CH388334A - Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten - Google Patents

Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten

Info

Publication number
CH388334A
CH388334A CH462964A CH462964A CH388334A CH 388334 A CH388334 A CH 388334A CH 462964 A CH462964 A CH 462964A CH 462964 A CH462964 A CH 462964A CH 388334 A CH388334 A CH 388334A
Authority
CH
Switzerland
Prior art keywords
preparation
basic substituted
diphenylalkane
derivatives
diphenylalkane derivatives
Prior art date
Application number
CH462964A
Other languages
German (de)
English (en)
Inventor
Ehrhart Gustav Dr Prof
Ott Heinrich
Ernst Dr Lindner
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of CH388334A publication Critical patent/CH388334A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CH462964A 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten CH388334A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEF25702A DE1111642B (de) 1958-05-07 1958-05-07 Verfahren zur Herstellung von basisch substituierten Diphenylmethan-Derivaten mit Herz- und Kreislaufwirksamkeit

Publications (1)

Publication Number Publication Date
CH388334A true CH388334A (de) 1965-02-28

Family

ID=7091732

Family Applications (8)

Application Number Title Priority Date Filing Date
CH462964A CH388334A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH463064A CH396931A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH462764A CH388332A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH463164A CH388328A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH463264A CH388329A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH708765A CH397710A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH462864A CH388333A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH7291559A CH385878A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten

Family Applications After (7)

Application Number Title Priority Date Filing Date
CH463064A CH396931A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH462764A CH388332A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH463164A CH388328A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH463264A CH388329A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH708765A CH397710A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH462864A CH388333A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH7291559A CH385878A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten

Country Status (10)

Country Link
US (1) US3152173A (OSRAM)
BE (1) BE578515A (OSRAM)
CH (8) CH388334A (OSRAM)
CY (1) CY277A (OSRAM)
DE (1) DE1111642B (OSRAM)
FR (1) FR553M (OSRAM)
GB (1) GB916644A (OSRAM)
MY (1) MY6400049A (OSRAM)
NL (2) NL238796A (OSRAM)
OA (1) OA01363A (OSRAM)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3262977A (en) * 1962-03-10 1966-07-26 Chinoin Gyogyszer Es Vegyeszet N-aralkyl-1, 1-diphenyl-propylamine derivatives
NL296693A (OSRAM) * 1962-08-16
DK111894A (OSRAM) 1962-11-15
FR95908E (fr) * 1963-11-09 1972-01-31 Degussa Procédé de préparation de nouvelles aminocétones et des alcools secondaires correspondants.
DE1231704B (de) 1963-12-19 1967-01-05 Josef Klosa Dipl Chem Dr Rer N Verfahren zur Herstellung neuer Diaryl-alkylaminoverbindungen mit heterocyclischen Ringen
US3457354A (en) * 1965-09-21 1969-07-22 Merck & Co Inc Treatment of hypertension with 2-hydroxy (or amino) - 4,5 - dihydroxyphenethylamine derivatives
US3895057A (en) * 1967-10-13 1975-07-15 Dainippon Pharmaceutical Co Aminoalkanols and their pharmaceutically acceptable acid-addition salts, and production thereof
US4329367A (en) * 1974-08-05 1982-05-11 Ciba-Geigy Corporation 1-(Aralkoxyphenyl)-2-(bis-arylalkylamino)-alkanes
DE2902172C2 (de) * 1979-01-20 1984-05-10 UOP Inc., 60016 Des Plaines, Ill. Verfahren zur Herstellung eines N,N'-Dialkylphenylendiamins
DE3278278D1 (en) * 1982-04-23 1988-05-05 Caola Kozmetikai Novel cosmetic compositions containing prenylamine and a process for their preparation
EP0198412B1 (de) * 1985-04-16 1989-03-22 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Phenäthanolaminderivate
US6982251B2 (en) * 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
CA2434430A1 (en) * 2001-01-26 2002-08-01 Harry R. Davis The use of substituted azetidinone compounds for the treatment of sitosterolemia
US7071181B2 (en) * 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
EP2039357A2 (en) * 2001-01-26 2009-03-25 Schering Corporation Combinations of sterol absorption inhibitor(s) with cardiovascular agent(s) for the treatment of vascular conditions
HUP0303915A3 (en) * 2001-01-26 2012-12-28 Merck Sharp & Dohme Combinations of peroxisome proliferator-activated receptor (ppar) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications
ATE369851T1 (de) * 2001-01-26 2007-09-15 Schering Corp Kombinationen von gallensäuresequestriermitteln und hemmern der sterolabsorption zur behandlung von kardiovaskulären indikationen
CA2434488A1 (en) * 2001-01-26 2002-08-01 Harry R. Davis Combinations of nicotinic acid and derivatives thereof and sterol absorption inhibitor(s) and treatments for vascular indications
DK1353694T3 (da) * 2001-01-26 2008-03-25 Schering Corp Kombinationer af ezetimibe med aspirin til behandling af vaskulære tilstande
CA2447884A1 (en) * 2001-05-25 2002-12-05 Schering Corporation Use of azetidinone substituted derivatives in the treatment of alzheimer's disease
MXPA04002573A (es) * 2001-09-21 2004-06-18 Schering Corp Tratamiento de xantoma con derivados de azetidinona como inhibidores de la absorcion de esterol.
US20030119808A1 (en) * 2001-09-21 2003-06-26 Schering Corporation Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects
US7056906B2 (en) * 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
CN101785772A (zh) * 2001-09-21 2010-07-28 先灵公司 使用甾醇吸收抑制剂治疗或预防脉管炎的方法
US7053080B2 (en) * 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
KR100668539B1 (ko) 2002-08-19 2007-01-16 화이자 프로덕츠 인크. 과증식성 질환에 대한 조합요법
US20040092499A1 (en) * 2002-11-06 2004-05-13 Schering Corporation Methods and therapeutic combinations for the treatment of autoimmune disorders
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
CA2517572C (en) 2003-03-07 2011-12-13 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
ATE406364T1 (de) 2003-03-07 2008-09-15 Schering Corp Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia
CN1756755A (zh) * 2003-03-07 2006-04-05 先灵公司 取代的2-吖丁啶酮化合物、其制剂及其治疗高胆甾醇血症的用途
JP2007510659A (ja) * 2003-11-05 2007-04-26 シェーリング コーポレイション 脂質調節剤および置換アゼチジノンの組み合わせならびに血管状態の処置
MX2007000979A (es) * 2004-07-26 2007-07-11 Cotherix Inc Tratamiento de la hipertension pulmonar por iloprost inhalado con una formulacion microparticulada.
US20060063803A1 (en) * 2004-09-23 2006-03-23 Pfizer Inc 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
ATE551059T1 (de) * 2005-10-26 2012-04-15 Asahi Kasei Pharma Corp Fasudil in kombination mit bosentan zur behandlung von pulmonaler arterieller hypertonie
EP2351569B1 (en) 2005-10-26 2012-08-22 Asahi Kasei Pharma Corporation Fasudil in combination therapies for the treatment of pulmonary arterial hypertension
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
CN101663262B (zh) 2006-12-01 2014-03-26 百时美施贵宝公司 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
JP5546451B2 (ja) 2007-06-04 2014-07-09 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸の障害、炎症、癌および他の障害の処置に有用なグアニル酸シクラーゼのアゴニスト
JP2011522828A (ja) 2008-06-04 2011-08-04 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
JP2011528375A (ja) 2008-07-16 2011-11-17 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
US8883844B2 (en) 2010-09-24 2014-11-11 Nitrogenix Inc. Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
JP2016514670A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
HK1213886A1 (zh) 2013-04-17 2016-07-15 辉瑞大药厂 用於治療心血管疾病的n-哌啶-3-基苯甲酰胺衍生物
CN113388007A (zh) 2013-06-05 2021-09-14 博士医疗爱尔兰有限公司 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
PH12021551686A1 (en) 2019-01-18 2022-05-16 Astrazeneca Ab Pcsk9 inhibitors and methods of use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2601323A (en) * 1949-02-02 1952-06-24 Upjohn Co Process for preparing 4, 4-diphenyl-6-dimethylamino-heptanone-3
US2681934A (en) * 1950-01-06 1954-06-22 Commercial Solvents Corp Substituted diphenylalkylamines
US2797242A (en) * 1953-08-11 1957-06-25 Parke Davis & Co Substituted alpha-benzylphenethylamines and methods for producing the same
US2738347A (en) * 1954-12-13 1956-03-13 Olin Mathieson Penicillin salt of benzhydryl-phenethylamine
US2872374A (en) * 1955-02-02 1959-02-03 Nat Drug Co Muscle-relaxing tranquilizer compositions
US2894033A (en) * 1955-11-15 1959-07-07 Nl Combinatie Chem Ind Antispasmodic 1, 1-diphenyl-3-dialkylaminopropane, and its tertiary and quaternary salts
US2854379A (en) * 1956-06-06 1958-09-30 Miles Lab Tranquilizing composition comprising 2-ethyl-cis-crotonylurea
DE1058063B (de) * 1957-02-08 1959-05-27 Hoechst Ag Verfahren zur Herstellung von analgetisch wirksamen substituierten Phenylaethylaminen

Also Published As

Publication number Publication date
BE578515A (OSRAM)
CH388328A (de) 1965-02-28
CH385878A (de) 1964-12-31
FR553M (OSRAM) 1961-05-29
CH388332A (de) 1965-02-28
OA01363A (fr) 1969-07-04
MY6400049A (en) 1964-12-31
NL238796A (OSRAM)
CH397710A (de) 1965-08-31
CH388333A (de) 1965-02-28
CH388329A (de) 1965-02-28
US3152173A (en) 1964-10-06
CH396931A (de) 1965-08-15
NL108640C (OSRAM)
GB916644A (en) 1963-01-23
DE1111642B (de) 1961-07-27
CY277A (en) 1964-02-12

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