CA3121755A1

CA3121755A1 - Ire1 small molecule inhibitors

Ire1 small molecule inhibitors Download PDF

Info

Publication number: CA3121755A1
Authority: CA; Canada
Prior art keywords: optionally substituted; compound; c4alkyl; pharmaceutically acceptable; solvate
Prior art date: 2018-12-03
Legal status : Abandoned

Application number

CA3121755A

Other languages

English (en)

French (fr)

Inventor

Joseph P. Vacca

Sarah Bettigole

Current Assignee

Cornell University

Original Assignee

Cornell University

Priority date

2018-12-03

Filing date

2019-12-02

Publication date

2020-06-11

2019-12-02 Application filed by Cornell University filed Critical Cornell University

2020-06-11 Publication of CA3121755A1 publication Critical patent/CA3121755A1/en

Status Abandoned legal-status Critical Current

Links

239000003112 inhibitor Substances 0.000 title abstract description 6
150000003384 small molecules Chemical class 0.000 title abstract description 5
101100452784 Caenorhabditis elegans ire-1 gene Proteins 0.000 title 1
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238000000034 method Methods 0.000 claims abstract description 47
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201000011510 cancer Diseases 0.000 claims abstract description 25
239000007787 solid Substances 0.000 claims abstract description 16
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239000012453 solvate Substances 0.000 claims description 93
125000001072 heteroaryl group Chemical group 0.000 claims description 80
-1 substituted Chemical class 0.000 claims description 73
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