CH633796A5 - Dipyridoindoles therapeutiquement actifs. - Google Patents

Dipyridoindoles therapeutiquement actifs. Download PDF

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Publication number
CH633796A5
CH633796A5 CH391878A CH391878A CH633796A5 CH 633796 A5 CH633796 A5 CH 633796A5 CH 391878 A CH391878 A CH 391878A CH 391878 A CH391878 A CH 391878A CH 633796 A5 CH633796 A5 CH 633796A5
Authority
CH
Switzerland
Prior art keywords
compound
formula
group
methyl
amino
Prior art date
Application number
CH391878A
Other languages
English (en)
French (fr)
Inventor
Emile Bisagni
Claire Ducrocq
Christian Rivalle
Pierre Tambourin
Francoise Wendling
Jean-Claude Chermann
Luc Montagnier
Original Assignee
Anvar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anvar filed Critical Anvar
Publication of CH633796A5 publication Critical patent/CH633796A5/fr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/44Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by —CHO groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00Compounds containing azido groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
CH391878A 1977-04-13 1978-04-12 Dipyridoindoles therapeutiquement actifs. CH633796A5 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7711148A FR2387229A1 (fr) 1977-04-13 1977-04-13 Dipyrido (4,3-b) (3,4-f) indoles, procede d'obtention, application therapeutique et compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
CH633796A5 true CH633796A5 (fr) 1982-12-31

Family

ID=9189361

Family Applications (1)

Application Number Title Priority Date Filing Date
CH391878A CH633796A5 (fr) 1977-04-13 1978-04-12 Dipyridoindoles therapeutiquement actifs.

Country Status (12)

Country Link
US (2) US4266060A (US20110232667A1-20110929-C00004.png)
JP (1) JPS549299A (US20110232667A1-20110929-C00004.png)
BE (1) BE865851A (US20110232667A1-20110929-C00004.png)
CA (1) CA1117945A (US20110232667A1-20110929-C00004.png)
CH (1) CH633796A5 (US20110232667A1-20110929-C00004.png)
DE (1) DE2815724A1 (US20110232667A1-20110929-C00004.png)
ES (1) ES468721A1 (US20110232667A1-20110929-C00004.png)
FR (1) FR2387229A1 (US20110232667A1-20110929-C00004.png)
GB (1) GB1603228A (US20110232667A1-20110929-C00004.png)
IT (1) IT1095582B (US20110232667A1-20110929-C00004.png)
LU (1) LU79422A1 (US20110232667A1-20110929-C00004.png)
NL (1) NL184895C (US20110232667A1-20110929-C00004.png)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4334070A (en) * 1980-12-15 1982-06-08 Hoffmann-La Roche Inc. Cycloalka[4,5]pyrrolo[2,3-g]isoquinolines
DK158666C (da) * 1982-11-04 1990-11-19 Glaxo Group Ltd Analogifremgangsmaade til fremstilling af 5,14-dihydrobenz-oe5,6aa-isoindolooe2,1-baa-isoquinolin-8,13-dion
NZ211960A (en) * 1984-05-03 1989-05-29 Glaxo Group Ltd Benz(5,6)isoindolo(2,1-b)isoquinoline-8,13-dione derivatives and pharmaceutical compositions
JPH0642591B2 (ja) * 1984-11-30 1994-06-01 ミノルタカメラ株式会社 プリント配線基板の製造方法
NO872963L (no) * 1986-07-29 1988-02-01 Glaxo Group Ltd Isokinolinderivater.
DK616087A (da) * 1986-11-27 1988-05-28 Glaxo Group Ltd Isoquinolinderivater og farmaceutiske praeparater indeholdende dem
GB8800312D0 (en) * 1988-01-07 1988-02-10 Glaxo Group Ltd Process
FR2627493B1 (fr) * 1988-02-23 1991-10-31 Sanofi Sa Procede de preparation de derives d'isoquinoleine
FR2645861A1 (fr) * 1989-04-17 1990-10-19 Inst Nat Sante Rech Med Utilisation de dipyrido (4,3-b) (3,4-f) indoles pour la preparation de medicaments utiles pour le traitement du sida
US5281608A (en) * 1992-08-28 1994-01-25 American Home Products Corporation Substituted tetrahydropyrido[3',4':4,5]-pyrrolo[3,2-c]quinolines
FR2859474B1 (fr) * 2003-09-04 2006-01-13 Centre Nat Rech Scient Utilisation de composes derives d'indole pour la preparation d'un medicament utile pour le traitement de maladies genetiques resultant de l'alteration des processus d'epissage
GEP20084439B (en) * 2004-01-23 2008-07-25 Amgen Inc Nitrogen-containing heterocyclic derivatives and pharmaceutical use thereof
CN104844510B (zh) 2009-06-12 2019-04-23 Abivax公司 用于治疗过早衰老和尤其是早衰的化合物
US10253020B2 (en) 2009-06-12 2019-04-09 Abivax Compounds for preventing, inhibiting, or treating cancer, AIDS and/or premature aging
EP2266972A1 (en) * 2009-06-12 2010-12-29 Splicos New chemical molecules that inhibit the splicing mechanism for treating diseases resulting from splicing anomalies
EP2465502A1 (en) 2010-12-15 2012-06-20 Société Splicos Compounds useful for treating AIDS
EP2757161A1 (en) 2013-01-17 2014-07-23 Splicos miRNA-124 as a biomarker of viral infection
CN105530938B (zh) 2013-07-05 2019-10-22 Abivax公司 用于治疗由逆转录病毒引起的疾病的化合物
EP2974729A1 (en) 2014-07-17 2016-01-20 Abivax Quinoline derivatives for use in the treatment of inflammatory diseases
EP3669873A1 (en) 2018-12-20 2020-06-24 Abivax Quinoline derivatives for use ine the traeatment of inflammation diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2248828B1 (US20110232667A1-20110929-C00004.png) * 1973-10-29 1977-04-15 Anvar
US3933827A (en) * 1974-10-29 1976-01-20 Hoffmann-La Roche Inc. 9-Acyloxy-5,11-dimethyl-6H-pyrido[4,3-B]carbazoles

Also Published As

Publication number Publication date
JPS6225670B2 (US20110232667A1-20110929-C00004.png) 1987-06-04
ES468721A1 (es) 1978-12-16
DE2815724C2 (US20110232667A1-20110929-C00004.png) 1991-02-14
CA1117945A (en) 1982-02-09
IT1095582B (it) 1985-08-10
US4266060A (en) 1981-05-05
JPS549299A (en) 1979-01-24
DE2815724A1 (de) 1978-10-26
FR2387229A1 (fr) 1978-11-10
NL184895B (nl) 1989-07-03
US4444776A (en) 1984-04-24
BE865851A (fr) 1978-10-10
NL184895C (nl) 1989-12-01
GB1603228A (en) 1981-11-18
LU79422A1 (fr) 1979-11-07
FR2387229B1 (US20110232667A1-20110929-C00004.png) 1980-05-09
IT7822254A0 (it) 1978-04-12
NL7803951A (nl) 1978-10-17

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PL Patent ceased