CH465617A - Verfahren zur Herstellung von (3-Amino-5,6-disubstituierten-pyrazinoyl)-guanidin-Verbindungen - Google Patents

Verfahren zur Herstellung von (3-Amino-5,6-disubstituierten-pyrazinoyl)-guanidin-Verbindungen

Info

Publication number
CH465617A
CH465617A CH1329763A CH1329763A CH465617A CH 465617 A CH465617 A CH 465617A CH 1329763 A CH1329763 A CH 1329763A CH 1329763 A CH1329763 A CH 1329763A CH 465617 A CH465617 A CH 465617A
Authority
CH
Switzerland
Prior art keywords
pyrazinoyl
disubstituted
amino
preparation
guanidine compounds
Prior art date
Application number
CH1329763A
Other languages
English (en)
Inventor
Jethro Jr Cragoe Edward
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Priority to CH1806267A priority Critical patent/CH481116A/de
Publication of CH465617A publication Critical patent/CH465617A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CH1329763A 1962-10-30 1963-10-29 Verfahren zur Herstellung von (3-Amino-5,6-disubstituierten-pyrazinoyl)-guanidin-Verbindungen CH465617A (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CH1806267A CH481116A (de) 1962-10-30 1963-10-29 Verfahren zur Herstellung von 3-Amino-pyrazinoaten oder -pyrazinoylguanidinen

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23423062A 1962-10-30 1962-10-30
US313315A US3313813A (en) 1962-10-30 1963-10-07 (3-amino-5, 6-disubstituted-pyrazinoyl) guanidines

Publications (1)

Publication Number Publication Date
CH465617A true CH465617A (de) 1968-11-30

Family

ID=26927694

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1329763A CH465617A (de) 1962-10-30 1963-10-29 Verfahren zur Herstellung von (3-Amino-5,6-disubstituierten-pyrazinoyl)-guanidin-Verbindungen

Country Status (13)

Country Link
US (1) US3313813A (de)
BE (1) BE639386A (de)
BR (1) BR6354164D0 (de)
CH (1) CH465617A (de)
CY (1) CY440A (de)
DE (2) DE1795438C2 (de)
DK (4) DK114978B (de)
FI (1) FI47102C (de)
FR (1) FR1563612A (de)
GB (1) GB1066855A (de)
MY (1) MY6900026A (de)
NL (2) NL142413B (de)
SE (1) SE321230B (de)

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Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL299929A (de) * 1962-10-30

Also Published As

Publication number Publication date
DE1795438B1 (de) 1973-09-06
NL142413B (nl) 1974-06-17
DK116943B (da) 1970-03-02
DE1795438C2 (de) 1974-04-11
DK114978B (da) 1969-08-25
US3313813A (en) 1967-04-11
CY440A (en) 1968-05-18
BE639386A (de)
MY6900026A (en) 1969-12-31
SE321230B (de) 1970-03-02
DK114557B (da) 1969-07-14
DE1470053A1 (de) 1969-06-26
DK115403B (da) 1969-10-06
FI47102C (fi) 1973-09-10
FR1563612A (de) 1969-04-18
BR6354164D0 (pt) 1973-09-18
GB1066855A (en) 1967-04-26
FI47102B (de) 1973-05-31
NL299931A (de)

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