CH623321A5 - Process for the preparation of heterocyclic aminoalcohol derivatives - Google Patents
Process for the preparation of heterocyclic aminoalcohol derivatives Download PDFInfo
- Publication number
- CH623321A5 CH623321A5 CH1454276A CH1454276A CH623321A5 CH 623321 A5 CH623321 A5 CH 623321A5 CH 1454276 A CH1454276 A CH 1454276A CH 1454276 A CH1454276 A CH 1454276A CH 623321 A5 CH623321 A5 CH 623321A5
- Authority
- CH
- Switzerland
- Prior art keywords
- radical
- formula
- chs
- solvent
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
- C07D327/06—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/08—Six-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7535217A FR2332010A1 (fr) | 1975-11-18 | 1975-11-18 | Amino-alcool heterocyclique, son sel et son procede de preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
CH623321A5 true CH623321A5 (en) | 1981-05-29 |
Family
ID=9162563
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH1454276A CH623321A5 (en) | 1975-11-18 | 1976-11-18 | Process for the preparation of heterocyclic aminoalcohol derivatives |
CH167280A CH622770A5 (en) | 1975-11-18 | 1980-03-03 | Process for the preparation of heterocyclic aminoalcohol derivatives |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH167280A CH622770A5 (en) | 1975-11-18 | 1980-03-03 | Process for the preparation of heterocyclic aminoalcohol derivatives |
Country Status (21)
Country | Link |
---|---|
JP (2) | JPS5297952A (de) |
AT (1) | AT355566B (de) |
AU (1) | AU510315B2 (de) |
BE (1) | BE848496A (de) |
CA (1) | CA1094088A (de) |
CH (2) | CH623321A5 (de) |
DE (1) | DE2651572C2 (de) |
DK (1) | DK151330C (de) |
ES (1) | ES453389A1 (de) |
FI (1) | FI763265A (de) |
FR (1) | FR2332010A1 (de) |
GB (1) | GB1565080A (de) |
GR (1) | GR62012B (de) |
IE (1) | IE44265B1 (de) |
IL (1) | IL50932A (de) |
MX (1) | MX4881E (de) |
NL (1) | NL180936C (de) |
NZ (1) | NZ182665A (de) |
PT (1) | PT65853B (de) |
SE (1) | SE434744B (de) |
ZA (1) | ZA766907B (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2512817A1 (fr) * | 1981-09-17 | 1983-03-18 | Roussel Uclaf | Nouveaux derives de l'aminomethyl 1h-indole-4-methanol et leurs sels, leur procede de preparation, leur application a titre de medicaments, les compositions les renfermant et leurs intermediaires de preparation |
US4622399A (en) * | 1983-06-30 | 1986-11-11 | American Home Products Corporation | Bicyclo-heterocyclic nitrogen substituted aminoethanol derivatives |
US4562200A (en) * | 1983-06-30 | 1985-12-31 | American Home Products Corporation | 5(Indolyl) and 5(2,3-dihydroindolyl) substituted aminoethanols and their use as anti-hypertensives |
US4521606A (en) * | 1983-06-30 | 1985-06-04 | American Home Products Corp. | 5-Indolyl substituted aminoethanols |
EP0567090B1 (de) | 1992-04-24 | 2000-07-26 | Takeda Chemical Industries, Ltd. | Benzoxazepin-Derivate als Cholinesterase-Inhibitoren |
US5561142A (en) * | 1994-04-26 | 1996-10-01 | Merck & Co., Inc. | Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity |
US5705515A (en) * | 1994-04-26 | 1998-01-06 | Merck & Co., Inc. | Substituted sulfonamides as selective β-3 agonists for the treatment of diabetes and obesity |
US5541197A (en) * | 1994-04-26 | 1996-07-30 | Merck & Co., Inc. | Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity |
US5674891A (en) * | 1994-07-27 | 1997-10-07 | The Procter & Gamble Company | Dihydrobenzothiophene compounds useful as anti-inflammatory agents |
US5684002A (en) * | 1994-09-07 | 1997-11-04 | The Procter & Gamble Company | Dihydorbenzofuran and related compounds useful as anti-inflammatory agents |
WO1997025311A1 (fr) | 1996-01-10 | 1997-07-17 | Asahi Kasei Kogyo Kabushiki Kaisha | Nouveaux composes tricycliques et compositions medicamenteuses contenant ces composes |
US5684031A (en) * | 1996-02-01 | 1997-11-04 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
US5672620A (en) * | 1996-02-01 | 1997-09-30 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
WO1998033793A1 (fr) * | 1997-01-30 | 1998-08-06 | Sanofi-Synthelabo | DERIVES DE α-AZACYCLOMETHYL BENZOTHIOPHENE ET DE α-AZACYCLOMETHYL BENZOFURANE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE |
FR2758820B1 (fr) * | 1997-01-30 | 1999-02-26 | Synthelabo | Derives de alpha-azacyclomethyl-benzofurane, leur preparation et leur application en therapeutique |
WO1999001431A1 (fr) * | 1997-07-03 | 1999-01-14 | Asahi Kasei Kogyo Kabushiki Kaisha | Nouveaux composes tricycliques presentant des noyaux satures et compositions medicinales les contenant |
DK1277736T3 (da) | 2000-04-28 | 2007-10-01 | Asahi Kasei Pharma Corp | Hidtil ukendte bicykliske forbindelser |
DK1447400T3 (da) | 2001-10-25 | 2008-12-08 | Asahi Kasei Pharma Corp | Bicyklisk forbindelse |
CN102171192A (zh) | 2008-10-09 | 2011-08-31 | 旭化成制药株式会社 | 吲唑化合物 |
CA2737349A1 (en) | 2008-10-09 | 2010-04-09 | Asahi Kasei Pharma Corporation | Indazole derivatives |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1013224A (en) * | 1962-06-21 | 1965-12-15 | Ici Ltd | Heterocyclic aminoethanols |
US3255249A (en) * | 1963-04-26 | 1966-06-07 | Ici Ltd | 2-branched lower alkyl-amino-1-(indan-, hydrogenated indan- and hydrogenated naphth-2-yl) lower alkanols |
CH442302A (de) * | 1964-04-17 | 1967-08-31 | Sandoz Ag | Verfahren zur Herstellung eines neuen Indolderivates |
FR2138488A1 (en) * | 1971-05-27 | 1973-01-05 | Lipha | 1-(5-indanyl)-omega-aminoalkanes - with tranquillizing activity |
-
1975
- 1975-11-18 FR FR7535217A patent/FR2332010A1/fr active Granted
-
1976
- 1976-11-11 SE SE7612554A patent/SE434744B/xx not_active IP Right Cessation
- 1976-11-12 DE DE2651572A patent/DE2651572C2/de not_active Expired
- 1976-11-15 FI FI763265A patent/FI763265A/fi not_active Application Discontinuation
- 1976-11-17 IL IL50932A patent/IL50932A/xx unknown
- 1976-11-17 DK DK517076A patent/DK151330C/da not_active IP Right Cessation
- 1976-11-17 PT PT65853A patent/PT65853B/pt unknown
- 1976-11-17 MX MX765135U patent/MX4881E/es unknown
- 1976-11-17 AT AT854376A patent/AT355566B/de not_active IP Right Cessation
- 1976-11-17 ES ES453389A patent/ES453389A1/es not_active Expired
- 1976-11-17 NL NLAANVRAGE7612794,A patent/NL180936C/xx not_active IP Right Cessation
- 1976-11-18 IE IE2541/76A patent/IE44265B1/en unknown
- 1976-11-18 CH CH1454276A patent/CH623321A5/fr not_active IP Right Cessation
- 1976-11-18 CA CA266,041A patent/CA1094088A/en not_active Expired
- 1976-11-18 GR GR52209A patent/GR62012B/el unknown
- 1976-11-18 AU AU19779/76A patent/AU510315B2/en not_active Expired
- 1976-11-18 GB GB48127/76A patent/GB1565080A/en not_active Expired
- 1976-11-18 BE BE172486A patent/BE848496A/xx not_active IP Right Cessation
- 1976-11-18 JP JP13785976A patent/JPS5297952A/ja active Granted
- 1976-11-18 ZA ZA766907A patent/ZA766907B/xx unknown
- 1976-11-18 NZ NZ182665A patent/NZ182665A/xx unknown
-
1980
- 1980-03-03 CH CH167280A patent/CH622770A5/fr not_active IP Right Cessation
-
1982
- 1982-01-12 JP JP57002388A patent/JPS6017778B2/ja not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS57145843A (en) | 1982-09-09 |
ES453389A1 (es) | 1977-11-16 |
IL50932A0 (en) | 1977-01-31 |
IE44265L (en) | 1977-05-18 |
PT65853A (fr) | 1976-12-01 |
ZA766907B (en) | 1977-10-26 |
MX4881E (es) | 1982-11-30 |
AU1977976A (en) | 1978-05-25 |
GR62012B (en) | 1979-02-15 |
SE434744B (sv) | 1984-08-13 |
AT355566B (de) | 1980-03-10 |
FI763265A (de) | 1977-05-19 |
DE2651572A1 (de) | 1977-06-08 |
JPS63435B2 (de) | 1988-01-07 |
JPS5297952A (en) | 1977-08-17 |
JPS6017778B2 (ja) | 1985-05-07 |
NL180936B (nl) | 1986-12-16 |
BE848496A (fr) | 1977-05-18 |
DE2651572C2 (de) | 1982-05-19 |
FR2332010B1 (de) | 1979-06-29 |
SE7612554L (sv) | 1977-05-19 |
DK517076A (da) | 1977-05-19 |
NL180936C (nl) | 1987-05-18 |
ATA854376A (de) | 1979-08-15 |
GB1565080A (en) | 1980-04-16 |
NZ182665A (en) | 1978-11-13 |
AU510315B2 (en) | 1980-06-19 |
PT65853B (fr) | 1978-05-15 |
CH622770A5 (en) | 1981-04-30 |
IE44265B1 (en) | 1981-09-23 |
DK151330B (da) | 1987-11-23 |
CA1094088A (en) | 1981-01-20 |
FR2332010A1 (fr) | 1977-06-17 |
IL50932A (en) | 1984-01-31 |
NL7612794A (nl) | 1977-05-23 |
DK151330C (da) | 1988-04-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUE | Assignment |
Owner name: CONTINENTAL PHARMA, INC. |
|
PL | Patent ceased |