CH463020A - Verfahren zur Herstellung eines neuen Antibioticums (No. 467) - Google Patents

Verfahren zur Herstellung eines neuen Antibioticums (No. 467)

Info

Publication number
CH463020A
CH463020A CH380165A CH380165A CH463020A CH 463020 A CH463020 A CH 463020A CH 380165 A CH380165 A CH 380165A CH 380165 A CH380165 A CH 380165A CH 463020 A CH463020 A CH 463020A
Authority
CH
Switzerland
Prior art keywords
production
new antibiotic
antibiotic
new
Prior art date
Application number
CH380165A
Other languages
English (en)
Inventor
M Luedemann George
J Weinstein Marvin
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of CH463020A publication Critical patent/CH463020A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C07H15/236Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
    • C12P17/189Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms containing the rifamycin nucleus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/46Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
    • C12P19/48Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being substituted by two or more nitrogen atoms, e.g. destomycin, neamin
    • C12P19/485Having two saccharide radicals bound through only oxygen to non-adjacent ring carbons of the cyclohexyl radical, e.g. gentamycin, kanamycin, sisomycin, verdamycin, mutamycin, tobramycin, nebramycin, antibiotics 66-40B, 66-40D, XK-62-2, 66-40, G-418, G-52
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/29Micromonospora
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/863Mycobacterium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Sheets, Magazines, And Separation Thereof (AREA)
CH380165A 1962-04-02 1965-03-17 Verfahren zur Herstellung eines neuen Antibioticums (No. 467) CH463020A (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US18448462A 1962-04-02 1962-04-02
US21115462A 1962-07-16 1962-07-16
US21180662A 1962-07-23 1962-07-23
US35416864A 1964-03-23 1964-03-23
US76250468A 1968-09-25 1968-09-25
US76912268A 1968-10-21 1968-10-21

Publications (1)

Publication Number Publication Date
CH463020A true CH463020A (de) 1968-09-30

Family

ID=27558749

Family Applications (3)

Application Number Title Priority Date Filing Date
CH1604266A CH435560A (de) 1962-04-02 1962-11-07 Verfahren zur Herstellung neuer Antibiotica
CH1604366A CH435561A (de) 1962-04-02 1962-11-07 Verfahren zur Herstellung neuer Antibiotica
CH380165A CH463020A (de) 1962-04-02 1965-03-17 Verfahren zur Herstellung eines neuen Antibioticums (No. 467)

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CH1604266A CH435560A (de) 1962-04-02 1962-11-07 Verfahren zur Herstellung neuer Antibiotica
CH1604366A CH435561A (de) 1962-04-02 1962-11-07 Verfahren zur Herstellung neuer Antibiotica

Country Status (15)

Country Link
US (2) US3499078A (de)
JP (2) JPS5130158B1 (de)
BE (1) BE661459A (de)
BR (1) BR6568037D0 (de)
CH (3) CH435560A (de)
DE (1) DE1271896B (de)
DK (3) DK113352B (de)
FI (3) FI43420B (de)
FR (2) FR1522202A (de)
GB (3) GB1021402A (de)
IL (1) IL22998A (de)
MY (1) MY7100131A (de)
NL (1) NL6503263A (de)
NO (1) NO120933B (de)
SE (1) SE322191B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3915956A (en) * 1973-07-09 1975-10-28 Schering Corp Reduction products of everninomicins and methods for their manufacture
US4006225A (en) * 1973-10-31 1977-02-01 Schering Corporation Method of using reduction products of everninomicins as antibacterial agents and pharmaceutical compositions useful therefor
US3901973A (en) * 1973-11-05 1975-08-26 Schering Corp Antibiotic everninomicin 1
US3993748A (en) * 1975-01-20 1976-11-23 The Upjohn Company Antibiotic U-47,929 and its preparation
US3991183A (en) * 1975-05-01 1976-11-09 Pfizer Inc. Antibiotic produced by a species of micromonospora
JPS5371652U (de) * 1976-11-17 1978-06-15
JPS5492268U (de) * 1977-12-13 1979-06-29
JPS54138501A (en) * 1978-04-20 1979-10-27 Kyowa Hakko Kogyo Co Ltd Antibiotic dc-11 and preparation thereof
US4205068A (en) * 1978-05-18 1980-05-27 E. R. Squibb & Sons, Inc. β-Lactamase inhibitor EM4615
US4331659A (en) * 1980-09-10 1982-05-25 The Upjohn Company Antibiotic U-62,162 and process of making
US4692333A (en) * 1982-08-26 1987-09-08 Gruppo Lepetit S.P.A. Antimicrobial and antitumor antibiotic M 9026 and its pure individual factors 1, 2, and 3 and microbial process for production thereof
DE3871970D1 (de) * 1987-01-29 1992-07-23 Peter Schmidt Transportvorrichtung fuer sportausruestungen.
AU678344B2 (en) * 1991-10-16 1997-05-29 Schering Corporation Lipophilic oligosaccharide antibiotic salt compositions
US20030113715A1 (en) * 2000-01-21 2003-06-19 Daniel Santi Method for cloning polyketide synthase genes
US7257562B2 (en) * 2000-10-13 2007-08-14 Thallion Pharmaceuticals Inc. High throughput method for discovery of gene clusters
SG185790A1 (en) 2010-06-30 2013-01-30 Kla Tencor Corp Method and arrangement for positioning electronic devices into compartments of an input medium and output medium
AU2016366529A1 (en) 2015-12-09 2018-06-07 Vanderbilt University Biosynthesis of everninomicin analogs in Micromonospora carbonacea var aurantiaca

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1021401A (en) * 1961-11-14 1966-03-02 Scherico Ltd Novel antibiotics and processes for their manufacture

Also Published As

Publication number Publication date
US3499078A (en) 1970-03-03
GB1083662A (en) 1967-09-20
DK114753B (da) 1969-08-04
NL6503263A (de) 1965-09-24
DE1271896B (de) 1968-07-04
FI43422B (de) 1970-12-31
DK116862B (da) 1970-02-23
FR128F (de)
BR6568037D0 (pt) 1973-08-07
CH435560A (de) 1967-05-15
IL22998A (en) 1969-01-29
GB1021403A (en) 1966-03-02
JPS5130158B1 (de) 1976-08-30
NO120933B (de) 1970-12-28
FI43421B (de) 1970-12-31
DK113352B (da) 1969-03-17
BE661459A (de) 1965-09-22
MY7100131A (en) 1971-12-31
SE322191B (de) 1970-04-06
FR1522202A (fr) 1968-04-26
GB1021402A (en) 1966-03-02
US3511909A (en) 1970-05-12
CH435561A (de) 1967-05-15
JPS5130157B1 (de) 1976-08-30
FI43420B (de) 1970-12-31

Similar Documents

Publication Publication Date Title
CH446367A (de) Verfahren zur Herstellung von neuen Lumilysergolderivaten
CH463020A (de) Verfahren zur Herstellung eines neuen Antibioticums (No. 467)
AT253469B (de) Verfahren zur Herstellung eines neuen Katalysators
AT269356B (de) Verfahren zur Herstellung eines neuen Antibiotikums
AT270067B (de) Verfahren zur Herstellung eines neuen Antibiotikums
CH469089A (de) Verfahren zur Herstellung eines neuen Antibiotikums
AT243239B (de) Verfahren zur Herstellung von Cyclododekatrienen-(1, 5, 9)
AT267063B (de) Verfahren zur Herstellung eines neuen Antibioticums
CH471782A (de) Verfahren zur Herstellung eines neuen, substituierten 2,3-Pyridindiols
CH415658A (de) Verfahren zur Herstellung von neuen Urethanen
AT300195B (de) Verfahren zur Herstellung eines neuen Antibioticums
CH476102A (de) Verfahren zur Herstellung eines neuen Antibiotikums
AT257040B (de) Verfahren zur Herstellung eines neuen Antibiotikums
AT299448B (de) Verfahren zur Herstellung eines neuen Antibiotikums
AT292194B (de) Verfahren zur Herstellung eines neuen Antibioticums
AT257059B (de) Verfahren zur Herstellung von neuen 6, 16α-Dialkyl-17α-hydroxy-progesteronen
AT264008B (de) Verfahren zur Herstellung eines neuen Antibioticums
CH410286A (de) Verfahren zur Herstellung eines neuen Antibiotikums
AT258482B (de) Verfahren zur Herstellung neuer 6-Methyl- und 1,6-Dimethyl-8-amino-methyl-ergolin-I-derivate
CH459468A (de) Verfahren zur Herstellung eines neuen Antibioticums
AT255028B (de) Verfahren zur Herstellung eines neuen Antibiotikums
CH461707A (de) Verfahren zur Herstellung eines neuen Antibiotikums
CH420197A (de) Verfahren zur Herstellung eines neuen mitosehemmenden Präparates
CH452512A (de) Verfahren zur Herstellung von neuen 9 B,19-Cyclosteroiden
CH517176A (de) Verfahren zur Herstellung eines neuen antibiotischen Wirkstoffs