CH401987A - Procédé d'extraction et de purification de l'acide glutamique - Google Patents
Procédé d'extraction et de purification de l'acide glutamiqueInfo
- Publication number
- CH401987A CH401987A CH627261A CH627261A CH401987A CH 401987 A CH401987 A CH 401987A CH 627261 A CH627261 A CH 627261A CH 627261 A CH627261 A CH 627261A CH 401987 A CH401987 A CH 401987A
- Authority
- CH
- Switzerland
- Prior art keywords
- glutamic acid
- acid
- exchange resin
- cation exchange
- acidic cation
- Prior art date
Links
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 title claims description 38
- 235000013922 glutamic acid Nutrition 0.000 title claims description 37
- 239000004220 glutamic acid Substances 0.000 title claims description 37
- 238000000034 method Methods 0.000 title claims description 12
- 238000000605 extraction Methods 0.000 title claims description 3
- 238000000746 purification Methods 0.000 title claims description 3
- 230000002378 acidificating effect Effects 0.000 claims description 20
- 239000003729 cation exchange resin Substances 0.000 claims description 15
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 claims description 14
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 9
- 239000002253 acid Substances 0.000 claims description 8
- 238000001179 sorption measurement Methods 0.000 claims description 7
- 239000003513 alkali Substances 0.000 claims description 5
- 239000012535 impurity Substances 0.000 claims description 4
- 125000002091 cationic group Chemical group 0.000 claims description 3
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 claims 1
- 239000012670 alkaline solution Substances 0.000 claims 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-N ammonia Natural products N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 150000001768 cations Chemical class 0.000 description 11
- 238000000855 fermentation Methods 0.000 description 10
- 230000004151 fermentation Effects 0.000 description 9
- 239000011347 resin Substances 0.000 description 9
- 229920005989 resin Polymers 0.000 description 9
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 8
- 238000003795 desorption Methods 0.000 description 6
- 239000000047 product Substances 0.000 description 5
- 229920002125 Sokalan® Polymers 0.000 description 4
- 150000001450 anions Chemical class 0.000 description 4
- 150000002500 ions Chemical class 0.000 description 4
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 3
- 229920001429 chelating resin Polymers 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 235000011121 sodium hydroxide Nutrition 0.000 description 3
- MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 229940023913 cation exchange resins Drugs 0.000 description 2
- 239000003518 caustics Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 238000002425 crystallisation Methods 0.000 description 2
- 230000008025 crystallization Effects 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 239000003792 electrolyte Substances 0.000 description 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 2
- 239000002244 precipitate Substances 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- DPEYHNFHDIXMNV-UHFFFAOYSA-N (9-amino-3-bicyclo[3.3.1]nonanyl)-(4-benzyl-5-methyl-1,4-diazepan-1-yl)methanone dihydrochloride Chemical compound Cl.Cl.CC1CCN(CCN1Cc1ccccc1)C(=O)C1CC2CCCC(C1)C2N DPEYHNFHDIXMNV-UHFFFAOYSA-N 0.000 description 1
- 108010054404 Adenylyl-sulfate kinase Proteins 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 description 1
- 102100039024 Sphingosine kinase 1 Human genes 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- -1 amino acid ion Chemical class 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000009950 felting Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 239000003456 ion exchange resin Substances 0.000 description 1
- 229920003303 ion-exchange polymer Polymers 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000012452 mother liquor Substances 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 235000008935 nutritious Nutrition 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 238000012799 strong cation exchange Methods 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N urea group Chemical group NC(=O)N XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/14—Glutamic acid; Glutamine
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/04—Processes using organic exchangers
- B01J39/05—Processes using organic exchangers in the strongly acidic form
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2566960 | 1960-05-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH401987A true CH401987A (fr) | 1965-11-15 |
Family
ID=12172175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH627261A CH401987A (fr) | 1960-05-30 | 1961-05-30 | Procédé d'extraction et de purification de l'acide glutamique |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US3173949A (en:Method) |
| BE (1) | BE604404A (en:Method) |
| CH (1) | CH401987A (en:Method) |
| DE (1) | DE1417603A1 (en:Method) |
| GB (1) | GB947797A (en:Method) |
| NL (2) | NL123588C (en:Method) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997027170A1 (en) * | 1996-01-22 | 1997-07-31 | Amylum N.V. | A process for producing glutamic acid |
| WO1998003468A1 (en) * | 1996-07-18 | 1998-01-29 | Amylum N.V. | A process for the production of crystalline aspartic acid |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3331828A (en) * | 1964-09-30 | 1967-07-18 | Merck & Co Inc | Isolation of gamma-l-glutamyl dipeptides from glutamic acid fermentation broths by ion exchange |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1973574A (en) * | 1931-04-29 | 1934-09-11 | Larrowe Suzuki Company | Process for manufacturing and recovering glutamic acid |
| US2738353A (en) * | 1951-11-24 | 1956-03-13 | Int Minerals & Chem Corp | Purification and recovery of pyrrolidone carboxylic acid |
| US3015655A (en) * | 1955-07-18 | 1962-01-02 | John B Stark | Separation of nitrogenous organic compounds |
-
0
- NL NL265337D patent/NL265337A/xx unknown
- NL NL123588D patent/NL123588C/xx active
-
1961
- 1961-05-29 GB GB19375/61A patent/GB947797A/en not_active Expired
- 1961-05-29 US US113078A patent/US3173949A/en not_active Expired - Lifetime
- 1961-05-30 BE BE604404A patent/BE604404A/fr unknown
- 1961-05-30 DE DE19611417603 patent/DE1417603A1/de active Pending
- 1961-05-30 CH CH627261A patent/CH401987A/fr unknown
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997027170A1 (en) * | 1996-01-22 | 1997-07-31 | Amylum N.V. | A process for producing glutamic acid |
| US6147259A (en) * | 1996-01-22 | 2000-11-14 | Amylum N.V. | Process for producing glutamic acid |
| CN1125037C (zh) * | 1996-01-22 | 2003-10-22 | 阿米卢姆公司 | 生产谷氨酸的方法 |
| WO1998003468A1 (en) * | 1996-07-18 | 1998-01-29 | Amylum N.V. | A process for the production of crystalline aspartic acid |
Also Published As
| Publication number | Publication date |
|---|---|
| BE604404A (fr) | 1961-09-18 |
| GB947797A (en) | 1964-01-29 |
| NL265337A (en:Method) | |
| US3173949A (en) | 1965-03-16 |
| NL123588C (en:Method) | |
| DE1417603A1 (de) | 1968-10-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4075406A (en) | Process for making xylose | |
| CN100381452C (zh) | 由甘蔗渣生产结晶木糖的方法、所得结晶木糖、由所述木糖生产木糖醇的方法及所得木糖醇 | |
| AU594316B2 (en) | Process for the preparation of crystalline maltitol | |
| JPS60199390A (ja) | クエン酸の取得法 | |
| JP2016520093A (ja) | 前処理ありのフェルラ酸の最適化抽出方法 | |
| EP0633240B1 (en) | Recovery of citric acid from impure process streams by addition of strong acids and salts thereof | |
| FR2538394A1 (fr) | Procede pour la purification de glycosides anthracyclinoniques par adsorption selective sur des resines | |
| US2375165A (en) | Recovery of nitrogenous products from organic wastes | |
| JP2000511199A (ja) | キシリトールの製造方法 | |
| US4584399A (en) | Purification of L-phenylalanine | |
| JPH026443A (ja) | Ｌ―リジンのイオン交換回収 | |
| JPH02275835A (ja) | クエン酸含有液からのクエン酸の回収方法 | |
| CH401987A (fr) | Procédé d'extraction et de purification de l'acide glutamique | |
| JPS5929240B2 (ja) | キシロ−スの製造方法 | |
| US2528047A (en) | Recovery of glutamic compounds from glutamine contained in an impure solution thereof | |
| CN113956304B (zh) | 一种n-乙酰神经氨酸的制备方法 | |
| US4182634A (en) | Process for purifying maltose solution | |
| JPH01244000A (ja) | 甜菜糖液を処理する方法 | |
| JPS604168A (ja) | トリプトフアンの晶析法 | |
| JP3096503B2 (ja) | エリスリトール結晶の製造方法 | |
| CN104761432B (zh) | 一种利用冬笋壳制备木糖醇的方法 | |
| JPH06107611A (ja) | ベタインの製造方法 | |
| CN105254518B (zh) | Dl‑赖氨酸的脱色纯化方法 | |
| JPS61234789A (ja) | Ｌ―トリプトファンよりインドールの分離回収方法 | |
| JPH0755957B2 (ja) | キシロ−スおよびキシロオリゴ糖の製造方法 |