CA3139049C - REAGENT STORAGE IN A TEST DEVICE - Google Patents

REAGENT STORAGE IN A TEST DEVICE

Info

Publication number
CA3139049C
CA3139049C CA3139049A CA3139049A CA3139049C CA 3139049 C CA3139049 C CA 3139049C CA 3139049 A CA3139049 A CA 3139049A CA 3139049 A CA3139049 A CA 3139049A CA 3139049 C CA3139049 C CA 3139049C
Authority
CA
Canada
Prior art keywords
targeting agent
assay device
assay
reagent
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3139049A
Other languages
English (en)
French (fr)
Other versions
CA3139049A1 (en
Inventor
Sudeep Kumar
George Sigal
Michael Tsionsky
Original Assignee
Meso Scale Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meso Scale Technologies LLC filed Critical Meso Scale Technologies LLC
Priority to CA3139049A priority Critical patent/CA3139049C/en
Priority to CA3241642A priority patent/CA3241642A1/en
Publication of CA3139049A1 publication Critical patent/CA3139049A1/en
Application granted granted Critical
Publication of CA3139049C publication Critical patent/CA3139049C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6823—Release of bound markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6832—Enhancement of hybridisation reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/30—Electrochemically active labels

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
CA3139049A 2010-10-14 2011-10-13 REAGENT STORAGE IN A TEST DEVICE Active CA3139049C (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA3139049A CA3139049C (en) 2010-10-14 2011-10-13 REAGENT STORAGE IN A TEST DEVICE
CA3241642A CA3241642A1 (en) 2010-10-14 2011-10-13 Reagent storage in an assay device

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US45511210P 2010-10-14 2010-10-14
US61/455,112 2010-10-14
CA2814680A CA2814680C (en) 2010-10-14 2011-10-13 Reagent storage in an assay device
CA3139049A CA3139049C (en) 2010-10-14 2011-10-13 REAGENT STORAGE IN A TEST DEVICE
CA3241642A CA3241642A1 (en) 2010-10-14 2011-10-13 Reagent storage in an assay device

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2814680A Division CA2814680C (en) 2010-10-14 2011-10-13 Reagent storage in an assay device

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA3241642A Division CA3241642A1 (en) 2010-10-14 2011-10-13 Reagent storage in an assay device

Publications (2)

Publication Number Publication Date
CA3139049A1 CA3139049A1 (en) 2012-04-19
CA3139049C true CA3139049C (en) 2024-10-15

Family

ID=45938967

Family Applications (3)

Application Number Title Priority Date Filing Date
CA3139049A Active CA3139049C (en) 2010-10-14 2011-10-13 REAGENT STORAGE IN A TEST DEVICE
CA2814680A Active CA2814680C (en) 2010-10-14 2011-10-13 Reagent storage in an assay device
CA3241642A Pending CA3241642A1 (en) 2010-10-14 2011-10-13 Reagent storage in an assay device

Family Applications After (2)

Application Number Title Priority Date Filing Date
CA2814680A Active CA2814680C (en) 2010-10-14 2011-10-13 Reagent storage in an assay device
CA3241642A Pending CA3241642A1 (en) 2010-10-14 2011-10-13 Reagent storage in an assay device

Country Status (5)

Country Link
US (6) US20120157332A1 (enExample)
EP (3) EP2628004A4 (enExample)
JP (1) JP5943927B2 (enExample)
CA (3) CA3139049C (enExample)
WO (1) WO2012051386A2 (enExample)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3139049C (en) 2010-10-14 2024-10-15 Meso Scale Technologies, Llc REAGENT STORAGE IN A TEST DEVICE
US10125385B2 (en) * 2013-02-25 2018-11-13 Pdl Biopharma, Inc. Electrochemiluminescence (ECL) detection reagents and related methods for measuring enzyme activity
US20160161472A1 (en) 2013-07-30 2016-06-09 President And Fellows Of Harvard College Quantitative dna-based imaging and super-resolution imaging
US20150185213A1 (en) * 2013-12-27 2015-07-02 Mag Array, Inc. Method of internal correction in one chip assay and method for measuring test substance using said method
EP3117214B1 (en) * 2014-03-11 2020-05-06 President and Fellows of Harvard College High-throughput and highly multiplexed imaging with programmable nucleic acid probes
WO2017024044A1 (en) * 2015-08-03 2017-02-09 President And Fellows Of Harvard College Enhanced electrochemical detection using nanoparticles and precipitation
CA2995204A1 (en) 2015-08-10 2017-02-16 Essenlix Corp. Bio/chemical assay devices and methods for simplified steps, small samples, accelerated speed, and ease-of-use
KR20190057445A (ko) 2015-09-14 2019-05-28 에센릭스 코프. 샘플 특히 혈액샘플을 분석하기 위한 장치와 시스템 및 그 사용 방법
US10132794B2 (en) 2015-09-14 2018-11-20 Essenlix Corporation Device and system for collecting and analyzing vapor condensate, particularly exhaled breath condensate, as well as method of using the same
US20190153552A1 (en) * 2016-05-11 2019-05-23 Mayo Foundation For Medical Education And Research Hpv screening platform
WO2018065104A1 (en) 2016-10-07 2018-04-12 Boehringer Ingelheim Vetmedica Gmbh Analysis system and method for testing a sample
CA3035141A1 (en) 2016-10-07 2018-04-12 Boehringer Ingelheim Vetmedica Gmbh Method and analysis system for testing a sample
CA3035286A1 (en) 2016-10-07 2018-04-12 Boehringer Ingelheim Vetmedica Gmbh Method and analysis system for testing a sample
TW201832726A (zh) * 2016-11-01 2018-09-16 美商海科生醫有限責任公司 可基於輸入數據建議檢測之免疫檢測系統
US10324041B2 (en) * 2016-12-21 2019-06-18 Abbott Japan Co., Ltd. Optical imaging system using lateral illumination for digital assays
US10628693B2 (en) 2016-12-21 2020-04-21 Essenlix Corporation Devices and methods for authenticating a sample and use of the same
JP7003158B2 (ja) 2017-02-07 2022-01-20 エッセンリックス コーポレーション 圧縮開放流アッセイおよび使用
CA3053002A1 (en) 2017-02-08 2018-08-16 Essenlix Corp. Bio/chemical material extraction and assay
US12569851B2 (en) 2017-02-08 2026-03-10 Essenlix Corporation Digital assay
CA3052809A1 (en) 2017-02-08 2018-08-23 Essenlix Corporation Qmax assays and applications
CN122234927A (zh) 2017-02-08 2026-06-19 上海宜晟生物科技有限公司 通过控制温度的分子操作和检测
WO2018148470A1 (en) 2017-02-08 2018-08-16 Essenlix Corporation Sample collection and handling for delayed analysis
CA3053114A1 (en) 2017-02-09 2018-08-16 Essenlix Corporation Assay using different spacing heights
JP2020507770A (ja) 2017-02-09 2020-03-12 エッセンリックス コーポレーション 比色アッセイ法
CA3053132A1 (en) 2017-02-09 2018-08-16 Essenlix Corp. Assay with amplification
CA3053295A1 (en) 2017-02-15 2018-08-23 Essenlix Corporation Assay with rapid temperature change
CN111448449B (zh) 2017-02-16 2024-08-27 上海宜晟生物科技有限公司 采用纹理化表面的测定方法及装置
US12181472B2 (en) 2017-06-12 2024-12-31 Essenlix Corporation Homogeneous assay
US11280706B2 (en) 2017-08-01 2022-03-22 Essenlix Corporation Dilution calibration
US11725227B2 (en) 2017-08-01 2023-08-15 Essenlix Corporation Devices and methods for examining drug effects on microorganisms
CN111492222A (zh) 2017-08-01 2020-08-04 Essenlix公司 样品收集、保持和测定
WO2019075244A1 (en) 2017-10-11 2019-04-18 Essenlix Corporation CONTAINING A LIQUID SAMPLE
WO2019075415A1 (en) 2017-10-13 2019-04-18 Essenlix Corporation DEVICES AND METHODS FOR AUTHENTICATING MEDICAL ANALYSIS AND USES THEREOF
US10807095B2 (en) 2017-10-26 2020-10-20 Essenlix Corporation Making and tracking assay card
US11609224B2 (en) 2017-10-26 2023-03-21 Essenlix Corporation Devices and methods for white blood cell analyses
US11237113B2 (en) 2017-10-26 2022-02-01 Essenlix Corporation Rapid pH measurement
WO2019118652A1 (en) 2017-12-12 2019-06-20 Essenlix Corporation Sample manipulation and assay with rapid temperature change
CN112534259A (zh) 2017-12-14 2021-03-19 Essenlix公司 监测毛发的装置，系统和方法
WO2019140334A1 (en) 2018-01-11 2019-07-18 Essenlix Corporation Homogeneous assay (ii)
US11885952B2 (en) 2018-07-30 2024-01-30 Essenlix Corporation Optics, device, and system for assaying and imaging
WO2021007844A1 (zh) * 2019-07-18 2021-01-21 京东方科技集团股份有限公司 微全分析系统及其工作方法、制作方法
US20210364506A1 (en) 2020-05-22 2021-11-25 Robert Bosch Gmbh Methods for detecting an amount of an analyte in a solution

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE388694B (sv) 1975-01-27 1976-10-11 Kabi Ab Sett att pavisa ett antigen exv i prov av kroppvetskor, med utnyttjande av till porost berarmaterial bundna eller adsorberande antikroppar
US4235601A (en) 1979-01-12 1980-11-25 Thyroid Diagnostics, Inc. Test device and method for its use
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4442204A (en) 1981-04-10 1984-04-10 Miles Laboratories, Inc. Homogeneous specific binding assay device and preformed complex method
US5310687A (en) 1984-10-31 1994-05-10 Igen, Inc. Luminescent metal chelate labels and means for detection
US5238808A (en) 1984-10-31 1993-08-24 Igen, Inc. Luminescent metal chelate labels and means for detection
US5591581A (en) 1986-04-30 1997-01-07 Igen, Inc. Electrochemiluminescent rhenium moieties and methods for their use
US6165729A (en) 1986-04-30 2000-12-26 Hyperion Catalysis International, Inc. Electrochemiluminescent reaction utilizing amine-derived reductant
US5147806A (en) 1988-04-29 1992-09-15 Igen, Inc. Method and apparatus for conducting electrochemiluminescence measurements
US5236849A (en) 1987-08-11 1993-08-17 Eiji Ishikawa Method of high sensitivity immunoassay
JP2606722B2 (ja) * 1988-04-05 1997-05-07 栄治 石川 超高感度抗原物質の測定法
US5308754A (en) 1988-03-21 1994-05-03 Kankare Jouko J Electrogenerated luminescence in solution
US5093268A (en) 1988-04-28 1992-03-03 Igen, Inc. Apparatus for conducting a plurality of simultaneous measurements of electrochemiluminescent phenomena
US5705402A (en) 1988-11-03 1998-01-06 Igen International, Inc. Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets
US5324457A (en) 1989-10-02 1994-06-28 Board Of Regents, The University Of Tx System Devices and methods for generating electrogenerated chemiluminescence
US5776672A (en) 1990-09-28 1998-07-07 Kabushiki Kaisha Toshiba Gene detection method
JPH04273065A (ja) * 1991-02-28 1992-09-29 Hitachi Ltd 免疫分析方法およびその分析装置
US5208535A (en) 1990-12-28 1993-05-04 Research Development Corporation Of Japan Mr position detecting device
JPH0534345A (ja) 1991-02-19 1993-02-09 Tdk Corp 化学発光を利用する抗原・抗体の測定方法
ZA929351B (en) 1991-12-11 1993-06-04 Igen Inc Electrochemiluminescent label for DNA assays.
US5541623A (en) 1993-06-02 1996-07-30 Alps Electric (U.S.A.) Inc. Temperature compensated opto-electronic circuit and mouse using same
US5786141A (en) 1994-08-26 1998-07-28 Bard; Allen J. Electrogenerated chemiluminescence labels for analysis and/or referencing
US5707799A (en) 1994-09-30 1998-01-13 Abbott Laboratories Devices and methods utilizing arrays of structures for analyte capture
JPH08178926A (ja) * 1994-10-25 1996-07-12 Sumitomo Pharmaceut Co Ltd イムノアッセイプレートおよびその用途
US5866434A (en) 1994-12-08 1999-02-02 Meso Scale Technology Graphitic nanotubes in luminescence assays
US5641623A (en) 1995-01-04 1997-06-24 Martin; Mark T. Electrochemiluminescence assay
US5643713A (en) 1995-06-07 1997-07-01 Liang; Pam Electrochemiluminescent monitoring of compounds
NZ306051A (en) 1995-03-10 1999-11-29 Meso Scale Technologies Llc Testing using electrochemiluminescence
US6207369B1 (en) 1995-03-10 2001-03-27 Meso Scale Technologies, Llc Multi-array, multi-specific electrochemiluminescence testing
US6319670B1 (en) 1995-05-09 2001-11-20 Meso Scale Technology Llp Methods and apparatus for improved luminescence assays using microparticles
US5679519A (en) 1995-05-09 1997-10-21 Oprandy; John J. Multi-label complex for enhanced sensitivity in electrochemiluminescence assay
US5589136A (en) 1995-06-20 1996-12-31 Regents Of The University Of California Silicon-based sleeve devices for chemical reactions
ATE496288T1 (de) 1995-10-11 2011-02-15 Luminex Corp Gleichzeitige mehrfachanalyse klinischer proben
GB9606850D0 (en) 1996-04-01 1996-06-05 Univ Liverpool An assay system and novel labelled compounds for use therwith
FR2764381A1 (fr) 1997-06-09 1998-12-11 Univ De Neuchatel Detecteur electrochimioluminescent
US6413783B1 (en) 1997-09-18 2002-07-02 Meso Scale Technologies, Llc Assay sonication apparatus and methodology
US6200531B1 (en) 1998-05-11 2001-03-13 Igen International, Inc. Apparatus for carrying out electrochemiluminescence test measurements
EP0962773A1 (en) 1998-06-03 1999-12-08 Mark Howard Jones Electrochemical based assay processes instrument and labels
GB9815042D0 (en) 1998-07-10 1998-09-09 Imperial College Detector
US6214552B1 (en) 1998-09-17 2001-04-10 Igen International, Inc. Assays for measuring nucleic acid damaging activities
US6136268A (en) 1999-08-17 2000-10-24 Orion Diagnostica Method for luminescence measurements
JP2003522963A (ja) * 2000-02-18 2003-07-29 アクララ バイオサイエンシーズ， インコーポレイテッド 複数部位反応デバイスおよび方法
US20030003464A1 (en) * 2000-11-27 2003-01-02 Phan Brigitte C. Dual bead assays including optical biodiscs and methods relating thereto
US20030148335A1 (en) * 2001-10-10 2003-08-07 Li Shen Detecting targets by unique identifier nucleotide tags
CA2468245A1 (en) * 2001-11-27 2003-06-05 Burstein Technologies, Inc. Magneto-optical bio-discs and systems including related methods
US20040009528A1 (en) * 2002-07-11 2004-01-15 Shyh-Yu Shaw Protein chips
US20060211055A1 (en) * 2002-11-12 2006-09-21 Caliper Life Sciences, Inc. Capture and release assay system and method
EP1583950B1 (en) * 2002-12-26 2017-04-05 Meso Scale Technologies, LLC. Assay cartridges and methods of using the same
ATE452208T1 (de) * 2004-10-08 2010-01-15 Sysmex Corp Verfahren zum nachweis einer zielsubstanz unter verwendung einer nukleinsäuresonde
EP1880218A2 (en) * 2005-04-29 2008-01-23 Beckman Coulter Fluorescence lateral flow immunoassay
US20060275852A1 (en) * 2005-06-06 2006-12-07 Montagu Jean I Assays based on liquid flow over arrays
US20070031283A1 (en) * 2005-06-23 2007-02-08 Davis Charles Q Assay cartridges and methods for point of care instruments
CA2616404A1 (en) * 2005-07-26 2007-02-01 Oregon Health & Science University Nanoparticle probes for capture, sorting and placement of targets
EP1963853B1 (en) * 2005-12-21 2016-03-09 Meso Scale Technologies, LLC Assay modules having assay reagents and methods of making and using same
JP5254949B2 (ja) * 2006-03-15 2013-08-07 マイクロニクス， インコーポレイテッド 一体型の核酸アッセイ
EP2069534A4 (en) * 2006-08-02 2010-08-11 California Inst Of Techn METHOD AND SYSTEMS FOR DETECTING AND / OR SORTING TARGETS
GB0618966D0 (en) * 2006-09-26 2006-11-08 Iti Scotland Ltd Cartridge system
CA2721085A1 (en) * 2008-04-09 2009-10-15 California Institute Of Technology Capture agents and related methods and systems for detecting and/or sorting targets
FI4060325T3 (fi) 2009-12-07 2024-09-25 Meso Scale Technologies Llc Määrityskasetin lukija
CA3139049C (en) 2010-10-14 2024-10-15 Meso Scale Technologies, Llc REAGENT STORAGE IN A TEST DEVICE

Also Published As

Publication number Publication date
US20250334571A1 (en) 2025-10-30
US20200209234A1 (en) 2020-07-02
US20120157332A1 (en) 2012-06-21
US20160349253A1 (en) 2016-12-01
US10627399B2 (en) 2020-04-21
US20220252590A1 (en) 2022-08-11
JP2013539867A (ja) 2013-10-28
EP2628004A2 (en) 2013-08-21
US12216117B2 (en) 2025-02-04
CA3241642A1 (en) 2012-04-19
WO2012051386A3 (en) 2012-07-19
EP4300100A2 (en) 2024-01-03
CA2814680C (en) 2021-11-16
EP3644058A1 (en) 2020-04-29
WO2012051386A2 (en) 2012-04-19
EP2628004A4 (en) 2014-08-20
EP4300100A3 (en) 2024-09-04
US20130316928A1 (en) 2013-11-28
US11231417B2 (en) 2022-01-25
JP5943927B2 (ja) 2016-07-05
US9797894B2 (en) 2017-10-24
CA3139049A1 (en) 2012-04-19
CA2814680A1 (en) 2012-04-19

Similar Documents

Publication Publication Date Title
CA2814680C (en) Reagent storage in an assay device
US20200191779A1 (en) Methods for conducting assays
US20250327141A1 (en) Co-binder assisted assay methods
AU2020200675B2 (en) Improved methods for conducting multiplexed assays
HK1213048B (en) Improved methods for conducting multiplexed assays

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20220215

MFA Maintenance fee for application paid

Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 13TH ANNIV.) - STANDARD

Year of fee payment: 13

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20240923

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT

Effective date: 20240923

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20240923

Q17 Modified document published

Free format text: ST27 STATUS EVENT CODE: A-4-4-Q10-Q17-Q103 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: DOCUMENT PUBLISHED

Effective date: 20241010

F11 Ip right granted following substantive examination

Free format text: ST27 STATUS EVENT CODE: A-4-4-F10-F11-X000 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: GRANT BY ISSUANCE

Effective date: 20241021

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 14TH ANNIV.) - STANDARD

Year of fee payment: 14

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20250923

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20250923