CH442286A - Procédé de préparation de nouveaux pyrazolostéroïdes - Google Patents

Procédé de préparation de nouveaux pyrazolostéroïdes

Info

Publication number
CH442286A
CH442286A CH1007165A CH1007165A CH442286A CH 442286 A CH442286 A CH 442286A CH 1007165 A CH1007165 A CH 1007165A CH 1007165 A CH1007165 A CH 1007165A CH 442286 A CH442286 A CH 442286A
Authority
CH
Switzerland
Prior art keywords
estra
oxo
methoxy
hydroxy
dihydropyrazole
Prior art date
Application number
CH1007165A
Other languages
English (en)
French (fr)
Inventor
Bertin Daniel
Nedelec Lucien
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH627763A external-priority patent/CH442294A/de
Priority claimed from FR982628A external-priority patent/FR1514079A/fr
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of CH442286A publication Critical patent/CH442286A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only
    • C07J71/0052—Nitrogen only at position 16(17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
CH1007165A 1963-05-17 1965-07-19 Procédé de préparation de nouveaux pyrazolostéroïdes CH442286A (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CH627763A CH442294A (de) 1963-05-17 1963-05-17 Verfahren zur Herstellung neuer 7a-Methyl-androstene
CH627863A CH429715A (de) 1963-05-17 1963-05-17 Verfahren zur Herstellung neuer 4-Halogen-androstene
CH299164 1964-03-09
CH299264 1964-03-09
FR982628A FR1514079A (fr) 1964-07-22 1964-07-22 Nouveaux pyrazolo stéroïdes et procédé de préparation

Publications (1)

Publication Number Publication Date
CH442286A true CH442286A (fr) 1967-08-31

Family

ID=27509107

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1007165A CH442286A (fr) 1963-05-17 1965-07-19 Procédé de préparation de nouveaux pyrazolostéroïdes

Country Status (2)

Country Link
CH (1) CH442286A (enrdf_load_stackoverflow)
NL (1) NL6405462A (enrdf_load_stackoverflow)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0573977A3 (en) * 1992-06-11 1996-01-31 Kureha Chemical Ind Co Ltd Novel estradiol derivative-chlorambucil conjugate, process for preparing the same, and pharmaceutical composition

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0573977A3 (en) * 1992-06-11 1996-01-31 Kureha Chemical Ind Co Ltd Novel estradiol derivative-chlorambucil conjugate, process for preparing the same, and pharmaceutical composition
US5576309A (en) * 1992-06-11 1996-11-19 Kureha Chemical Industry Co., Ltd. Estradiol derivative-chlorambucil conjugate, process for preparing the same, and pharmaceutical composition

Also Published As

Publication number Publication date
NL6405462A (enrdf_load_stackoverflow) 1964-11-18

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