CA3154391A1 - Thyroid hormone receptor beta agonist compounds - Google Patents

Thyroid hormone receptor beta agonist compounds Download PDF

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Publication number
CA3154391A1
CA3154391A1 CA3154391A CA3154391A CA3154391A1 CA 3154391 A1 CA3154391 A1 CA 3154391A1 CA 3154391 A CA3154391 A CA 3154391A CA 3154391 A CA3154391 A CA 3154391A CA 3154391 A1 CA3154391 A1 CA 3154391A1
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CA
Canada
Prior art keywords
alkyl
compound
groups
pharmaceutically acceptable
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3154391A
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English (en)
French (fr)
Inventor
Thorsten A. Kirschberg
Randall HALCOMB
Yingzi XU
F. Anthony Romero
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Terns Pharmaceuticals Inc
Original Assignee
Terns Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Terns Pharmaceuticals Inc filed Critical Terns Pharmaceuticals Inc
Publication of CA3154391A1 publication Critical patent/CA3154391A1/en
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA3154391A 2019-09-12 2020-09-11 Thyroid hormone receptor beta agonist compounds Pending CA3154391A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962899581P 2019-09-12 2019-09-12
US62/899,581 2019-09-12
PCT/US2020/050497 WO2021050945A1 (en) 2019-09-12 2020-09-11 Thyroid hormone receptor beta agonist compounds

Publications (1)

Publication Number Publication Date
CA3154391A1 true CA3154391A1 (en) 2021-03-18

Family

ID=74866716

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3154391A Pending CA3154391A1 (en) 2019-09-12 2020-09-11 Thyroid hormone receptor beta agonist compounds

Country Status (7)

Country Link
US (1) US12398127B2 (https=)
EP (1) EP4028008A4 (https=)
JP (2) JP2022548250A (https=)
CN (1) CN114375193B (https=)
AU (1) AU2020346057A1 (https=)
CA (1) CA3154391A1 (https=)
WO (1) WO2021050945A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
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Also Published As

Publication number Publication date
AU2020346057A1 (en) 2022-04-21
EP4028008A1 (en) 2022-07-20
JP2026027279A (ja) 2026-02-18
CN114375193B (zh) 2024-05-14
US12398127B2 (en) 2025-08-26
CN114375193A (zh) 2022-04-19
WO2021050945A1 (en) 2021-03-18
JP2022548250A (ja) 2022-11-17
US20220356177A1 (en) 2022-11-10
EP4028008A4 (en) 2023-09-13

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