GB1523081A - 3,4-dihydro - quinazoline derivatives and process for their preparation - Google Patents

3,4-dihydro - quinazoline derivatives and process for their preparation

Info

Publication number
GB1523081A
GB1523081A GB50164/76A GB5016476A GB1523081A GB 1523081 A GB1523081 A GB 1523081A GB 50164/76 A GB50164/76 A GB 50164/76A GB 5016476 A GB5016476 A GB 5016476A GB 1523081 A GB1523081 A GB 1523081A
Authority
GB
United Kingdom
Prior art keywords
dihydro
preparation
quinazoline derivatives
quinazoline
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB50164/76A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlo Erba SpA filed Critical Carlo Erba SpA
Publication of GB1523081A publication Critical patent/GB1523081A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/93—Sulfur atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB50164/76A 1975-12-05 1976-12-01 3,4-dihydro - quinazoline derivatives and process for their preparation Expired GB1523081A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT29998/75A IT1050750B (it) 1975-12-05 1975-12-05 Derivati della 3.4 di idro chinazolina

Publications (1)

Publication Number Publication Date
GB1523081A true GB1523081A (en) 1978-08-31

Family

ID=11228830

Family Applications (1)

Application Number Title Priority Date Filing Date
GB50164/76A Expired GB1523081A (en) 1975-12-05 1976-12-01 3,4-dihydro - quinazoline derivatives and process for their preparation

Country Status (22)

Country Link
US (1) US4251531A (no)
JP (1) JPS5271485A (no)
AT (1) AT355029B (no)
AU (1) AU505660B2 (no)
BE (1) BE848696A (no)
CA (1) CA1084051A (no)
CH (2) CH626073A5 (no)
CS (1) CS194786B2 (no)
DE (1) DE2654215A1 (no)
DK (1) DK147855C (no)
FI (1) FI64359C (no)
FR (1) FR2333511A1 (no)
GB (1) GB1523081A (no)
HU (1) HU177817B (no)
IL (1) IL50849A (no)
IT (1) IT1050750B (no)
NL (1) NL7613450A (no)
NO (1) NO146095C (no)
NZ (1) NZ182778A (no)
SE (1) SE7613588L (no)
SU (1) SU786894A3 (no)
ZA (1) ZA766745B (no)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0371731A2 (en) * 1988-11-30 1990-06-06 Smith Kline & French Laboratories Limited Quinazolinone derivatives

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL69274A (en) * 1982-08-05 1986-08-31 Erba Farmitalia (substituted amino)derivatives of 3-benzylidene-pyrrolo(2,1-b)quinazolin-9-ones and 6-benzylidene-pyrido(2,1-b)quinazolin-11-ones,their preparation and pharmaceutical compositions containing them
JPS5925224U (ja) * 1982-08-10 1984-02-16 株式会社根来 かばん
US4666913A (en) * 1985-11-22 1987-05-19 William H. Rorer, Inc. Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses
US5430148A (en) * 1992-03-31 1995-07-04 Agouron Pharmaceuticals, Inc. Antiproliferative quinazolines
WO1999061406A2 (en) * 1998-05-22 1999-12-02 Abbott Laboratories Antiangiogenic drug to treat cancer, arthritis and retinopathy
US6632961B1 (en) 1998-05-22 2003-10-14 Abbott Laboratories Antiangiogenic drug to treat cancer, arthritis and retinopathy
CO5170498A1 (es) * 1999-05-28 2002-06-27 Abbott Lab Biaril sulfonamidas son utiles como inhibidores de proliferacion celular
US7893071B2 (en) * 2001-04-23 2011-02-22 University Of Virginia Patent Foundation Synthesis and evaluation of novel phthalimide mimics as anti-angiogenic
DE602004025803D1 (de) * 2003-06-06 2010-04-15 Arexis Ab Verwendung von kondensierten heterozyklischen verbindungen als scce-hemmern zur behandlung von hautzuständen
CN100518740C (zh) * 2003-06-06 2009-07-29 阿里克斯股份公司 杂环化合物作为scce抑制剂的制药用途
EP2050739B1 (en) * 2006-08-08 2016-07-06 ASKA Pharmaceutical Co., Ltd. Quinazoline derivative
DK2118074T3 (en) 2007-02-01 2014-03-10 Resverlogix Corp Compounds for the prevention and treatment of cardiovascular diseases
NZ755378A (en) 2009-03-18 2022-07-29 Resverlogix Corp Novel quinazolinones and related compounds for use as anti-inflammatory agents
US9757368B2 (en) 2009-04-22 2017-09-12 Resverlogix Corp. Anti-inflammatory agents
CA2977308A1 (en) 2015-03-13 2016-09-22 Resverlogix Corp. Compositions and therapeutic methods for the treatment of complement-associated diseases
GB201510254D0 (en) * 2015-06-12 2015-07-29 Syngenta Participations Ag Improvements in or relating to organic compounds
CA3105174A1 (en) * 2018-06-27 2020-01-02 Reborna Biosciences, Inc. Prophylactic or therapeutic agent for spinal muscular atrophy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3696102A (en) * 1970-03-09 1972-10-03 Pfizer & Co C Process for the synthesis of substituted quinazolin-4-ones

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0371731A2 (en) * 1988-11-30 1990-06-06 Smith Kline & French Laboratories Limited Quinazolinone derivatives
EP0371731A3 (en) * 1988-11-30 1991-01-02 Smith Kline & French Laboratories Limited Quinazolinone derivatives
US5147875A (en) * 1988-11-30 1992-09-15 Sanshin Kogyo Kabishiki Kaisha 2-(substituted phenyl)-4-oxo-quinazolines
AU630638B2 (en) * 1988-11-30 1992-11-05 Smith Kline & French Laboratories Limited Quinazolinonederivatives which are bronchodilators and vasodilators

Also Published As

Publication number Publication date
IL50849A (en) 1980-11-30
SU786894A3 (ru) 1980-12-07
BE848696A (fr) 1977-03-16
AT355029B (de) 1980-02-11
CS194786B2 (en) 1979-12-31
FR2333511A1 (fr) 1977-07-01
DE2654215A1 (de) 1977-06-16
NL7613450A (nl) 1977-06-07
DK147855B (da) 1984-12-24
ATA894376A (de) 1979-07-15
US4251531A (en) 1981-02-17
CH626075A5 (no) 1981-10-30
JPS5543464B2 (no) 1980-11-06
AU505660B2 (en) 1979-11-29
NZ182778A (en) 1978-07-28
DK147855C (da) 1985-06-10
SE7613588L (sv) 1977-06-06
NO764135L (no) 1977-06-07
ZA766745B (en) 1977-10-26
HU177817B (en) 1981-12-28
IT1050750B (it) 1981-03-20
FI64359C (fi) 1983-11-10
NO146095C (no) 1982-08-11
FI763391A (no) 1977-06-06
CA1084051A (en) 1980-08-19
IL50849A0 (en) 1977-01-31
DK546776A (da) 1977-06-06
FI64359B (fi) 1983-07-29
JPS5271485A (en) 1977-06-14
NO146095B (no) 1982-04-19
FR2333511B1 (no) 1979-03-02
CH626073A5 (no) 1981-10-30
AU1947276A (en) 1978-05-18

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee