inc. | Thinenamycin derivatives |
-
1978
- 1978-04-19 SE SE7804447A patent/SE436569B/sv not_active IP Right Cessation
- 1978-04-19 DK DK170778A patent/DK170778A/da active IP Right Grant
- 1978-04-20 NL NL7804229A patent/NL7804229A/xx not_active Application Discontinuation
- 1978-04-28 IE IE849/78A patent/IE46873B1/en not_active IP Right Cessation
- 1978-05-03 DE DE19782819453 patent/DE2819453A1/de active Granted
- 1978-05-03 CH CH484078A patent/CH637962A5/de not_active IP Right Cessation
- 1978-05-03 BE BE187351A patent/BE866661A/xx not_active IP Right Cessation
- 1978-05-03 GB GB17440/78A patent/GB1604275A/en not_active Expired
- 1978-05-03 IT IT49176/78A patent/IT1104190B/it active
- 1978-05-03 ES ES469426A patent/ES469426A1/es not_active Expired
- 1978-05-03 FR FR7813129A patent/FR2389626B1/fr not_active Expired
- 1978-05-05 LU LU79598A patent/LU79598A1/xx unknown
- 1978-05-06 JP JP5331278A patent/JPS53137993A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
DK170778A (da) | 1979-01-15 |
FR2389626B1 (es) | 1980-06-20 |
CH637962A5 (en) | 1983-08-31 |
LU79598A1 (fr) | 1979-02-02 |
FR2389626A1 (es) | 1978-12-01 |
IT1104190B (it) | 1985-10-21 |
JPS53137993A (en) | 1978-12-01 |
IE780849L (en) | 1978-11-05 |
SE436569B (sv) | 1985-01-07 |
IT7849176A0 (it) | 1978-05-03 |
IE46873B1 (en) | 1983-10-19 |
GB1604275A (en) | 1981-12-09 |
SE7804447L (sv) | 1978-11-06 |
JPH0260678B2 (es) | 1990-12-17 |
BE866661A (fr) | 1978-11-03 |
DE2819453A1 (de) | 1978-11-09 |
DE2819453C2 (es) | 1993-02-25 |
NL7804229A (nl) | 1978-11-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES468475A1 (es) | Procedimiento para la preparacion de derivados de cefem | |
ES473451A1 (es) | Un procedimiento para la preparacion de derivados de imida- zol. | |
ES478052A1 (es) | Procedimiento para la preparacion de nuevos nitroimidazoles. | |
ES474592A1 (es) | Procedimiento para la preparacion de derivados de imidazoli-nina | |
ES8201168A1 (es) | Procedimiento para la preparacion de derivados de cefalospo-rina | |
ES476109A1 (es) | Procedimiento para la preparacion de derivados de cefalospo-rina | |
ES8200695A1 (es) | Procedimiento para la preparacion de cefalosporinas cromofo-ras | |
ES469265A1 (es) | Procedimiento para la fabricacion de derivados del acido omega-aminoacilamisulfonico | |
ES8205759A1 (es) | Un procedimiento para la preparacion de aminopropenol y pro-pano nitrilos 2 sustituidos. | |
ES480113A1 (es) | Procedimiento para la preparacion de nuevos derivados de 2- iminoimidazolidina. | |
ES466590A1 (es) | Un procedimiento para la preparacion de derivados de oxadia-zolopirimidina. | |
SE7612962L (sv) | Tienamycinderivat | |
ES469426A1 (es) | Un procedimiento para la preparacion de derivados n-al- quil-n-iminometilicos de tienamicina | |
NO872574L (no) | Fremgangsmte for fremstilling av terapeutisk aktive tetrahydro-benzotiazoler. | |
DE3461378D1 (en) | Rifamycins derivatives and preparation and pharmaceutical compositions thereof | |
ES449068A1 (es) | Procedimiento para preparar derivados de isoxazol. | |
IE791930L (en) | Cyclohexadienes. | |
ES439261A1 (es) | Procedimiento para preparar acido 5-(2-hidroxi-n-propoxi)-4-oxo-8-n-propil-4h-1-benzopiran-2-carboxilico. | |
IE43872L (en) | 2,9-dioxatricyclo [4.3.1.0(3,7)] decanes | |
ES430676A1 (es) | Procedimiento para la preparacion de 1,2,4-tiadiazolo- (2,3-a) bencimidazoles-2-sustituidos. | |
SE7707366L (sv) | Forfarande for framstellning av 7alfa-metoxi-cefalosporansyraderivat | |
ES474052A1 (es) | Procedimiento para la obtencion de 1,4-dihidropiridazinas 1-n-sustituidas. | |
IE38745B1 (en) | 1-alkylideneaminouracils process for their preparation and their use as herbicides | |
ES471365A1 (es) | Un procedimiento para la preparacion de derivados de 3-(4- bromofenil)-3-(3-piridil)-alilamina terapeuticamente activos | |
ES8206544A1 (es) | Procedimiento para la preparacion de 4-carbamoiloxi-oxaza- fosforinas |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19980202 |