CA3123094A1 - Systems and related sample loading manifold assemblies - Google Patents

Systems and related sample loading manifold assemblies

Info

Publication number
CA3123094A1
CA3123094A1 CA3123094A CA3123094A CA3123094A1 CA 3123094 A1 CA3123094 A1 CA 3123094A1 CA 3123094 A CA3123094 A CA 3123094A CA 3123094 A CA3123094 A CA 3123094A CA 3123094 A1 CA3123094 A1 CA 3123094A1
Authority
CA
Canada
Prior art keywords
flow cell
sample
pump
channel
fluidic line
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3123094A
Other languages
English (en)
French (fr)
Inventor
Bradley Drews
Reto Schoch
Tarun Khurana
Minsoung Rhee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Illumina Inc
Original Assignee
Illumina Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illumina Inc filed Critical Illumina Inc
Publication of CA3123094A1 publication Critical patent/CA3123094A1/en
Pending legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
    • F04B49/22—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00 by means of valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B51/00—Testing machines, pumps, or pumping installations
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B53/00—Component parts, details or accessories not provided for in, or of interest apart from, groups F04B1/00 - F04B23/00 or F04B39/00 - F04B47/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0642—Filling fluids into wells by specific techniques
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/143—Quality control, feedback systems
    • B01L2200/146—Employing pressure sensors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877—Flow chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
CA3123094A 2019-09-18 2020-09-16 Systems and related sample loading manifold assemblies Pending CA3123094A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962902364P 2019-09-18 2019-09-18
US62/902,364 2019-09-18
PCT/US2020/050993 WO2021055418A1 (en) 2019-09-18 2020-09-16 Systems and related sample loading manifold assemblies

Publications (1)

Publication Number Publication Date
CA3123094A1 true CA3123094A1 (en) 2021-03-25

Family

ID=74867966

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3123094A Pending CA3123094A1 (en) 2019-09-18 2020-09-16 Systems and related sample loading manifold assemblies

Country Status (13)

Country Link
US (2) US12226767B2 (https=)
EP (1) EP4031285A4 (https=)
JP (1) JP7672338B2 (https=)
KR (1) KR20220063116A (https=)
CN (2) CN213266471U (https=)
AU (1) AU2020348297B2 (https=)
BR (1) BR112021012826A2 (https=)
CA (1) CA3123094A1 (https=)
IL (1) IL284063B2 (https=)
MX (1) MX2021006291A (https=)
SA (1) SA521422463B1 (https=)
TW (2) TWI889973B (https=)
WO (1) WO2021055418A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7618558B2 (ja) 2019-09-18 2025-01-21 イルミナ インコーポレイテッド システム及び関連するポンプマニホールドアセンブリ
CA3123094A1 (en) 2019-09-18 2021-03-25 Illumina, Inc. Systems and related sample loading manifold assemblies
WO2023076163A1 (en) * 2021-10-29 2023-05-04 Illumina, Inc. Systems and related manifold assemblies
US20230167933A1 (en) * 2021-11-30 2023-06-01 Applied Materials, Inc. Integrated manifold and switches for fluidic movement
US20240198310A1 (en) * 2022-12-16 2024-06-20 Illumina, Inc. Library Preparation Systems and Associated Methods
WO2025136718A1 (en) * 2023-12-21 2025-06-26 Illumina, Inc. Apparatus and methods for reducing the footprint of a library preparation automation platform
US20250296084A1 (en) * 2024-03-20 2025-09-25 Genemind Biosciences Co., Ltd. Method for controlling liquid inflow of liquid path system, liquid path system, apparatus, device, and storage medium
CN121266648A (zh) * 2024-07-02 2026-01-06 深圳市真迈生物科技有限公司 芯片及其制造方法

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0643173A (ja) 1992-04-23 1994-02-18 Toray Ind Inc 自動分析装置
CA2373198C (en) 1999-05-28 2011-10-11 Cepheid Cartridge for conducting a chemical reaction
DE19927850C1 (de) * 1999-06-18 2001-03-22 Danfoss As Durchflußzelle eines chemischen Analysesystems
KR20020021810A (ko) 1999-08-11 2002-03-22 야마모토 카즈모토 분석용 카트리지 및 송액 제어 장치
US8048386B2 (en) * 2002-02-25 2011-11-01 Cepheid Fluid processing and control
US20020045243A1 (en) * 2000-09-15 2002-04-18 Laska Ronald C. Fluid cartridge and method
US6764651B2 (en) 2001-11-07 2004-07-20 Varian, Inc. Fiber-optic dissolution systems, devices, and methods
EP1910688A4 (en) 2005-08-04 2010-03-03 Helicos Biosciences Corp MULTICHANNEL FLOW CELLS
US8765076B2 (en) 2006-11-14 2014-07-01 Handylab, Inc. Microfluidic valve and method of making same
KR20110030415A (ko) * 2008-01-22 2011-03-23 인터젠엑스 인크. 만능 샘플 제조 시스템 및 집적 분석 시스템에서의 용도
US8173080B2 (en) * 2008-02-14 2012-05-08 Illumina, Inc. Flow cells and manifolds having an electroosmotic pump
WO2010054000A1 (en) 2008-11-04 2010-05-14 Richard Joseph Methods, flow cells and systems for single cell analysis
WO2010141131A1 (en) 2009-06-04 2010-12-09 Lockheed Martin Corporation Multiple-sample microfluidic chip for dna analysis
EP4459241A3 (en) * 2009-12-07 2025-01-01 Meso Scale Technologies, LLC. Assay cartridge reader
US20110212453A1 (en) 2010-02-12 2011-09-01 Agarwal Abhishek K Assay card for sample acquisition, treatment and reaction
KR20130029128A (ko) 2010-07-23 2013-03-21 베크만 컬터, 인코포레이티드 실시간 pcr용 용기
US8951781B2 (en) 2011-01-10 2015-02-10 Illumina, Inc. Systems, methods, and apparatuses to image a sample for biological or chemical analysis
KR20130010433A (ko) 2011-07-18 2013-01-28 주식회사 테스 공정 챔버로부터 배출되는 폐기 가스를 이용한 발전 장치
US9334542B2 (en) 2012-04-02 2016-05-10 Life Technologies Corporation Compositions and methods for detection of microorganisms of the Mycobacterium avium complex excluding Mycobacterium avium paratuberculosis
EP2834622B1 (en) * 2012-04-03 2023-04-12 Illumina, Inc. Integrated optoelectronic read head and fluidic cartridge useful for nucleic acid sequencing
WO2013185142A1 (en) * 2012-06-08 2013-12-12 The Regents Of The University Of California Disposable world-to-chip interface for digital microfluidics
US9146248B2 (en) 2013-03-14 2015-09-29 Intelligent Bio-Systems, Inc. Apparatus and methods for purging flow cells in nucleic acid sequencing instruments
US9591268B2 (en) 2013-03-15 2017-03-07 Qiagen Waltham, Inc. Flow cell alignment methods and systems
WO2015021228A1 (en) * 2013-08-08 2015-02-12 Illumina, Inc. Fluidic system for reagent delivery to a flow cell
US9555411B2 (en) * 2013-09-30 2017-01-31 Gnubio, Inc. Microfluidic cartridge devices and methods of use and assembly
US20150224499A1 (en) 2014-02-13 2015-08-13 SFC Fluidics, Inc. Automated Microfluidic Sample Analyzer Platforms for Point of Care
WO2016050637A2 (en) 2014-09-30 2016-04-07 Sicpa Holding Sa Liquid containing polymer marker, use of a polymer marker as authentication tool, and method and device for detecting a polymer marker dissolved in a liquid
GB201418233D0 (en) * 2014-10-15 2014-11-26 Randox Lab Ltd Microfluidic chip
SG11201707568UA (en) * 2015-03-23 2017-10-30 Univ Nanyang Tech Flow cell apparatus and method of analysing biofilm development
US10634602B2 (en) * 2015-06-12 2020-04-28 Cytochip Inc. Fluidic cartridge for cytometry and additional analysis
CN113791203B (zh) 2015-06-12 2024-05-17 芯易诊有限公司 用于分析生物样品的方法
KR20180108578A (ko) * 2016-01-11 2018-10-04 일루미나, 인코포레이티드 마이크로 형광 측정기, 유체 시스템, 및 플로우 셀 래치 클램프 모듈을 구비하는 검출 장치
US10478055B2 (en) * 2016-08-31 2019-11-19 Asp Global Manufacturing Gmbh Multi-port cap for reagent container
BR112019006835A2 (pt) * 2016-10-07 2019-06-25 Boehringer Ingelheim Vetmedica Gmbh sistema de análise e método para testagem de uma amostra
RU177920U1 (ru) 2016-11-30 2018-03-15 Общество с ограниченной ответственностью "ГемаКор Лабс" (ООО "ГемаКор Лабс") Устройство мониторинга пространственно-временной динамики тромбина
GB201704747D0 (en) * 2017-01-05 2017-05-10 Illumina Inc Reagent mixing system and methods
GB201704758D0 (en) 2017-01-05 2017-05-10 Illumina Inc Reagent channel mixing systema and method
US10737267B2 (en) 2017-04-04 2020-08-11 Omniome, Inc. Fluidic apparatus and methods useful for chemical and biological reactions
SG11201908360QA (en) 2017-04-06 2019-10-30 Illumina Inc In-situ fluidic inspection
WO2018213268A1 (en) 2017-05-15 2018-11-22 Sensidyne, L.P. Airflow calibrator
US10749327B2 (en) 2017-06-27 2020-08-18 San Diego Gas & Electric Company Utility pole with tilt meters and related methods
TWI714069B (zh) 2018-05-04 2020-12-21 美商伊路米納有限公司 具有集成歧管的流動池
CA3123094A1 (en) 2019-09-18 2021-03-25 Illumina, Inc. Systems and related sample loading manifold assemblies

Also Published As

Publication number Publication date
EP4031285A1 (en) 2022-07-27
JP2022548432A (ja) 2022-11-21
BR112021012826A2 (pt) 2022-03-29
SA521422463B1 (ar) 2024-11-14
US12226767B2 (en) 2025-02-18
WO2021055418A1 (en) 2021-03-25
MX2021006291A (es) 2021-08-27
AU2020348297B2 (en) 2025-12-04
US20230285963A1 (en) 2023-09-14
CN112522065B (zh) 2024-11-19
US20210078001A1 (en) 2021-03-18
IL284063B1 (en) 2025-09-01
IL284063B2 (en) 2026-01-01
TW202229869A (zh) 2022-08-01
TWI889973B (zh) 2025-07-11
IL284063A (en) 2021-08-31
CN213266471U (zh) 2021-05-25
KR20220063116A (ko) 2022-05-17
EP4031285A4 (en) 2023-10-18
AU2020348297A1 (en) 2021-06-17
CN112522065A (zh) 2021-03-19
TWI764279B (zh) 2022-05-11
TW202113358A (zh) 2021-04-01
JP7672338B2 (ja) 2025-05-07

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