BE783499A - N-tertiaire aminomethyl-4' dibenzo (b,e) oxepine-11-spiro- 2'-dioxolanne-1',3', leur procede de preparation et leur application en therapeutique - Google Patents

N-tertiaire aminomethyl-4' dibenzo (b,e) oxepine-11-spiro- 2'-dioxolanne-1',3', leur procede de preparation et leur application en therapeutique

Info

Publication number
BE783499A
BE783499A BE783499A BE783499A BE783499A BE 783499 A BE783499 A BE 783499A BE 783499 A BE783499 A BE 783499A BE 783499 A BE783499 A BE 783499A BE 783499 A BE783499 A BE 783499A
Authority
BE
Belgium
Prior art keywords
dioxolanne
tertiaire
oxepine
dibenzo
aminomethyl
Prior art date
Application number
BE783499A
Other languages
English (en)
French (fr)
Inventor
C Fauran
A-Y Le Cloarec
G Raynaud
B Pourrias
J Eberle
Original Assignee
Delalande Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7119501A external-priority patent/FR2139651A1/fr
Priority claimed from FR7210250A external-priority patent/FR2176561A2/fr
Application filed by Delalande Sa filed Critical Delalande Sa
Publication of BE783499A publication Critical patent/BE783499A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BE783499A 1971-05-28 1972-05-15 N-tertiaire aminomethyl-4' dibenzo (b,e) oxepine-11-spiro- 2'-dioxolanne-1',3', leur procede de preparation et leur application en therapeutique BE783499A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7119501A FR2139651A1 (en) 1971-05-28 1971-05-28 4'-n-tert-amino-methyl-2'-(dibenzo (b,e) oxepine-11-spiro) - 1',3'-dioxolan - analgesic, respiratory analeptic, antitussive, broch
FR7210250A FR2176561A2 (en) 1972-03-23 1972-03-23 4'-n-tert-amino-methyl-2'-(dibenzo (b,e) oxepine-11-spiro) - 1',3'-dioxolan - analgesic, respiratory analeptic, antitussive, broch

Publications (1)

Publication Number Publication Date
BE783499A true BE783499A (fr) 1972-11-16

Family

ID=26216420

Family Applications (1)

Application Number Title Priority Date Filing Date
BE783499A BE783499A (fr) 1971-05-28 1972-05-15 N-tertiaire aminomethyl-4' dibenzo (b,e) oxepine-11-spiro- 2'-dioxolanne-1',3', leur procede de preparation et leur application en therapeutique

Country Status (16)

Country Link
US (1) US3845046A (xx)
JP (1) JPS5218196B1 (xx)
AR (1) AR192786A1 (xx)
AU (1) AU465949B2 (xx)
BE (1) BE783499A (xx)
CA (1) CA989404A (xx)
CH (1) CH532034A (xx)
CS (1) CS181224B2 (xx)
DE (1) DE2225245C3 (xx)
GB (1) GB1359951A (xx)
IL (1) IL39496A (xx)
IT (1) IT1052682B (xx)
LU (1) LU65380A1 (xx)
NL (1) NL7207229A (xx)
SE (1) SE373583B (xx)
SU (1) SU420174A3 (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4048164A (en) * 1971-06-18 1977-09-13 Delalande S.A. N'-substituted derivatives of 4'-(N-piperazinylmethyl)spiro dibenzocycloheptadi- (or tri-) ene-5,2'-dioxolane(1',3')
EP0295209A3 (de) * 1987-06-10 1990-01-24 Ciba-Geigy Ag Orthokohlensäureester
US6063794A (en) * 1996-10-11 2000-05-16 Cor Therapeutics Inc. Selective factor Xa inhibitors
US6369080B2 (en) 1996-10-11 2002-04-09 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6262047B1 (en) 1996-10-11 2001-07-17 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6194435B1 (en) 1996-10-11 2001-02-27 Cor Therapeutics, Inc. Lactams as selective factor Xa inhibitors
US6133256A (en) * 1997-04-14 2000-10-17 Cor Therapeutics Inc Selective factor Xa inhibitors
AU6896398A (en) 1997-04-14 1998-11-11 Cor Therapeutics, Inc. Selective factor xa inhibitors
JP2002513412A (ja) * 1997-04-14 2002-05-08 シーオーアール セラピューティクス インコーポレイテッド 選択的Ｘａ因子阻害剤
AU6896298A (en) 1997-04-14 1998-11-11 Cor Therapeutics, Inc. Selective factor xa inhibitors
US6228854B1 (en) 1997-08-11 2001-05-08 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6333321B1 (en) 1997-08-11 2001-12-25 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6218382B1 (en) 1997-08-11 2001-04-17 Cor Therapeutics, Inc Selective factor Xa inhibitors
US20060205756A1 (en) * 2003-03-31 2006-09-14 Kyowa Hakko Kogyo Co., Ltd. Antitussives

Also Published As

Publication number Publication date
JPS5218196B1 (xx) 1977-05-20
AR192786A1 (es) 1973-03-14
IL39496A (en) 1975-04-25
DE2225245A1 (de) 1973-01-04
CH532034A (fr) 1972-12-31
AU465949B2 (en) 1975-10-09
LU65380A1 (xx) 1973-01-22
US3845046A (en) 1974-10-29
DE2225245C3 (de) 1978-11-02
SU420174A3 (ru) 1974-03-15
IL39496A0 (en) 1972-07-26
IT1052682B (it) 1981-07-20
CS181224B2 (en) 1978-03-31
CA989404A (fr) 1976-05-18
DE2225245B2 (de) 1978-03-02
SE373583B (sv) 1975-02-10
AU4278872A (en) 1973-11-29
GB1359951A (en) 1974-07-17
NL7207229A (xx) 1972-11-30

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