CH388329A - Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten - Google Patents

Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten

Info

Publication number
CH388329A
CH388329A CH463264A CH463264A CH388329A CH 388329 A CH388329 A CH 388329A CH 463264 A CH463264 A CH 463264A CH 463264 A CH463264 A CH 463264A CH 388329 A CH388329 A CH 388329A
Authority
CH
Switzerland
Prior art keywords
preparation
basic substituted
diphenylalkane
derivatives
diphenylalkane derivatives
Prior art date
Application number
CH463264A
Other languages
German (de)
English (en)
Inventor
Ehrhart Gustav Dr Prof
Ott Heinrich
Ernst Dr Lindner
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of CH388329A publication Critical patent/CH388329A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CH463264A 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten CH388329A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEF25702A DE1111642B (de) 1958-05-07 1958-05-07 Verfahren zur Herstellung von basisch substituierten Diphenylmethan-Derivaten mit Herz- und Kreislaufwirksamkeit

Publications (1)

Publication Number Publication Date
CH388329A true CH388329A (de) 1965-02-28

Family

ID=7091732

Family Applications (8)

Application Number Title Priority Date Filing Date
CH462964A CH388334A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH463164A CH388328A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH708765A CH397710A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH462864A CH388333A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH463264A CH388329A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH7291559A CH385878A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH463064A CH396931A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH462764A CH388332A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten

Family Applications Before (4)

Application Number Title Priority Date Filing Date
CH462964A CH388334A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH463164A CH388328A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH708765A CH397710A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH462864A CH388333A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten

Family Applications After (3)

Application Number Title Priority Date Filing Date
CH7291559A CH385878A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH463064A CH396931A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH462764A CH388332A (de) 1958-05-07 1959-05-05 Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten

Country Status (10)

Country Link
US (1) US3152173A (US20060009399A1-20060112-C00020.png)
BE (1) BE578515A (US20060009399A1-20060112-C00020.png)
CH (8) CH388334A (US20060009399A1-20060112-C00020.png)
CY (1) CY277A (US20060009399A1-20060112-C00020.png)
DE (1) DE1111642B (US20060009399A1-20060112-C00020.png)
FR (1) FR553M (US20060009399A1-20060112-C00020.png)
GB (1) GB916644A (US20060009399A1-20060112-C00020.png)
MY (1) MY6400049A (US20060009399A1-20060112-C00020.png)
NL (2) NL108640C (US20060009399A1-20060112-C00020.png)
OA (1) OA01363A (US20060009399A1-20060112-C00020.png)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3262977A (en) * 1962-03-10 1966-07-26 Chinoin Gyogyszer Es Vegyeszet N-aralkyl-1, 1-diphenyl-propylamine derivatives
NL296693A (US20060009399A1-20060112-C00020.png) * 1962-08-16
FR95908E (fr) * 1963-11-09 1972-01-31 Degussa Procédé de préparation de nouvelles aminocétones et des alcools secondaires correspondants.
US3457354A (en) * 1965-09-21 1969-07-22 Merck & Co Inc Treatment of hypertension with 2-hydroxy (or amino) - 4,5 - dihydroxyphenethylamine derivatives
US3895057A (en) * 1967-10-13 1975-07-15 Dainippon Pharmaceutical Co Aminoalkanols and their pharmaceutically acceptable acid-addition salts, and production thereof
US4329367A (en) * 1974-08-05 1982-05-11 Ciba-Geigy Corporation 1-(Aralkoxyphenyl)-2-(bis-arylalkylamino)-alkanes
DE2902172C2 (de) * 1979-01-20 1984-05-10 UOP Inc., 60016 Des Plaines, Ill. Verfahren zur Herstellung eines N,N'-Dialkylphenylendiamins
WO1983003755A1 (en) * 1982-04-23 1983-11-10 Caola Kozmetikai És Háztartäsvegyipari Vállalat Novel cosmetic compositions containing prenylamine and a process for their preparation
DE3662521D1 (de) * 1985-04-16 1989-04-27 Hoffmann La Roche Phenethanol amine derivatives
US6982251B2 (en) * 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
US7071181B2 (en) * 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
ATE381347T1 (de) * 2001-01-26 2008-01-15 Schering Corp Kombinationen von ezetimibe und aspirin zur behandlung von kardiovaskulären erkrankungen
US7417039B2 (en) * 2001-01-26 2008-08-26 Schering Corporation Use of substituted azetidinone compounds for the treatment of sitosterolemia
US20030053981A1 (en) * 2001-01-26 2003-03-20 Schering Corporation Combinations of bile acid sequestrant(s) and sterol absorption inhibitor(s) and treatments for vascular indications
AU2002240050A1 (en) * 2001-01-26 2002-08-06 Schering Corporation Combinations of nicotinic acid and derivatives thereof and sterol absorption inhibitor(s) and treatments for vascular indications
DK1413331T3 (da) * 2001-01-26 2007-12-10 Schering Corp Kombinationer af peroxisomproliferatoraktiveret receptor (PPAR)-aktivatoren fenofibrat og sterolabsorptionsinhibitoren ezetimib til vaskulære indikationer
KR20080077033A (ko) * 2001-01-26 2008-08-20 쉐링 코포레이션 혈관 질환을 치료하기 위한 스테롤 흡수 억제제와 심혈관제제의 조합물
WO2002096415A2 (en) * 2001-05-25 2002-12-05 Schering Corporation Use of azetidinone substituted derivatives in the treatment of alzheimer's disease
MXPA04002573A (es) * 2001-09-21 2004-06-18 Schering Corp Tratamiento de xantoma con derivados de azetidinona como inhibidores de la absorcion de esterol.
US7053080B2 (en) * 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US7056906B2 (en) * 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
US20030119808A1 (en) * 2001-09-21 2003-06-26 Schering Corporation Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects
MXPA04002572A (es) * 2001-09-21 2004-05-31 Schering Corp Metodos para el tratamiento o prevencion de inflamacion vascular usando inhibidores de absorcion de esterol.
CN1681495B (zh) 2002-08-19 2010-05-12 辉瑞产品公司 用于治疗过度增生性疾病的组合物
EP1562582A1 (en) * 2002-11-06 2005-08-17 Schering Corporation Cholesterol absorption inhibitors for the treatment of demyelination
JP4589919B2 (ja) 2003-03-07 2010-12-01 シェーリング コーポレイション 高コレステロール血症の処置のための、置換アゼチジノン化合物、これらの処方物および使用
ATE406364T1 (de) 2003-03-07 2008-09-15 Schering Corp Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia
MXPA05009502A (es) * 2003-03-07 2005-10-18 Schering Corp Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP2007510659A (ja) * 2003-11-05 2007-04-26 シェーリング コーポレイション 脂質調節剤および置換アゼチジノンの組み合わせならびに血管状態の処置
JP2008507585A (ja) * 2004-07-26 2008-03-13 コセリックス インク 微粒子製剤を用いて吸入したイロプロストによる肺高血圧症の治療
US20060063803A1 (en) * 2004-09-23 2006-03-23 Pfizer Inc 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
ATE551059T1 (de) 2005-10-26 2012-04-15 Asahi Kasei Pharma Corp Fasudil in kombination mit bosentan zur behandlung von pulmonaler arterieller hypertonie
EP2351569B1 (en) 2005-10-26 2012-08-22 Asahi Kasei Pharma Corporation Fasudil in combination therapies for the treatment of pulmonary arterial hypertension
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
ES2382009T3 (es) 2006-12-01 2012-06-04 Bristol-Myers Squibb Company Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2170930B3 (en) 2007-06-04 2013-10-02 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
JP2011522828A (ja) 2008-06-04 2011-08-04 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
AU2009270833B2 (en) 2008-07-16 2015-02-19 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
WO2012037665A1 (en) 2010-09-24 2012-03-29 Oral Delivery Technology Ltd. Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions
WO2014151206A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
JP2016516804A (ja) 2013-04-17 2016-06-09 ファイザー・インク 心血管疾患を治療するためのn−ピペリジン−3−イルベンズアミド誘導体
EP3004138B1 (en) 2013-06-05 2024-03-13 Bausch Health Ireland Limited Ultra-pure agonists of guanylate cyclase c, method of making and using same
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
EP3911648A4 (en) 2019-01-18 2022-10-26 Astrazeneca AB PCSK9 INHIBITORS AND METHODS OF USE THEREOF

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2601323A (en) * 1949-02-02 1952-06-24 Upjohn Co Process for preparing 4, 4-diphenyl-6-dimethylamino-heptanone-3
US2681934A (en) * 1950-01-06 1954-06-22 Commercial Solvents Corp Substituted diphenylalkylamines
US2797242A (en) * 1953-08-11 1957-06-25 Parke Davis & Co Substituted alpha-benzylphenethylamines and methods for producing the same
US2738347A (en) * 1954-12-13 1956-03-13 Olin Mathieson Penicillin salt of benzhydryl-phenethylamine
US2872374A (en) * 1955-02-02 1959-02-03 Nat Drug Co Muscle-relaxing tranquilizer compositions
US2894033A (en) * 1955-11-15 1959-07-07 Nl Combinatie Chem Ind Antispasmodic 1, 1-diphenyl-3-dialkylaminopropane, and its tertiary and quaternary salts
US2854379A (en) * 1956-06-06 1958-09-30 Miles Lab Tranquilizing composition comprising 2-ethyl-cis-crotonylurea
DE1058063B (de) * 1957-02-08 1959-05-27 Hoechst Ag Verfahren zur Herstellung von analgetisch wirksamen substituierten Phenylaethylaminen

Also Published As

Publication number Publication date
GB916644A (en) 1963-01-23
MY6400049A (en) 1964-12-31
DE1111642B (de) 1961-07-27
CH385878A (de) 1964-12-31
NL238796A (US20060009399A1-20060112-C00020.png)
CH388332A (de) 1965-02-28
CH397710A (de) 1965-08-31
CH388334A (de) 1965-02-28
CH396931A (de) 1965-08-15
CY277A (en) 1964-02-12
CH388328A (de) 1965-02-28
US3152173A (en) 1964-10-06
CH388333A (de) 1965-02-28
NL108640C (US20060009399A1-20060112-C00020.png)
OA01363A (fr) 1969-07-04
BE578515A (US20060009399A1-20060112-C00020.png)
FR553M (US20060009399A1-20060112-C00020.png) 1961-05-29

Similar Documents

Publication Publication Date Title
CH388328A (de) Verfahren zur Herstellung von basisch substituierten Diphenylalkan-Derivaten
CH411921A (de) Verfahren zur Herstellung von Aminoacetonitrilen
CH397677A (de) Verfahren zur Herstellung von Aroylalkylpiperidinen
CH377839A (de) Verfahren zur Herstellung von a-Phenylbenzoyl-a-arylaminocarbinolderivaten
CH408015A (de) Verfahren zur Herstellung von 3-Nitro-azacyclo-alkanon-2-N-carbochloriden
CH357724A (de) Verfahren zur Herstellung von Phenothiazinderivaten
CH383960A (de) Verfahren zur Herstellung von gonadenhemmenden Derivaten des 17-epi-Oestriols
CH417104A (de) Verfahren zur Herstellung von Eupolyoxymethylenen
CH387645A (de) Verfahren zur Herstellung von Rhodantriazinen
CH377358A (de) Verfahren zur Herstellung von Di-alkylenimiden
CH387048A (de) Verfahren zur Herstellung von 7-Theophyllinderivaten
CH369133A (de) Verfahren zur Herstellung von substituierten Tetrahydro-oxazinen
CH378312A (de) Verfahren zur Herstellung von Äthinyl-a-oder -b-jonol
CH391722A (de) Verfahren zur Herstellung von 3-Aralkyl-2-tert.-amino-alkyl-indenen
CH374659A (de) Verfahren zur Herstellung von 11-Oxy-steroiden
CH372317A (de) Verfahren zur Herstellung von 5-Nitro-2-furfuryljodid
CH407152A (de) Verfahren zur Herstellung von Diphenylalkan-Derivaten
CH382735A (de) Verfahren zur Herstellung von 16a-Methyl-17a-hydroxyverbindungen der Allopregnanreihe
AT209335B (de) Verfahren zur Herstellung von Dioxopyrazolidinen
AT240538B (de) Verfahren zur Herstellung von 6α-Fluor-16-methylpregnenen und -pregnadienen
CH372662A (de) Verfahren zur Herstellung von 3-Formoxy-17a-hydroxysteroiden
CH388284A (de) Verfahren zur Herstellung von y-Hydroxy-carbonsäureamiden
CH374997A (de) Verfahren zur Herstellung von 4-Methyl-17a-oxyprogesteron
CH383367A (de) Verfahren zur Herstellung von 16-Oxy-pregnadienen
CH441318A (de) Verfahren zur Herstellung von 3-Aminoisoxazolen