FI54131B - Foerfarande foer framstaellning av 1,3-hydroxiderivat av 8alfa-oestratriener vilka laempar sig foer behandling av oestrogenbrist - Google Patents

Foerfarande foer framstaellning av 1,3-hydroxiderivat av 8alfa-oestratriener vilka laempar sig foer behandling av oestrogenbrist

Info

Publication number
FI54131B
FI54131B FI2139/74A FI213974A FI54131B FI 54131 B FI54131 B FI 54131B FI 2139/74 A FI2139/74 A FI 2139/74A FI 213974 A FI213974 A FI 213974A FI 54131 B FI54131 B FI 54131B
Authority
FI
Finland
Prior art keywords
foer
oestrogenbrist
oestratriener
hydroxiderivat
8alfa
Prior art date
Application number
FI2139/74A
Other languages
English (en)
Other versions
FI54131C (fi
FI213974A (fi
Inventor
Klaus Prezewowsky
Henry Laurent
Helmut Hofmeister
Rudolf Wiechert
Friedmund Neumann
Yukishige Nishino
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2336431A external-priority patent/DE2336431C2/de
Priority claimed from DE19742426777 external-priority patent/DE2426777A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of FI213974A publication Critical patent/FI213974A/fi
Application granted granted Critical
Publication of FI54131B publication Critical patent/FI54131B/fi
Publication of FI54131C publication Critical patent/FI54131C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0066Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0074Esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0059Estrane derivatives substituted in position 17 by a keto group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J15/00Stereochemically pure steroids containing carbon, hydrogen, halogen or oxygen having a partially or totally inverted skeleton, e.g. retrosteroids, L-isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
FI2139/74A 1973-07-13 1974-07-12 Foerfarande foer framstaellning av 1,3-hydroxiderivat av 8alfa-oestratriener vilka laempar sig foer behandling av oestrogenbrist FI54131C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2336431A DE2336431C2 (de) 1973-07-13 1973-07-13 1.3-oxygenierte 8 alpha-Östratriene, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE19742426777 DE2426777A1 (de) 1974-05-31 1974-05-31 1.3-oxygenierte 8 alpha-oestratriene

Publications (3)

Publication Number Publication Date
FI213974A FI213974A (fi) 1975-01-14
FI54131B true FI54131B (fi) 1978-06-30
FI54131C FI54131C (fi) 1978-10-10

Family

ID=25765510

Family Applications (1)

Application Number Title Priority Date Filing Date
FI2139/74A FI54131C (fi) 1973-07-13 1974-07-12 Foerfarande foer framstaellning av 1,3-hydroxiderivat av 8alfa-oestratriener vilka laempar sig foer behandling av oestrogenbrist

Country Status (18)

Country Link
JP (1) JPS5821639B2 (fi)
AT (1) ATA575574A (fi)
AU (1) AU477010B2 (fi)
CA (1) CA1030951A (fi)
CH (2) CH609064A5 (fi)
CS (2) CS182300B2 (fi)
DD (1) DD114066A5 (fi)
DK (1) DK133051C (fi)
ES (1) ES428226A1 (fi)
FI (1) FI54131C (fi)
FR (1) FR2236505B1 (fi)
GB (1) GB1479934A (fi)
HU (1) HU169791B (fi)
IE (1) IE39872B1 (fi)
IL (1) IL45259A (fi)
NO (1) NO742546L (fi)
SE (1) SE7409151L (fi)
SU (1) SU626705A3 (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2551214C2 (de) * 1975-11-12 1984-07-12 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur Herstellung von 1,3-oxygenierten 8α-Östratrienen
JPS5862734U (ja) * 1981-10-22 1983-04-27 日工株式会社 型枠支持サボ−ト
JPS59146759A (ja) * 1984-01-06 1984-08-22 株式会社日立製作所 自動ねじ込み装置
JPS60155376A (ja) * 1984-01-24 1985-08-15 松下電器産業株式会社 ナツト浮き検出装置
DE3710728A1 (de) * 1987-03-31 1988-10-13 Schering Ag Verfahren zur herstellung von 17(alpha)-ethinyl-17ss-hydroxy-18-methyl-4,15-estradien-3-on und die neuen zwischenprodukte fuer dieses verfahren
US6476011B1 (en) 1991-08-28 2002-11-05 Sterix Limited Methods for introducing an estrogenic compound
US6011024A (en) 1991-08-28 2000-01-04 Imperial College Of Science Technology & Medicine Steroid sulphatase inhibitors
US6903084B2 (en) 1991-08-29 2005-06-07 Sterix Limited Steroid sulphatase inhibitors
US7335650B2 (en) 2000-01-14 2008-02-26 Sterix Limited Composition
GB0020498D0 (en) 2000-08-18 2000-10-11 Sterix Ltd Compound
RU2679625C1 (ru) * 2018-11-08 2019-02-12 Ильясов Шамиль Сионович ПРИМЕНЕНИЕ 3-О-СУЛЬФАМОИЛОКСИ-6-ОКСА-7β-МЕТИЛ-D-ГОМО-8α-ЭСТРА-1,3,5(10)-ТРИЕН-17а-ОНА ДЛЯ ЛЕЧЕНИЯ РАКА МОЛОЧНОЙ ЖЕЛЕЗЫ, ВКЛЮЧАЯ ТРИЖДЫ-НЕГАТИВНУЮ ФОРМУ, И СПОСОБ ЕГО ПОЛУЧЕНИЯ

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3436411A (en) * 1967-12-28 1969-04-01 American Home Prod Process for cleaving an a-ring ether group in 13-alkylgona (and 8-isogona)-1,3,5(10)-trienes and delta-7-,delta-8(9)-,and delta-8(9),14(15)-dehydro derivatives thereof

Also Published As

Publication number Publication date
HU169791B (en) 1977-01-28
AU7112374A (en) 1976-01-15
DK368074A (fi) 1975-03-17
FR2236505B1 (fi) 1977-07-08
ATA575574A (de) 1978-05-15
CA1030951A (en) 1978-05-09
CH609064A5 (en) 1979-02-15
DK133051C (da) 1976-08-16
NO742546L (fi) 1975-02-10
CS182260B2 (en) 1978-04-28
DK133051B (da) 1976-03-15
AU477010B2 (en) 1976-10-14
SE7409151L (sv) 1975-01-14
GB1479934A (en) 1977-07-13
JPS5821639B2 (ja) 1983-05-02
FI54131C (fi) 1978-10-10
JPS5032160A (fi) 1975-03-28
IE39872L (en) 1975-01-13
CH614217A5 (en) 1979-11-15
SU626705A3 (ru) 1978-09-30
IL45259A0 (en) 1974-10-22
DD114066A5 (fi) 1975-07-12
IL45259A (en) 1977-10-31
FR2236505A1 (fi) 1975-02-07
CS182300B2 (en) 1978-04-28
IE39872B1 (en) 1979-01-17
ES428226A1 (es) 1976-07-16
FI213974A (fi) 1975-01-14

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