CH184422A - Process for the preparation of 2-methyl-4-aminoquinolyl-6-melamine. - Google Patents
Process for the preparation of 2-methyl-4-aminoquinolyl-6-melamine.Info
- Publication number
- CH184422A CH184422A CH184422DA CH184422A CH 184422 A CH184422 A CH 184422A CH 184422D A CH184422D A CH 184422DA CH 184422 A CH184422 A CH 184422A
- Authority
- CH
- Switzerland
- Prior art keywords
- methyl
- melamine
- preparation
- aminoquinolyl
- mole
- Prior art date
Links
Description
\'erfahren zur Herstellung von 2-Nethyl-4-aminochinolyl-6-melamin. Gegenstand des vorliegenden Patentes ist ein Verfahren zur Herstellung von 2 Methyl-4-aminochinolyl-6-melamin, das da durch gekennzeichnet ist, dass man etwa ein Mol 4.6-Diamirro-2-methyl-chinolirr mit etwa einem Mol Chlorcyanurdiamid umsetzt.
Die neue Verbindung bildet ein wasser lösliches Hydrochlorid, sie schmilzt bei<B>267'</B> unter Dunkelfärbung. Sie soll als Arznei mittel Verwendung finden.
<I>Beispiel:</I> 3,5 g 4.6-Diarmirro-2-methylchinolin wer den in 35 cm' Nitrobenzol bei etwa 120 gelöst. Nach Zugabe von 3 g Chlorcyanur- diamid (Berichte 32 [1899], S. 695) wird die Temperatur unter Rühren etwa 3 Stunden bei 150 gehalten. Nach dem Erkalten wird mit Äther versetzt, der gebildete Niederschlag abgesaugt, mit verdünnter Essigsäure aus- gekocht und der Auszug ammoniakalisch gemacht.
Die dadurch ausgefällte rohe Base kann durch wiederholtes Umkristallisieren aus Wasser und Äthanol gereinigt werden und erweist sich als identisch mit der im Hauptpatent Nr. 176485 beschriebenen Ver bindung.
\ 'experienced in the production of 2-Nethyl-4-aminochinolyl-6-melamine. The subject of the present patent is a process for the preparation of 2-methyl-4-aminochinolyl-6-melamine, which is characterized in that about one mole of 4,6-diamirro-2-methyl-quinolir is reacted with about one mole of cyanuric chloride.
The new compound forms a water-soluble hydrochloride, it melts at <B> 267 '</B> with a dark color. It should be used as a medicament.
<I> Example: </I> 3.5 g of 4,6-diarmirro-2-methylquinoline are dissolved in 35 cm 'nitrobenzene at about 120. After adding 3 g of cyanogen chloride (Reports 32 [1899], p. 695), the temperature is kept at 150 for about 3 hours while stirring. After cooling, ether is added, the precipitate formed is suctioned off, boiled with dilute acetic acid and the extract is made ammoniacal.
The crude base thus precipitated can be purified by repeated recrystallization from water and ethanol and is found to be identical to the compound described in main patent no. 176485.
Claims (1)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE184422X | 1932-11-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH184422A true CH184422A (en) | 1936-05-31 |
Family
ID=5719005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH184422D CH184422A (en) | 1932-11-04 | 1933-10-04 | Process for the preparation of 2-methyl-4-aminoquinolyl-6-melamine. |
Country Status (1)
| Country | Link |
|---|---|
| CH (1) | CH184422A (en) |
-
1933
- 1933-10-04 CH CH184422D patent/CH184422A/en unknown
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