CH634069A5 - Process for preparing novel 7-substituted 7H-pyrrolo[3,2-f]quinazoline-1,3-diamines - Google Patents

Process for preparing novel 7-substituted 7H-pyrrolo[3,2-f]quinazoline-1,3-diamines Download PDF

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Publication number
CH634069A5
CH634069A5 CH850677A CH850677A CH634069A5 CH 634069 A5 CH634069 A5 CH 634069A5 CH 850677 A CH850677 A CH 850677A CH 850677 A CH850677 A CH 850677A CH 634069 A5 CH634069 A5 CH 634069A5
Authority
CH
Switzerland
Prior art keywords
methyl
phenyl
quinolinyl
pyrrolo
pyridinyl
Prior art date
Application number
CH850677A
Other languages
German (de)
English (en)
Inventor
Kurt Willi Ledig
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Priority to CH289482A priority Critical patent/CH636616A5/de
Priority to CH289382A priority patent/CH635842A5/de
Publication of CH634069A5 publication Critical patent/CH634069A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH850677A 1976-07-09 1977-07-08 Process for preparing novel 7-substituted 7H-pyrrolo[3,2-f]quinazoline-1,3-diamines CH634069A5 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CH289482A CH636616A5 (en) 1976-07-09 1982-05-10 Process for preparing 7-substituted 7H-pyrrolo[3,2-f]quinazoline-1,3-diamines
CH289382A CH635842A5 (en) 1976-07-09 1982-05-10 Process for preparing novel 7H-pyrrolo[3,2-f]quinazoline-1,3-diamines

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US70400276A 1976-07-09 1976-07-09
US70400176A 1976-07-09 1976-07-09
GB5382176 1976-12-23
US78498777A 1977-04-06 1977-04-06

Publications (1)

Publication Number Publication Date
CH634069A5 true CH634069A5 (en) 1983-01-14

Family

ID=27449036

Family Applications (1)

Application Number Title Priority Date Filing Date
CH850677A CH634069A5 (en) 1976-07-09 1977-07-08 Process for preparing novel 7-substituted 7H-pyrrolo[3,2-f]quinazoline-1,3-diamines

Country Status (13)

Country Link
JP (1) JPS539796A (da)
AU (1) AU507828B2 (da)
BE (1) BE856647A (da)
CA (1) CA1093555A (da)
CH (1) CH634069A5 (da)
DE (1) DE2731039A1 (da)
DK (1) DK309977A (da)
FR (1) FR2357563A1 (da)
IE (1) IE45427B1 (da)
IN (1) IN147488B (da)
MX (1) MX5133E (da)
NL (1) NL7707658A (da)
PH (1) PH13539A (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0639075A1 (en) * 1990-11-14 1995-02-22 Chiron Corporation Specific inhibition of dihydrofolate reductase and compounds therefor
KR100810468B1 (ko) * 2001-10-10 2008-03-07 씨제이제일제당 (주) 사이클로옥시게나제-2의 저해제로서 선택성이 뛰어난1ｈ-인돌 유도체
US7262297B2 (en) * 2003-05-15 2007-08-28 Hoffmann-La Roche Inc. Diaminopyrroloquinazolines compounds as protein tyrosine phosphatase inhibitors
US11077109B2 (en) * 2017-08-01 2021-08-03 The Trustees Of Princeton University Compounds having antibacterial activity and methods of use

Also Published As

Publication number Publication date
DK309977A (da) 1978-01-10
FR2357563B1 (da) 1983-03-11
IN147488B (da) 1980-03-15
PH13539A (en) 1980-06-26
CA1093555A (en) 1981-01-13
IE45427B1 (en) 1982-08-25
MX5133E (es) 1983-03-28
IE45427L (en) 1978-10-06
JPS6254111B2 (da) 1987-11-13
FR2357563A1 (fr) 1978-02-03
JPS539796A (en) 1978-01-28
BE856647A (fr) 1978-01-09
AU2668777A (en) 1979-01-04
NL7707658A (nl) 1978-01-11
DE2731039A1 (de) 1978-01-19
AU507828B2 (en) 1980-02-28

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