CA3200796A1 - Pseudomonas strains and their metabolites to control plant diseases - Google Patents
Pseudomonas strains and their metabolites to control plant diseasesInfo
- Publication number
- CA3200796A1 CA3200796A1 CA3200796A CA3200796A CA3200796A1 CA 3200796 A1 CA3200796 A1 CA 3200796A1 CA 3200796 A CA3200796 A CA 3200796A CA 3200796 A CA3200796 A CA 3200796A CA 3200796 A1 CA3200796 A1 CA 3200796A1
- Authority
- CA
- Canada
- Prior art keywords
- pseudomonas
- bacterial
- rejuagro
- bacteria
- pta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002207 metabolite Substances 0.000 title claims abstract description 39
- 241000589516 Pseudomonas Species 0.000 title claims description 55
- 201000010099 disease Diseases 0.000 title claims description 37
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title claims description 37
- 230000001580 bacterial effect Effects 0.000 claims abstract description 97
- 238000000034 method Methods 0.000 claims abstract description 88
- 150000001875 compounds Chemical class 0.000 claims abstract description 44
- 230000012010 growth Effects 0.000 claims abstract description 29
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims description 87
- UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 claims description 72
- 239000000203 mixture Substances 0.000 claims description 61
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 claims description 60
- 241000894006 Bacteria Species 0.000 claims description 55
- 241000588694 Erwinia amylovora Species 0.000 claims description 54
- 244000070406 Malus silvestris Species 0.000 claims description 40
- 241000695353 Pseudomonas soli Species 0.000 claims description 39
- 230000001681 protective effect Effects 0.000 claims description 39
- 229960005322 streptomycin Drugs 0.000 claims description 36
- 239000006228 supernatant Substances 0.000 claims description 33
- 235000007688 Lycopersicon esculentum Nutrition 0.000 claims description 31
- 240000003768 Solanum lycopersicum Species 0.000 claims description 31
- 238000004519 manufacturing process Methods 0.000 claims description 30
- 241000196324 Embryophyta Species 0.000 claims description 28
- 244000000010 microbial pathogen Species 0.000 claims description 22
- 241000207199 Citrus Species 0.000 claims description 21
- 241001312420 Pseudomonas mosselii Species 0.000 claims description 21
- 235000020971 citrus fruits Nutrition 0.000 claims description 21
- 241000228452 Venturia inaequalis Species 0.000 claims description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 19
- 235000011430 Malus pumila Nutrition 0.000 claims description 18
- 235000015103 Malus silvestris Nutrition 0.000 claims description 18
- 241001395385 Pseudomonas savastanoi pv. savastanoi Species 0.000 claims description 18
- 241000589655 Xanthomonas citri Species 0.000 claims description 18
- 241000233622 Phytophthora infestans Species 0.000 claims description 16
- 241000588702 Pectobacterium carotovorum subsp. carotovorum Species 0.000 claims description 14
- 241000589615 Pseudomonas syringae Species 0.000 claims description 14
- 235000013399 edible fruits Nutrition 0.000 claims description 14
- 239000007788 liquid Substances 0.000 claims description 14
- 235000020234 walnut Nutrition 0.000 claims description 13
- 241000220324 Pyrus Species 0.000 claims description 12
- 241000589771 Ralstonia solanacearum Species 0.000 claims description 12
- 235000021016 apples Nutrition 0.000 claims description 12
- 235000021017 pears Nutrition 0.000 claims description 12
- 239000004575 stone Substances 0.000 claims description 12
- 241001464977 Clavibacter michiganensis subsp. michiganensis Species 0.000 claims description 11
- 241000219104 Cucurbitaceae Species 0.000 claims description 11
- 240000005809 Prunus persica Species 0.000 claims description 11
- 235000006040 Prunus persica var persica Nutrition 0.000 claims description 11
- 244000061456 Solanum tuberosum Species 0.000 claims description 11
- 235000002595 Solanum tuberosum Nutrition 0.000 claims description 11
- 238000009472 formulation Methods 0.000 claims description 11
- 235000012015 potatoes Nutrition 0.000 claims description 11
- 241000604777 Flavobacterium columnare Species 0.000 claims description 10
- 239000006137 Luria-Bertani broth Substances 0.000 claims description 10
- 235000005087 Malus prunifolia Nutrition 0.000 claims description 10
- 241000571844 Pectobacterium parmentieri Species 0.000 claims description 10
- 241001148142 Pectobacterium atrosepticum Species 0.000 claims description 9
- 241000626572 Xanthomonas oryzae pv. oryzicola Species 0.000 claims description 9
- 230000001717 pathogenic effect Effects 0.000 claims description 9
- 235000002566 Capsicum Nutrition 0.000 claims description 8
- 241000815873 Xanthomonas euvesicatoria Species 0.000 claims description 8
- 241001187100 Dickeya dadantii Species 0.000 claims description 7
- 240000007049 Juglans regia Species 0.000 claims description 7
- 235000009496 Juglans regia Nutrition 0.000 claims description 7
- 241000758706 Piperaceae Species 0.000 claims description 7
- 241000521936 Pseudomonas amygdali pv. lachrymans Species 0.000 claims description 7
- 241000589626 Pseudomonas syringae pv. tomato Species 0.000 claims description 7
- 241000985670 Xanthomonas arboricola pv. pruni Species 0.000 claims description 7
- 239000002671 adjuvant Substances 0.000 claims description 7
- 239000004094 surface-active agent Substances 0.000 claims description 7
- 241001465180 Botrytis Species 0.000 claims description 6
- 235000008534 Capsicum annuum var annuum Nutrition 0.000 claims description 6
- 240000008384 Capsicum annuum var. annuum Species 0.000 claims description 6
- 101100117236 Drosophila melanogaster speck gene Proteins 0.000 claims description 6
- 241000758791 Juglandaceae Species 0.000 claims description 6
- 240000005561 Musa balbisiana Species 0.000 claims description 6
- 241000207836 Olea <angiosperm> Species 0.000 claims description 6
- 240000007817 Olea europaea Species 0.000 claims description 6
- 241000087479 Pseudocercospora fijiensis Species 0.000 claims description 6
- 206010039509 Scab Diseases 0.000 claims description 6
- 244000061458 Solanum melongena Species 0.000 claims description 6
- 235000002597 Solanum melongena Nutrition 0.000 claims description 6
- 241000907138 Xanthomonas oryzae pv. oryzae Species 0.000 claims description 6
- 235000021015 bananas Nutrition 0.000 claims description 6
- 239000003795 chemical substances by application Substances 0.000 claims description 6
- 235000021384 green leafy vegetables Nutrition 0.000 claims description 6
- 230000000704 physical effect Effects 0.000 claims description 6
- 235000020354 squash Nutrition 0.000 claims description 6
- 244000291564 Allium cepa Species 0.000 claims description 5
- 235000002732 Allium cepa var. cepa Nutrition 0.000 claims description 5
- 235000000832 Ayote Nutrition 0.000 claims description 5
- 241000219193 Brassicaceae Species 0.000 claims description 5
- 241000219122 Cucurbita Species 0.000 claims description 5
- 235000009854 Cucurbita moschata Nutrition 0.000 claims description 5
- 235000009804 Cucurbita pepo subsp pepo Nutrition 0.000 claims description 5
- 235000002767 Daucus carota Nutrition 0.000 claims description 5
- 244000000626 Daucus carota Species 0.000 claims description 5
- 240000007594 Oryza sativa Species 0.000 claims description 5
- 235000007164 Oryza sativa Nutrition 0.000 claims description 5
- 244000070968 Saintpaulia ionantha Species 0.000 claims description 5
- 241000208292 Solanaceae Species 0.000 claims description 5
- 235000015136 pumpkin Nutrition 0.000 claims description 5
- 235000009566 rice Nutrition 0.000 claims description 5
- 241001047487 Pectobacterium carotovorum subsp. brasiliense Species 0.000 claims description 4
- 241001469176 Xanthomonas arboricola pv. juglandis Species 0.000 claims description 4
- 238000003810 ethyl acetate extraction Methods 0.000 claims description 4
- 239000004546 suspension concentrate Substances 0.000 claims description 4
- 239000004562 water dispersible granule Substances 0.000 claims description 4
- 239000004563 wettable powder Substances 0.000 claims description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 3
- 229910052760 oxygen Inorganic materials 0.000 claims description 3
- 239000001301 oxygen Substances 0.000 claims description 3
- 239000002904 solvent Substances 0.000 claims description 3
- 239000004480 active ingredient Substances 0.000 claims description 2
- 239000000654 additive Substances 0.000 claims description 2
- 125000000217 alkyl group Chemical group 0.000 claims description 2
- 208000010824 fish disease Diseases 0.000 claims description 2
- 239000008187 granular material Substances 0.000 claims description 2
- 239000000463 material Substances 0.000 claims description 2
- 239000000843 powder Substances 0.000 claims description 2
- 230000007480 spreading Effects 0.000 claims description 2
- 238000003892 spreading Methods 0.000 claims description 2
- 241001646719 Escherichia coli O157:H7 Species 0.000 claims 2
- 239000000080 wetting agent Substances 0.000 claims 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 238000010276 construction Methods 0.000 claims 1
- 238000010413 gardening Methods 0.000 claims 1
- 229920001451 polypropylene glycol Polymers 0.000 claims 1
- 230000000845 anti-microbial effect Effects 0.000 abstract description 25
- 244000005700 microbiome Species 0.000 abstract description 5
- 230000003389 potentiating effect Effects 0.000 abstract description 4
- 239000013078 crystal Substances 0.000 description 43
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 34
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 33
- 229920001817 Agar Polymers 0.000 description 31
- 239000008272 agar Substances 0.000 description 31
- 239000001965 potato dextrose agar Substances 0.000 description 31
- 239000002609 medium Substances 0.000 description 29
- 238000003556 assay Methods 0.000 description 27
- 235000010633 broth Nutrition 0.000 description 25
- 239000000243 solution Substances 0.000 description 20
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 18
- 229910052739 hydrogen Inorganic materials 0.000 description 16
- 229940041514 candida albicans extract Drugs 0.000 description 15
- 238000000855 fermentation Methods 0.000 description 15
- 230000004151 fermentation Effects 0.000 description 15
- 230000003993 interaction Effects 0.000 description 15
- 241000894007 species Species 0.000 description 15
- 239000012138 yeast extract Substances 0.000 description 15
- 240000001987 Pyrus communis Species 0.000 description 13
- 239000000287 crude extract Substances 0.000 description 13
- 239000000539 dimer Substances 0.000 description 13
- 229930014626 natural product Natural products 0.000 description 13
- 235000014443 Pyrus communis Nutrition 0.000 description 12
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 12
- 238000006073 displacement reaction Methods 0.000 description 12
- 230000005764 inhibitory process Effects 0.000 description 12
- 230000000694 effects Effects 0.000 description 11
- 125000000623 heterocyclic group Chemical group 0.000 description 11
- 208000015181 infectious disease Diseases 0.000 description 11
- 230000002401 inhibitory effect Effects 0.000 description 11
- 239000000523 sample Substances 0.000 description 11
- 125000004429 atom Chemical group 0.000 description 10
- 238000002360 preparation method Methods 0.000 description 10
- 230000000443 biocontrol Effects 0.000 description 9
- 239000010949 copper Substances 0.000 description 9
- PVTHJAPFENJVNC-MHRBZPPQSA-N kasugamycin Chemical group N[C@H]1C[C@H](NC(=N)C(O)=O)[C@@H](C)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1O PVTHJAPFENJVNC-MHRBZPPQSA-N 0.000 description 9
- 238000012360 testing method Methods 0.000 description 9
- 239000012137 tryptone Substances 0.000 description 9
- PIFFQYJYNWXNGE-UHFFFAOYSA-N 2,4-diacetylphloroglucinol Chemical compound CC(=O)C1=C(O)C=C(O)C(C(C)=O)=C1O PIFFQYJYNWXNGE-UHFFFAOYSA-N 0.000 description 8
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 8
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 8
- 238000004458 analytical method Methods 0.000 description 8
- 230000000975 bioactive effect Effects 0.000 description 8
- 239000002024 ethyl acetate extract Substances 0.000 description 8
- 238000004128 high performance liquid chromatography Methods 0.000 description 8
- 244000052769 pathogen Species 0.000 description 8
- 239000000047 product Substances 0.000 description 8
- 239000000126 substance Substances 0.000 description 8
- 241000589540 Pseudomonas fluorescens Species 0.000 description 7
- 241000589774 Pseudomonas sp. Species 0.000 description 7
- 230000005855 radiation Effects 0.000 description 7
- 229910016523 CuKa Inorganic materials 0.000 description 6
- 229920001030 Polyethylene Glycol 4000 Polymers 0.000 description 6
- 238000013480 data collection Methods 0.000 description 6
- 239000011780 sodium chloride Substances 0.000 description 6
- 239000000725 suspension Substances 0.000 description 6
- 238000004885 tandem mass spectrometry Methods 0.000 description 6
- 238000011282 treatment Methods 0.000 description 6
- 108020004465 16S ribosomal RNA Proteins 0.000 description 5
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 5
- 241000567083 Xanthomonas arboricola Species 0.000 description 5
- 230000000843 anti-fungal effect Effects 0.000 description 5
- 230000000853 biopesticidal effect Effects 0.000 description 5
- -1 for example Chemical compound 0.000 description 5
- 239000001257 hydrogen Substances 0.000 description 5
- 238000004895 liquid chromatography mass spectrometry Methods 0.000 description 5
- 239000013642 negative control Substances 0.000 description 5
- 239000002420 orchard Substances 0.000 description 5
- 239000000575 pesticide Substances 0.000 description 5
- 108090000623 proteins and genes Proteins 0.000 description 5
- QYEWAEAWMXRMHB-YFTUCIGFSA-N (4r)-5-[[(3s,6r,9s,12r,15s,18r,21r,22r)-3-[(2s)-butan-2-yl]-6,12-bis(hydroxymethyl)-22-methyl-9,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-18-propan-2-yl-1-oxa-4,7,10,13,16,19-hexazacyclodocos-21-yl]amino]-4-[[(2s)-2-[[(3r)-3-hydroxydecanoyl]amino] Chemical compound CCCCCCC[C@@H](O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H]1[C@@H](C)OC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](C(C)C)NC1=O QYEWAEAWMXRMHB-YFTUCIGFSA-N 0.000 description 4
- 241000123650 Botrytis cinerea Species 0.000 description 4
- 241001136168 Clavibacter michiganensis Species 0.000 description 4
- 241001470247 Ralstonia solanacearum K60-1 Species 0.000 description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 4
- 244000235262 X Citroncirus webberi Species 0.000 description 4
- 235000011985 X Citroncirus webberi Nutrition 0.000 description 4
- 241000589634 Xanthomonas Species 0.000 description 4
- 241000607479 Yersinia pestis Species 0.000 description 4
- 239000003242 anti bacterial agent Substances 0.000 description 4
- 229940088710 antibiotic agent Drugs 0.000 description 4
- 229910052799 carbon Inorganic materials 0.000 description 4
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 description 4
- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 description 4
- 238000009792 diffusion process Methods 0.000 description 4
- 238000001704 evaporation Methods 0.000 description 4
- 230000008020 evaporation Effects 0.000 description 4
- 238000003818 flash chromatography Methods 0.000 description 4
- 239000008103 glucose Substances 0.000 description 4
- 238000004896 high resolution mass spectrometry Methods 0.000 description 4
- 238000000338 in vitro Methods 0.000 description 4
- 238000002955 isolation Methods 0.000 description 4
- 238000011068 loading method Methods 0.000 description 4
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 4
- 235000019341 magnesium sulphate Nutrition 0.000 description 4
- 239000013641 positive control Substances 0.000 description 4
- 101150102864 rpoD gene Proteins 0.000 description 4
- 239000000741 silica gel Substances 0.000 description 4
- 229910002027 silica gel Inorganic materials 0.000 description 4
- 238000001228 spectrum Methods 0.000 description 4
- 241000193830 Bacillus <bacterium> Species 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- 241000233866 Fungi Species 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- YZCKVEUIGOORGS-UHFFFAOYSA-N Hydrogen atom Chemical compound [H] YZCKVEUIGOORGS-UHFFFAOYSA-N 0.000 description 3
- 101100410148 Pinus taeda PT30 gene Proteins 0.000 description 3
- 101100091878 Plasmodium falciparum (isolate 3D7) rpoC2 gene Proteins 0.000 description 3
- 239000004372 Polyvinyl alcohol Substances 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 241001646398 Pseudomonas chlororaphis Species 0.000 description 3
- 241001253546 Pseudomonas entomophila Species 0.000 description 3
- 241000960608 Pseudomonas putida group Species 0.000 description 3
- 241000520892 Xanthomonas axonopodis Species 0.000 description 3
- 241000589636 Xanthomonas campestris Species 0.000 description 3
- 244000052616 bacterial pathogen Species 0.000 description 3
- 238000004364 calculation method Methods 0.000 description 3
- 150000001721 carbon Chemical group 0.000 description 3
- 238000012512 characterization method Methods 0.000 description 3
- 238000002447 crystallographic data Methods 0.000 description 3
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 3
- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 description 3
- 235000019797 dipotassium phosphate Nutrition 0.000 description 3
- 229910000396 dipotassium phosphate Inorganic materials 0.000 description 3
- 230000009977 dual effect Effects 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 239000000284 extract Substances 0.000 description 3
- 238000011081 inoculation Methods 0.000 description 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 3
- 230000000813 microbial effect Effects 0.000 description 3
- 239000002773 nucleotide Substances 0.000 description 3
- 125000003729 nucleotide group Chemical group 0.000 description 3
- 229920002451 polyvinyl alcohol Polymers 0.000 description 3
- 238000012809 post-inoculation Methods 0.000 description 3
- 238000000746 purification Methods 0.000 description 3
- 101150029016 rpo3 gene Proteins 0.000 description 3
- 101150117326 sigA gene Proteins 0.000 description 3
- 239000002689 soil Substances 0.000 description 3
- 230000003595 spectral effect Effects 0.000 description 3
- 239000008399 tap water Substances 0.000 description 3
- 235000020679 tap water Nutrition 0.000 description 3
- WEEMDRWIKYCTQM-UHFFFAOYSA-N 2,6-dimethoxybenzenecarbothioamide Chemical compound COC1=CC=CC(OC)=C1C(N)=S WEEMDRWIKYCTQM-UHFFFAOYSA-N 0.000 description 2
- QYEWAEAWMXRMHB-UHFFFAOYSA-N 8-Angeloyl-8alpha-4,9-Muuroladiene-1,8-diol Natural products CCCCCCCC(O)CC(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC1C(C)OC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(C(C)C)NC1=O QYEWAEAWMXRMHB-UHFFFAOYSA-N 0.000 description 2
- 241000251468 Actinopterygii Species 0.000 description 2
- 240000004045 Cassia javanica Species 0.000 description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 2
- 235000009917 Crataegus X brevipes Nutrition 0.000 description 2
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 description 2
- 235000009685 Crataegus X maligna Nutrition 0.000 description 2
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 description 2
- 235000009486 Crataegus bullatus Nutrition 0.000 description 2
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 description 2
- 235000009682 Crataegus limnophila Nutrition 0.000 description 2
- 240000000171 Crataegus monogyna Species 0.000 description 2
- 235000004423 Crataegus monogyna Nutrition 0.000 description 2
- 235000002313 Crataegus paludosa Nutrition 0.000 description 2
- 235000009840 Crataegus x incaedua Nutrition 0.000 description 2
- 241001515913 Dickeya dadantii 3937 Species 0.000 description 2
- 108700039887 Essential Genes Proteins 0.000 description 2
- 208000032759 Hemolytic-Uremic Syndrome Diseases 0.000 description 2
- 241000283160 Inia Species 0.000 description 2
- 241000276420 Lophius piscatorius Species 0.000 description 2
- 239000006142 Luria-Bertani Agar Substances 0.000 description 2
- 238000007476 Maximum Likelihood Methods 0.000 description 2
- 101100038261 Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB) rpo2C gene Proteins 0.000 description 2
- 241000131448 Mycosphaerella Species 0.000 description 2
- 102220623458 Pentraxin-4_H10C_mutation Human genes 0.000 description 2
- 239000002202 Polyethylene glycol Substances 0.000 description 2
- 241001515920 Pseudomonas koreensis Species 0.000 description 2
- 241000467496 Pseudomonas protegens Species 0.000 description 2
- 241001148183 Pseudomonas savastanoi Species 0.000 description 2
- 102220608658 Secreted phosphoprotein 24_H10A_mutation Human genes 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
- 102220531684 WD repeat and coiled-coil-containing protein_H12A_mutation Human genes 0.000 description 2
- 102220540093 WD repeat and coiled-coil-containing protein_H12D_mutation Human genes 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 150000007513 acids Chemical class 0.000 description 2
- 125000003368 amide group Chemical group 0.000 description 2
- 238000009635 antibiotic susceptibility testing Methods 0.000 description 2
- 238000012458 antifungal assay Methods 0.000 description 2
- 239000004599 antimicrobial Substances 0.000 description 2
- 238000002802 antimicrobial activity assay Methods 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- 235000015278 beef Nutrition 0.000 description 2
- 230000003115 biocidal effect Effects 0.000 description 2
- 238000001360 collision-induced dissociation Methods 0.000 description 2
- 239000012468 concentrated sample Substances 0.000 description 2
- 229910052802 copper Inorganic materials 0.000 description 2
- 229910000365 copper sulfate Inorganic materials 0.000 description 2
- 229910000366 copper(II) sulfate Inorganic materials 0.000 description 2
- 230000001419 dependent effect Effects 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 230000007613 environmental effect Effects 0.000 description 2
- 101150013736 gyrB gene Proteins 0.000 description 2
- 238000000589 high-performance liquid chromatography-mass spectrometry Methods 0.000 description 2
- LELOWRISYMNNSU-UHFFFAOYSA-N hydrogen cyanide Chemical compound N#C LELOWRISYMNNSU-UHFFFAOYSA-N 0.000 description 2
- KMAKOBLIOCQGJP-UHFFFAOYSA-N indole-3-carboxylic acid Chemical compound C1=CC=C2C(C(=O)O)=CNC2=C1 KMAKOBLIOCQGJP-UHFFFAOYSA-N 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 238000001294 liquid chromatography-tandem mass spectrometry Methods 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 101150012629 parE gene Proteins 0.000 description 2
- 238000003359 percent control normalization Methods 0.000 description 2
- 235000017807 phytochemicals Nutrition 0.000 description 2
- 229930000223 plant secondary metabolite Natural products 0.000 description 2
- 229920001223 polyethylene glycol Polymers 0.000 description 2
- 238000002953 preparative HPLC Methods 0.000 description 2
- QJBZDBLBQWFTPZ-UHFFFAOYSA-N pyrrolnitrin Chemical compound [O-][N+](=O)C1=C(Cl)C=CC=C1C1=CNC=C1Cl QJBZDBLBQWFTPZ-UHFFFAOYSA-N 0.000 description 2
- 230000002829 reductive effect Effects 0.000 description 2
- 101150085857 rpo2 gene Proteins 0.000 description 2
- 101150090202 rpoB gene Proteins 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 159000000000 sodium salts Chemical class 0.000 description 2
- 239000012453 solvate Substances 0.000 description 2
- 239000008223 sterile water Substances 0.000 description 2
- 229960002385 streptomycin sulfate Drugs 0.000 description 2
- 239000005720 sucrose Substances 0.000 description 2
- 230000035899 viability Effects 0.000 description 2
- 108010067142 viscosin Proteins 0.000 description 2
- VEPOHXYIFQMVHW-XOZOLZJESA-N 2,3-dihydroxybutanedioic acid (2S,3S)-3,4-dimethyl-2-phenylmorpholine Chemical compound OC(C(O)C(O)=O)C(O)=O.C[C@H]1[C@@H](OCCN1C)c1ccccc1 VEPOHXYIFQMVHW-XOZOLZJESA-N 0.000 description 1
- 238000005084 2D-nuclear magnetic resonance Methods 0.000 description 1
- IGRCWJPBLWGNPX-UHFFFAOYSA-N 3-(2-chlorophenyl)-n-(4-chlorophenyl)-n,5-dimethyl-1,2-oxazole-4-carboxamide Chemical compound C=1C=C(Cl)C=CC=1N(C)C(=O)C1=C(C)ON=C1C1=CC=CC=C1Cl IGRCWJPBLWGNPX-UHFFFAOYSA-N 0.000 description 1
- 244000003034 Arancio amaro Species 0.000 description 1
- 241000194110 Bacillus sp. (in: Bacteria) Species 0.000 description 1
- 244000063299 Bacillus subtilis Species 0.000 description 1
- 235000014469 Bacillus subtilis Nutrition 0.000 description 1
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 238000007445 Chromatographic isolation Methods 0.000 description 1
- 241000424626 Clavibacter michiganensis subsp. michiganensis NCPPB 382 Species 0.000 description 1
- 229930182827 D-tryptophan Natural products 0.000 description 1
- QIVBCDIJIAJPQS-SECBINFHSA-N D-tryptophane Chemical compound C1=CC=C2C(C[C@@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-SECBINFHSA-N 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 206010014896 Enterocolitis haemorrhagic Diseases 0.000 description 1
- 241000589565 Flavobacterium Species 0.000 description 1
- 208000019331 Foodborne disease Diseases 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 208000000420 Isovaleric acidemia Diseases 0.000 description 1
- 239000007836 KH2PO4 Substances 0.000 description 1
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 description 1
- 108010028921 Lipopeptides Proteins 0.000 description 1
- 241000218922 Magnoliophyta Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- RJQXTJLFIWVMTO-TYNCELHUSA-N Methicillin Chemical compound COC1=CC=CC(OC)=C1C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@@H]21 RJQXTJLFIWVMTO-TYNCELHUSA-N 0.000 description 1
- 241000234295 Musa Species 0.000 description 1
- 235000018290 Musa x paradisiaca Nutrition 0.000 description 1
- 241000204031 Mycoplasma Species 0.000 description 1
- 238000005481 NMR spectroscopy Methods 0.000 description 1
- 241000244206 Nematoda Species 0.000 description 1
- 206010034133 Pathogen resistance Diseases 0.000 description 1
- 239000006002 Pepper Substances 0.000 description 1
- 241000286209 Phasianidae Species 0.000 description 1
- PCNDJXKNXGMECE-UHFFFAOYSA-N Phenazine Natural products C1=CC=CC2=NC3=CC=CC=C3N=C21 PCNDJXKNXGMECE-UHFFFAOYSA-N 0.000 description 1
- 231100000674 Phytotoxicity Toxicity 0.000 description 1
- 235000016761 Piper aduncum Nutrition 0.000 description 1
- 240000003889 Piper guineense Species 0.000 description 1
- 235000017804 Piper guineense Nutrition 0.000 description 1
- 235000008184 Piper nigrum Nutrition 0.000 description 1
- 241000960592 Pseudomonas aeruginosa group Species 0.000 description 1
- 241001008519 Pseudomonas fluorescens A506 Species 0.000 description 1
- 241000589776 Pseudomonas putida Species 0.000 description 1
- 235000011400 Pyrus pyrifolia Nutrition 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 206010040047 Sepsis Diseases 0.000 description 1
- 238000012300 Sequence Analysis Methods 0.000 description 1
- 239000000589 Siderophore Substances 0.000 description 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 description 1
- 241000989208 Solimonas Species 0.000 description 1
- 206010041925 Staphylococcal infections Diseases 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 description 1
- 108010059993 Vancomycin Proteins 0.000 description 1
- 241000726445 Viroids Species 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000002528 anti-freeze Effects 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 244000000005 bacterial plant pathogen Species 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000012681 biocontrol agent Substances 0.000 description 1
- 230000032770 biofilm formation Effects 0.000 description 1
- 238000003766 bioinformatics method Methods 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 229960000074 biopharmaceutical Drugs 0.000 description 1
- 238000011957 budget and coverage analysis Methods 0.000 description 1
- 239000001110 calcium chloride Substances 0.000 description 1
- 235000011148 calcium chloride Nutrition 0.000 description 1
- 229910001628 calcium chloride Inorganic materials 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 238000011097 chromatography purification Methods 0.000 description 1
- 230000002759 chromosomal effect Effects 0.000 description 1
- 230000001332 colony forming effect Effects 0.000 description 1
- 239000000039 congener Substances 0.000 description 1
- 230000021615 conjugation Effects 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 230000001066 destructive effect Effects 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 235000021186 dishes Nutrition 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000008029 eradication Effects 0.000 description 1
- 229940093476 ethylene glycol Drugs 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 244000078673 foodborn pathogen Species 0.000 description 1
- 238000013467 fragmentation Methods 0.000 description 1
- 238000006062 fragmentation reaction Methods 0.000 description 1
- 125000000524 functional group Chemical group 0.000 description 1
- 230000002538 fungal effect Effects 0.000 description 1
- 244000053095 fungal pathogen Species 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000002054 inoculum Substances 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- BAUYGSIQEAFULO-UHFFFAOYSA-L iron(2+) sulfate (anhydrous) Chemical compound [Fe+2].[O-]S([O-])(=O)=O BAUYGSIQEAFULO-UHFFFAOYSA-L 0.000 description 1
- 229910000359 iron(II) sulfate Inorganic materials 0.000 description 1
- 108700036927 isovaleric Acidemia Proteins 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 230000005923 long-lasting effect Effects 0.000 description 1
- 238000004949 mass spectrometry Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000013028 medium composition Substances 0.000 description 1
- 208000015688 methicillin-resistant staphylococcus aureus infectious disease Diseases 0.000 description 1
- 229960003085 meticillin Drugs 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 1
- 235000019796 monopotassium phosphate Nutrition 0.000 description 1
- 235000019799 monosodium phosphate Nutrition 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 238000003012 network analysis Methods 0.000 description 1
- 230000001937 non-anti-biotic effect Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 229960000988 nystatin Drugs 0.000 description 1
- VQOXZBDYSJBXMA-NQTDYLQESA-N nystatin A1 Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/CC/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 VQOXZBDYSJBXMA-NQTDYLQESA-N 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 229960004368 oxytetracycline hydrochloride Drugs 0.000 description 1
- 230000003071 parasitic effect Effects 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 150000002988 phenazines Chemical class 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 238000013081 phylogenetic analysis Methods 0.000 description 1
- 230000000885 phytotoxic effect Effects 0.000 description 1
- 230000008635 plant growth Effects 0.000 description 1
- 239000005648 plant growth regulator Substances 0.000 description 1
- 244000000003 plant pathogen Species 0.000 description 1
- 239000013612 plasmid Substances 0.000 description 1
- GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 229960004063 propylene glycol Drugs 0.000 description 1
- 235000013772 propylene glycol Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000013138 pruning Methods 0.000 description 1
- 229960002132 pyrrolnitrin Drugs 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 238000002390 rotary evaporation Methods 0.000 description 1
- 101150098466 rpsL gene Proteins 0.000 description 1
- 229930000044 secondary metabolite Natural products 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 206010040872 skin infection Diseases 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 238000007711 solidification Methods 0.000 description 1
- 230000008023 solidification Effects 0.000 description 1
- 239000011877 solvent mixture Substances 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- MWKJTNBSKNUMFN-UHFFFAOYSA-N trifluoromethyltrimethylsilane Chemical compound C[Si](C)(C)C(F)(F)F MWKJTNBSKNUMFN-UHFFFAOYSA-N 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- 229960003165 vancomycin Drugs 0.000 description 1
- MYPYJXKWCTUITO-LYRMYLQWSA-N vancomycin Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 description 1
- MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 description 1
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- SBKWAHPUHRUGMG-CVPKQJCRSA-N viscosinamide Chemical compound CCCCCCC[C@@H](O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@@H]1[C@H](C)OC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](C(C)C)NC1=O SBKWAHPUHRUGMG-CVPKQJCRSA-N 0.000 description 1
- SBKWAHPUHRUGMG-UHFFFAOYSA-N viscosinamide Natural products CCCCCCCC(O)CC(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(=O)NC1C(C)OC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(C(C)C)NC1=O SBKWAHPUHRUGMG-UHFFFAOYSA-N 0.000 description 1
- 108010040624 viscosinamide Proteins 0.000 description 1
- 244000000028 waterborne pathogen Species 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/20—Bacteria; Substances produced thereby or obtained therefrom
- A01N63/27—Pseudomonas
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P1/00—Disinfectants; Antimicrobial compounds or mixtures thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/90—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having more than three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/38—Pseudomonas
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Environmental Sciences (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2020/054303 WO2022075969A1 (en) | 2020-10-05 | 2020-10-05 | Pseudomonas strains and their metabolites to control plant diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
CA3200796A1 true CA3200796A1 (en) | 2022-04-14 |
Family
ID=73198431
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3200796A Pending CA3200796A1 (en) | 2020-10-05 | 2020-10-05 | Pseudomonas strains and their metabolites to control plant diseases |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP4225892A1 (es) |
JP (1) | JP2023553190A (es) |
KR (1) | KR20230079416A (es) |
CN (1) | CN116367723A (es) |
CA (1) | CA3200796A1 (es) |
MX (1) | MX2023004043A (es) |
WO (1) | WO2022075969A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115747094B (zh) * | 2022-08-30 | 2024-04-02 | 内蒙古农业大学 | 一种复合菌株组合物及其应用 |
CN116694531B (zh) * | 2023-06-29 | 2024-04-05 | 四川农业大学 | 一种芽孢杆菌hlh_19及其应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011501964A (ja) | 2007-10-30 | 2011-01-20 | ベリデックス・エルエルシー | 扁平上皮細胞肺癌の予後予測プロセス |
EP2820140B1 (en) * | 2012-02-28 | 2018-01-10 | Marrone Bio Innovations, Inc. | Control of phytopathogenic microorganisms with pseudomonas sp. and substances and compositions derived therefrom |
US20220132862A1 (en) * | 2019-03-18 | 2022-05-05 | Futureco Bioscience, S.A. | Pseudomonas sp. strain, composition comprising the same, and uses thereof |
-
2020
- 2020-10-05 MX MX2023004043A patent/MX2023004043A/es unknown
- 2020-10-05 KR KR1020237014746A patent/KR20230079416A/ko unknown
- 2020-10-05 WO PCT/US2020/054303 patent/WO2022075969A1/en unknown
- 2020-10-05 CA CA3200796A patent/CA3200796A1/en active Pending
- 2020-10-05 CN CN202080105958.0A patent/CN116367723A/zh active Pending
- 2020-10-05 EP EP20804015.4A patent/EP4225892A1/en active Pending
- 2020-10-05 JP JP2023545726A patent/JP2023553190A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
KR20230079416A (ko) | 2023-06-07 |
JP2023553190A (ja) | 2023-12-20 |
EP4225892A1 (en) | 2023-08-16 |
MX2023004043A (es) | 2023-08-22 |
CN116367723A (zh) | 2023-06-30 |
WO2022075969A1 (en) | 2022-04-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US10221428B2 (en) | Compositions and methods for controlling fungal and bacterial diseases in plants | |
US20230165260A1 (en) | Pseudomonas strains and their metabolites to control plant diseases | |
JP2021169507A (ja) | 新規なパエニバチルス(paenibacillus)株、抗真菌化合物、およびそれらの使用のための方法 | |
US12089595B2 (en) | Pseudomonas strains and their metabolites to control plant diseases | |
US20150299754A1 (en) | Streptomyces microflavus strains and methods of their use to control plant diseases and pests | |
CA3200796A1 (en) | Pseudomonas strains and their metabolites to control plant diseases | |
US20220117235A1 (en) | Mosquitocidal xenorhabdus, lipopeptide and methods | |
CA3197854A1 (en) | Pseudomonas strains and their metabolites to control plant diseases | |
Fodor et al. | Novel anti-microbial peptides of Xenorhabdus origin against multidrug resistant plant pathogens | |
KR102670172B1 (ko) | 트리코더마 롱기브라키아툼 균주로부터 유래된 살균 화합물을 포함하는 식물병 방제용 조성물 및 이를 이용한 식물병 방제 방법 | |
KR102604427B1 (ko) | 트리코더마 롱기브라키아툼 균주를 포함하는 식물병 방제용 조성물 및 이를 이용한 식물병 방제 방법 | |
TW202214837A (zh) | 用於控制植物病害的假單胞菌株及其代謝產物 | |
US20070269542A1 (en) | Endophytic streptomycetes from higher plants with biological activity | |
CN116648139A (zh) | 用于防治植物病害的假单胞菌属菌株及其代谢物 | |
Sarojini | Antimicrobial peptides for fire blight control | |
Ambarsari et al. | Suppression effectivity of rice sheath blight disease by endophytic bacteria isolate artemisia. | |
KR20120042118A (ko) | 파로모마이신을 포함하는 식물병 저항성 유도제 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request |
Effective date: 20231218 |