CH634993A5 - Process for the preparation of an agent for the prophylaxis and therapy of gastroenteritis - Google Patents
Process for the preparation of an agent for the prophylaxis and therapy of gastroenteritis Download PDFInfo
- Publication number
- CH634993A5 CH634993A5 CH451477A CH451477A CH634993A5 CH 634993 A5 CH634993 A5 CH 634993A5 CH 451477 A CH451477 A CH 451477A CH 451477 A CH451477 A CH 451477A CH 634993 A5 CH634993 A5 CH 634993A5
- Authority
- CH
- Switzerland
- Prior art keywords
- preparation
- agent
- rotavirus
- animals
- prophylaxis
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title claims description 15
- 238000000034 method Methods 0.000 title claims description 8
- 208000005577 Gastroenteritis Diseases 0.000 title claims description 6
- 238000011321 prophylaxis Methods 0.000 title claims description 5
- 238000002560 therapeutic procedure Methods 0.000 title claims description 5
- 241000700605 Viruses Species 0.000 claims description 14
- 206010012735 Diarrhoea Diseases 0.000 claims description 8
- 241000282849 Ruminantia Species 0.000 claims description 8
- 235000013336 milk Nutrition 0.000 claims description 6
- 210000004080 milk Anatomy 0.000 claims description 6
- 239000008267 milk Substances 0.000 claims description 6
- 241000288906 Primates Species 0.000 claims description 4
- 244000309466 calf Species 0.000 claims description 4
- 241001465754 Metazoa Species 0.000 description 17
- 241000702670 Rotavirus Species 0.000 description 14
- 241001506128 Bovine rotavirus strain NCDV/G6 Species 0.000 description 12
- 108010044091 Globulins Proteins 0.000 description 6
- 102000006395 Globulins Human genes 0.000 description 6
- 239000000427 antigen Substances 0.000 description 6
- 102000036639 antigens Human genes 0.000 description 6
- 108091007433 antigens Proteins 0.000 description 6
- 208000037951 infantile gastroenteritis Diseases 0.000 description 6
- 108060003951 Immunoglobulin Proteins 0.000 description 5
- 235000021277 colostrum Nutrition 0.000 description 5
- 210000003022 colostrum Anatomy 0.000 description 5
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 102000018358 immunoglobulin Human genes 0.000 description 5
- 241000282693 Cercopithecidae Species 0.000 description 4
- 210000000481 breast Anatomy 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 108010074605 gamma-Globulins Proteins 0.000 description 4
- 230000003053 immunization Effects 0.000 description 4
- 208000015181 infectious disease Diseases 0.000 description 4
- 244000052769 pathogen Species 0.000 description 4
- 230000001850 reproductive effect Effects 0.000 description 4
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- 238000002649 immunization Methods 0.000 description 3
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
- 230000000840 anti-viral effect Effects 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- 230000002779 inactivation Effects 0.000 description 2
- 230000002458 infectious effect Effects 0.000 description 2
- 210000003292 kidney cell Anatomy 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000003248 secreting effect Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 241000283690 Bos taurus Species 0.000 description 1
- 206010017918 Gastroenteritis viral Diseases 0.000 description 1
- 239000004471 Glycine Substances 0.000 description 1
- 241000282553 Macaca Species 0.000 description 1
- 241000702259 Orbivirus Species 0.000 description 1
- 241000606651 Rickettsiales Species 0.000 description 1
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 1
- 230000010530 Virus Neutralization Effects 0.000 description 1
- 239000005862 Whey Substances 0.000 description 1
- 102000007544 Whey Proteins Human genes 0.000 description 1
- 108010046377 Whey Proteins Proteins 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 238000012870 ammonium sulfate precipitation Methods 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- VEZXCJBBBCKRPI-UHFFFAOYSA-N beta-propiolactone Chemical compound O=C1CCO1 VEZXCJBBBCKRPI-UHFFFAOYSA-N 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 239000012228 culture supernatant Substances 0.000 description 1
- 231100000676 disease causative agent Toxicity 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 238000000703 high-speed centrifugation Methods 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 239000012678 infectious agent Substances 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000006651 lactation Effects 0.000 description 1
- 238000000464 low-speed centrifugation Methods 0.000 description 1
- 230000001926 lymphatic effect Effects 0.000 description 1
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 description 1
- 229910000021 magnesium carbonate Inorganic materials 0.000 description 1
- 239000001095 magnesium carbonate Substances 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 230000000069 prophylactic effect Effects 0.000 description 1
- 229960000380 propiolactone Drugs 0.000 description 1
- 229940124272 protein stabilizer Drugs 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 230000000405 serological effect Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 238000005199 ultracentrifugation Methods 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2616406A DE2616406B2 (de) | 1976-04-14 | 1976-04-14 | Mittel zur Prophylaxe und Therapie der Gastro-Enteritis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH634993A5 true CH634993A5 (en) | 1983-03-15 |
Family
ID=5975367
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH451477A CH634993A5 (en) | 1976-04-14 | 1977-04-12 | Process for the preparation of an agent for the prophylaxis and therapy of gastroenteritis |
Country Status (24)
| Country | Link |
|---|---|
| JP (1) | JPS52125621A (en18) |
| AR (1) | AR211891A1 (en18) |
| AT (1) | AT360644B (en18) |
| AU (1) | AU523590B2 (en18) |
| BE (1) | BE853603A (en18) |
| CA (1) | CA1092974A (en18) |
| CH (1) | CH634993A5 (en18) |
| DE (1) | DE2616406B2 (en18) |
| DK (1) | DK162777A (en18) |
| ES (1) | ES457602A1 (en18) |
| FI (1) | FI61406C (en18) |
| FR (1) | FR2347934A1 (en18) |
| GB (1) | GB1560344A (en18) |
| IE (1) | IE44814B1 (en18) |
| IL (1) | IL51863A (en18) |
| IT (1) | IT1075316B (en18) |
| LU (1) | LU77104A1 (en18) |
| NL (1) | NL7703879A (en18) |
| NO (1) | NO771289L (en18) |
| NZ (1) | NZ183842A (en18) |
| PT (1) | PT66433A (en18) |
| SE (1) | SE7704245L (en18) |
| YU (1) | YU96877A (en18) |
| ZA (1) | ZA772237B (en18) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4341763A (en) | 1981-03-10 | 1982-07-27 | Smithkline-Rit | Methods of vaccinating humans against rotavirus infection |
| JPS58154513A (ja) * | 1982-03-09 | 1983-09-14 | Sendai Biseibutsu Kenkyusho | 予防及び治療薬 |
| JPH0813755B2 (ja) * | 1988-04-13 | 1996-02-14 | 太陽化学株式会社 | ウイルス性下痢症予防剤 |
| US6291228B1 (en) | 1988-08-03 | 2001-09-18 | Vericore Limited | Vaccine |
| AU5254790A (en) * | 1989-04-06 | 1990-10-11 | Chugai Seiyaku Kabushiki Kaisha | Process for preparing a therapeutic agent for rotavirus infection |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3304952A (en) * | 1965-03-15 | 1967-02-21 | William A Knapp Company | Vent control device |
-
1976
- 1976-04-14 DE DE2616406A patent/DE2616406B2/de not_active Withdrawn
-
1977
- 1977-04-06 ES ES457602A patent/ES457602A1/es not_active Expired
- 1977-04-07 NL NL7703879A patent/NL7703879A/xx not_active Application Discontinuation
- 1977-04-12 AR AR267176A patent/AR211891A1/es active
- 1977-04-12 FI FI771143A patent/FI61406C/fi not_active IP Right Cessation
- 1977-04-12 CH CH451477A patent/CH634993A5/de not_active IP Right Cessation
- 1977-04-12 YU YU00968/77A patent/YU96877A/xx unknown
- 1977-04-12 IL IL51863A patent/IL51863A/xx unknown
- 1977-04-12 IT IT22363/77A patent/IT1075316B/it active
- 1977-04-12 LU LU77104A patent/LU77104A1/xx unknown
- 1977-04-13 ZA ZA00772237A patent/ZA772237B/xx unknown
- 1977-04-13 IE IE768/77A patent/IE44814B1/en unknown
- 1977-04-13 NO NO771289A patent/NO771289L/no unknown
- 1977-04-13 NZ NZ183842A patent/NZ183842A/xx unknown
- 1977-04-13 SE SE7704245A patent/SE7704245L/ not_active Application Discontinuation
- 1977-04-13 PT PT66433A patent/PT66433A/pt unknown
- 1977-04-13 DK DK162777A patent/DK162777A/da not_active IP Right Cessation
- 1977-04-13 CA CA276,080A patent/CA1092974A/en not_active Expired
- 1977-04-13 AT AT257277A patent/AT360644B/de not_active IP Right Cessation
- 1977-04-13 AU AU24206/77A patent/AU523590B2/en not_active Expired
- 1977-04-14 GB GB15618/77A patent/GB1560344A/en not_active Expired
- 1977-04-14 JP JP4212877A patent/JPS52125621A/ja active Pending
- 1977-04-14 BE BE176722A patent/BE853603A/xx not_active IP Right Cessation
- 1977-04-14 FR FR7711217A patent/FR2347934A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ES457602A1 (es) | 1978-08-16 |
| GB1560344A (en) | 1980-02-06 |
| FI61406C (fi) | 1982-08-10 |
| ZA772237B (en) | 1978-03-29 |
| YU96877A (en) | 1984-02-29 |
| NO771289L (no) | 1977-10-17 |
| IL51863A0 (en) | 1977-06-30 |
| IT1075316B (it) | 1985-04-22 |
| AT360644B (de) | 1981-01-26 |
| SE7704245L (sv) | 1977-10-15 |
| LU77104A1 (en18) | 1977-11-14 |
| DE2616406A1 (de) | 1977-10-20 |
| FI61406B (fi) | 1982-04-30 |
| FR2347934B1 (en18) | 1980-03-07 |
| AU523590B2 (en) | 1982-08-05 |
| PT66433A (de) | 1977-05-01 |
| AU2420677A (en) | 1978-10-19 |
| BE853603A (fr) | 1977-10-14 |
| IL51863A (en) | 1980-07-31 |
| DE2616406B2 (de) | 1980-08-07 |
| NZ183842A (en) | 1980-03-05 |
| NL7703879A (nl) | 1977-10-18 |
| FI771143A (en18) | 1977-10-15 |
| CA1092974A (en) | 1981-01-06 |
| FR2347934A1 (fr) | 1977-11-10 |
| AR211891A1 (es) | 1978-03-31 |
| ATA257277A (de) | 1980-06-15 |
| IE44814L (en) | 1977-10-14 |
| IE44814B1 (en) | 1982-04-07 |
| DK162777A (da) | 1977-10-15 |
| JPS52125621A (en) | 1977-10-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US3376198A (en) | Method of producing antibodies in milk | |
| DE3689717T2 (de) | Einen spezifischen Antikörper enthaltender Stoff aus Eiern, Verfahren zu dessen Herstellung und seine Anwendung. | |
| DE3504221C2 (de) | Mittel zur passiven Immunisierung von Säugern | |
| DE69934179T2 (de) | Zusammensetzung enthaltend ein Antigen, ein TH-1 induzierendes Adjuvans und eine im Wasser schwer lösliche Aminosäure zur Verwendung in der Immunisierung | |
| DE69834490T2 (de) | Verfahren zur herstellung von immunoglobulin a in milch | |
| DE2542792A1 (de) | Verfahren zur erhoehung der antikoerpermenge in der milch von milchabsondernden rindern | |
| JPH08508718A (ja) | ワクチン組成物および全身的ワクチン接種による粘膜性免疫応答誘導方法 | |
| DE3701066C2 (de) | Intravenös injizierbares Immunglobulin mit hohem Antikörpertiter gegenüber dem respiratorischen Syncytialvirus, Verfahren zu dessen Herstellung und pharmazeutische Zubereitung, welche dieses enthält | |
| EP3184120B1 (en) | Emulsified vaccine to obtain formulations of concentrated igy immunoglobulins; processes and uses for the same. | |
| JPH0753669B2 (ja) | 鶏卵からの特異的抗体含有材料およびその製造方法と用途 | |
| US5807551A (en) | Method to provide artificial passive immunity in birds | |
| US4171354A (en) | Vaccine for animal respiratory diseases | |
| DE2817299A1 (de) | Verfahren zur herstellung eines attenuierten infektioese-gastroenteritis (tge)-virusstammes zur anwendung in lebendvakzinen | |
| CH634993A5 (en) | Process for the preparation of an agent for the prophylaxis and therapy of gastroenteritis | |
| DE1924304C3 (de) | Diäthylaminoäthyldextran (DEAE-D) als Adjuvans für Impfstoffe zur aktiven Immunisierung von Säugetieren | |
| DE69333588T2 (de) | Verfahren zur verstärkung zellularer immunantworten | |
| DE602004005963T2 (de) | Verwendung von vogelantikörpern | |
| DE2538994A1 (de) | Bakterieller impfstoff und verfahren zu seiner herstellung | |
| Milner et al. | Pathogenesis of in utero infections with abortogenic and non-abortogenic alphaviruses in mice | |
| US3423505A (en) | Rabies vaccine and process for preparation thereof | |
| Chidlow et al. | The role of oral immunisation in stimulating Escherichia coli antibody of the IgM class in porcine colostrum | |
| US3962422A (en) | Method for immunizing nursing piglets against transmissible gastroenteritis(TGE) virus | |
| WO2000052055A1 (de) | SPEZIFISCHE IgY-EIDOTTERANTIKÖRPER, IHRE GEWINNUNG UND IHRE VERWENDUNG | |
| DE60025945T2 (de) | Herstellung von antikörpern in mammarsekreten von zuchttieren | |
| 村上敏明 et al. | Protective effect of orally administered immunoglobulins against experimental calf diarrhea. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |