CA1030951A - 1,3-OXYGENATED 8.alpha.-OESTRATRIENES - Google Patents

1,3-OXYGENATED 8.alpha.-OESTRATRIENES

Info

Publication number
CA1030951A
CA1030951A CA204,667A CA204667A CA1030951A CA 1030951 A CA1030951 A CA 1030951A CA 204667 A CA204667 A CA 204667A CA 1030951 A CA1030951 A CA 1030951A
Authority
CA
Canada
Prior art keywords
oestratrienes
oxygenated
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA204,667A
Other languages
French (fr)
Inventor
Klaus Prezewowsky
Henry Laurent
Friedmund Neumann
Rudolf Wiechert
Helmut Hofmeister
Yukishige Nishino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2336431A external-priority patent/DE2336431C2/en
Priority claimed from DE19742426777 external-priority patent/DE2426777A1/en
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of CA1030951A publication Critical patent/CA1030951A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0066Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0074Esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0059Estrane derivatives substituted in position 17 by a keto group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J15/00Stereochemically pure steroids containing carbon, hydrogen, halogen or oxygen having a partially or totally inverted skeleton, e.g. retrosteroids, L-isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
CA204,667A 1973-07-13 1974-07-12 1,3-OXYGENATED 8.alpha.-OESTRATRIENES Expired CA1030951A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2336431A DE2336431C2 (en) 1973-07-13 1973-07-13 1.3-oxygenated 8-alpha-estratrienes, processes for their production and pharmaceuticals containing them
DE19742426777 DE2426777A1 (en) 1974-05-31 1974-05-31 1,3-Oxygenated-8-alpha-oestratrienes for post-menopausal disorders - with vaginotropic, but low uterotrophic activity

Publications (1)

Publication Number Publication Date
CA1030951A true CA1030951A (en) 1978-05-09

Family

ID=25765510

Family Applications (1)

Application Number Title Priority Date Filing Date
CA204,667A Expired CA1030951A (en) 1973-07-13 1974-07-12 1,3-OXYGENATED 8.alpha.-OESTRATRIENES

Country Status (18)

Country Link
JP (1) JPS5821639B2 (en)
AT (1) ATA575574A (en)
AU (1) AU477010B2 (en)
CA (1) CA1030951A (en)
CH (2) CH614217A5 (en)
CS (2) CS182260B2 (en)
DD (1) DD114066A5 (en)
DK (1) DK133051C (en)
ES (1) ES428226A1 (en)
FI (1) FI54131C (en)
FR (1) FR2236505B1 (en)
GB (1) GB1479934A (en)
HU (1) HU169791B (en)
IE (1) IE39872B1 (en)
IL (1) IL45259A (en)
NO (1) NO742546L (en)
SE (1) SE7409151L (en)
SU (1) SU626705A3 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2551214C2 (en) * 1975-11-12 1984-07-12 Schering AG, 1000 Berlin und 4709 Bergkamen Process for the preparation of 1,3-oxygenated 8α-estatrienes
JPS5862734U (en) * 1981-10-22 1983-04-27 日工株式会社 formwork support sabot
JPS59146759A (en) * 1984-01-06 1984-08-22 株式会社日立製作所 Automatic screwing device
JPS60155376A (en) * 1984-01-24 1985-08-15 松下電器産業株式会社 Nut float detection apparatus
DE3710728A1 (en) * 1987-03-31 1988-10-13 Schering Ag METHOD FOR PRODUCING 17 (ALPHA) -ETHINYL-17SS-HYDROXY-18-METHYL-4.15-ESTRADIEN-3-ON AND THE NEW INTERMEDIATE PRODUCTS FOR THIS METHOD
US6011024A (en) 1991-08-28 2000-01-04 Imperial College Of Science Technology & Medicine Steroid sulphatase inhibitors
US6476011B1 (en) 1991-08-28 2002-11-05 Sterix Limited Methods for introducing an estrogenic compound
US6903084B2 (en) 1991-08-29 2005-06-07 Sterix Limited Steroid sulphatase inhibitors
US7335650B2 (en) 2000-01-14 2008-02-26 Sterix Limited Composition
GB0020498D0 (en) 2000-08-18 2000-10-11 Sterix Ltd Compound
RU2679625C1 (en) * 2018-11-08 2019-02-12 Ильясов Шамиль Сионович 3-o-sulfamoiloxy-6-oxa-7β-methyl-d-homo-8α-estra-1,3,5(10)-trien-17α-one application for the breast cancer treatment, including the triple negative form, and its production method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3436411A (en) * 1967-12-28 1969-04-01 American Home Prod Process for cleaving an a-ring ether group in 13-alkylgona (and 8-isogona)-1,3,5(10)-trienes and delta-7-,delta-8(9)-,and delta-8(9),14(15)-dehydro derivatives thereof

Also Published As

Publication number Publication date
FR2236505A1 (en) 1975-02-07
ES428226A1 (en) 1976-07-16
JPS5032160A (en) 1975-03-28
FI54131C (en) 1978-10-10
IL45259A (en) 1977-10-31
JPS5821639B2 (en) 1983-05-02
ATA575574A (en) 1978-05-15
IE39872L (en) 1975-01-13
FI54131B (en) 1978-06-30
GB1479934A (en) 1977-07-13
DK133051B (en) 1976-03-15
IE39872B1 (en) 1979-01-17
NO742546L (en) 1975-02-10
CH614217A5 (en) 1979-11-15
FI213974A (en) 1975-01-14
HU169791B (en) 1977-01-28
SE7409151L (en) 1975-01-14
CS182300B2 (en) 1978-04-28
CH609064A5 (en) 1979-02-15
DD114066A5 (en) 1975-07-12
DK368074A (en) 1975-03-17
FR2236505B1 (en) 1977-07-08
AU477010B2 (en) 1976-10-14
AU7112374A (en) 1976-01-15
IL45259A0 (en) 1974-10-22
CS182260B2 (en) 1978-04-28
DK133051C (en) 1976-08-16
SU626705A3 (en) 1978-09-30

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