CH626075A5 - - Google Patents

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Publication number
CH626075A5
CH626075A5 CH885580A CH885580A CH626075A5 CH 626075 A5 CH626075 A5 CH 626075A5 CH 885580 A CH885580 A CH 885580A CH 885580 A CH885580 A CH 885580A CH 626075 A5 CH626075 A5 CH 626075A5
Authority
CH
Switzerland
Prior art keywords
formula
quinazoline
oxo
dihydro
carbon atoms
Prior art date
Application number
CH885580A
Other languages
German (de)
English (en)
Inventor
Gianfederico Doria
Ciriaco Romeo
Piernicola Giraldi
Francesco Lauria
Maria-Luisa Corno
Piero Sberze
Marcello Tibolla
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of CH626075A5 publication Critical patent/CH626075A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/93—Sulfur atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CH885580A 1975-12-05 1980-11-28 CH626075A5 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT29998/75A IT1050750B (it) 1975-12-05 1975-12-05 Derivati della 3.4 di idro chinazolina

Publications (1)

Publication Number Publication Date
CH626075A5 true CH626075A5 (no) 1981-10-30

Family

ID=11228830

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1527276A CH626073A5 (no) 1975-12-05 1976-12-03
CH885580A CH626075A5 (no) 1975-12-05 1980-11-28

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH1527276A CH626073A5 (no) 1975-12-05 1976-12-03

Country Status (22)

Country Link
US (1) US4251531A (no)
JP (1) JPS5271485A (no)
AT (1) AT355029B (no)
AU (1) AU505660B2 (no)
BE (1) BE848696A (no)
CA (1) CA1084051A (no)
CH (2) CH626073A5 (no)
CS (1) CS194786B2 (no)
DE (1) DE2654215A1 (no)
DK (1) DK147855C (no)
FI (1) FI64359C (no)
FR (1) FR2333511A1 (no)
GB (1) GB1523081A (no)
HU (1) HU177817B (no)
IL (1) IL50849A (no)
IT (1) IT1050750B (no)
NL (1) NL7613450A (no)
NO (1) NO146095C (no)
NZ (1) NZ182778A (no)
SE (1) SE7613588L (no)
SU (1) SU786894A3 (no)
ZA (1) ZA766745B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL69274A (en) * 1982-08-05 1986-08-31 Erba Farmitalia (substituted amino)derivatives of 3-benzylidene-pyrrolo(2,1-b)quinazolin-9-ones and 6-benzylidene-pyrido(2,1-b)quinazolin-11-ones,their preparation and pharmaceutical compositions containing them
JPS5925224U (ja) * 1982-08-10 1984-02-16 株式会社根来 かばん
US4666913A (en) * 1985-11-22 1987-05-19 William H. Rorer, Inc. Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses
GB8827988D0 (en) * 1988-11-30 1989-01-05 Smith Kline French Lab Chemical compounds
US5430148A (en) * 1992-03-31 1995-07-04 Agouron Pharmaceuticals, Inc. Antiproliferative quinazolines
WO1999061406A2 (en) * 1998-05-22 1999-12-02 Abbott Laboratories Antiangiogenic drug to treat cancer, arthritis and retinopathy
US6632961B1 (en) 1998-05-22 2003-10-14 Abbott Laboratories Antiangiogenic drug to treat cancer, arthritis and retinopathy
CO5170498A1 (es) * 1999-05-28 2002-06-27 Abbott Lab Biaril sulfonamidas son utiles como inhibidores de proliferacion celular
US7893071B2 (en) * 2001-04-23 2011-02-22 University Of Virginia Patent Foundation Synthesis and evaluation of novel phthalimide mimics as anti-angiogenic
DE602004025803D1 (de) * 2003-06-06 2010-04-15 Arexis Ab Verwendung von kondensierten heterozyklischen verbindungen als scce-hemmern zur behandlung von hautzuständen
CN100518740C (zh) * 2003-06-06 2009-07-29 阿里克斯股份公司 杂环化合物作为scce抑制剂的制药用途
EP2050739B1 (en) * 2006-08-08 2016-07-06 ASKA Pharmaceutical Co., Ltd. Quinazoline derivative
DK2118074T3 (en) 2007-02-01 2014-03-10 Resverlogix Corp Compounds for the prevention and treatment of cardiovascular diseases
NZ755378A (en) 2009-03-18 2022-07-29 Resverlogix Corp Novel quinazolinones and related compounds for use as anti-inflammatory agents
US9757368B2 (en) 2009-04-22 2017-09-12 Resverlogix Corp. Anti-inflammatory agents
CA2977308A1 (en) 2015-03-13 2016-09-22 Resverlogix Corp. Compositions and therapeutic methods for the treatment of complement-associated diseases
GB201510254D0 (en) * 2015-06-12 2015-07-29 Syngenta Participations Ag Improvements in or relating to organic compounds
CA3105174A1 (en) * 2018-06-27 2020-01-02 Reborna Biosciences, Inc. Prophylactic or therapeutic agent for spinal muscular atrophy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3696102A (en) * 1970-03-09 1972-10-03 Pfizer & Co C Process for the synthesis of substituted quinazolin-4-ones

Also Published As

Publication number Publication date
IL50849A (en) 1980-11-30
SU786894A3 (ru) 1980-12-07
BE848696A (fr) 1977-03-16
GB1523081A (en) 1978-08-31
AT355029B (de) 1980-02-11
CS194786B2 (en) 1979-12-31
FR2333511A1 (fr) 1977-07-01
DE2654215A1 (de) 1977-06-16
NL7613450A (nl) 1977-06-07
DK147855B (da) 1984-12-24
ATA894376A (de) 1979-07-15
US4251531A (en) 1981-02-17
JPS5543464B2 (no) 1980-11-06
AU505660B2 (en) 1979-11-29
NZ182778A (en) 1978-07-28
DK147855C (da) 1985-06-10
SE7613588L (sv) 1977-06-06
NO764135L (no) 1977-06-07
ZA766745B (en) 1977-10-26
HU177817B (en) 1981-12-28
IT1050750B (it) 1981-03-20
FI64359C (fi) 1983-11-10
NO146095C (no) 1982-08-11
FI763391A (no) 1977-06-06
CA1084051A (en) 1980-08-19
IL50849A0 (en) 1977-01-31
DK546776A (da) 1977-06-06
FI64359B (fi) 1983-07-29
JPS5271485A (en) 1977-06-14
NO146095B (no) 1982-04-19
FR2333511B1 (no) 1979-03-02
CH626073A5 (no) 1981-10-30
AU1947276A (en) 1978-05-18

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PL Patent ceased