CA989404A - N-tertiaire aminomethyl-4' dibenzo(b,e)oxepine-11 spiro-2'-dioxolanne-1',3', leur procede de preparation et leur application en therapeutique - Google Patents
N-tertiaire aminomethyl-4' dibenzo(b,e)oxepine-11 spiro-2'-dioxolanne-1',3', leur procede de preparation et leur application en therapeutiqueInfo
- Publication number
- CA989404A CA989404A CA143,363A CA143363A CA989404A CA 989404 A CA989404 A CA 989404A CA 143363 A CA143363 A CA 143363A CA 989404 A CA989404 A CA 989404A
- Authority
- CA
- Canada
- Prior art keywords
- dioxolanne
- oxepine
- dibenzo
- spiro
- preparation process
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7119501A FR2139651A1 (en) | 1971-05-28 | 1971-05-28 | 4'-n-tert-amino-methyl-2'-(dibenzo (b,e) oxepine-11-spiro) - 1',3'-dioxolan - analgesic, respiratory analeptic, antitussive, broch |
| FR7210250A FR2176561A2 (en) | 1972-03-23 | 1972-03-23 | 4'-n-tert-amino-methyl-2'-(dibenzo (b,e) oxepine-11-spiro) - 1',3'-dioxolan - analgesic, respiratory analeptic, antitussive, broch |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA989404A true CA989404A (fr) | 1976-05-18 |
Family
ID=26216420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA143,363A Expired CA989404A (fr) | 1971-05-28 | 1972-05-26 | N-tertiaire aminomethyl-4' dibenzo(b,e)oxepine-11 spiro-2'-dioxolanne-1',3', leur procede de preparation et leur application en therapeutique |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US3845046A (xx) |
| JP (1) | JPS5218196B1 (xx) |
| AR (1) | AR192786A1 (xx) |
| AU (1) | AU465949B2 (xx) |
| BE (1) | BE783499A (xx) |
| CA (1) | CA989404A (xx) |
| CH (1) | CH532034A (xx) |
| CS (1) | CS181224B2 (xx) |
| DE (1) | DE2225245C3 (xx) |
| GB (1) | GB1359951A (xx) |
| IL (1) | IL39496A (xx) |
| IT (1) | IT1052682B (xx) |
| LU (1) | LU65380A1 (xx) |
| NL (1) | NL7207229A (xx) |
| SE (1) | SE373583B (xx) |
| SU (1) | SU420174A3 (xx) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4048164A (en) * | 1971-06-18 | 1977-09-13 | Delalande S.A. | N'-substituted derivatives of 4'-(N-piperazinylmethyl)spiro dibenzocycloheptadi- (or tri-) ene-5,2'-dioxolane(1',3') |
| EP0295209A3 (de) * | 1987-06-10 | 1990-01-24 | Ciba-Geigy Ag | Orthokohlensäureester |
| US6063794A (en) * | 1996-10-11 | 2000-05-16 | Cor Therapeutics Inc. | Selective factor Xa inhibitors |
| US6369080B2 (en) | 1996-10-11 | 2002-04-09 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
| US6262047B1 (en) | 1996-10-11 | 2001-07-17 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
| US6194435B1 (en) | 1996-10-11 | 2001-02-27 | Cor Therapeutics, Inc. | Lactams as selective factor Xa inhibitors |
| WO1998046591A1 (en) * | 1997-04-14 | 1998-10-22 | Cor Therapeutics, Inc. | SELECTIVE FACTOR Xa INHIBITORS |
| AU6896298A (en) | 1997-04-14 | 1998-11-11 | Cor Therapeutics, Inc. | Selective factor xa inhibitors |
| EP0977773A1 (en) | 1997-04-14 | 2000-02-09 | Cor Therapeutics, Inc. | SELECTIVE FACTOR Xa INHIBITORS |
| JP2001521524A (ja) * | 1997-04-14 | 2001-11-06 | シーオーアール セラピューティクス インコーポレイテッド | 選択的Ｘａ因子阻害剤 |
| US6333321B1 (en) | 1997-08-11 | 2001-12-25 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
| US6218382B1 (en) | 1997-08-11 | 2001-04-17 | Cor Therapeutics, Inc | Selective factor Xa inhibitors |
| US6228854B1 (en) | 1997-08-11 | 2001-05-08 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
| CA2520680A1 (en) * | 2003-03-31 | 2004-10-14 | Kyowa Hakko Kogyo Co., Ltd. | Antitussives |
-
1972
- 1972-05-15 BE BE783499A patent/BE783499A/xx unknown
- 1972-05-17 LU LU65380A patent/LU65380A1/xx unknown
- 1972-05-22 IL IL39496A patent/IL39496A/xx unknown
- 1972-05-22 GB GB2391572A patent/GB1359951A/en not_active Expired
- 1972-05-23 CH CH757472A patent/CH532034A/fr not_active IP Right Cessation
- 1972-05-24 DE DE2225245A patent/DE2225245C3/de not_active Expired
- 1972-05-25 US US00256655A patent/US3845046A/en not_active Expired - Lifetime
- 1972-05-26 SE SE7206954A patent/SE373583B/xx unknown
- 1972-05-26 AU AU42788/72A patent/AU465949B2/en not_active Expired
- 1972-05-26 CA CA143,363A patent/CA989404A/fr not_active Expired
- 1972-05-26 CS CS7200003650A patent/CS181224B2/cs unknown
- 1972-05-26 SU SU1788862A patent/SU420174A3/ru active
- 1972-05-26 AR AR242209A patent/AR192786A1/es active
- 1972-05-27 IT IT68696/72A patent/IT1052682B/it active
- 1972-05-29 NL NL7207229A patent/NL7207229A/xx not_active Application Discontinuation
- 1972-05-29 JP JP47052583A patent/JPS5218196B1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE2225245B2 (de) | 1978-03-02 |
| DE2225245C3 (de) | 1978-11-02 |
| IL39496A0 (en) | 1972-07-26 |
| IT1052682B (it) | 1981-07-20 |
| AU465949B2 (en) | 1975-10-09 |
| NL7207229A (xx) | 1972-11-30 |
| AU4278872A (en) | 1973-11-29 |
| CS181224B2 (en) | 1978-03-31 |
| SE373583B (sv) | 1975-02-10 |
| DE2225245A1 (de) | 1973-01-04 |
| BE783499A (fr) | 1972-11-16 |
| CH532034A (fr) | 1972-12-31 |
| US3845046A (en) | 1974-10-29 |
| LU65380A1 (xx) | 1973-01-22 |
| GB1359951A (en) | 1974-07-17 |
| IL39496A (en) | 1975-04-25 |
| JPS5218196B1 (xx) | 1977-05-20 |
| AR192786A1 (es) | 1973-03-14 |
| SU420174A3 (ru) | 1974-03-15 |
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