CH457464A - Verfahren zur Herstellung von Benzodiazepin-Derivaten - Google Patents

Verfahren zur Herstellung von Benzodiazepin-Derivaten

Info

Publication number
CH457464A
CH457464A CH1765866A CH1765866A CH457464A CH 457464 A CH457464 A CH 457464A CH 1765866 A CH1765866 A CH 1765866A CH 1765866 A CH1765866 A CH 1765866A CH 457464 A CH457464 A CH 457464A
Authority
CH
Switzerland
Prior art keywords
voltage
coil
diodes
temperature compensation
volts
Prior art date
Application number
CH1765866A
Other languages
German (de)
English (en)
Inventor
Reeder Earl
Stempel Arthur
Henryk Sternbach Leo
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US240750A external-priority patent/US3340253A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CH457464A publication Critical patent/CH457464A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/20Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/26Preparation from compounds already containing the benzodiazepine skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Inductance-Capacitance Distribution Constants And Capacitance-Resistance Oscillators (AREA)
CH1765866A 1962-03-09 1963-02-21 Verfahren zur Herstellung von Benzodiazepin-Derivaten CH457464A (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17855162A 1962-03-09 1962-03-09
US240750A US3340253A (en) 1962-11-28 1962-11-28 Preparation of certain benzodiazepine compounds

Publications (1)

Publication Number Publication Date
CH457464A true CH457464A (de) 1968-06-15

Family

ID=26874429

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1765866A CH457464A (de) 1962-03-09 1963-02-21 Verfahren zur Herstellung von Benzodiazepin-Derivaten
CH222063A CH442326A (de) 1962-03-09 1963-02-21 Verfahren zur Herstellung von Benzodiazepin-Derivaten

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH222063A CH442326A (de) 1962-03-09 1963-02-21 Verfahren zur Herstellung von Benzodiazepin-Derivaten

Country Status (9)

Country Link
BE (1) BE629227A (show.php)
CA (1) CA976547A (show.php)
CH (2) CH457464A (show.php)
DE (4) DE1545955A1 (show.php)
DK (1) DK127507B (show.php)
ES (1) ES285854A1 (show.php)
GB (2) GB1013900A (show.php)
NL (3) NL7010711A (show.php)
SE (2) SE328583B (show.php)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES405260A1 (es) * 1972-07-28 1975-07-01 Stabilimenti Chim Farmac Riuni Procedimiento para la preparacion de 3-hidroxi-5-aril-7- sustituidos-1, 3-dihidro-2h-1, 4-benzodiacepin-2-onas.
NL173269C (nl) * 1974-04-30 1984-01-02 Ferrer Int Werkwijze voor de bereiding van een geneesmiddel met als werkzaam bestanddeel een 1,4-benzodiazepinederivaat, alsmede werkwijze voor de bereiding van het 1,4-benzodiazepinederivaat.
DE3413592C2 (de) * 1984-04-11 1986-06-05 Dolorgiet GmbH & Co KG, 5205 St Augustin Arzneimittel enthaltend 5-(2-Fluorphenyl)-1,3-dihydro-3-hydroxy-1-methyl-7-nitro-2H-1,4-benzodiazepin-2-on
ES8609278A1 (es) * 1984-06-26 1986-09-01 Merck & Co Inc Un procedimiento para la preparacion de analogos de benzodiazepina.

Also Published As

Publication number Publication date
SE328583B (show.php) 1970-09-21
DE1545956A1 (de) 1969-11-20
DE1545957A1 (de) 1969-12-11
CA976547A (en) 1975-10-21
BE629227A (fr) 1963-10-21
DK127507B (da) 1973-11-19
GB1013900A (en) 1965-12-22
ES285854A1 (es) 1963-08-16
NL7010711A (show.php) 1970-10-26
DE1545955A1 (de) 1969-11-20
GB1013229A (en) 1965-12-15
NL289735A (show.php)
CH442326A (de) 1967-08-31
NL7010712A (show.php) 1970-10-26
DE1445873A1 (de) 1969-04-10
SE361174B (show.php) 1973-10-22

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