CH528500A - Verfahren zur Herstellung von 25-Hydroxycholecalciferol-Derivaten - Google Patents

Verfahren zur Herstellung von 25-Hydroxycholecalciferol-Derivaten

Info

Publication number
CH528500A
CH528500A CH398070A CH398070A CH528500A CH 528500 A CH528500 A CH 528500A CH 398070 A CH398070 A CH 398070A CH 398070 A CH398070 A CH 398070A CH 528500 A CH528500 A CH 528500A
Authority
CH
Switzerland
Prior art keywords
hydroxycholecalciferol
derivatives
preparation
hydroxycholecalciferol derivatives
Prior art date
Application number
CH398070A
Other languages
English (en)
Inventor
Claude Babcock John
Campbell J Allan
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of CH528500A publication Critical patent/CH528500A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
CH398070A 1969-03-17 1970-03-17 Verfahren zur Herstellung von 25-Hydroxycholecalciferol-Derivaten CH528500A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00807929A US3833622A (en) 1969-03-17 1969-03-17 Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds

Publications (1)

Publication Number Publication Date
CH528500A true CH528500A (de) 1972-09-30

Family

ID=25197461

Family Applications (1)

Application Number Title Priority Date Filing Date
CH398070A CH528500A (de) 1969-03-17 1970-03-17 Verfahren zur Herstellung von 25-Hydroxycholecalciferol-Derivaten

Country Status (10)

Country Link
US (1) US3833622A (de)
JP (1) JPS4934980B1 (de)
BE (1) BE747492A (de)
CA (1) CA968789A (de)
CH (1) CH528500A (de)
DE (1) DE2012167C2 (de)
FR (1) FR2035000B1 (de)
GB (1) GB1286761A (de)
IL (1) IL33860A (de)
NL (1) NL7003686A (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4012509A (en) * 1974-06-10 1977-03-15 The Upjohn Company Composition of matter and process
US3907843A (en) * 1974-06-14 1975-09-23 Wisconsin Alumni Res Found 1{60 -Hydroxyergocalciferol and processes for preparing same
US3906014A (en) * 1974-06-17 1975-09-16 Wisconsin Alumni Res Found 3-Deoxy-1{60 -hydroxycholecalciferol
US4001096A (en) * 1975-02-21 1977-01-04 The Upjohn Company Process for preparing 25-hydroxycholecalciferol intermediates
US3993675A (en) * 1975-02-24 1976-11-23 Hoffmann-La Roche Inc. Process for the preparation of 1α,25-dihydroxycholecalciferol
US4069321A (en) * 1975-10-14 1978-01-17 Merck & Co., Inc. Blocked cholecalciferol and dihydrotachysterol 3 derivatives
JPS603045B2 (ja) * 1976-04-19 1985-01-25 中外製薬株式会社 １α―ヒドロキシビタミンＤ類軟カプセルの製造方法
USRE30538E (en) * 1977-03-07 1981-03-03 Wisconsin Alumni Research Foundation 3-Deoxy-1α-hydroxycholecalciferol
US4217288A (en) * 1977-03-24 1980-08-12 Wisconsin Alumni Research Foundation Anti-vitamin D compounds
US4119647A (en) * 1977-04-11 1978-10-10 Hoffmann-La Roche Inc. 25-Hydroxycholecalciferol-23,24-3 H and process for the preparation thereof
JPS6039278B2 (ja) * 1977-05-23 1985-09-05 中外製薬株式会社 ステロイド誘導体
US4183852A (en) * 1977-07-18 1980-01-15 Kaiser Emil T Process for preparing 25-hydroxycholesterol
JPS5822479B2 (ja) * 1977-09-07 1983-05-09 帝人株式会社 １α−ヒドロキシ−２４−オキソ−ビタミンＤ↓３およびその製造法
US4188345A (en) * 1978-07-26 1980-02-12 Wisconsin Alumni Research Foundation Fluorovitamin D compounds and processes for their preparation
US4225596A (en) * 1978-10-13 1980-09-30 Wisconsin Alumni Research Foundation Method for treating calcium imbalance and improving calcium absorption in mammals
US4269777A (en) * 1979-05-21 1981-05-26 Wisconsin Alumni Research Foundation Isotopically labeled vitamin D derivatives and processes for preparing same
FR2457282A1 (fr) * 1979-05-23 1980-12-19 Roussel Uclaf Nouveau derive du 1a,25 dihydroxy cholecalciferol, son procede de preparation et son application comme medicament
IL60270A0 (en) * 1979-06-14 1980-09-16 Diamond Shamrock Corp Preparation of 25-ydroxycholesterol
US4252797A (en) * 1979-07-19 1981-02-24 Walter Rosenthal Corticosteroid calcium compositions and treatment of rheumatic diseases therewith
US4260804A (en) * 1980-02-20 1981-04-07 Wisconsin Alumni Research Foundation Processes for preparing calcitroic acid and esters thereof
CH672920A5 (de) * 1984-10-04 1990-01-15 Wisconsin Alumni Res Found
US5043170A (en) * 1989-02-14 1991-08-27 Hoffmann-La Roche Inc. Animal feed composition containing a vitamin D metabolite
KR960013798B1 (ko) * 1992-04-24 1996-10-10 재단법인 한국전자통신연구소 평면 도파로형 공간 스위치
AU666529B2 (en) * 1992-04-24 1996-02-15 Wisconsin Alumni Research Foundation Method of treating osteoporosis with 1 alpha, 24 (R)-dihydroxy-22 (E)-dehydro-vitamin D3
US5194431A (en) 1992-07-08 1993-03-16 Wisconsin Alumni Research Foundation 24-cyclopropane vitamin D derivatives
CA2184598C (en) 1994-04-15 2005-05-03 Jeffrey L. Havens Novel crystal forms of 1-[5-methanesulfonamidoindolyl-2-carbonyl]-4-[3-(1-methylethylamino)-2-pyridinyl]piperazine
US6432936B1 (en) 1999-01-20 2002-08-13 Wisconsin Alumni Research Foundation Crystalline 1α-hydroxyvitamin D2 and method of purification thereof
US7235655B2 (en) * 2002-03-22 2007-06-26 Pharmacia & Upjohn Company Processes to prepare eplerenone
DK1993559T3 (en) 2006-02-03 2016-10-03 Opko Renal Llc Treatment of vitamin D deficiency and MALFUNCTION with 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3
ES2670029T3 (es) 2006-06-21 2018-05-29 Opko Ireland Global Holdings, Ltd. Terapia usando agente de repleción de la vitamina D y agente de reemplazo de la hormona de la vitamina D
KR101495578B1 (ko) 2007-04-25 2015-02-25 사이토크로마 인코포레이티드 비타민 ｄ 부족 및 결핍의 치료 방법
EP3225243A1 (de) 2007-04-25 2017-10-04 Opko Renal, LLC Verfahren zur sicheren und effektiven behandlung und vorbeugung von sekundärem hyperparathyroidismus für chronische nierenerkrankung
DK2481400T3 (da) 2007-04-25 2014-09-29 Opko Ip Holdings Ii Inc Orale præparater med kontrolleret frigivelse omfattende en vitamin D-forbindelse og en voksagtig bærer
ES2954932T3 (es) 2008-04-02 2023-11-27 Eirgen Pharma Ltd Métodos, composiciones, usos y kits útiles para la deficiencia de vitamina D y trastornos relacionados
CN105796530A (zh) 2010-03-29 2016-07-27 赛特克罗公司 用于降低甲状旁腺水平的方法和组合物
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 ｄ 방출 제형
US10220047B2 (en) 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
IL290855B2 (en) 2016-03-28 2024-06-01 Eirgen Pharma Ltd Treatment methods using vitamin D

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2012069B1 (de) * 1968-07-01 1973-06-08 Wisconsin Alumni Res Found

Also Published As

Publication number Publication date
FR2035000B1 (de) 1974-01-11
NL7003686A (de) 1970-09-21
FR2035000A1 (de) 1970-12-18
US3833622A (en) 1974-09-03
DE2012167A1 (de) 1970-10-01
IL33860A (en) 1973-10-25
JPS4934980B1 (de) 1974-09-19
DE2012167C2 (de) 1982-09-23
IL33860A0 (en) 1970-04-20
GB1286761A (en) 1972-08-23
BE747492A (fr) 1970-09-17
CA968789A (en) 1975-06-03

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