CA3199736A1 - Formulations and methods for treating conditions of the eye - Google Patents
Formulations and methods for treating conditions of the eyeInfo
- Publication number
- CA3199736A1 CA3199736A1 CA3199736A CA3199736A CA3199736A1 CA 3199736 A1 CA3199736 A1 CA 3199736A1 CA 3199736 A CA3199736 A CA 3199736A CA 3199736 A CA3199736 A CA 3199736A CA 3199736 A1 CA3199736 A1 CA 3199736A1
- Authority
- CA
- Canada
- Prior art keywords
- pharmaceutical formulation
- administered
- azithromycin
- sub
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063117393P | 2020-11-23 | 2020-11-23 | |
| US63/117,393 | 2020-11-23 | ||
| US202163254958P | 2021-10-12 | 2021-10-12 | |
| US63/254,958 | 2021-10-12 | ||
| PCT/US2021/060653 WO2022109497A1 (en) | 2020-11-23 | 2021-11-23 | Formulations and methods for treating conditions of the eye |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3199736A1 true CA3199736A1 (en) | 2022-05-27 |
Family
ID=81658809
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3199736A Pending CA3199736A1 (en) | 2020-11-23 | 2021-11-23 | Formulations and methods for treating conditions of the eye |
Country Status (6)
| Country | Link |
|---|---|
| US (5) | US20220160668A1 (enExample) |
| EP (1) | EP4247367A4 (enExample) |
| JP (1) | JP2023550632A (enExample) |
| AU (1) | AU2021381495A1 (enExample) |
| CA (1) | CA3199736A1 (enExample) |
| WO (1) | WO2022109497A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2961369T3 (es) | 2012-03-20 | 2024-03-11 | Sight Sciences Inc | Sistemas de entrega ocular |
| US10299958B2 (en) | 2015-03-31 | 2019-05-28 | Sight Sciences, Inc. | Ocular delivery systems and methods |
| US11504270B1 (en) | 2019-09-27 | 2022-11-22 | Sight Sciences, Inc. | Ocular delivery systems and methods |
| US20220160668A1 (en) | 2020-11-23 | 2022-05-26 | Sight Sciences, Inc. | Formulations and methods for treating conditions of the eye |
| WO2022251710A2 (en) | 2021-05-28 | 2022-12-01 | Sight Sciences, Inc. | Intraocular devices, systems, and methods |
| WO2023177761A2 (en) | 2022-03-16 | 2023-09-21 | Sight Sciences, Inc. | Devices and methods for intraocular tissue manipulation |
| AU2023270196B2 (en) * | 2023-11-20 | 2025-06-26 | Dyer, Gordon Wayne DR | Method of Arthropod Egress |
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| US4957918A (en) | 1988-06-09 | 1990-09-18 | Leonard Bloom | Topical treatment of blepharitis |
| US5614545A (en) | 1988-06-09 | 1997-03-25 | Leonard Bloom | Topical composition for treatment of blepharitis |
| AT393454B (de) * | 1989-10-04 | 1991-10-25 | Ido Dr Egerer | Augentropfenzusatz |
| US6107289A (en) | 1992-04-21 | 2000-08-22 | The Schepens Eye Research Institute, Inc. | Ocular therapy in keratoconjunctivitis sicca using topically applied androgens or TGF-β |
| US6239113B1 (en) * | 1999-03-31 | 2001-05-29 | Insite Vision, Incorporated | Topical treatment or prevention of ocular infections |
| PL368642A1 (en) | 2001-11-19 | 2005-04-04 | Novartis Ag | Use of an ascomycin for the treatment of blepharitis |
| WO2004062669A1 (en) | 2003-01-16 | 2004-07-29 | Sucampo Ag | Use of a macrolide compound for treating dry eye |
| KR20050092429A (ko) | 2003-01-22 | 2005-09-21 | 니찌방 가부시기가이샤 | 안질환 치료용 경피 흡수형 제제, 그 사용, 및 안질환치료약의 눈의 국소 조직으로의 이행 방법 |
| CN101123948A (zh) | 2005-02-17 | 2008-02-13 | 千寿制药株式会社 | 眼科用固体外用药剂 |
| WO2007005421A2 (en) | 2005-07-01 | 2007-01-11 | Bausch & Lomb Incorporated | Long lasting alginate dry eye, related methods of manufacture and methods of use |
| FR2891460B1 (fr) * | 2005-09-30 | 2010-07-30 | Galderma Sa | Utilisation d'au moins un compose de la famille des avermectines pour le traitement des pathologies ophtalmiques dues au demodex folliculorum. |
| JP5186217B2 (ja) | 2005-11-28 | 2013-04-17 | 千寿製薬株式会社 | Pparアゴニスト含有医薬 |
| EP2056809A1 (en) | 2006-08-28 | 2009-05-13 | Senju Pharmaceutical Co., Ltd. | Ophthalmic percutaneous absorption type preparation |
| US20080057022A1 (en) | 2006-08-30 | 2008-03-06 | Erning Xia | Ophthalmic Pharmaceutical Compositions and Uses Thereof |
| US7659259B2 (en) | 2006-12-21 | 2010-02-09 | Bausch & Lomb Incorporated | Method of treating inflammation of the eye |
| BRPI0808410A2 (pt) | 2007-02-28 | 2015-06-23 | Aciex Therapeutics Inc | Métodos e composições para normalizar secreções da glândula meibomiana |
| WO2008137496A1 (en) * | 2007-05-04 | 2008-11-13 | Bausch & Lomb Incorporated | Compositions for reducing, ameliorating, treating, or preventing condition of dry eye and methods of making and using same |
| CN101754745A (zh) | 2007-05-07 | 2010-06-23 | 博士伦公司 | 用于缓解、改善、治疗或预防干眼症的组合物及其制备和使用方法 |
| WO2009111648A1 (en) | 2008-03-05 | 2009-09-11 | Vicus Therapeutics, Llc | Compositions and methods for mucositis and oncology therapies |
| WO2009120881A1 (en) | 2008-03-26 | 2009-10-01 | Eric Donnenfeld | Methods for improving lid margin and tear film function and treatment of lid margin desease using tetracycline family antibiotics |
| JP2011527709A (ja) * | 2008-07-10 | 2011-11-04 | インスパイアー ファーマシューティカルズ,インコーポレイティド | 眼瞼炎の治療方法 |
| EP2393355A4 (en) * | 2009-01-23 | 2012-07-25 | Inspire Pharmaceuticals Inc | METHOD FOR TREATING A DRY EYE WITH AZITHROMYCIN |
| FR2942138A1 (fr) | 2009-02-16 | 2010-08-20 | Galderma Res & Dev | Association de composes pour le traitement ou la prevention des affections dermatologiques |
| US9034830B2 (en) | 2009-10-30 | 2015-05-19 | Intratus, Inc. | Methods and compositions for sustained delivery of drugs |
| US20110294897A1 (en) | 2009-12-02 | 2011-12-01 | Bridge Pharma, Inc. | Treating Xerophthalmia With Compounds Increasing Meibomian Gland Secretion |
| WO2011106697A1 (en) * | 2010-02-25 | 2011-09-01 | Schepens Eye Research Institute | Therapeutic compositions for the treatment of dry eye disease |
| CN103140217B (zh) | 2010-08-06 | 2015-08-19 | 盖尔德马研究及发展公司 | 用于治疗或预防皮肤病的化合物的组合 |
| US20130281390A1 (en) * | 2010-12-29 | 2013-10-24 | Kurt E. Brubaker | Method for treating dry eye |
| US8900626B2 (en) | 2011-06-20 | 2014-12-02 | Senju Usa, Inc. | Transdermal drug delivery system and method of using the same |
| CA2840626A1 (en) | 2011-06-29 | 2013-01-03 | Insite Vision Incorporated | Methods of treating recurrent meibomian glands disorder and thereby decreasing the frequency of recurrence |
| JP5989780B2 (ja) * | 2011-09-14 | 2016-09-07 | フォーサイト・ビジョン5・インコーポレイテッドForsight Vision5,Inc. | 眼挿入装置および方法 |
| CN113679699B (zh) | 2012-09-12 | 2022-10-28 | 诺瓦利克有限责任公司 | 包含半氟化烷烃的混合物的组合物 |
| AU2013314303B2 (en) | 2012-09-12 | 2018-01-18 | Novaliq Gmbh | Semifluorinated alkane compositions |
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| US9044508B2 (en) | 2013-03-15 | 2015-06-02 | Insite Vision Corporation | Concentrated aqueous azalide formulations |
| US20150141328A1 (en) * | 2013-11-18 | 2015-05-21 | The Schepens Eye Research Institute | Stimulation of human meibomian gland function |
| WO2016022066A1 (en) | 2014-08-04 | 2016-02-11 | Jerry Tan Eye Surgery Pte Ltd | Pharmaceutical compositions for demodex related blepharitis and eyelid crusting |
| US9931306B2 (en) * | 2014-09-06 | 2018-04-03 | Integral Biosystems Llc | Methods and biocompatible compositions to achieve sustained drug release in the eye |
| MX2017010544A (es) | 2015-02-24 | 2018-06-18 | Univ Illinois | Metodos y composiciones para tratar la enfermedad del ojo seco y otros trastornos del ojo. |
| US9393243B1 (en) | 2015-07-14 | 2016-07-19 | Nilesh Parikh | Topical Ciprofloxacin compositions |
| US10688122B2 (en) | 2015-09-28 | 2020-06-23 | Azura Ophthalmics Ltd. | Thiol and disulfide-containing agents for increasing meibomian gland lipid secretion |
| FR3041540B1 (fr) | 2015-09-29 | 2018-10-26 | Galderma Research & Development | Composition nettoyante auto-moussante a rincer, contenant de l'ivermectine. |
| WO2017089980A1 (en) | 2015-11-26 | 2017-06-01 | Cadila Healthcare Limited | Dual ppar modulators for the treatment of diabetic retinopathy and diabetic eye diseases |
| GB201522144D0 (en) | 2015-12-15 | 2016-01-27 | Univ Manchester | Compositions and uses and methods relating thereto |
| US9439917B1 (en) | 2015-12-28 | 2016-09-13 | Shetal Amit Shah | Anti-blepharitis compositions and their use |
| CA3021394C (en) | 2016-02-04 | 2021-12-28 | Gordon Wayne Dyer | Method for breaching an oleo and hydro resistant arthropod plastron by applying a low molecular weight non-polar chemical breacher to the plastron |
| US11260035B2 (en) | 2016-10-12 | 2022-03-01 | Ps Therapies Ltd | Topical compositions and methods of use thereof |
| EP3326608A1 (en) | 2016-11-24 | 2018-05-30 | Nestlé Skin Health SA | Composition comprising avermectin compounds without solid fatty substances |
| GB201706969D0 (en) | 2017-05-02 | 2017-06-14 | Medherant Ltd | Formulation |
| US20190008920A1 (en) * | 2017-05-19 | 2019-01-10 | Ocugen, Inc. | Ophthalmic compositions and methods of use |
| JP2020525416A (ja) | 2017-06-29 | 2020-08-27 | アドヴァイテ エルエルシー. | 眼表面障害の治療及び診断 |
| AU2018372185B2 (en) | 2017-11-21 | 2024-05-16 | Cs Pharmaceuticals Limited | Compositions and methods of use for treating aberrant inflammation in peri-ocular secretory glands or at the ocular surface |
| WO2019113475A1 (en) | 2017-12-07 | 2019-06-13 | Dermavant Sciences GmbH | Topical ointment formulations and their use in treating skin conditions |
| US20230165798A1 (en) | 2018-10-12 | 2023-06-01 | Hovione Scientia | Macrocyclic lactone formulations, methods of their preparation and use of the formulations in treating pathologies secondary to ophthalmic parasites |
| US12161752B2 (en) * | 2019-08-20 | 2024-12-10 | Vishwanath Padmanabhan | Compositions and methods for the treatment of anterior blepharitis and posterior blepharitis |
| US20210052493A1 (en) | 2019-08-21 | 2021-02-25 | Joseph Sinclair | Non-aqueous anti-parasitic ointment for ophthalmological use |
| US20220347167A1 (en) | 2019-10-05 | 2022-11-03 | The Schepens Eye Research Institute, Inc. | A new treatment for meibomian gland dysfunction |
| WO2021087051A1 (en) | 2019-10-30 | 2021-05-06 | Ps Therapy Ltd. | Topical compositions and methods of use thereof |
| US20220160668A1 (en) | 2020-11-23 | 2022-05-26 | Sight Sciences, Inc. | Formulations and methods for treating conditions of the eye |
| US11872213B2 (en) | 2021-01-28 | 2024-01-16 | Glaukos Corporation | Formulations |
-
2021
- 2021-11-23 US US17/534,348 patent/US20220160668A1/en not_active Abandoned
- 2021-11-23 EP EP21895840.3A patent/EP4247367A4/en active Pending
- 2021-11-23 JP JP2023530994A patent/JP2023550632A/ja active Pending
- 2021-11-23 US US17/534,349 patent/US11419886B2/en active Active
- 2021-11-23 AU AU2021381495A patent/AU2021381495A1/en not_active Abandoned
- 2021-11-23 WO PCT/US2021/060653 patent/WO2022109497A1/en not_active Ceased
- 2021-11-23 CA CA3199736A patent/CA3199736A1/en active Pending
-
2022
- 2022-07-19 US US17/868,696 patent/US11554134B2/en active Active
- 2022-12-23 US US18/088,347 patent/US11925657B2/en active Active
-
2024
- 2024-02-01 US US18/430,551 patent/US20240415860A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20220160668A1 (en) | 2022-05-26 |
| US20230210878A1 (en) | 2023-07-06 |
| US20240415860A1 (en) | 2024-12-19 |
| US20220160743A1 (en) | 2022-05-26 |
| AU2021381495A1 (en) | 2023-06-22 |
| WO2022109497A1 (en) | 2022-05-27 |
| US11925657B2 (en) | 2024-03-12 |
| EP4247367A4 (en) | 2024-10-16 |
| JP2023550632A (ja) | 2023-12-04 |
| EP4247367A1 (en) | 2023-09-27 |
| US11554134B2 (en) | 2023-01-17 |
| US11419886B2 (en) | 2022-08-23 |
| US20220354878A1 (en) | 2022-11-10 |
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