CH479535A - Verfahren zur Herstellung von a-Alkyl-l-adamantanmethylaminen und a-Alkyl-3-tricyclo(4,3,1,1 3,8)undecanmethylaminen - Google Patents

Verfahren zur Herstellung von a-Alkyl-l-adamantanmethylaminen und a-Alkyl-3-tricyclo(4,3,1,1 3,8)undecanmethylaminen

Info

Publication number
CH479535A
CH479535A CH1457468A CH1457468A CH479535A CH 479535 A CH479535 A CH 479535A CH 1457468 A CH1457468 A CH 1457468A CH 1457468 A CH1457468 A CH 1457468A CH 479535 A CH479535 A CH 479535A
Authority
CH
Switzerland
Prior art keywords
methylamines
alkyl
tricyclo
adamantane
undecane
Prior art date
Application number
CH1457468A
Other languages
German (de)
English (en)
Inventor
W Prichard William
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of CH479535A publication Critical patent/CH479535A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/29Saturated compounds containing keto groups bound to rings
    • C07C49/313Saturated compounds containing keto groups bound to rings polycyclic
    • C07C49/323Saturated compounds containing keto groups bound to rings polycyclic having keto groups bound to condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/56Ring systems containing bridged rings
    • C07C2603/58Ring systems containing bridged rings containing three rings
    • C07C2603/70Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74Adamantanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH1457468A 1963-07-24 1964-07-20 Verfahren zur Herstellung von a-Alkyl-l-adamantanmethylaminen und a-Alkyl-3-tricyclo(4,3,1,1 3,8)undecanmethylaminen CH479535A (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29723363A 1963-07-24 1963-07-24
US376259A US3352912A (en) 1963-07-24 1964-06-18 Adamantanes and tricyclo[4. 3. 1. 1 3.8] undecanes

Publications (1)

Publication Number Publication Date
CH479535A true CH479535A (de) 1969-10-15

Family

ID=26970055

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1457468A CH479535A (de) 1963-07-24 1964-07-20 Verfahren zur Herstellung von a-Alkyl-l-adamantanmethylaminen und a-Alkyl-3-tricyclo(4,3,1,1 3,8)undecanmethylaminen
CH946964A CH476673A (de) 1963-07-24 1964-07-20 Verfahren zur Herstellung von Salzen von Adamantan- und Tricyclo(4,3,1,13,8)undecanverbindungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH946964A CH476673A (de) 1963-07-24 1964-07-20 Verfahren zur Herstellung von Salzen von Adamantan- und Tricyclo(4,3,1,13,8)undecanverbindungen

Country Status (14)

Country Link
US (1) US3352912A (enrdf_load_html_response)
AT (1) AT279581B (enrdf_load_html_response)
BE (1) BE650919A (enrdf_load_html_response)
BR (1) BR6460975D0 (enrdf_load_html_response)
CH (2) CH479535A (enrdf_load_html_response)
DE (3) DE1792295B1 (enrdf_load_html_response)
DK (3) DK112027B (enrdf_load_html_response)
ES (1) ES302369A1 (enrdf_load_html_response)
FI (3) FI42322B (enrdf_load_html_response)
FR (1) FR1572956A (enrdf_load_html_response)
GB (1) GB1069563A (enrdf_load_html_response)
IL (1) IL21753A (enrdf_load_html_response)
NL (2) NL6408505A (enrdf_load_html_response)
SE (3) SE330693B (enrdf_load_html_response)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3449422A (en) * 1966-02-09 1969-06-10 Smithkline Corp Pentacycloundecane amines
DE1294371B (de) * 1966-12-21 1969-05-08 Penicillin Ges Dauelsberg & Co Verfahren zur Herstellung von 1-Aminoadamantan und dessen N-Alkyl- bzw. N-Cyclohexylderivaten
US3489802A (en) * 1967-01-23 1970-01-13 Du Pont Preparation of alpha-methyl-1-adamantane-methylamine and alpha,4 - dimethyl - 1 - bicyclo(2,2,2)octane methylamine
NL6900004A (enrdf_load_html_response) * 1969-01-02 1970-07-06
US3682922A (en) * 1969-01-16 1972-08-08 Searle & Co N-acyl-n-{8 (n{40 ,n{40 -disubstituted amino)-alkyl{9 -1-adamantylmethylamines
JPS4828903B1 (enrdf_load_html_response) * 1969-07-19 1973-09-05
US3624086A (en) * 1969-11-10 1971-11-30 Searle & Co Adamantanecarboxamidoalkanoic acid amides
US3852339A (en) * 1970-06-15 1974-12-03 Squibb & Sons Inc Aminoalkoxyphenylurea derivatives
US3879400A (en) * 1973-11-16 1975-04-22 Upjohn Co 1-Lower alkyl-(1-adamantylmethyl)piperidines and process for their preparation
JPS5346950A (en) * 1976-10-12 1978-04-27 Kao Corp (54)1-acetylaminotricyclo(4,3,1,12,5)undecane and its preparation
US4351847A (en) * 1981-06-26 1982-09-28 Pennwalt Corporation Antiviral alpha, alpha-dialkyl adamantylethylamines
US4551552A (en) * 1984-05-23 1985-11-05 E. I. Du Pont De Nemours And Company Process for preparing rimantadine
US4751245A (en) * 1986-06-25 1988-06-14 E. R. Squibb & Sons, Inc. Antifungal derivatives of N-(6,6-dimethyl-2-hepten-4-ynyl)-1-naphthalenemethanamine and method of using same
US5576355A (en) * 1993-06-04 1996-11-19 Mobil Oil Corp. Diamondoid derivatives for pharmaceutical use
US5684024A (en) * 1996-01-25 1997-11-04 Viropharma Incorporated Pyrazole dimers compositions and methods for treating influenza
US5821243A (en) * 1996-07-22 1998-10-13 Viropharma Incorporated Compounds compositions and methods for treating influenza
PT870757E (pt) * 1997-04-10 2002-09-30 Pfizer Derivados de adamantano substituidos por fluoro
GB0013737D0 (en) 2000-06-07 2000-07-26 Astrazeneca Ab Novel compounds
WO2003004461A1 (en) * 2001-07-02 2003-01-16 Schering Corporation Drugs for treating viral infections
SE0103836D0 (sv) * 2001-11-16 2001-11-16 Astrazeneca Ab Novel compounds
KR20040088519A (ko) 2002-02-22 2004-10-16 뉴 리버 파마슈티칼스, 인크. 활성 제제 전달 시스템 및 활성 제제의 보호 및 투여 방법
WO2004056744A1 (en) * 2002-12-23 2004-07-08 Janssen Pharmaceutica N.V. Adamantyl acetamides as hydroxysteroid dehydrogenase inhibitors
SE0300480D0 (sv) 2003-02-21 2003-02-21 Astrazeneca Ab Novel compounds
GB0312609D0 (en) 2003-06-02 2003-07-09 Astrazeneca Ab Novel compounds
MX2007015863A (es) * 2005-06-17 2008-04-02 Apogee Biotechnology Corp Inhibidores de esfingosina cinasa.
AR057623A1 (es) 2005-11-28 2007-12-05 Omega Bio Pharma H K Ltd Materiales y metodos para el tratamiento de las infecciones virales
CN101679350B (zh) 2007-03-22 2014-03-12 阿斯利康(瑞典)有限公司 用于治疗炎性疾病的喹啉衍生物
RU2348611C1 (ru) * 2007-05-02 2009-03-10 Государственное образовательное учреждение высшего профессионального образования Волгоградский государственный технический университет (ВолгГТУ) Способ получения n,n-диалкилзамещенных амидов адамантилалкилкарбоновых кислот
RU2344122C1 (ru) * 2007-07-09 2009-01-20 Государственное образовательное учреждение высшего профессионального образования Волгоградский государственный технический университет (ВолгГТУ) Способ получения диалкиламидов 3-бром-1-адамантилалканкарбоновых кислот
US8106073B2 (en) 2007-11-30 2012-01-31 Astrazeneca Ab Quinoline derivatives 057
EP2912047B1 (en) 2012-10-29 2016-08-24 Cipla Limited Antiviral phosphonate analogues and process for preparation thereof
EP3080086B1 (en) * 2013-12-09 2017-07-05 Unilever PLC, a company registered in England and Wales under company no. 41424 of Process of making adamantanamides
EP3383429B1 (en) 2015-11-30 2020-10-14 INSERM - Institut National de la Santé et de la Recherche Médicale Nmdar antagonists for the treatment of tumor angiogenesis
US11548893B2 (en) 2017-07-15 2023-01-10 Arisan Therapeutics Inc. Enantiomerically pure adamantane carboxamides for the treatment of filovirus infection

Also Published As

Publication number Publication date
DE1793207A1 (de) 1972-03-30
CH476673A (de) 1969-08-15
IL21753A (en) 1968-01-25
SE330693B (enrdf_load_html_response) 1970-11-30
FR1572956A (enrdf_load_html_response) 1969-07-04
NL6408505A (enrdf_load_html_response) 1965-01-25
GB1069563A (en) 1967-05-17
SE321924B (enrdf_load_html_response) 1970-03-23
NL7102097A (enrdf_load_html_response) 1971-05-25
ES302369A1 (es) 1965-03-16
US3352912A (en) 1967-11-14
DE1792295B1 (de) 1971-05-27
DK114769B (da) 1969-08-04
FI42548B (enrdf_load_html_response) 1970-06-01
BE650919A (enrdf_load_html_response) 1964-11-16
DE1468769B1 (de) 1972-06-29
FI42322B (enrdf_load_html_response) 1970-03-31
AT279581B (de) 1970-03-10
DE1793208A1 (de) 1972-04-06
DK114199B (da) 1969-06-09
FI42211B (enrdf_load_html_response) 1970-03-02
SE320363B (enrdf_load_html_response) 1970-02-09
BR6460975D0 (pt) 1973-08-09
DK112027B (da) 1968-11-04

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