CH230437A - Process for producing a benzenesulfonic acid amide compound. - Google Patents

Process for producing a benzenesulfonic acid amide compound.

Info

Publication number
CH230437A
CH230437A CH230437DA CH230437A CH 230437 A CH230437 A CH 230437A CH 230437D A CH230437D A CH 230437DA CH 230437 A CH230437 A CH 230437A
Authority
CH
Switzerland
Prior art keywords
benzenesulfonic acid
acid amide
producing
amide compound
chloromethyl
Prior art date
Application number
Other languages
German (de)
Inventor
Aktiengesellsc Farbenindustrie
Original Assignee
Ig Farbenindustrie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ig Farbenindustrie Ag filed Critical Ig Farbenindustrie Ag
Publication of CH230437A publication Critical patent/CH230437A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

  

      Verfahren    zur Herstellung einer     Benzolsulfonsäureamidverbindung.       Gegenstand des vorliegenden Patentes ist  ein Verfahren zur Herstellung von     4-Chlor-          methyl-benzolsulfonsäureamid,    das dadurch  gekennzeichnet ist, dass man ein     4-Chlor-          methyl-benzolsulfonsäurehalogenid    mit     Am-          moniali:    umsetzt.  



  Das neue Verfahrensprodukt bildet glän  zende Blättchen vom Schmelzpunkt 165 .  Es soll als pharmazeutisches Produkt     bezw.     als Zwischenprodukt zum Aufbau von phar  mazeutischen Produkten Verwendung finden.       Beispiel:     In die Lösung von 23 g     4-Chlormethyl-          benzolsulfonsäurechlorid    in 75 cm' Alkohol  werden unter Kühlung und Rühren 20     cm3     20      /oiges        wässriges    Ammoniak     zutropfen    ge  lassen. Die Temperatur wird dabei unter 20   gehalten und nach Zugabe des Ammoniaks  noch 10-15 Minuten weiter gerührt.

   Es bil  det sieh ein dicker Kristallbrei des 4-Chlor-         methyl-benzolsulfonsäureamids,    das nach dem  Absaugen mit Wasser gut ausgewaschen  wird. Aus Alkohol erhält man es in glän  zenden Blättchen vom     Schmelzpunkt    165 .



      Process for producing a benzenesulfonic acid amide compound. The present patent relates to a process for the preparation of 4-chloromethyl-benzenesulfonic acid amide, which is characterized in that a 4-chloromethyl-benzenesulfonic acid halide is reacted with ammonia.



  The new process product forms shiny flakes with a melting point of 165. It should bezw as a pharmaceutical product. find use as an intermediate in the construction of pharmaceutical products. Example: 20 cm3 of 20% aqueous ammonia are added dropwise to the solution of 23 g of 4-chloromethylbenzenesulfonic acid chloride in 75 cm of alcohol, while cooling and stirring. The temperature is kept below 20 and, after the ammonia has been added, stirring is continued for 10-15 minutes.

   A thick crystal slurry of 4-chloromethyl-benzenesulfonic acid amide forms, which is washed out thoroughly with water after suction. It is obtained from alcohol in shiny leaves with a melting point of 165.

Claims (1)

PATENTANSPRUCH: Verfahren zur Herstellung von 4-Chlor- methyl-benzolsulfonsäureamid, dadurch ge kennzeichnet, dass man ein 4-Chlormetliyl- benzolsulfonsäurehalogenid mit Ammoniak umsetzt. Das so erhältliche Produkt bildet glän zende Blättchen vom Schmelzpunkt 165 . UNTERANSPRUCH: Verfahren nach Patentanspruch, dadurch gekennzeichnet, dass man bei Temperaturen unter 60 arbeitet. PATENT CLAIM: Process for the production of 4-chloromethyl-benzenesulfonic acid amide, characterized in that a 4-chloromethyl-benzenesulfonic acid halide is reacted with ammonia. The product obtainable in this way forms shiny flakes with a melting point of 165. SUBCLAIM: Process according to claim, characterized in that temperatures below 60 are used.
CH230437D 1941-06-12 1941-06-12 Process for producing a benzenesulfonic acid amide compound. CH230437A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH223947T 1941-06-12

Publications (1)

Publication Number Publication Date
CH230437A true CH230437A (en) 1943-12-31

Family

ID=4453286

Family Applications (1)

Application Number Title Priority Date Filing Date
CH230437D CH230437A (en) 1941-06-12 1941-06-12 Process for producing a benzenesulfonic acid amide compound.

Country Status (1)

Country Link
CH (1) CH230437A (en)

Similar Documents

Publication Publication Date Title
CH230437A (en) Process for producing a benzenesulfonic acid amide compound.
CH230438A (en) Process for producing a benzenesulfonic acid amide compound.
CH257944A (en) Process for the production of a vat dye.
AT298438B (en) Process for the production of aspartic acid
AT105596B (en) Process for the preparation of p-methoxy-o-acetoxybenzoic acid.
CH189302A (en) Process for the production of a new textile auxiliary.
CH220971A (en) Process for the preparation of a condensation product.
CH110414A (en) Process for the preparation of an anthracene derivative.
CH299273A (en) Process for the production of a thiosemicarbazone.
CH299272A (en) Process for the production of a thiosemicarbazone.
CH187421A (en) Process for the production of a new textile auxiliary.
CH184173A (en) Process for the preparation of a secondary alkylamine.
CH249002A (en) Process for the preparation of a new amide derivative.
CH265713A (en) Process for the preparation of a new derivative of 4-methyl-7-amino-coumarin.
CH230436A (en) Process for producing a benzenesulfonic acid amide compound.
CH309830A (en) Process for producing a hydrazine compound.
CH210970A (en) Process for the preparation of a urea derivative.
CH126194A (en) Process for the preparation of a benzobenzanthronecarboxylic acid.
CH240580A (en) Process for the preparation of p-amino-benzenesulfonylguanidine.
CH252959A (en) Process for the preparation of a new benzenesulfonylguanidine.
CH295836A (en) Process for the preparation of a product of the thiosemicarbazone series.
CH92297A (en) Process for the preparation of a condensation product from B-imidazolylethylamine.
CH314214A (en) Process for the preparation of a quaternary ammonium salt
CH202370A (en) Process for preparing a sulfonic acid amide compound.
CH210969A (en) Process for the preparation of a urea derivative.