CH626892A5 - - Google Patents

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Publication number
CH626892A5
CH626892A5 CH1429676A CH1429676A CH626892A5 CH 626892 A5 CH626892 A5 CH 626892A5 CH 1429676 A CH1429676 A CH 1429676A CH 1429676 A CH1429676 A CH 1429676A CH 626892 A5 CH626892 A5 CH 626892A5
Authority
CH
Switzerland
Prior art keywords
chloro
benzene
acid
methyl
benzodiazepine
Prior art date
Application number
CH1429676A
Other languages
German (de)
English (en)
Inventor
Takeshi Hara
Yasutaka Kayama
Kazuhiko Itoh
Toshiro Mori
Hitoshi Fujimori
Tamiko Sunami
Yoshinobu Hashimoto
Sachio Ishimoto
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP13520375A external-priority patent/JPS5271462A/ja
Priority claimed from JP13636575A external-priority patent/JPS5271493A/ja
Priority claimed from JP15335075A external-priority patent/JPS52102271A/ja
Priority claimed from JP275576A external-priority patent/JPS5287163A/ja
Priority claimed from JP8557376A external-priority patent/JPS5312890A/ja
Priority claimed from JP8557276A external-priority patent/JPS5312856A/ja
Priority claimed from JP10492176A external-priority patent/JPS5331657A/ja
Priority claimed from JP10622276A external-priority patent/JPS5331696A/ja
Application filed by Teijin Ltd filed Critical Teijin Ltd
Publication of CH626892A5 publication Critical patent/CH626892A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH1429676A 1975-11-12 1976-11-12 CH626892A5 (fr)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP13520375A JPS5271462A (en) 1975-11-12 1975-11-12 Process for preparing new benzophenone derivatives
JP13636575A JPS5271493A (en) 1975-11-14 1975-11-14 Synthesis of pyrrolobenzodiazepins or acid addition salts thereof
JP15335075A JPS52102271A (en) 1975-12-24 1975-12-24 Synthesis of novel benzophenone derivatives
JP275576A JPS5287163A (en) 1976-01-14 1976-01-14 Pyprolylbenzophenones
JP8557376A JPS5312890A (en) 1976-07-20 1976-07-20 Preparation of pyrrolobenzodiazepins and their acid salts
JP8557276A JPS5312856A (en) 1976-07-20 1976-07-20 Preparation of novel benzophenone derivatives
JP10492176A JPS5331657A (en) 1976-09-03 1976-09-03 Preparation of novel benzophenone derivatives
JP10622276A JPS5331696A (en) 1976-09-07 1976-09-07 Preparation of pyrrolobenzodiazepins and their acid salts

Publications (1)

Publication Number Publication Date
CH626892A5 true CH626892A5 (fr) 1981-12-15

Family

ID=27571472

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1429676A CH626892A5 (fr) 1975-11-12 1976-11-12

Country Status (5)

Country Link
US (1) US4169150A (fr)
CH (1) CH626892A5 (fr)
DE (1) DE2651809A1 (fr)
FR (1) FR2331349A1 (fr)
GB (1) GB1522118A (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4318854A (en) * 1979-02-07 1982-03-09 Hoffmann-La Roche Inc. Intermediates in the production of 2-benzazepines
US4194049A (en) * 1979-03-29 1980-03-18 Hoffmann-La Roche Inc. 2-[[2-Methyl-1-[2-benzoyl(or benzyl)phenyl]-1H-imidazol-5-yl]methyl]-1H-isoindole-1,3(2H)-diones
US4354973A (en) * 1980-08-05 1982-10-19 Hoffmann-La Roche Inc. Pyrrolo[3,4-d][2]benzazepines
US4428878A (en) 1981-07-23 1984-01-31 Hoffmann-La Roche Inc. Pyrrolo[3,4-d][2]benzazepines
US4431823A (en) * 1981-07-23 1984-02-14 Hoffmann-La Roche Inc. 1H-Pyrrole-3-carbonitrile-4(2-benzoyl)phenyl derivatives as intermediates for pyrrolo[3,4-D][2]benzazepines
US4405518A (en) * 1981-07-23 1983-09-20 Hoffmann-La Roche Inc. Pyrrolo[3,4-d] [2] benzazepines
US4428879A (en) 1981-07-23 1984-01-31 Hoffmann-La Roche Inc. Pyrrolo[3,4,-d][2]benzazepines
US4545935A (en) * 1983-09-12 1985-10-08 Iowa State University Research Foundation, Inc. Amidoalkylation reactions of anilines
EP0518484A3 (en) * 1991-05-14 1993-03-17 Merck & Co. Inc. 1,4-benzodiazepines condesed with 5- and 6-membered heterocyclic rings to treat anxiety, pain, pupil constriction, withdrawal-syndrome or oncologic disorders
ITUB20155193A1 (it) * 2015-11-03 2017-05-03 Italfarmaco Spa Sospensioni orali di Givinostat fisicamente e chimicamente stabili

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3987052A (en) * 1969-03-17 1976-10-19 The Upjohn Company 6-Phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepines
US3642820A (en) * 1969-11-03 1972-02-15 Upjohn Co 4 5-dihydropyrrolo(3 2 1-jk)(1 4)bezodiazepines
US3917627A (en) * 1971-08-04 1975-11-04 Upjohn Co 6-Substituted 4H-imidazo{8 1,2-a{9 {8 1,4{9 benzodiazepines and process for their production

Also Published As

Publication number Publication date
US4169150A (en) 1979-09-25
GB1522118A (en) 1978-08-23
FR2331349B1 (fr) 1978-11-17
FR2331349A1 (fr) 1977-06-10
DE2651809A1 (de) 1977-06-16

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