CH512244A - Mittel zur Erhaltung der Mundhygiene - Google Patents
Mittel zur Erhaltung der MundhygieneInfo
- Publication number
- CH512244A CH512244A CH1109468A CH1109468A CH512244A CH 512244 A CH512244 A CH 512244A CH 1109468 A CH1109468 A CH 1109468A CH 1109468 A CH1109468 A CH 1109468A CH 512244 A CH512244 A CH 512244A
- Authority
- CH
- Switzerland
- Prior art keywords
- dextranase
- vehicle
- units
- teeth
- enzyme
- Prior art date
Links
- 108010001682 Dextranase Proteins 0.000 title claims abstract description 29
- 238000002360 preparation method Methods 0.000 title abstract description 7
- 230000015572 biosynthetic process Effects 0.000 claims abstract description 10
- 239000000203 mixture Substances 0.000 claims abstract description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 229940112822 chewing gum Drugs 0.000 claims abstract description 6
- 235000015218 chewing gum Nutrition 0.000 claims abstract description 6
- 239000000606 toothpaste Substances 0.000 claims abstract description 6
- 229940034610 toothpaste Drugs 0.000 claims abstract description 6
- 239000000843 powder Substances 0.000 claims abstract description 5
- 239000002674 ointment Substances 0.000 claims abstract description 4
- 230000001055 chewing effect Effects 0.000 claims abstract description 3
- 238000000576 coating method Methods 0.000 claims description 15
- 239000011248 coating agent Substances 0.000 claims description 14
- 239000002324 mouth wash Substances 0.000 claims description 7
- 229940051866 mouthwash Drugs 0.000 claims description 7
- 239000007937 lozenge Substances 0.000 claims description 2
- 239000007910 chewable tablet Substances 0.000 claims 1
- 229940068682 chewable tablet Drugs 0.000 claims 1
- 229920002307 Dextran Polymers 0.000 abstract description 20
- 241001136494 Talaromyces funiculosus Species 0.000 abstract description 6
- 201000010099 disease Diseases 0.000 abstract description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 6
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 abstract description 4
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 abstract description 2
- 208000002064 Dental Plaque Diseases 0.000 abstract description 2
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 abstract description 2
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 abstract description 2
- 229910052921 ammonium sulfate Inorganic materials 0.000 abstract description 2
- 235000011130 ammonium sulphate Nutrition 0.000 abstract description 2
- 229960001230 asparagine Drugs 0.000 abstract description 2
- 235000009582 asparagine Nutrition 0.000 abstract description 2
- 235000013305 food Nutrition 0.000 abstract description 2
- 229910052943 magnesium sulfate Inorganic materials 0.000 abstract description 2
- 235000019341 magnesium sulphate Nutrition 0.000 abstract description 2
- 239000001963 growth medium Substances 0.000 abstract 2
- 239000000001 dental powder Substances 0.000 abstract 1
- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 abstract 1
- 229910000396 dipotassium phosphate Inorganic materials 0.000 abstract 1
- 235000019797 dipotassium phosphate Nutrition 0.000 abstract 1
- 239000012467 final product Substances 0.000 abstract 1
- BAUYGSIQEAFULO-UHFFFAOYSA-L iron(2+) sulfate (anhydrous) Chemical compound [Fe+2].[O-]S([O-])(=O)=O BAUYGSIQEAFULO-UHFFFAOYSA-L 0.000 abstract 1
- 229910000359 iron(II) sulfate Inorganic materials 0.000 abstract 1
- 239000006210 lotion Substances 0.000 abstract 1
- 235000010603 pastilles Nutrition 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 description 24
- 102000004190 Enzymes Human genes 0.000 description 24
- 229940088598 enzyme Drugs 0.000 description 24
- 230000000694 effects Effects 0.000 description 13
- 208000002925 dental caries Diseases 0.000 description 12
- 239000003795 chemical substances by application Substances 0.000 description 11
- 238000000338 in vitro Methods 0.000 description 5
- 208000027418 Wounds and injury Diseases 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 208000006558 Dental Calculus Diseases 0.000 description 3
- 241000282412 Homo Species 0.000 description 3
- AYRXSINWFIIFAE-SCLMCMATSA-N Isomaltose Natural products OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)[C@@H](O)[C@@H](O)[C@@H]1O AYRXSINWFIIFAE-SCLMCMATSA-N 0.000 description 3
- -1 amylopsin Proteins 0.000 description 3
- 235000010633 broth Nutrition 0.000 description 3
- 230000001013 cariogenic effect Effects 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 238000000855 fermentation Methods 0.000 description 3
- 230000004151 fermentation Effects 0.000 description 3
- 238000001727 in vivo Methods 0.000 description 3
- 208000014674 injury Diseases 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000002609 medium Substances 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- 239000000758 substrate Substances 0.000 description 3
- 239000007640 basal medium Substances 0.000 description 2
- 210000004513 dentition Anatomy 0.000 description 2
- 230000002255 enzymatic effect Effects 0.000 description 2
- IINNWAYUJNWZRM-UHFFFAOYSA-L erythrosin B Chemical compound [Na+].[Na+].[O-]C(=O)C1=CC=CC=C1C1=C2C=C(I)C(=O)C(I)=C2OC2=C(I)C([O-])=C(I)C=C21 IINNWAYUJNWZRM-UHFFFAOYSA-L 0.000 description 2
- 229940011411 erythrosine Drugs 0.000 description 2
- 235000012732 erythrosine Nutrition 0.000 description 2
- 239000004174 erythrosine Substances 0.000 description 2
- 238000011534 incubation Methods 0.000 description 2
- DLRVVLDZNNYCBX-RTPHMHGBSA-N isomaltose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)C(O)O1 DLRVVLDZNNYCBX-RTPHMHGBSA-N 0.000 description 2
- 238000012423 maintenance Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 235000000346 sugar Nutrition 0.000 description 2
- 230000036346 tooth eruption Effects 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 1
- 241000228212 Aspergillus Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000699800 Cricetinae Species 0.000 description 1
- 206010061217 Infestation Diseases 0.000 description 1
- 241000364057 Peoria Species 0.000 description 1
- 102000057297 Pepsin A Human genes 0.000 description 1
- 108090000284 Pepsin A Proteins 0.000 description 1
- 241000733634 Prionosciadium lilacinum Species 0.000 description 1
- 208000014151 Stomatognathic disease Diseases 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 241000194022 Streptococcus sp. Species 0.000 description 1
- 241001516650 Talaromyces verruculosus Species 0.000 description 1
- 102000004142 Trypsin Human genes 0.000 description 1
- 108090000631 Trypsin Proteins 0.000 description 1
- 208000016599 Uterine disease Diseases 0.000 description 1
- 239000008351 acetate buffer Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000000502 dialysis Methods 0.000 description 1
- 229940079919 digestives enzyme preparation Drugs 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 150000004673 fluoride salts Chemical class 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 238000004362 fungal culture Methods 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000009629 microbiological culture Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229940111202 pepsin Drugs 0.000 description 1
- 230000003239 periodontal effect Effects 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000007790 scraping Methods 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 108091016642 steapsin Proteins 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65667167A | 1967-07-28 | 1967-07-28 | |
| US70187568A | 1968-01-31 | 1968-01-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH512244A true CH512244A (de) | 1971-09-15 |
Family
ID=27097233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1109468A CH512244A (de) | 1967-07-28 | 1968-07-24 | Mittel zur Erhaltung der Mundhygiene |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JPS4834897B1 (pm) |
| AT (1) | AT303972B (pm) |
| BE (1) | BE718645A (pm) |
| CA (1) | CA945072A (pm) |
| CH (1) | CH512244A (pm) |
| DK (1) | DK120449B (pm) |
| FI (1) | FI46807C (pm) |
| FR (2) | FR1584054A (pm) |
| IL (1) | IL30362A0 (pm) |
| NL (1) | NL148236B (pm) |
| PH (1) | PH9638A (pm) |
| SE (1) | SE364182B (pm) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10237317B4 (de) | 2002-08-15 | 2010-04-08 | 3M Espe Ag | Enzymhaltige Zusammensetzung, Verfahren zu deren Herstellung und deren Verwendung |
| EP1600141B1 (en) | 2004-05-24 | 2013-04-17 | 3M Deutschland GmbH | Collagenolytic active enzyme containing compositions for the treatment of dental caries |
-
1968
- 1968-07-09 NL NL686809687A patent/NL148236B/xx unknown
- 1968-07-15 IL IL6830362A patent/IL30362A0/xx unknown
- 1968-07-17 FI FI682033A patent/FI46807C/fi active
- 1968-07-19 CA CA125,656A patent/CA945072A/en not_active Expired
- 1968-07-24 CH CH1109468A patent/CH512244A/de not_active IP Right Cessation
- 1968-07-25 JP JP43052195A patent/JPS4834897B1/ja active Pending
- 1968-07-25 SE SE10142/68A patent/SE364182B/xx unknown
- 1968-07-26 FR FR160833A patent/FR1584054A/fr not_active Expired
- 1968-07-26 AT AT730868A patent/AT303972B/de not_active IP Right Cessation
- 1968-07-26 DK DK362268AA patent/DK120449B/da not_active IP Right Cessation
- 1968-07-26 FR FR160831A patent/FR7748M/fr not_active Expired
- 1968-07-26 BE BE718645A patent/BE718645A/xx unknown
-
1971
- 1971-12-14 PH PH13104*UA patent/PH9638A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL30362A0 (en) | 1968-09-26 |
| CA945072A (en) | 1974-04-09 |
| SE364182B (pm) | 1974-02-18 |
| PH9638A (en) | 1976-01-22 |
| FR7748M (fr) | 1970-03-16 |
| FI46807B (pm) | 1973-04-02 |
| FR1584054A (fr) | 1969-12-12 |
| NL148236B (nl) | 1976-01-15 |
| DK120449B (da) | 1971-06-01 |
| AT303972B (de) | 1972-12-27 |
| JPS4834897B1 (pm) | 1973-10-24 |
| FI46807C (fi) | 1973-07-10 |
| BE718645A (pm) | 1969-01-27 |
| NL6809687A (pm) | 1969-01-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |