CH232532A - Process for the preparation of isoamylamino- (6) -methyl- (2) -heptane. - Google Patents

Process for the preparation of isoamylamino- (6) -methyl- (2) -heptane.

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Publication number
CH232532A
CH232532A CH232532DA CH232532A CH 232532 A CH232532 A CH 232532A CH 232532D A CH232532D A CH 232532DA CH 232532 A CH232532 A CH 232532A
Authority
CH
Switzerland
Prior art keywords
heptane
methyl
preparation
isoamylamino
isopropylamino
Prior art date
Application number
Other languages
German (de)
Inventor
Fabriken Knoll Ag Chemische
Original Assignee
Knoll Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag filed Critical Knoll Ag
Publication of CH232532A publication Critical patent/CH232532A/en

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Description

  

      Verfahren    zur Herstellung     -von        Isopropylamino-(6)-methyl-(2)-heptan.       Gegenstand des     Hauptpatentes    ist ein  Verfahren zur Herstellung von     Methylamino-          (6)-methyl-(2)-heptan,    einer neuen chemi  schen Verbindung mit krampflösender Wir  kung, welches dadurch gekennzeichnet ist, dass  man     Amino-(6)-methyl-(2),-heptan        methyliert.     



  Die vorliegende Erfindung bezieht sich  auf die     Herstellung    von     Isopropylamino-(6)-          methyl-(2)-heptan,    einer neuen und wert  vollen Verbindung, die sich     gleichfalls;    durch  ihre günstige krampflösende Eigenschaft  auszeichnet.  



  Die neue Verbindung wird erfindungs  gemäss dadurch hergestellt, dass man auf       Amino    - (6) -     methyl    - (2) -     heptan        Isopropyl-          halogenid    einwirken     lässt.     



  Das     Isopropylamino    - (6) -     methyl    - (2)     -          heptan    ist eine farblose Flüssigkeit von  basischem Geruch, .die bei     Kp.        "    88     bis    90   siedet. Sie ist unlöslich in Wasser, löslich in  Säuren und organischen Lösungsmitteln.    den unter     Rückfluss        erhitzt,    Nach     Beendigung     der Reaktion wird mit verdünnter Salz  säure neutralisiert und mit Wasserdampf be  handelt.

   Aus der neutralen     wässrigen    Lösung  wird durch Zusatz von Alkali das     Basen-          gemisch        abgeschieden,    aus welchem durch  fraktionierte Destillation     Isopropylamino-(6)-          methyl-(2)-heptan    bei     gp.l,    88     bie.    90  in  reinem Zustand in einer Ausbeute von etwa  85 %     cler    Theorie     .gewonnen    wird.    <I>Beispiel:</I>  64,5g     Amino--(6)-methyl-(2)-heptan    wer  den mit 24,6 g     Isopropylbromid    etwa 6 Stun-



      Process for the preparation of isopropylamino- (6) -methyl- (2) -heptane. The subject of the main patent is a process for the production of methylamino- (6) -methyl- (2) -heptane, a new chemical compound with an antispasmodic effect, which is characterized in that amino- (6) -methyl- (2 ), - heptane methylated.



  The present invention relates to the preparation of isopropylamino- (6) -methyl- (2) -heptane, a new and valuable compound, which is also; characterized by their favorable antispasmodic properties.



  According to the invention, the new compound is produced by allowing isopropyl halide to act on amino (6) methyl (2) heptane.



  Isopropylamino - (6) - methyl - (2) - heptane is a colorless liquid with a basic odor, which boils at bp 88 to 90. It is insoluble in water, soluble in acids and organic solvents, which is heated under reflux After the reaction has ended, it is neutralized with dilute hydrochloric acid and treated with steam.

   The base mixture is separated from the neutral aqueous solution by adding alkali, from which isopropylamino- (6) -methyl- (2) -heptane at gp.l, 88 bie by fractional distillation. 90 is obtained in the pure state in a yield of about 85% of theory. <I> Example: </I> 64.5g amino- (6) -methyl- (2) -heptane are treated with 24.6 g isopropyl bromide for about 6 hours.

 

Claims (1)

PATENTANSPRUCH: Verfahren zur Herstellung von Isopropyl- amino-(6)-methyl-(2)-heptan, dadurch ge kennzeichnet, dass man Amino-(6)-methyl- (2)-heptan und Isopropylhalogenid aufeinan der einwirken lässt. Die neue Base ist eine farblose Flüssig- keit von basischem Geruch, die bei Kp. " 88 bis 90 siedet. PATENT CLAIM: Process for the production of isopropylamino (6) methyl (2) heptane, characterized in that amino (6) methyl (2) heptane and isopropyl halide are allowed to act on one another. The new base is a colorless liquid with a basic odor, which boils at bp 88 to 90. Sie ist unlöslich in. Wasser, löslich in Säuren und organischen Lösungs- mitteln. It is insoluble in water, soluble in acids and organic solvents.
CH232532D 1937-02-15 1938-02-09 Process for the preparation of isoamylamino- (6) -methyl- (2) -heptane. CH232532A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE232532X 1937-02-15
CH223652T 1938-02-09

Publications (1)

Publication Number Publication Date
CH232532A true CH232532A (en) 1944-05-31

Family

ID=25726732

Family Applications (1)

Application Number Title Priority Date Filing Date
CH232532D CH232532A (en) 1937-02-15 1938-02-09 Process for the preparation of isoamylamino- (6) -methyl- (2) -heptane.

Country Status (1)

Country Link
CH (1) CH232532A (en)

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