CH504465A - Verfahren zur Herstellung des 8-Chlor-10-(1-piperazinyl)-10,11-dihydro-dibenzo(b,f)thiepin - Google Patents

Verfahren zur Herstellung des 8-Chlor-10-(1-piperazinyl)-10,11-dihydro-dibenzo(b,f)thiepin

Info

Publication number
CH504465A
CH504465A CH159269A CH159269A CH504465A CH 504465 A CH504465 A CH 504465A CH 159269 A CH159269 A CH 159269A CH 159269 A CH159269 A CH 159269A CH 504465 A CH504465 A CH 504465A
Authority
CH
Switzerland
Prior art keywords
thiepin
dibenzo
piperazinyl
dihydro
chloro
Prior art date
Application number
CH159269A
Other languages
English (en)
Inventor
Walter Dr Schindler
Erich Dr Schmid
Armin Dr Zuest
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CH252968A priority Critical patent/CH493558A/de
Priority to CH962668A priority patent/CH499542A/de
Priority to CH1722968A priority patent/CH499543A/de
Priority to CH1808568A priority patent/CH501662A/de
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Priority to CH159269A priority patent/CH504465A/de
Priority to NL696902286A priority patent/NL139665B/xx
Priority to NL696902285A priority patent/NL139748B/xx
Priority to NO59569A priority patent/NO122425B/no
Priority to SE01977/69A priority patent/SE362880B/xx
Priority to NL696902293A priority patent/NL141195B/xx
Priority to US799904A priority patent/US3699104A/en
Priority to US799954A priority patent/US3699107A/en
Priority to US799955A priority patent/US3563993A/en
Priority to ES363849A priority patent/ES363849A1/es
Priority to BG011701A priority patent/BG15034A3/bg
Priority to IE22369A priority patent/IE32968B1/xx
Priority to DE19691908544 priority patent/DE1908544A1/de
Priority to BE728699D priority patent/BE728699A/xx
Priority to GB1259007D priority patent/GB1259007A/en
Priority to DE19691908545 priority patent/DE1908545A1/de
Priority to GB1258805D priority patent/GB1258805A/en
Priority to FR6904302A priority patent/FR2002326A1/fr
Priority to FR6904303A priority patent/FR2002327A1/fr
Priority to BE728701D priority patent/BE728701A/xx
Priority to DE19691908543 priority patent/DE1908543A1/de
Priority to FR6904304A priority patent/FR2002328A1/fr
Priority to GB1251696D priority patent/GB1251696A/en
Priority to BE728700D priority patent/BE728700A/xx
Publication of CH504465A publication Critical patent/CH504465A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C07D233/34—Ethylene-urea
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/22—Oxygen atoms attached in position 2 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/14—[b,f]-condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
CH159269A 1968-02-21 1969-01-31 Verfahren zur Herstellung des 8-Chlor-10-(1-piperazinyl)-10,11-dihydro-dibenzo(b,f)thiepin CH504465A (de)

Priority Applications (28)

Application Number Priority Date Filing Date Title
CH252968A CH493558A (de) 1968-02-21 1968-02-21 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH962668A CH499542A (de) 1968-02-21 1968-06-27 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH1722968A CH499543A (de) 1968-02-21 1968-11-19 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH1808568A CH501662A (de) 1968-02-21 1968-12-04 Verfahren zur Herstellung von neuen Thiepinderivaten
CH159269A CH504465A (de) 1968-02-21 1969-01-31 Verfahren zur Herstellung des 8-Chlor-10-(1-piperazinyl)-10,11-dihydro-dibenzo(b,f)thiepin
NL696902286A NL139665B (nl) 1968-02-21 1969-02-13 Werkwijze voor het bereiden van op plaats 8 gesubstitueerde 10-(1-piperazinyl) 10,11-dihydrodibenzo(b.f)thiepinederivaten.
NL696902285A NL139748B (nl) 1968-02-21 1969-02-13 Werkwijze voor het bereiden van een geneesmiddel en van farmacologisch werkzame n-gesubstitueerde 10piperazino 10,11-dihydrodibenzo (b,f) thiepienderivaten.
NO59569A NO122425B (de) 1968-02-21 1969-02-13
SE01977/69A SE362880B (de) 1968-02-21 1969-02-13
NL696902293A NL141195B (nl) 1968-02-21 1969-02-13 Werkwijze ter bereiding van een op plaats 10 gesubstitueerd 8-chloor-10,11-dihydrodibenzo b,f thiepinederivaat en zouten daarvan, werkwijze ter bereiding van preparaten, die deze bindingen als werkzame stof bevatten en aldus verkregen gevormde preparaten.
US799904A US3699104A (en) 1968-02-21 1969-02-17 8-chloro-10-(1-piperazinyl) - 10,11 - dihydro-dibenzo(b,f)thiepin as a central nervous depressant
US799954A US3699107A (en) 1968-02-21 1969-02-17 1-(2-or 3-(4-(10,11-dihydro-dibenz(b,f)-thiepin-10-yl)-1-piperazinyl)-alkyl)-3-alkyl-2-imidazolidinone derivatives
US799955A US3563993A (en) 1968-02-21 1969-02-17 10-(1-piperazino)-10,11-dihydro-dibenzo(b,f)thiepins
ES363849A ES363849A1 (es) 1968-02-21 1969-02-20 Procedimiento para la preparacion de un nuevo derivado de tiepina.
BG011701A BG15034A3 (bg) 1968-02-21 1969-02-20 Метод за получаване на нови тиепинови деривати
IE22369A IE32968B1 (en) 1968-02-21 1969-02-20 A new thiepin derivative and process for the production thereof
DE19691908544 DE1908544A1 (de) 1968-02-21 1969-02-20 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
BE728699D BE728699A (de) 1968-02-21 1969-02-20
GB1259007D GB1259007A (de) 1968-02-21 1969-02-20
DE19691908545 DE1908545A1 (de) 1968-02-21 1969-02-20 Verfahren zur Herstellung von neuen Thiepinderivaten
GB1258805D GB1258805A (de) 1968-02-21 1969-02-20
FR6904302A FR2002326A1 (de) 1968-02-21 1969-02-20
FR6904303A FR2002327A1 (de) 1968-02-21 1969-02-20
BE728701D BE728701A (de) 1968-02-21 1969-02-20
DE19691908543 DE1908543A1 (de) 1968-02-21 1969-02-20 Verfahren zur Herstellung von neuen Thiepinderivaten
FR6904304A FR2002328A1 (de) 1968-02-21 1969-02-20
GB1251696D GB1251696A (de) 1968-02-21 1969-02-20
BE728700D BE728700A (de) 1968-02-21 1969-02-20

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CH252968A CH493558A (de) 1968-02-21 1968-02-21 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH962668A CH499542A (de) 1968-02-21 1968-06-27 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH1722968A CH499543A (de) 1968-02-21 1968-11-19 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH1808568A CH501662A (de) 1968-02-21 1968-12-04 Verfahren zur Herstellung von neuen Thiepinderivaten
CH159269A CH504465A (de) 1968-02-21 1969-01-31 Verfahren zur Herstellung des 8-Chlor-10-(1-piperazinyl)-10,11-dihydro-dibenzo(b,f)thiepin

Publications (1)

Publication Number Publication Date
CH504465A true CH504465A (de) 1971-03-15

Family

ID=27508983

Family Applications (5)

Application Number Title Priority Date Filing Date
CH252968A CH493558A (de) 1968-02-21 1968-02-21 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH962668A CH499542A (de) 1968-02-21 1968-06-27 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH1722968A CH499543A (de) 1968-02-21 1968-11-19 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH1808568A CH501662A (de) 1968-02-21 1968-12-04 Verfahren zur Herstellung von neuen Thiepinderivaten
CH159269A CH504465A (de) 1968-02-21 1969-01-31 Verfahren zur Herstellung des 8-Chlor-10-(1-piperazinyl)-10,11-dihydro-dibenzo(b,f)thiepin

Family Applications Before (4)

Application Number Title Priority Date Filing Date
CH252968A CH493558A (de) 1968-02-21 1968-02-21 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH962668A CH499542A (de) 1968-02-21 1968-06-27 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH1722968A CH499543A (de) 1968-02-21 1968-11-19 Verfahren zur Herstellung von neuen Imidazolidinonderivaten
CH1808568A CH501662A (de) 1968-02-21 1968-12-04 Verfahren zur Herstellung von neuen Thiepinderivaten

Country Status (8)

Country Link
US (3) US3563993A (de)
BE (3) BE728700A (de)
CH (5) CH493558A (de)
DE (3) DE1908543A1 (de)
FR (3) FR2002326A1 (de)
GB (3) GB1258805A (de)
NL (3) NL139748B (de)
SE (1) SE362880B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1251774A (de) * 1969-03-24 1971-10-27
BE754640A (fr) * 1969-08-11 1971-02-10 Geigy Ag J R Derives de l'imidazolidinone et medicaments contenant de tels derives
US4006144A (en) * 1972-07-21 1977-02-01 Hoffmann-La Roche Inc. 10,11-Dihydro-dibenzo(b,f)thiepin derivatives
CH569013A5 (de) * 1972-07-21 1975-11-14 Hoffmann La Roche
US4006145A (en) * 1972-07-21 1977-02-01 Hoffmann-La Roche Inc. 10,11-Dihydro dibenzo(b,f)thiepin derivatives
US3954769A (en) * 1973-03-30 1976-05-04 Hoffman-La Roche Inc. Dibenzo[b,f]thiepins
US4044010A (en) * 1973-03-30 1977-08-23 Hoffmann-La Roche Inc. Dibenzo[b,f] thiepins bearing piperazinyl substitution
DE2412520C2 (de) * 1973-03-30 1982-09-16 F. Hoffmann-La Roche & Co. AG, 4002 Basel Tricyclische Verbindungen, Verfahren zu deren Herstellung und diese enthaltende Präparate
US4078063A (en) * 1976-09-24 1978-03-07 Merck & Co., Inc. Piperazinylpyridines

Also Published As

Publication number Publication date
BE728701A (de) 1969-07-30
BE728700A (de) 1969-08-20
DE1908543A1 (de) 1971-06-24
GB1259007A (de) 1972-01-05
DE1908545A1 (de) 1970-08-06
NL6902286A (de) 1969-08-25
SE362880B (de) 1973-12-27
GB1251696A (de) 1971-10-27
CH499542A (de) 1970-11-30
US3563993A (en) 1971-02-16
NL139748B (nl) 1973-09-17
US3699107A (en) 1972-10-17
NL139665B (nl) 1973-09-17
NL141195B (nl) 1974-02-15
BE728699A (de) 1969-08-20
US3699104A (en) 1972-10-17
CH499543A (de) 1970-11-30
NL6902285A (de) 1969-08-25
FR2002328A1 (de) 1969-10-17
CH493558A (de) 1970-07-15
CH501662A (de) 1971-01-15
FR2002326A1 (de) 1969-10-17
GB1258805A (de) 1971-12-30
NL6902293A (de) 1969-08-25
FR2002327A1 (de) 1969-10-17
DE1908544A1 (de) 1970-07-02

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Legal Events

Date Code Title Description
PL Patent ceased