CH609064A5 - Process for the preparation of dihydroxy-1,3,5(10)-8alpha-oestratrienes or their ethers or esters - Google Patents

Process for the preparation of dihydroxy-1,3,5(10)-8alpha-oestratrienes or their ethers or esters

Info

Publication number
CH609064A5
CH609064A5 CH964674A CH964674A CH609064A5 CH 609064 A5 CH609064 A5 CH 609064A5 CH 964674 A CH964674 A CH 964674A CH 964674 A CH964674 A CH 964674A CH 609064 A5 CH609064 A5 CH 609064A5
Authority
CH
Switzerland
Prior art keywords
oestratrienes
8alpha
dihydroxy
ethers
esters
Prior art date
Application number
CH964674A
Other languages
English (en)
Inventor
Klaus Dr Prezewowsky
Henry Dr Laurent
Helmut Dr Hofmeister
Rudolf Prof Dr Wiechert
Friedmund Dr Neumann
Yukishige Dr Nishino
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2336431A external-priority patent/DE2336431C2/de
Priority claimed from DE19742426777 external-priority patent/DE2426777A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of CH609064A5 publication Critical patent/CH609064A5/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0074—Esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J15/00—Stereochemically pure steroids containing carbon, hydrogen, halogen or oxygen having a partially or totally inverted skeleton, e.g. retrosteroids, L-isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
CH964674A 1973-07-13 1974-07-12 Process for the preparation of dihydroxy-1,3,5(10)-8alpha-oestratrienes or their ethers or esters CH609064A5 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2336431A DE2336431C2 (de) 1973-07-13 1973-07-13 1.3-oxygenierte 8 alpha-Östratriene, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE19742426777 DE2426777A1 (de) 1974-05-31 1974-05-31 1.3-oxygenierte 8 alpha-oestratriene

Publications (1)

Publication Number Publication Date
CH609064A5 true CH609064A5 (en) 1979-02-15

Family

ID=25765510

Family Applications (2)

Application Number Title Priority Date Filing Date
CH964674A CH609064A5 (en) 1973-07-13 1974-07-12 Process for the preparation of dihydroxy-1,3,5(10)-8alpha-oestratrienes or their ethers or esters
CH1035978A CH614217A5 (en) 1973-07-13 1974-07-12 Process for the preparation of 1,3,5(10)-8alpha-oestratrienes

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH1035978A CH614217A5 (en) 1973-07-13 1974-07-12 Process for the preparation of 1,3,5(10)-8alpha-oestratrienes

Country Status (18)

Country Link
JP (1) JPS5821639B2 (enrdf_load_stackoverflow)
AT (1) ATA575574A (enrdf_load_stackoverflow)
AU (1) AU477010B2 (enrdf_load_stackoverflow)
CA (1) CA1030951A (enrdf_load_stackoverflow)
CH (2) CH609064A5 (enrdf_load_stackoverflow)
CS (2) CS182300B2 (enrdf_load_stackoverflow)
DD (1) DD114066A5 (enrdf_load_stackoverflow)
DK (1) DK133051C (enrdf_load_stackoverflow)
ES (1) ES428226A1 (enrdf_load_stackoverflow)
FI (1) FI54131C (enrdf_load_stackoverflow)
FR (1) FR2236505B1 (enrdf_load_stackoverflow)
GB (1) GB1479934A (enrdf_load_stackoverflow)
HU (1) HU169791B (enrdf_load_stackoverflow)
IE (1) IE39872B1 (enrdf_load_stackoverflow)
IL (1) IL45259A (enrdf_load_stackoverflow)
NO (1) NO742546L (enrdf_load_stackoverflow)
SE (1) SE7409151L (enrdf_load_stackoverflow)
SU (1) SU626705A3 (enrdf_load_stackoverflow)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2551214C2 (de) * 1975-11-12 1984-07-12 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur Herstellung von 1,3-oxygenierten 8α-Östratrienen
JPS5862734U (ja) * 1981-10-22 1983-04-27 日工株式会社 型枠支持サボ−ト
JPS59146759A (ja) * 1984-01-06 1984-08-22 株式会社日立製作所 自動ねじ込み装置
JPS60155376A (ja) * 1984-01-24 1985-08-15 松下電器産業株式会社 ナツト浮き検出装置
DE3710728A1 (de) * 1987-03-31 1988-10-13 Schering Ag Verfahren zur herstellung von 17(alpha)-ethinyl-17ss-hydroxy-18-methyl-4,15-estradien-3-on und die neuen zwischenprodukte fuer dieses verfahren
US6011024A (en) 1991-08-28 2000-01-04 Imperial College Of Science Technology & Medicine Steroid sulphatase inhibitors
US6903084B2 (en) 1991-08-28 2005-06-07 Sterix Limited Steroid sulphatase inhibitors
US6476011B1 (en) 1991-08-28 2002-11-05 Sterix Limited Methods for introducing an estrogenic compound
US7335650B2 (en) 2000-01-14 2008-02-26 Sterix Limited Composition
GB0020498D0 (en) 2000-08-18 2000-10-11 Sterix Ltd Compound
RU2679625C1 (ru) * 2018-11-08 2019-02-12 Ильясов Шамиль Сионович ПРИМЕНЕНИЕ 3-О-СУЛЬФАМОИЛОКСИ-6-ОКСА-7β-МЕТИЛ-D-ГОМО-8α-ЭСТРА-1,3,5(10)-ТРИЕН-17а-ОНА ДЛЯ ЛЕЧЕНИЯ РАКА МОЛОЧНОЙ ЖЕЛЕЗЫ, ВКЛЮЧАЯ ТРИЖДЫ-НЕГАТИВНУЮ ФОРМУ, И СПОСОБ ЕГО ПОЛУЧЕНИЯ

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3436411A (en) * 1967-12-28 1969-04-01 American Home Prod Process for cleaving an a-ring ether group in 13-alkylgona (and 8-isogona)-1,3,5(10)-trienes and delta-7-,delta-8(9)-,and delta-8(9),14(15)-dehydro derivatives thereof

Also Published As

Publication number Publication date
HU169791B (en) 1977-01-28
ES428226A1 (es) 1976-07-16
DK133051B (da) 1976-03-15
FI54131B (fi) 1978-06-30
ATA575574A (de) 1978-05-15
IE39872B1 (en) 1979-01-17
JPS5821639B2 (ja) 1983-05-02
FI213974A7 (enrdf_load_stackoverflow) 1975-01-14
DD114066A5 (enrdf_load_stackoverflow) 1975-07-12
SE7409151L (sv) 1975-01-14
CH614217A5 (en) 1979-11-15
DK133051C (da) 1976-08-16
GB1479934A (en) 1977-07-13
CS182260B2 (en) 1978-04-28
IL45259A0 (en) 1974-10-22
SU626705A3 (ru) 1978-09-30
DK368074A (enrdf_load_stackoverflow) 1975-03-17
AU477010B2 (en) 1976-10-14
IE39872L (en) 1975-01-13
FR2236505B1 (enrdf_load_stackoverflow) 1977-07-08
IL45259A (en) 1977-10-31
CA1030951A (en) 1978-05-09
JPS5032160A (enrdf_load_stackoverflow) 1975-03-28
NO742546L (enrdf_load_stackoverflow) 1975-02-10
FR2236505A1 (enrdf_load_stackoverflow) 1975-02-07
FI54131C (fi) 1978-10-10
CS182300B2 (en) 1978-04-28
AU7112374A (en) 1976-01-15

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Legal Events

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PL Patent ceased
PL Patent ceased