CH232529A - Process for the preparation of dimethylamino- (6) -methyl- (2) -heptane. - Google Patents

Process for the preparation of dimethylamino- (6) -methyl- (2) -heptane.

Info

Publication number
CH232529A
CH232529A CH232529DA CH232529A CH 232529 A CH232529 A CH 232529A CH 232529D A CH232529D A CH 232529DA CH 232529 A CH232529 A CH 232529A
Authority
CH
Switzerland
Prior art keywords
heptane
methyl
dimethylamino
preparation
amino
Prior art date
Application number
Other languages
German (de)
Inventor
Fabriken Knoll Ag Chemische
Original Assignee
Knoll Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag filed Critical Knoll Ag
Publication of CH232529A publication Critical patent/CH232529A/en

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

  

      Verfahren    zur Herstellung von     Dimethylamino-(6)-methyl-(2)-heptan.       Gegenstand des     Hauptpatentes    ist ein  Verfahren zur Herstellung von     Methylamino-          (6)-methyl-(2)-heptan,    einer neuen chemi  schen Verbindung mit krampflösender Wir  kung, welches dadurch gekennzeichnet ist, dass  man     Amino-(6)-methyl-(2)--heptan        methyliert.     



  Die vorliegende Erfindung bezieht sich  nun auf die     Herstellung    von     Dimethylamino-          (6)-methyl-,(2)-heptan,    einer neuen und wert  vollen Verbindung, die sich ebenfalls durch  günstige krampflösende Eigenschaften aus  zeichnet.  



  Die neue Verbindung wird     erfindunbms-          gemäss    dadurch hergestellt, dass man auf       Amino-(6)-methyl,-(2)-heptan    Formaldehyd  in     Gegenwart    eines     Reduktionsmittels    ein  wirken lässt.  



  Das     Dimethylamino-(6)-methyl-(2)-heptan     ist eine wasserhelle Flüssigkeit von basischem  Geruch, die bei 176 bis 178  siedet. Sie ist  unlöslich in Wasser, leicht löslich in Säuren  und organischen     Lösungsmitteln.       <I>Beispiel:</I>  64 g     Amino-(6)-methyl-(2)-heptan    werden    in 250 cm' Alkohol gelöst, mit 150 g 88 %     iger          Fürmaldehydlösung    versetzt und in Gegen  wart von Nickel- oder     Ed-elmetallkatalysator     hydriert.

   Nach     beendigter    Reaktion wird mit  verdünnter Mineralsäure versetzt und der  Alkohol     abdestilliert.    Durch Zusatz von  Alkali wird die Base aus der     wäss@rigen          Lösung        abgeschieden    und. hierauf fraktioniert  (Kp. 176 bis 178 ).     Ausbeute:    etwa<B>90%</B> der  Theorie.



      Process for the preparation of dimethylamino- (6) -methyl- (2) -heptane. The subject of the main patent is a process for the production of methylamino- (6) -methyl- (2) -heptane, a new chemical compound with an antispasmodic effect, which is characterized in that amino- (6) -methyl- (2 ) - heptane methylated.



  The present invention now relates to the production of dimethylamino- (6) -methyl -, (2) -heptane, a new and valuable compound, which is also characterized by favorable antispasmodic properties.



  According to the invention, the new compound is prepared by letting formaldehyde act on amino (6) methyl, (2) heptane in the presence of a reducing agent.



  Dimethylamino- (6) -methyl- (2) -heptane is a water-white liquid with a basic odor, which boils at 176 to 178. It is insoluble in water, easily soluble in acids and organic solvents. <I> Example: </I> 64 g of amino- (6) -methyl- (2) -heptane are dissolved in 250 cm 'of alcohol, 150 g of 88% maldehyde solution are added and nickel or ed- Elmetallkatalysator hydrogenated.

   When the reaction has ended, dilute mineral acid is added and the alcohol is distilled off. By adding alkali, the base is separated from the aqueous solution and. then fractionated (cp. 176 to 178). Yield: about <B> 90% </B> of theory.

Claims (1)

PATENTANSPRUCH: Verfahren zur Herstellung von Dimethyl- amino-.(6)-methyl-(2)-heptan, dadurch ge- kennzeichnet, dass, man auf Amino-(6)-methyl- (2)-heptan Formaldehyd in Gegenwart eines Reduktionsmittels einwirken lässt. Die neue Base ist eine farblose Flüssigkeit von basischem Geruch, die bei 176 bis 178 siedet. Sie ist unlöslich in Wasser, leicht löslich in Säuren und organischen Lösungs mitteln. PATENT CLAIM: Process for the production of dimethylamino-. (6) -methyl- (2) -heptane, characterized in that, on amino- (6) -methyl- (2) -heptane, formaldehyde in the presence of a reducing agent can act. The new base is a colorless liquid with a basic odor that boils at 176 to 178. It is insoluble in water, easily soluble in acids and organic solvents.
CH232529D 1937-02-15 1938-02-09 Process for the preparation of dimethylamino- (6) -methyl- (2) -heptane. CH232529A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE232529X 1937-02-15
CH223652T 1938-02-09

Publications (1)

Publication Number Publication Date
CH232529A true CH232529A (en) 1944-05-31

Family

ID=25726729

Family Applications (1)

Application Number Title Priority Date Filing Date
CH232529D CH232529A (en) 1937-02-15 1938-02-09 Process for the preparation of dimethylamino- (6) -methyl- (2) -heptane.

Country Status (1)

Country Link
CH (1) CH232529A (en)

Similar Documents

Publication Publication Date Title
CH232529A (en) Process for the preparation of dimethylamino- (6) -methyl- (2) -heptane.
CH232528A (en) Process for the preparation of dimethylamino- (6) -methyl- (2) -heptane.
CH232532A (en) Process for the preparation of isoamylamino- (6) -methyl- (2) -heptane.
CH217133A (en) Process for the production of a water-soluble, higher molecular weight, α-substituted benzylamine derivative.
CH204708A (en) Process for the preparation of an amino alcohol.
CH232527A (en) Process for the preparation of isoamylamino- (4) -methyl- (2) -pentane.
CH233368A (en) Process for the preparation of isoamylamino- (4) -methyl- (2) -pentane.
CH232531A (en) Process for the preparation of isoamylamino- (6) -methyl- (2) -heptane.
CH217130A (en) Process for the production of a water-soluble, higher molecular weight, α-substituted benzylamine derivative.
CH222904A (en) Process for the preparation of 5-isoamylamino-hexene (1).
CH231665A (en) Process for the preparation of isopropylamino- (6) -methyl- (2) -heptane.
CH208443A (en) Process for the preparation of a lipoid-soluble mixture with bactericidal properties.
CH232530A (en) Process for the preparation of isoamylamino- (6) -methyl- (2) -heptane.
CH232533A (en) Process for the preparation of isoamylamino- (7) -methyl- (2) -octane.
CH208132A (en) Process for the production of a new, nitrogen-containing organic compound.
CH301691A (en) Process for the preparation of a new aromatic thioether.
CH204701A (en) Process for the production of a condensation product.
CH284003A (en) Process for the preparation of a new naphthyridine derivative.
CH210979A (en) Process for the production of a new condensation product.
CH210974A (en) Process for the production of a new condensation product.
CH194876A (en) Process for the preparation of 2 (3 &#39;, 5&#39;-Diiodo-2&#39;-B-oxethyl-4&#39;-oxypheny) - 6-iodoquinoline-4-carboxylic acid.
CH239949A (en) Process for the preparation of a new unsaturated sulfide.
CH144475A (en) Process for obtaining a basic product from a stearoimido ether.
CH301688A (en) Process for the preparation of a new aromatic thioether.
CH223652A (en) Process for the preparation of methylamino- (6) -methyl- (2) -heptane.