CA967158A - Benzylpyrimidines - Google Patents

Benzylpyrimidines

Info

Publication number
CA967158A
CA967158A CA125,807A CA125807A CA967158A CA 967158 A CA967158 A CA 967158A CA 125807 A CA125807 A CA 125807A CA 967158 A CA967158 A CA 967158A
Authority
CA
Canada
Prior art keywords
benzylpyrimidines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA125,807A
Other languages
English (en)
Other versions
CA125807S (en
Inventor
Thomas Paterson
Alexander Stuart
Barbara Roth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Priority to CA205,203A priority Critical patent/CA999583A/en
Application granted granted Critical
Publication of CA967158A publication Critical patent/CA967158A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA125,807A 1970-10-22 1971-10-21 Benzylpyrimidines Expired CA967158A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA205,203A CA999583A (en) 1970-10-22 1974-07-19 Intermediates for benzylpyrimides

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB963871*[A GB1375162A (US08067413-20111129-C00029.png) 1970-10-22 1970-10-22
GB963871 1971-04-16
GB4749171 1971-10-12

Publications (1)

Publication Number Publication Date
CA967158A true CA967158A (en) 1975-05-06

Family

ID=27255400

Family Applications (1)

Application Number Title Priority Date Filing Date
CA125,807A Expired CA967158A (en) 1970-10-22 1971-10-21 Benzylpyrimidines

Country Status (20)

Country Link
JP (2) JPS5536662B1 (US08067413-20111129-C00029.png)
AR (3) AR192588A1 (US08067413-20111129-C00029.png)
AT (1) AT319948B (US08067413-20111129-C00029.png)
BE (1) BE774281A (US08067413-20111129-C00029.png)
BG (4) BG20797A3 (US08067413-20111129-C00029.png)
CA (1) CA967158A (US08067413-20111129-C00029.png)
CH (3) CH568301A5 (US08067413-20111129-C00029.png)
DD (1) DD100877A5 (US08067413-20111129-C00029.png)
DK (1) DK132174C (US08067413-20111129-C00029.png)
ES (1) ES396219A1 (US08067413-20111129-C00029.png)
FI (1) FI56175C (US08067413-20111129-C00029.png)
FR (1) FR2111769B1 (US08067413-20111129-C00029.png)
GB (1) GB1375162A (US08067413-20111129-C00029.png)
IE (1) IE37452B1 (US08067413-20111129-C00029.png)
IL (2) IL45422A (US08067413-20111129-C00029.png)
LU (1) LU64129A1 (US08067413-20111129-C00029.png)
MC (1) MC894A1 (US08067413-20111129-C00029.png)
NL (1) NL175178C (US08067413-20111129-C00029.png)
SE (2) SE384505B (US08067413-20111129-C00029.png)
ZM (1) ZM14971A1 (US08067413-20111129-C00029.png)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE792096A (fr) * 1971-12-01 1973-05-30 Hoffmann La Roche Nouvelles benzylpyrimidines
FR2397407A2 (fr) * 1977-07-11 1979-02-09 Dick Pierre Derives de 2,4-diamino pyrimidines et leur mise en solution en association avec des sulfamides
NO791699L (no) * 1978-05-24 1979-11-27 Wellcome Found Benzylpyrimidinforbindelser og fremgangsmaate til deres fremstilling
JPS61156909A (ja) * 1984-12-27 1986-07-16 Matsushita Electric Ind Co Ltd カレント・ミラ−回路
JPS62145907A (ja) * 1985-12-20 1987-06-30 Hitachi Ltd トランジスタ回路
TWI414525B (zh) 2004-03-26 2013-11-11 Dainippon Sumitomo Pharma Co 9-取代-8-氧基腺嘌呤化合物
US8138172B2 (en) 2006-07-05 2012-03-20 Astrazeneca Ab 8-oxoadenine derivatives acting as modulators of TLR7
TW200831105A (en) 2006-12-14 2008-08-01 Astrazeneca Ab Novel compounds
WO2008114006A1 (en) 2007-03-19 2008-09-25 Astrazeneca Ab 9-substituted-8-oxo-adenine compounds as toll-like receptor (tlr7) modulators
PT2132209E (pt) 2007-03-19 2014-04-15 Astrazeneca Ab Compostos de 8-oxo-adenina substituídos na posição 9, como moduladores do recetor de tipo ¿toll¿ (tlr7)
EP2138497A4 (en) 2007-03-20 2012-01-04 Dainippon Sumitomo Pharma Co NEW ADENINE CONNECTION
PE20091236A1 (es) * 2007-11-22 2009-09-16 Astrazeneca Ab Derivados de pirimidina como immunomoduladores de tlr7
PE20091156A1 (es) 2007-12-17 2009-09-03 Astrazeneca Ab Sales de (3-{[[3-(6-amino-2-butoxi-8-oxo-7,8-dihidro-9h-purin-9-il)propil](3-morfolin-4-ilpropil)amino]metil}fenil)acetato de metilo
CN102482233A (zh) 2009-05-21 2012-05-30 阿斯利康(瑞典)有限公司 新颖的嘧啶衍生物和它们在治疗癌症和其它疾病中的用途
GB0908772D0 (en) 2009-05-21 2009-07-01 Astrazeneca Ab New salts 756
ES2575688T3 (es) 2010-12-16 2016-06-30 Sumitomo Dainippon Pharma Co., Ltd. Derivado de imidazo[4,5-c]quinolin-1-ilo útil en terapia
US8895570B2 (en) 2010-12-17 2014-11-25 Astrazeneca Ab Purine derivatives
CN104302628B (zh) 2012-05-18 2017-06-23 大日本住友制药株式会社 羧酸化合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE710100A (US08067413-20111129-C00029.png) * 1967-02-02 1968-07-30
JPS511716A (ja) * 1974-06-25 1976-01-08 Toray Industries Horiesuterumaruchifuiramentono seiho

Also Published As

Publication number Publication date
BE774281A (fr) 1972-04-21
AT319948B (de) 1975-01-10
JPS5536662B1 (US08067413-20111129-C00029.png) 1980-09-22
SE384505B (sv) 1976-05-10
NL175178B (nl) 1984-05-01
MC894A1 (fr) 1972-06-22
DK132174B (da) 1975-11-03
BG21406A3 (bg) 1976-05-20
BG20797A3 (bg) 1975-12-20
CH568302A5 (US08067413-20111129-C00029.png) 1975-10-31
AR192588A1 (es) 1973-02-28
AR192802A1 (es) 1973-03-14
IL37984A0 (en) 1971-12-29
FR2111769B1 (US08067413-20111129-C00029.png) 1974-10-18
ES396219A1 (es) 1975-09-16
ZM14971A1 (en) 1972-07-21
BG20364A3 (bg) 1975-11-05
FI56175C (fi) 1979-12-10
NL7114494A (US08067413-20111129-C00029.png) 1972-04-25
LU64129A1 (US08067413-20111129-C00029.png) 1972-06-28
CH568301A5 (US08067413-20111129-C00029.png) 1975-10-31
CH582681A5 (US08067413-20111129-C00029.png) 1976-12-15
JPS53135991A (en) 1978-11-28
NL175178C (nl) 1984-10-01
SE409705B (sv) 1979-09-03
IL37984A (en) 1976-03-31
FR2111769A1 (US08067413-20111129-C00029.png) 1972-06-09
IL45422A (en) 1976-03-31
DD100877A5 (US08067413-20111129-C00029.png) 1973-10-12
DK132174C (da) 1976-03-29
IE37452B1 (en) 1977-08-03
GB1375162A (US08067413-20111129-C00029.png) 1974-11-27
FI56175B (fi) 1979-08-31
BG20365A3 (bg) 1975-11-05
AR192803A1 (es) 1973-03-14
IE37452L (en) 1972-04-22

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