CA3243809A1 - ANTIBIOTIC COMPOUNDS, FORMULATIONS AND METHODS OF USE - Google Patents
ANTIBIOTIC COMPOUNDS, FORMULATIONS AND METHODS OF USEInfo
- Publication number
- CA3243809A1 CA3243809A1 CA3243809A CA3243809A CA3243809A1 CA 3243809 A1 CA3243809 A1 CA 3243809A1 CA 3243809 A CA3243809 A CA 3243809A CA 3243809 A CA3243809 A CA 3243809A CA 3243809 A1 CA3243809 A1 CA 3243809A1
- Authority
- CA
- Canada
- Prior art keywords
- optionally substituted
- moiety
- polymyxin
- amino
- substituted alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
- C07K7/62—Polymyxins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL2030897A NL2030897B1 (en) | 2022-02-11 | 2022-02-11 | Antibiotic compounds, formulations and methods of use |
| NL2030897 | 2022-02-11 | ||
| PCT/NL2023/050065 WO2023153932A1 (en) | 2022-02-11 | 2023-02-13 | Antibiotic compounds, formulations and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3243809A1 true CA3243809A1 (en) | 2023-08-17 |
Family
ID=85283807
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3243809A Pending CA3243809A1 (en) | 2022-02-11 | 2023-02-13 | ANTIBIOTIC COMPOUNDS, FORMULATIONS AND METHODS OF USE |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20250171498A1 (https=) |
| EP (1) | EP4476239A1 (https=) |
| JP (1) | JP2025505237A (https=) |
| CN (1) | CN118871454A (https=) |
| CA (1) | CA3243809A1 (https=) |
| NL (1) | NL2030897B1 (https=) |
| WO (1) | WO2023153932A1 (https=) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112014012016A2 (pt) * | 2011-11-18 | 2017-05-16 | Cantab Anti-Infectives Ltd | compostos |
| EP3636659A1 (en) * | 2018-10-08 | 2020-04-15 | Universitat de Barcelona | Polymyxin-based compounds useful as antibacterial agents |
| WO2021150792A1 (en) * | 2020-01-21 | 2021-07-29 | Micurx Pharmaceuticals, Inc. | Novel compounds and composition for targeted therapy of kidney-associated cancers |
| CN118201946A (zh) * | 2021-08-12 | 2024-06-14 | 奥克兰联合服务有限公司 | 脂化多粘菌素类似物 |
-
2022
- 2022-02-11 NL NL2030897A patent/NL2030897B1/en active
-
2023
- 2023-02-13 EP EP23706119.7A patent/EP4476239A1/en active Pending
- 2023-02-13 WO PCT/NL2023/050065 patent/WO2023153932A1/en not_active Ceased
- 2023-02-13 CN CN202380025983.1A patent/CN118871454A/zh active Pending
- 2023-02-13 JP JP2024547475A patent/JP2025505237A/ja active Pending
- 2023-02-13 CA CA3243809A patent/CA3243809A1/en active Pending
- 2023-02-13 US US18/836,507 patent/US20250171498A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2025505237A (ja) | 2025-02-21 |
| US20250171498A1 (en) | 2025-05-29 |
| CN118871454A (zh) | 2024-10-29 |
| NL2030897B1 (en) | 2023-08-18 |
| WO2023153932A1 (en) | 2023-08-17 |
| EP4476239A1 (en) | 2024-12-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A00 | Application filed |
Free format text: ST27 STATUS EVENT CODE: A-0-1-A10-A00-A101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: APPLICATION RECEIVED - PCT Effective date: 20240807 |
|
| A00 | Application filed |
Free format text: ST27 STATUS EVENT CODE: A-1-1-A10-A00-A102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: COMPLIANCE REQUIREMENTS DETERMINED MET Effective date: 20240808 |
|
| A15 | Pct application entered into the national or regional phase |
Free format text: ST27 STATUS EVENT CODE: A-1-1-A10-A15-X000 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: NATIONAL ENTRY REQUIREMENTS DETERMINED COMPLIANT Effective date: 20240808 |
|
| P18 | Priority claim added or amended |
Free format text: ST27 STATUS EVENT CODE: A-1-1-P10-P18-P105 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: PRIORITY CLAIM REQUIREMENTS DETERMINED COMPLIANT Effective date: 20240808 |
|
| W00 | Other event occurred |
Free format text: ST27 STATUS EVENT CODE: A-1-1-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT Effective date: 20241021 |
|
| MFA | Maintenance fee for application paid |
Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 2ND ANNIV.) - STANDARD Year of fee payment: 2 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-1-1-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20250211 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-1-1-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT Effective date: 20250211 Free format text: ST27 STATUS EVENT CODE: A-1-1-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20250211 |
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| MFA | Maintenance fee for application paid |
Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 3RD ANNIV.) - STANDARD Year of fee payment: 3 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-1-1-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20260129 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-1-1-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20260129 |