CH230436A - Process for producing a benzenesulfonic acid amide compound. - Google Patents

Process for producing a benzenesulfonic acid amide compound.

Info

Publication number
CH230436A
CH230436A CH230436DA CH230436A CH 230436 A CH230436 A CH 230436A CH 230436D A CH230436D A CH 230436DA CH 230436 A CH230436 A CH 230436A
Authority
CH
Switzerland
Prior art keywords
acid amide
producing
amide compound
benzenesulfonic acid
dibromomethyl
Prior art date
Application number
Other languages
German (de)
Inventor
Aktiengesellsc Farbenindustrie
Original Assignee
Ig Farbenindustrie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ig Farbenindustrie Ag filed Critical Ig Farbenindustrie Ag
Publication of CH230436A publication Critical patent/CH230436A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

  

  Verfahren zur Herstellung einer     Benzolsulfonsäureamidverbindung.            Gegenstand    des vorliegenden     Patentes        ist     ein Verfahren zur     Herstellung    von     4-Dibrom-          methyl-benzolsulfonsäureamid,    das dadurch  gekennzeichnet ist, dass man ein     4-Dibrom-          methyl-benzolsulfonsäurehaJogeni.d    mit Am  moniak umsetzt. Die Umsetzung wird zweck  mässig     bei    Temperaturen unter 60  durchge  führt.  



  Das erhaltene neue Produkt bildet farb  lose     Kristalle    vom Schmelzpunkt 174 . Es  soll als pharmazeutisches Produkt     bezw.    als       Zwischenprodukt    zum Aufbau von pharma  zeutischen     Produkten        Verwendung    finden.    <I>Beispiel:</I>    <B>35</B> g     4-Dibrommethyl-benzoIsulfonsäure-          ch        lorid    werden in 100 cm' Alkohol gelöst. In  die Lösung trägt man 25 cm' 20 %     iges        wäss-          riges    Ammoniak ein, wobei man .die Tempe  ratur nicht über 40-50      steigen    lässt.

   Beim  Abkühlen erstarrt die Lösung zu     einem       Kristallbrei von 4 -     Dibrommethyl    -     benzol-          sulfonsäureamd.    Es     wird    nach. dem Absau  gen gut     ausgewaschen    und     aus    Alkohol in  Form farbloser Kristalle vom Schmelzpunkt  174      erhalten.  



  Process for producing a benzenesulfonic acid amide compound. The subject matter of the present patent is a process for the preparation of 4-dibromomethyl-benzenesulphonic acid amide, which is characterized in that a 4-dibromomethyl-benzenesulphonic acid halogenide is reacted with ammonia. The reaction is expediently carried out at temperatures below 60 °.



  The new product obtained forms colorless crystals with a melting point of 174. It should bezw as a pharmaceutical product. find use as an intermediate product for the construction of pharmaceutical products. <I> Example: </I> <B> 35 </B> g of 4-dibromomethylbenzoisulfonic acid chloride are dissolved in 100 cm of alcohol. 25 cm 2 of 20% strength aqueous ammonia are introduced into the solution, the temperature not being allowed to rise above 40-50.

   On cooling, the solution solidifies to form a crystal slurry of 4 - dibromomethyl - benzene sulfonic acid amd. It will after. The Absau conditions are well washed out and obtained from alcohol in the form of colorless crystals with a melting point of 174.

Claims (1)

PATENTANSPRUCH: Verfahren zur Herstellung von 4-Dibrom- methyl-benzolsulfouGäureamid, da,durch ge kennzeichnet, dass man ein 4-Dibrommethyl- benzolsulfonsäurehalob nid mit Ammoniak umsetzt. Das so erhältliche Produkt bildet farblose KristaLe vom .Schmelzpunkt l74 . PATENT CLAIM: Process for the production of 4-dibromomethyl-benzenesulfuramide, as indicated by that a 4-dibromomethylbenzenesulfonic acid halide is reacted with ammonia. The product obtainable in this way forms colorless crystals with a melting point of 174. UNTERANSPRUCH: Verfahren nach Patentanspruch, dadurch gekennzeichnet, dass man bei Temperaturen unter 60 arbeitet. SUBCLAIM: Method according to claim, characterized in that temperatures below 60 are used.
CH230436D 1940-08-08 1941-06-12 Process for producing a benzenesulfonic acid amide compound. CH230436A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE230436X 1940-08-08
CH223947T 1941-06-12

Publications (1)

Publication Number Publication Date
CH230436A true CH230436A (en) 1943-12-31

Family

ID=25726757

Family Applications (1)

Application Number Title Priority Date Filing Date
CH230436D CH230436A (en) 1940-08-08 1941-06-12 Process for producing a benzenesulfonic acid amide compound.

Country Status (1)

Country Link
CH (1) CH230436A (en)

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