CH507224A - Verfahren zur Herstellung von 7(a und B)-Methyl-3B-hydroxy-5-androstenen, 2a,7(a und B)-Dimethyl-3B-hydroxy-5-androstenen sowie deren 19-Nor-Derivaten - Google Patents

Verfahren zur Herstellung von 7(a und B)-Methyl-3B-hydroxy-5-androstenen, 2a,7(a und B)-Dimethyl-3B-hydroxy-5-androstenen sowie deren 19-Nor-Derivaten

Info

Publication number
CH507224A
CH507224A CH391566A CH391566A CH507224A CH 507224 A CH507224 A CH 507224A CH 391566 A CH391566 A CH 391566A CH 391566 A CH391566 A CH 391566A CH 507224 A CH507224 A CH 507224A
Authority
CH
Switzerland
Prior art keywords
methyl
dimethyl
hydroxy
group
dihydroxy
Prior art date
Application number
CH391566A
Other languages
German (de)
English (en)
Inventor
Campbell J Allan
Claude Babcock John
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US00446395A external-priority patent/US3846456A/en
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of CH507224A publication Critical patent/CH507224A/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH391566A 1965-04-07 1966-03-18 Verfahren zur Herstellung von 7(a und B)-Methyl-3B-hydroxy-5-androstenen, 2a,7(a und B)-Dimethyl-3B-hydroxy-5-androstenen sowie deren 19-Nor-Derivaten CH507224A (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US446396A US3380886A (en) 1965-04-07 1965-04-07 7alpha-methyl-3beta-hydroxy-5-androstenes
US00446395A US3846456A (en) 1965-04-07 1965-04-07 Organic compounds

Publications (1)

Publication Number Publication Date
CH507224A true CH507224A (de) 1971-05-15

Family

ID=27034609

Family Applications (2)

Application Number Title Priority Date Filing Date
CH391566A CH507224A (de) 1965-04-07 1966-03-18 Verfahren zur Herstellung von 7(a und B)-Methyl-3B-hydroxy-5-androstenen, 2a,7(a und B)-Dimethyl-3B-hydroxy-5-androstenen sowie deren 19-Nor-Derivaten
CH433166A CH490359A (de) 1965-04-07 1968-03-25 Verfahren zur Herstellung von Steroid-Verbindungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH433166A CH490359A (de) 1965-04-07 1968-03-25 Verfahren zur Herstellung von Steroid-Verbindungen

Country Status (8)

Country Link
US (1) US3380886A (US07122603-20061017-C00294.png)
BE (2) BE679218A (US07122603-20061017-C00294.png)
CH (2) CH507224A (US07122603-20061017-C00294.png)
DE (1) DE1593621A1 (US07122603-20061017-C00294.png)
FR (2) FR5612M (US07122603-20061017-C00294.png)
GB (3) GB1146991A (US07122603-20061017-C00294.png)
IL (2) IL25391A (US07122603-20061017-C00294.png)
NL (2) NL6604607A (US07122603-20061017-C00294.png)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7501563A (nl) * 1974-02-28 1975-09-01 Merck & Co Inc Werkwijze voor het bereiden van preparaten te- gen het samenpakken van bloedplaatjes.
US4297350A (en) * 1978-10-10 1981-10-27 The Upjohn Company Male contraceptive steroids and methods of use
US4898694A (en) * 1987-11-25 1990-02-06 Schwartz Arthur G 17-Hydroxy-steroids
US5227375A (en) * 1990-02-08 1993-07-13 Endorecherche, Inc. Aromatase inhibitors
IT1277700B1 (it) * 1995-12-22 1997-11-11 Poli Ind Chimica Spa Processo di preparazione di 2-beta, 16-beta-diamino 3-alfa, 17-beta- diacilossi 5-alfaandrostani, bloccanti neuromuscolari a struttura
US6667299B1 (en) * 2000-03-16 2003-12-23 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical compositions and treatment methods
AU2002211563A1 (en) * 2000-10-06 2002-04-15 Aeson Therapeutics Inc. Compounds useful for treating hypertriglyceridemia
US20220169672A1 (en) * 2019-02-28 2022-06-02 Purdue Research Foundation Compounds for targeted therapies of castration resistant prostate cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3262949A (en) * 1956-11-13 1966-07-26 Syntex Corp 7-methyl androstane compounds
US3145221A (en) * 1957-11-27 1964-08-18 Syntex Corp 17alpha-lower alkyl, 17alpha-lower alkinyl and 17alpha-lower alkenyl derivatives of 19-nor-delta5-androsten-17beta-ol-3-one
US3029263A (en) * 1959-12-24 1962-04-10 Upjohn Co 7-methyl-4, 6-androstadienes
US3246021A (en) * 1960-04-20 1966-04-12 Merck & Co Inc Intermediates in the preparation of 6beta-methyl-halo ethisterone compounds
DE1249264B (de) * 1962-08-24 1967-09-07 The British Drug Houses Limited London Verfahren zur Her Stellung von neuen YIi Chlorathmyl 17ß alkoxysteroiden

Also Published As

Publication number Publication date
GB1146053A (en) 1969-03-19
IL25391A (en) 1970-01-29
DE1593613B2 (de) 1976-01-15
FR5612M (US07122603-20061017-C00294.png) 1967-12-11
NL6604606A (US07122603-20061017-C00294.png) 1966-10-10
NL6604607A (US07122603-20061017-C00294.png) 1966-10-10
CH490359A (de) 1970-05-15
FR5794M (US07122603-20061017-C00294.png) 1968-02-12
DE1593621A1 (de) 1970-05-27
IL25403A (en) 1970-07-19
BE679215A (US07122603-20061017-C00294.png) 1966-10-07
GB1146992A (en) 1969-03-26
DE1593613A1 (de) 1970-08-13
US3380886A (en) 1968-04-30
GB1146991A (en) 1969-03-26
BE679218A (US07122603-20061017-C00294.png) 1966-10-07

Similar Documents

Publication Publication Date Title
CH507224A (de) Verfahren zur Herstellung von 7(a und B)-Methyl-3B-hydroxy-5-androstenen, 2a,7(a und B)-Dimethyl-3B-hydroxy-5-androstenen sowie deren 19-Nor-Derivaten
CH561739A5 (en) 4-Hydroxy-2-butenoic acid lactone steroid derivs - cardiotonic, anti-inflammatory, hypocholesterolaemic, mineralocorticoid agents
DE1468035A1 (de) Verfahren zur Herstellung von 19-Alkylsteroiden
DE1793633C3 (de) Verfahren zur Herstellung von Gona 4(5),9(10)dien3 onen Ausscheidung aus 1468642
DE2037402A1 (de) Verfahren zur Herstellung von 7 alpha Methylsteroiddenvaten
DE1468985A1 (de) 17alpha-Alkyl-,17alpha-Alkenyl- und 17alpha-Alkinyl-4,5-epoxy-19-norandrostan-17beta-diole und deren Carbonsaeureester sowie Verfahren zur Herstellung dieser Verbindungen
DE1568175C3 (de) 17 alpha-Alka-1 ',3-diinylsteroide und Verfahren zu ihrer Herstellung
DE1793749C3 (de) Verfahren zur Herstellung von 1,4-Diensteroiden
DE1264441B (de) Verfahren zur Herstellung von 17alpha-AEthinyl-delta 5(10-19-nor-androsten-17beta-ol-3-on und 17alpha-AEthynil-19-nor-testosteron sowie dessen Estern
DE1593613C3 (de) 7 (alpha und beta)-Methyl-androstenderivate und Verfahren zu deren Herstellung
DE1236501B (de) Verfahren zur Herstellung von 10alpha- und 9beta, 10alpha-Steroiden der Androstan- bzw. Pregnanreihe
AT226383B (de) Verfahren zur Herstellung von neuen Steroidverbindungen
CH495965A (de) Verfahren zur Herstellung von Steroiden der Östranreihe
AT248622B (de) Verfahren zur Herstellung neuer 2-Cyano-3-oxo-steroide
AT221723B (de) Verfahren zur Herstellung therapeutisch wertvoller Carbonsäureester von 17-Alkyl-19-nor-testosteronen
DE2222544C3 (de) Neue 16,17-Secoöstradi- und triene Verfahren zu ihrer Herstellung sowie diese enthaltendes Mittel
AT235477B (de) Verfahren zur Herstellung von neuen, mit einem Isoxazolring kondensierten Steroidverbindungen
AT233184B (de) Verfahren zur Herstellung von 3-Oxo-Δ<1,4>-steroiden
CH390910A (de) Verfahren zur Herstellung von 19-Nor- 5-androsten-3B,17B-diolen
AT206593B (de) Verfahren zur Herstellung von 6-Methyl-3-oxo-Δ<4>-steroiden
AT232654B (de) Verfahren zur Herstellung von 16α-Methyl-17α-hydroxy-20-ketonen der Allopregnan-Reihe
DE1418945C3 (de) Verfahren zur Herstellung von 16 alpha Methyl 17alpha hydroxy 20 oxo pregnandenvaten
DE1668687B2 (de) Neue 18-methyl-5alpha-h-androstane, verfahren zu ihrer herstellung sowie diese enthaltende arzneimittel
DE1199767B (de) Verfahren zur Herstellung von 1alpha-Methyl-A2-5alpha-androsten-17beta-olen
CH497409A (de) Verfahren zur Herstellung von Steroidverbindungen der Pregnanreihe

Legal Events

Date Code Title Description
PL Patent ceased