CA3119814A1 - Anellosomes for delivering protein replacement therapeutic modalities - Google Patents
Anellosomes for delivering protein replacement therapeutic modalities Download PDFInfo
- Publication number
- CA3119814A1 CA3119814A1 CA3119814A CA3119814A CA3119814A1 CA 3119814 A1 CA3119814 A1 CA 3119814A1 CA 3119814 A CA3119814 A CA 3119814A CA 3119814 A CA3119814 A CA 3119814A CA 3119814 A1 CA3119814 A1 CA 3119814A1
- Authority
- CA
- Canada
- Prior art keywords
- nucleic acid
- sequence
- anellosome
- genetic element
- orf1
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/00022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/00041—Use of virus, viral particle or viral elements as a vector
- C12N2750/00043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Mycology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862778866P | 2018-12-12 | 2018-12-12 | |
| US201862778861P | 2018-12-12 | 2018-12-12 | |
| US62/778,861 | 2018-12-12 | ||
| US62/778,866 | 2018-12-12 | ||
| PCT/US2019/065963 WO2020123795A2 (en) | 2018-12-12 | 2019-12-12 | Anellosomes for delivering protein replacement therapeutic modalities |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3119814A1 true CA3119814A1 (en) | 2020-06-18 |
Family
ID=69160356
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3119814A Pending CA3119814A1 (en) | 2018-12-12 | 2019-12-12 | Anellosomes for delivering protein replacement therapeutic modalities |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220073950A1 (https=) |
| EP (1) | EP3894569A2 (https=) |
| JP (2) | JP2022513459A (https=) |
| KR (1) | KR20210125990A (https=) |
| CN (1) | CN114127303A (https=) |
| AU (1) | AU2019395418A1 (https=) |
| BR (1) | BR112021010925A2 (https=) |
| CA (1) | CA3119814A1 (https=) |
| IL (1) | IL283781A (https=) |
| MX (1) | MX2021006945A (https=) |
| WO (1) | WO2020123795A2 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2018256925B2 (en) | 2017-04-28 | 2024-11-21 | Agrospheres, Inc. | Compositions and methods for the encapsulation and scalable delivery of agrochemicals |
| US11624061B2 (en) | 2017-04-28 | 2023-04-11 | Agrospheres, Inc. | Compositions and methods for enzyme immobilization |
| BR112020005803A2 (pt) | 2017-09-25 | 2020-12-01 | Agrospheres, Inc. | composições e métodos para produção e administração moduláveis de produtos biológicos |
| BR112021011124A2 (pt) * | 2018-12-12 | 2022-03-15 | Flagship Pioneering Innovations V Inc | Anelossomos e métodos de uso |
| AU2021288320A1 (en) * | 2020-06-12 | 2023-01-19 | Flagship Pioneering Innovations V, Inc. | Tandem anellovirus constructs |
| JP2023530451A (ja) * | 2020-06-17 | 2023-07-18 | フラッグシップ パイオニアリング イノベーションズ ブイ， インコーポレイテッド | アネロウイルスを同定し及び特徴付ける方法並びにその使用 |
| EP4267157A4 (en) * | 2020-12-23 | 2025-05-07 | Flagship Pioneering Innovations V, Inc. | IN VITRO ASSEMBLY OF ANELLOVIRUS CAPSIDS WITH RNA |
| EP4415695A4 (en) * | 2021-10-12 | 2025-11-26 | Flagship Pioneering Innovations V Inc | NEW ANELLOVECTOR COMPOSITIONS AND METHODS |
| US20250027107A1 (en) | 2021-10-18 | 2025-01-23 | Flagship Pioneering Innovations Vii, Llc | Dna compositions and related methods |
| TW202529819A (zh) | 2023-10-13 | 2025-08-01 | 美商旗艦先鋒創新公司 | 組織特異性指環載體(anellovector)遞送 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL9002008A (nl) * | 1990-09-12 | 1992-04-01 | Stichting Centr Diergeneeskund | Recombinant dna en rna en daarvan afgeleide produkten. |
| US6395472B1 (en) * | 1999-02-05 | 2002-05-28 | Abbott Laboratories | Methods of utilizing the TT virus |
| US9676828B2 (en) * | 2010-06-23 | 2017-06-13 | Deutsches Krebsforschungszentrum | Rearranged TT virus molecules for use in diagnosis, prevention and treatment of cancer and autoimmunity |
| IL271275B1 (en) * | 2017-06-13 | 2026-04-01 | Flagship Pioneering Innovations V Inc | Preparations containing croons and their uses |
| KR20210131309A (ko) * | 2018-12-12 | 2021-11-02 | 플래그쉽 파이어니어링 이노베이션스 브이, 인크. | 분비형 치료 양식을 운반하기 위한 아넬로좀 |
| BR112021011124A2 (pt) * | 2018-12-12 | 2022-03-15 | Flagship Pioneering Innovations V Inc | Anelossomos e métodos de uso |
| WO2020123753A2 (en) * | 2018-12-12 | 2020-06-18 | Flagship Pioneering Innovations V, Inc. | Anellosomes for delivering intracellular therapeutic modalities |
-
2019
- 2019-12-12 JP JP2021533527A patent/JP2022513459A/ja not_active Withdrawn
- 2019-12-12 BR BR112021010925-0A patent/BR112021010925A2/pt unknown
- 2019-12-12 MX MX2021006945A patent/MX2021006945A/es unknown
- 2019-12-12 US US17/413,297 patent/US20220073950A1/en active Pending
- 2019-12-12 KR KR1020217021776A patent/KR20210125990A/ko active Pending
- 2019-12-12 CN CN201980091248.4A patent/CN114127303A/zh active Pending
- 2019-12-12 AU AU2019395418A patent/AU2019395418A1/en active Pending
- 2019-12-12 WO PCT/US2019/065963 patent/WO2020123795A2/en not_active Ceased
- 2019-12-12 EP EP19836336.8A patent/EP3894569A2/en active Pending
- 2019-12-12 CA CA3119814A patent/CA3119814A1/en active Pending
-
2021
- 2021-06-07 IL IL283781A patent/IL283781A/en unknown
-
2024
- 2024-05-07 JP JP2024075364A patent/JP2024099833A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL283781A (en) | 2021-07-29 |
| WO2020123795A3 (en) | 2020-08-27 |
| BR112021010925A2 (pt) | 2021-08-31 |
| WO2020123795A2 (en) | 2020-06-18 |
| EP3894569A2 (en) | 2021-10-20 |
| CN114127303A (zh) | 2022-03-01 |
| AU2019395418A1 (en) | 2021-06-03 |
| US20220073950A1 (en) | 2022-03-10 |
| JP2022513459A (ja) | 2022-02-08 |
| JP2024099833A (ja) | 2024-07-25 |
| KR20210125990A (ko) | 2021-10-19 |
| MX2021006945A (es) | 2021-08-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20220726 |
|
| D15 | Examination report completed |
Free format text: ST27 STATUS EVENT CODE: A-2-2-D10-D15-D126 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: EXAMINER'S REPORT Effective date: 20241011 |
|
| MFA | Maintenance fee for application paid |
Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 5TH ANNIV.) - STANDARD Year of fee payment: 5 |
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| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20241206 |
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| U11 | Full renewal or maintenance fee paid |
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| P11 | Amendment of application requested |
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| W00 | Other event occurred |
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| P11 | Amendment of application requested |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-P102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: AMENDMENT DETERMINED COMPLIANT Effective date: 20250813 |
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| P13 | Application amended |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P13-X000 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: APPLICATION AMENDED Effective date: 20250813 |