CH501662A - Verfahren zur Herstellung von neuen Thiepinderivaten - Google Patents

Verfahren zur Herstellung von neuen Thiepinderivaten

Info

Publication number
CH501662A
CH501662A CH1808568A CH1808568A CH501662A CH 501662 A CH501662 A CH 501662A CH 1808568 A CH1808568 A CH 1808568A CH 1808568 A CH1808568 A CH 1808568A CH 501662 A CH501662 A CH 501662A
Authority
CH
Switzerland
Prior art keywords
preparation
new
thiepine
derivatives
thiepine derivatives
Prior art date
Application number
CH1808568A
Other languages
English (en)
Inventor
Walter Dr Schindler
Erich Dr Schmid
Armin Dr Zuest
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CH252968A priority Critical patent/CH493558A/de
Priority to CH962668A priority patent/CH499542A/de
Priority to CH1722968A priority patent/CH499543A/de
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Priority to CH1599070A priority patent/CH501664A/de
Priority to CH1808568A priority patent/CH501662A/de
Priority to CH159269A priority patent/CH504465A/de
Priority to FI43669A priority patent/FI48193C/fi
Priority to SE01977/69A priority patent/SE362880B/xx
Priority to NL696902286A priority patent/NL139665B/xx
Priority to NO59469A priority patent/NO122424B/no
Priority to NL696902293A priority patent/NL141195B/xx
Priority to NL696902285A priority patent/NL139748B/xx
Priority to US799954A priority patent/US3699107A/en
Priority to US799904A priority patent/US3699104A/en
Priority to US799955A priority patent/US3563993A/en
Priority to FR6904303A priority patent/FR2002327A1/fr
Priority to BE728700D priority patent/BE728700A/xx
Priority to BR20648069A priority patent/BR6906480D0/pt
Priority to BE728699D priority patent/BE728699A/xx
Priority to GB1258805D priority patent/GB1258805A/en
Priority to DE19691908545 priority patent/DE1908545A1/de
Priority to AT169769A priority patent/AT284132B/de
Priority to FR6904304A priority patent/FR2002328A1/fr
Priority to PL13184969A priority patent/PL76038B1/pl
Priority to DE19691908543 priority patent/DE1908543A1/de
Priority to FR6904302A priority patent/FR2002326A1/fr
Priority to JP1223069A priority patent/JPS4810474B1/ja
Priority to BE728701D priority patent/BE728701A/xx
Priority to IL31660A priority patent/IL31660A/en
Priority to GB1251696D priority patent/GB1251696A/en
Priority to GB1259007D priority patent/GB1259007A/en
Priority to DE19691908544 priority patent/DE1908544A1/de
Priority to IE22469A priority patent/IE33005B1/xx
Priority to ES363848A priority patent/ES363848A1/es
Publication of CH501662A publication Critical patent/CH501662A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C07D233/34—Ethylene-urea
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/22—Oxygen atoms attached in position 2 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/14—[b,f]-condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
CH1808568A 1968-02-21 1968-12-04 Verfahren zur Herstellung von neuen Thiepinderivaten CH501662A (de)

Priority Applications (34)

Application Number Priority Date Filing Date Title
CH252968A CH493558A (de) 1968-02-21 1968-02-21 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH962668A CH499542A (de) 1968-02-21 1968-06-27 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH1722968A CH499543A (de) 1968-02-21 1968-11-19 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH1599070A CH501664A (de) 1968-12-04 1968-12-04 Verfahren zur Herstellung von neuen Thiepinderivaten
CH1808568A CH501662A (de) 1968-02-21 1968-12-04 Verfahren zur Herstellung von neuen Thiepinderivaten
CH159269A CH504465A (de) 1968-02-21 1969-01-31 Verfahren zur Herstellung des 8-Chlor-10-(1-piperazinyl)-10,11-dihydro-dibenzo(b,f)thiepin
FI43669A FI48193C (fi) 1968-02-21 1969-02-12 Menetelmä uusien farmakologisesti aktiivisten 10,11-dihydrodibentso(b, f)tiepiinijohdannaisten valmistamiseksi
SE01977/69A SE362880B (de) 1968-02-21 1969-02-13
NL696902286A NL139665B (nl) 1968-02-21 1969-02-13 Werkwijze voor het bereiden van op plaats 8 gesubstitueerde 10-(1-piperazinyl) 10,11-dihydrodibenzo(b.f)thiepinederivaten.
NO59469A NO122424B (de) 1968-02-21 1969-02-13
NL696902293A NL141195B (nl) 1968-02-21 1969-02-13 Werkwijze ter bereiding van een op plaats 10 gesubstitueerd 8-chloor-10,11-dihydrodibenzo b,f thiepinederivaat en zouten daarvan, werkwijze ter bereiding van preparaten, die deze bindingen als werkzame stof bevatten en aldus verkregen gevormde preparaten.
NL696902285A NL139748B (nl) 1968-02-21 1969-02-13 Werkwijze voor het bereiden van een geneesmiddel en van farmacologisch werkzame n-gesubstitueerde 10piperazino 10,11-dihydrodibenzo (b,f) thiepienderivaten.
US799954A US3699107A (en) 1968-02-21 1969-02-17 1-(2-or 3-(4-(10,11-dihydro-dibenz(b,f)-thiepin-10-yl)-1-piperazinyl)-alkyl)-3-alkyl-2-imidazolidinone derivatives
US799904A US3699104A (en) 1968-02-21 1969-02-17 8-chloro-10-(1-piperazinyl) - 10,11 - dihydro-dibenzo(b,f)thiepin as a central nervous depressant
US799955A US3563993A (en) 1968-02-21 1969-02-17 10-(1-piperazino)-10,11-dihydro-dibenzo(b,f)thiepins
BR20648069A BR6906480D0 (pt) 1968-02-21 1969-02-20 Processo para obtencao de novos derivados de tiepina
DE19691908543 DE1908543A1 (de) 1968-02-21 1969-02-20 Verfahren zur Herstellung von neuen Thiepinderivaten
FR6904303A FR2002327A1 (de) 1968-02-21 1969-02-20
BE728699D BE728699A (de) 1968-02-21 1969-02-20
GB1258805D GB1258805A (de) 1968-02-21 1969-02-20
DE19691908545 DE1908545A1 (de) 1968-02-21 1969-02-20 Verfahren zur Herstellung von neuen Thiepinderivaten
AT169769A AT284132B (de) 1968-02-21 1969-02-20 Verfahren zur Herstellung von neuen Thiepinderivaten sowie ihrer Säureadditionssalze
FR6904304A FR2002328A1 (de) 1968-02-21 1969-02-20
PL13184969A PL76038B1 (de) 1968-02-21 1969-02-20
BE728700D BE728700A (de) 1968-02-21 1969-02-20
FR6904302A FR2002326A1 (de) 1968-02-21 1969-02-20
JP1223069A JPS4810474B1 (de) 1968-02-21 1969-02-20
BE728701D BE728701A (de) 1968-02-21 1969-02-20
IL31660A IL31660A (en) 1968-02-21 1969-02-20 Thiepine derivatives,their preparation and pharmaceutical compositions containing them
GB1251696D GB1251696A (de) 1968-02-21 1969-02-20
GB1259007D GB1259007A (de) 1968-02-21 1969-02-20
DE19691908544 DE1908544A1 (de) 1968-02-21 1969-02-20 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
IE22469A IE33005B1 (en) 1968-02-21 1969-02-20 New thiepin derivatives and a process for their production
ES363848A ES363848A1 (es) 1968-12-04 1969-02-20 Procedimiento para la preparacion de nuevos derivados de tiepina.

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CH252968A CH493558A (de) 1968-02-21 1968-02-21 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH962668A CH499542A (de) 1968-02-21 1968-06-27 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH1722968A CH499543A (de) 1968-02-21 1968-11-19 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH1808568A CH501662A (de) 1968-02-21 1968-12-04 Verfahren zur Herstellung von neuen Thiepinderivaten
CH159269A CH504465A (de) 1968-02-21 1969-01-31 Verfahren zur Herstellung des 8-Chlor-10-(1-piperazinyl)-10,11-dihydro-dibenzo(b,f)thiepin

Publications (1)

Publication Number Publication Date
CH501662A true CH501662A (de) 1971-01-15

Family

ID=27508983

Family Applications (5)

Application Number Title Priority Date Filing Date
CH252968A CH493558A (de) 1968-02-21 1968-02-21 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH962668A CH499542A (de) 1968-02-21 1968-06-27 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH1722968A CH499543A (de) 1968-02-21 1968-11-19 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH1808568A CH501662A (de) 1968-02-21 1968-12-04 Verfahren zur Herstellung von neuen Thiepinderivaten
CH159269A CH504465A (de) 1968-02-21 1969-01-31 Verfahren zur Herstellung des 8-Chlor-10-(1-piperazinyl)-10,11-dihydro-dibenzo(b,f)thiepin

Family Applications Before (3)

Application Number Title Priority Date Filing Date
CH252968A CH493558A (de) 1968-02-21 1968-02-21 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH962668A CH499542A (de) 1968-02-21 1968-06-27 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH1722968A CH499543A (de) 1968-02-21 1968-11-19 Verfahren zur Herstellung von neuen Imidazolidinonderivaten

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH159269A CH504465A (de) 1968-02-21 1969-01-31 Verfahren zur Herstellung des 8-Chlor-10-(1-piperazinyl)-10,11-dihydro-dibenzo(b,f)thiepin

Country Status (8)

Country Link
US (3) US3699107A (de)
BE (3) BE728700A (de)
CH (5) CH493558A (de)
DE (3) DE1908545A1 (de)
FR (3) FR2002328A1 (de)
GB (3) GB1251696A (de)
NL (3) NL139665B (de)
SE (1) SE362880B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1251774A (de) * 1969-03-24 1971-10-27
BE754640A (fr) * 1969-08-11 1971-02-10 Geigy Ag J R Derives de l'imidazolidinone et medicaments contenant de tels derives
CH569013A5 (de) * 1972-07-21 1975-11-14 Hoffmann La Roche
US4006144A (en) * 1972-07-21 1977-02-01 Hoffmann-La Roche Inc. 10,11-Dihydro-dibenzo(b,f)thiepin derivatives
US4006145A (en) * 1972-07-21 1977-02-01 Hoffmann-La Roche Inc. 10,11-Dihydro dibenzo(b,f)thiepin derivatives
US3954769A (en) * 1973-03-30 1976-05-04 Hoffman-La Roche Inc. Dibenzo[b,f]thiepins
US4044010A (en) * 1973-03-30 1977-08-23 Hoffmann-La Roche Inc. Dibenzo[b,f] thiepins bearing piperazinyl substitution
DE2412520C2 (de) * 1973-03-30 1982-09-16 F. Hoffmann-La Roche & Co. AG, 4002 Basel Tricyclische Verbindungen, Verfahren zu deren Herstellung und diese enthaltende Präparate
US4078063A (en) * 1976-09-24 1978-03-07 Merck & Co., Inc. Piperazinylpyridines

Also Published As

Publication number Publication date
FR2002326A1 (de) 1969-10-17
NL139665B (nl) 1973-09-17
GB1259007A (de) 1972-01-05
FR2002327A1 (de) 1969-10-17
BE728700A (de) 1969-08-20
NL6902285A (de) 1969-08-25
NL6902293A (de) 1969-08-25
CH499543A (de) 1970-11-30
GB1251696A (de) 1971-10-27
CH499542A (de) 1970-11-30
CH493558A (de) 1970-07-15
NL6902286A (de) 1969-08-25
NL139748B (nl) 1973-09-17
US3563993A (en) 1971-02-16
BE728701A (de) 1969-07-30
US3699104A (en) 1972-10-17
US3699107A (en) 1972-10-17
GB1258805A (de) 1971-12-30
FR2002328A1 (de) 1969-10-17
DE1908544A1 (de) 1970-07-02
SE362880B (de) 1973-12-27
NL141195B (nl) 1974-02-15
CH504465A (de) 1971-03-15
DE1908545A1 (de) 1970-08-06
BE728699A (de) 1969-08-20
DE1908543A1 (de) 1971-06-24

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Legal Events

Date Code Title Description
PL Patent ceased