ES468721A1 - Procedimiento para obtener dipirido (4,3-b) (3,4-f) indoles. - Google Patents

Procedimiento para obtener dipirido (4,3-b) (3,4-f) indoles.

Info

Publication number
ES468721A1
ES468721A1 ES468721A ES468721A ES468721A1 ES 468721 A1 ES468721 A1 ES 468721A1 ES 468721 A ES468721 A ES 468721A ES 468721 A ES468721 A ES 468721A ES 468721 A1 ES468721 A1 ES 468721A1
Authority
ES
Spain
Prior art keywords
dipyrido
indoles
obtaining
alkyl group
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES468721A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bpifrance Financement SA
Original Assignee
Agence National de Valorisation de la Recherche ANVAR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agence National de Valorisation de la Recherche ANVAR filed Critical Agence National de Valorisation de la Recherche ANVAR
Publication of ES468721A1 publication Critical patent/ES468721A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/44—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by —CHO groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

Procedimiento para obtener dipirido [4,3-b][3,4-f]indoles, que responden a la fórmula: **(Fórmula)** En la que R¿1 es hidrógeno, el grupo hidroxi, un grupo alcohilo, de preferencia inferior, alcohiltio o alcoxilo, un halógeno o un grupo amino; R¿2 es hidrógeno o un grupo alcohilo inferior, de preferencia un grupo metilo, y las sales de estos aceptables en farmacia.
ES468721A 1977-04-13 1978-04-12 Procedimiento para obtener dipirido (4,3-b) (3,4-f) indoles. Expired ES468721A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7711148A FR2387229A1 (fr) 1977-04-13 1977-04-13 Dipyrido (4,3-b) (3,4-f) indoles, procede d'obtention, application therapeutique et compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
ES468721A1 true ES468721A1 (es) 1978-12-16

Family

ID=9189361

Family Applications (1)

Application Number Title Priority Date Filing Date
ES468721A Expired ES468721A1 (es) 1977-04-13 1978-04-12 Procedimiento para obtener dipirido (4,3-b) (3,4-f) indoles.

Country Status (12)

Country Link
US (2) US4266060A (es)
JP (1) JPS549299A (es)
BE (1) BE865851A (es)
CA (1) CA1117945A (es)
CH (1) CH633796A5 (es)
DE (1) DE2815724A1 (es)
ES (1) ES468721A1 (es)
FR (1) FR2387229A1 (es)
GB (1) GB1603228A (es)
IT (1) IT1095582B (es)
LU (1) LU79422A1 (es)
NL (1) NL184895C (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4334070A (en) * 1980-12-15 1982-06-08 Hoffmann-La Roche Inc. Cycloalka[4,5]pyrrolo[2,3-g]isoquinolines
DK158666C (da) * 1982-11-04 1990-11-19 Glaxo Group Ltd Analogifremgangsmaade til fremstilling af 5,14-dihydrobenz-oe5,6aa-isoindolooe2,1-baa-isoquinolin-8,13-dion
EP0161102B1 (en) * 1984-05-03 1990-02-21 Glaxo Group Limited Isoquinoline derivatives
JPH0642591B2 (ja) * 1984-11-30 1994-06-01 ミノルタカメラ株式会社 プリント配線基板の製造方法
NO872963L (no) * 1986-07-29 1988-02-01 Glaxo Group Ltd Isokinolinderivater.
DK616087A (da) * 1986-11-27 1988-05-28 Glaxo Group Ltd Isoquinolinderivater og farmaceutiske praeparater indeholdende dem
GB8800312D0 (en) * 1988-01-07 1988-02-10 Glaxo Group Ltd Process
FR2627493B1 (fr) * 1988-02-23 1991-10-31 Sanofi Sa Procede de preparation de derives d'isoquinoleine
FR2645861A1 (fr) * 1989-04-17 1990-10-19 Inst Nat Sante Rech Med Utilisation de dipyrido (4,3-b) (3,4-f) indoles pour la preparation de medicaments utiles pour le traitement du sida
US5281608A (en) * 1992-08-28 1994-01-25 American Home Products Corporation Substituted tetrahydropyrido[3',4':4,5]-pyrrolo[3,2-c]quinolines
FR2859474B1 (fr) * 2003-09-04 2006-01-13 Centre Nat Rech Scient Utilisation de composes derives d'indole pour la preparation d'un medicament utile pour le traitement de maladies genetiques resultant de l'alteration des processus d'epissage
CN1933839A (zh) * 2004-01-23 2007-03-21 安进公司 化合物和使用方法
KR101982461B1 (ko) 2009-06-12 2019-05-24 아비박스 조기 노화, 구체적으로 조로증을 치료하는데 유용한 화합물
US10253020B2 (en) 2009-06-12 2019-04-09 Abivax Compounds for preventing, inhibiting, or treating cancer, AIDS and/or premature aging
EP2266972A1 (en) * 2009-06-12 2010-12-29 Splicos New chemical molecules that inhibit the splicing mechanism for treating diseases resulting from splicing anomalies
EP2465502A1 (en) 2010-12-15 2012-06-20 Société Splicos Compounds useful for treating AIDS
EP2757161A1 (en) 2013-01-17 2014-07-23 Splicos miRNA-124 as a biomarker of viral infection
HRP20211839T1 (hr) 2013-07-05 2022-03-04 Abivax Biciklički spojevi korisni za liječenje bolesti uzrokovanih retrovirusima
EP2974729A1 (en) 2014-07-17 2016-01-20 Abivax Quinoline derivatives for use in the treatment of inflammatory diseases
EP3669873A1 (en) 2018-12-20 2020-06-24 Abivax Quinoline derivatives for use ine the traeatment of inflammation diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2248828B1 (es) * 1973-10-29 1977-04-15 Anvar
US3933827A (en) * 1974-10-29 1976-01-20 Hoffmann-La Roche Inc. 9-Acyloxy-5,11-dimethyl-6H-pyrido[4,3-B]carbazoles

Also Published As

Publication number Publication date
US4266060A (en) 1981-05-05
IT1095582B (it) 1985-08-10
FR2387229B1 (es) 1980-05-09
DE2815724C2 (es) 1991-02-14
IT7822254A0 (it) 1978-04-12
CH633796A5 (fr) 1982-12-31
LU79422A1 (fr) 1979-11-07
FR2387229A1 (fr) 1978-11-10
GB1603228A (en) 1981-11-18
DE2815724A1 (de) 1978-10-26
BE865851A (fr) 1978-10-10
NL184895C (nl) 1989-12-01
CA1117945A (en) 1982-02-09
JPS549299A (en) 1979-01-24
JPS6225670B2 (es) 1987-06-04
US4444776A (en) 1984-04-24
NL184895B (nl) 1989-07-03
NL7803951A (nl) 1978-10-17

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19981103