CH490087A - Verfahren zur Herstellung von stabilen, für die parenterale, perorale und lokale Verabreichung geeigneten wässrigen Oxytetracyclinlösungen - Google Patents

Verfahren zur Herstellung von stabilen, für die parenterale, perorale und lokale Verabreichung geeigneten wässrigen Oxytetracyclinlösungen

Info

Publication number
CH490087A
CH490087A CH766867A CH766867A CH490087A CH 490087 A CH490087 A CH 490087A CH 766867 A CH766867 A CH 766867A CH 766867 A CH766867 A CH 766867A CH 490087 A CH490087 A CH 490087A
Authority
CH
Switzerland
Prior art keywords
peroral
parenteral
preparation
local administration
stable aqueous
Prior art date
Application number
CH766867A
Other languages
German (de)
English (en)
Original Assignee
Koninklijke Gist Spiritus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Gist Spiritus filed Critical Koninklijke Gist Spiritus
Publication of CH490087A publication Critical patent/CH490087A/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79—Polymers of vinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CH766867A 1966-05-31 1967-05-31 Verfahren zur Herstellung von stabilen, für die parenterale, perorale und lokale Verabreichung geeigneten wässrigen Oxytetracyclinlösungen CH490087A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL6607516A NL6607516A (en:Method) 1966-05-31 1966-05-31

Publications (1)

Publication Number Publication Date
CH490087A true CH490087A (de) 1970-05-15

Family

ID=19796753

Family Applications (1)

Application Number Title Priority Date Filing Date
CH766867A CH490087A (de) 1966-05-31 1967-05-31 Verfahren zur Herstellung von stabilen, für die parenterale, perorale und lokale Verabreichung geeigneten wässrigen Oxytetracyclinlösungen

Country Status (22)

Country Link
US (1) US3557280A (en:Method)
JP (1) JPS5010373B1 (en:Method)
AT (1) AT272522B (en:Method)
BE (1) BE699091A (en:Method)
CH (1) CH490087A (en:Method)
CS (1) CS151454B2 (en:Method)
DE (1) DE1617576C3 (en:Method)
DK (1) DK117587B (en:Method)
ES (1) ES340956A1 (en:Method)
FI (1) FI43622B (en:Method)
FR (1) FR5953M (en:Method)
GB (1) GB1131007A (en:Method)
GR (1) GR33861B (en:Method)
IL (1) IL28009A (en:Method)
IT (1) IT1140250B (en:Method)
LU (1) LU53788A1 (en:Method)
MY (1) MY7100015A (en:Method)
NL (1) NL6607516A (en:Method)
NO (1) NO126298B (en:Method)
SE (1) SE354417B (en:Method)
SU (1) SU510986A3 (en:Method)
YU (1) YU31326B (en:Method)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5418330B2 (en:Method) * 1973-03-16 1979-07-06
US3966905A (en) * 1973-05-29 1976-06-29 Barnes-Hind Pharmaceuticals, Inc. Stabilized catechol amine solutions
US3929989A (en) * 1974-06-14 1975-12-30 Wendt Lab Inc Stable suspension of calcium-magnesium oxytetracycline for intrauterine administration in treatment of bovine metritis
GB1538903A (en) * 1975-04-11 1979-01-24 Nelson Res & Dev Carrier for a topically applied physiologically active agent or cosmetic agent
US4018889A (en) * 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
DE2602363C2 (de) * 1976-01-22 1984-04-12 Bayer Ag, 5090 Leverkusen Wäßrige, injizierbare Niclofolan- Formulierungen
GB1592053A (en) * 1976-12-16 1981-07-01 Norbrook Lab Ltd Oxytetracycline compositions
US4213963A (en) * 1978-12-14 1980-07-22 Janssen Pharmaceutica N.V. Fluspirilene-containing compositions
US4259331A (en) * 1979-04-16 1981-03-31 Pfizer Inc. Oxytetracycline compositions
US4399127A (en) * 1980-04-10 1983-08-16 Diamond Shamrock Corporation Injectable oxytetracycline compositions
US4386083A (en) * 1980-04-10 1983-05-31 Walter Hacke Injectable oxytetracycline compositions
IE74244B1 (en) * 1985-10-01 1997-07-16 Bimeda Res Dev Ltd A process for preparing an antibiotic composition
US5071643A (en) * 1986-10-17 1991-12-10 R. P. Scherer Corporation Solvent system enhancing the solubility of pharmaceuticals for encapsulation
US6756365B2 (en) * 1991-11-06 2004-06-29 Trustees Of Tufts College Reducing tetracycline resistance in living cells
EP0626171A1 (de) * 1993-05-26 1994-11-30 Winfried Dörnhöfer Injektionslösung für die intravenöse oder intramuskuläre Verabreichung an Tiere
US6383515B2 (en) 1999-05-28 2002-05-07 Sawyer Maryjean Solvent system for enhancing solubility
US6500812B2 (en) 1999-09-14 2002-12-31 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
US6849615B2 (en) 1999-09-14 2005-02-01 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
EP1666453A1 (en) * 1999-09-14 2006-06-07 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
US8106225B2 (en) * 1999-09-14 2012-01-31 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
WO2001052858A1 (en) 2000-01-24 2001-07-26 Trustees Of Tufts College Tetracycline compounds for treatment of cryptosporidium parvum related disorders
AU2001251157A1 (en) * 2000-03-31 2001-10-15 Paratek Pharmaceuticals, Inc 7-and 9-carbamate, urea, thiourea, thiocarbamate, and heteroaryl-amino substituted tetracycline compounds
CA2409063A1 (en) 2000-05-15 2001-11-22 Mark L. Nelson 7-substituted fused ring tetracycline compounds
US20020128238A1 (en) * 2000-06-16 2002-09-12 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
US20020132798A1 (en) * 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
US20040224927A1 (en) 2000-06-16 2004-11-11 Trustees Of Tufts College 7-N-substituted phenyl tetracycline compounds
US20050143353A1 (en) * 2000-07-07 2005-06-30 Paratek Pharmaceuticals, Inc. 13-Substituted methacycline compounds
EP1301465A2 (en) 2000-07-07 2003-04-16 Trustees Of Tufts College 13-substituted methacycline compounds
CA2415718C (en) * 2000-07-07 2012-08-28 Trustees Of Tufts College 7-substituted tetracycline compounds
US7094806B2 (en) * 2000-07-07 2006-08-22 Trustees Of Tufts College 7, 8 and 9-substituted tetracycline compounds
WO2002004404A2 (en) 2000-07-07 2002-01-17 Trustees Of Tufts College 7,8 and 9-substituted tetracycline compounds
HU229577B1 (en) 2000-07-07 2014-02-28 Tufts College 9-substituted minocycline derivatives
HUP0402047A3 (en) 2001-03-13 2012-10-29 Paratek Pharmaceuticals 7,9-substituted tetracycline compounds, their use and pharmaceutical compositions containing them
AU2002250331A1 (en) * 2001-03-13 2002-09-24 Paratek Pharmaceuticals, Inc. 7-pyrollyl tetracycline compounds and methods of use thereof
WO2002072031A2 (en) 2001-03-14 2002-09-19 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds as synergistic antifungal agents
WO2002072022A2 (en) 2001-03-14 2002-09-19 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds as antifungal agents
US8088820B2 (en) * 2001-04-24 2012-01-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
ES2338994T3 (es) 2001-04-24 2010-05-14 Paratek Pharmaceuticals, Inc. Compuestos de tetraciclina sustituida para el tratamiento de la malaria.
WO2003057169A2 (en) 2002-01-08 2003-07-17 Paratek Pharmaceuticals, Inc. 4-dedimethylamino tetracycline compounds
EA200802365A1 (ru) 2002-03-08 2009-08-28 Паратек Фармасьютикалс, Инк. Аминометилзамещенные тетрациклиновые соединения
CN101712632A (zh) 2002-03-21 2010-05-26 帕拉特克药品公司 取代的四环素化合物
CA2492273C (en) 2002-07-12 2013-02-05 Paratek Pharmaceuticals, Inc. 3, 10, and 12a substituted tetracycline compounds
EP2277504A1 (en) 2002-10-24 2011-01-26 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
WO2004071490A1 (en) * 2003-02-12 2004-08-26 R & P Korea Co., Ltd. Solvent system of hardly soluble drug with improved elution rate
US20060287283A1 (en) * 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
AU2004259659B2 (en) 2003-07-09 2011-11-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
US20050137174A1 (en) 2003-07-09 2005-06-23 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
CA2553510C (en) * 2004-01-15 2012-09-25 Paratek Pharmaceuticals, Inc. Aromatic a-ring derivatives of tetracycline compounds
TWI261038B (en) * 2004-08-11 2006-09-01 Bo-Cheng Chen Bicycle gear-shifting handgrip
EP2269978A3 (en) 2004-10-25 2011-09-21 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
WO2006047671A2 (en) * 2004-10-25 2006-05-04 Paratek Pharmaceuticals, Inc. 4-aminotetracyclines and methods of use thereof
EP1848685A1 (en) 2005-02-04 2007-10-31 Paratek Pharmaceuticals, Inc. 11a, 12-derivatives of tetracycline compounds
DE102005012595A1 (de) * 2005-03-18 2006-09-21 Lanxess Deutschland Gmbh Herstellung von Tri(chlorpropyl)phosphat
CA2616224A1 (en) * 2005-07-21 2007-02-01 Paratek Pharmaceuticals, Inc. 10-substituted tetracyclines and methods of use thereof
CA2622704A1 (en) * 2005-09-19 2007-03-29 Albemarle Corporation Highly concentrated pourable aqueous solutions of potassium ibuprofen their preparation and their uses
AU2007208214B2 (en) 2006-01-24 2013-02-14 Paratek Pharmaceuticals, Inc. Methods of increasing oral bioavailability of tetracyclines
WO2007120913A2 (en) * 2006-04-17 2007-10-25 Teva Pharmaceutical Industries Ltd. Isolation of tetracycline derivatives
US8198470B2 (en) * 2006-04-24 2012-06-12 Teva Pharmaceutical Industries Ltd. Crystalline form II of tigecycline and processes for preparation thereof
EP2857386B1 (en) * 2006-04-24 2017-02-22 Teva Pharmaceutical Industries Ltd Tigecycline crystalline forms and processes for preparation thereof
JP2009543544A (ja) * 2006-05-15 2009-12-10 パラテック ファーマシューティカルズ インコーポレイテッド 置換されたテトラサイクリン化合物を用いて、遺伝子または遺伝子産物の発現を調節する方法
WO2008045507A2 (en) 2006-10-11 2008-04-17 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of bacillus anthracis infections
PL2120963T3 (pl) 2006-12-21 2019-05-31 Paratek Pharm Innc Podstawione związki tetracyklinowe do leczenia zaburzeń zapalnych skóry
EP3812372A3 (en) 2006-12-21 2021-06-30 Paratek Pharmaceuticals, Inc. 7-heterocyclyl substituted sancycline derivatives for treating bacterial, viral and parasitic infections (e.g. malaria) or inflammatory diseases
AU2008239606A1 (en) * 2007-04-12 2008-10-23 Paratek Pharmaceuticals, Inc. Methods for treating spinal muscular atrophy using tetracycline compounds
US9434680B2 (en) 2007-04-27 2016-09-06 Paratek Pharmaceuticals, Inc. Methods for synthesizing and purifying aminoalkyl tetracycline compounds
US9522872B2 (en) 2007-07-06 2016-12-20 Paratek Pharmaceuticals, Inc. Methods for synthesizing substituted tetracycline compounds
KR20100126469A (ko) 2008-03-05 2010-12-01 파라테크 파마슈티컬스, 인크. 미노사이클린 화합물 및 이들의 사용 방법
PT2271348T (pt) 2008-03-28 2018-04-16 Paratek Pharm Innc Formulação de comprimido oral de composto de tetraciclina
US20100022483A1 (en) * 2008-04-14 2010-01-28 Paratek Pharmaceuticals, Inc. Substituted Tetracycline Compounds
TW202021946A (zh) 2008-05-19 2020-06-16 美商派洛泰克藥物股份有限公司 四環素化合物之甲苯磺酸鹽及同素異形體
BRPI0916344A2 (pt) 2008-07-21 2020-07-21 Albemarle Corporation grânulos com alto teor de ibuprofeno de sódio, preparação e utilização para preparação de formas de dosagem sólidas não efervescentes
US9629809B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
AP2011005631A0 (en) * 2008-09-19 2011-04-30 Paratek Pharmaceuticals Ind Tetracycline compounds for the treatment of rheumatoid arthritis and related methods of treatment.
AU2010233089B2 (en) 2009-04-10 2016-05-26 Tufts Medical Center, Inc. Par-1 activation by metalloproteinase-1 (MMP-1)
PL2707003T3 (pl) 2011-05-12 2019-11-29 Paratek Pharm Innc Krystaliczne sole amidu kwasu (4s,4as,5ar,12as)-4-dimetyloamino-3,10,12,12a-tetrahydroksy-7-[(metoksy(metylo)amino)metylo]-1,11-diokso- 1,4,4a,5,5a,6,11,12a-oktahydronaftaceno- 2-karboksylowego i sposoby ich stosowania
AU2017353588B2 (en) 2016-11-01 2022-07-14 Paratek Pharmaceuticals, Inc. 9-aminomethyl minocycline compounds and use thereof in treating Community-Acquired Bacterial Pneumonia (CABP)
US20200222432A1 (en) 2017-07-21 2020-07-16 Almirall, Llc. Treatment of non-inflammatory lesions

Also Published As

Publication number Publication date
YU31326B (en) 1973-04-30
SE354417B (en:Method) 1973-03-12
NO126298B (en:Method) 1973-01-22
GB1131007A (en) 1968-10-16
FR5953M (en:Method) 1968-04-16
IL28009A (en) 1970-08-19
GR33861B (el) 1968-02-09
DE1617576C3 (de) 1980-12-11
DK117587B (da) 1970-05-11
DE1617576A1 (de) 1972-04-27
NL6607516A (en:Method) 1967-12-01
US3557280A (en) 1971-01-19
ES340956A1 (es) 1968-06-16
MY7100015A (en) 1971-12-31
IT1140250B (it) 1986-09-24
JPS5010373B1 (en:Method) 1975-04-21
CS151454B2 (en:Method) 1973-10-19
SU510986A3 (ru) 1976-04-15
LU53788A1 (en:Method) 1967-07-31
FI43622B (en:Method) 1971-02-01
DE1617576B2 (de) 1980-04-10
BE699091A (en:Method) 1967-11-27
AT272522B (de) 1969-07-10

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